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Effect Of Inulin Present In Chicory Roots On The Diabetes

By: Saeed Ahmad (2009-VA-642) | Dr. Sana Ullah Iqbal.
Contributor(s): Dr. Muhammad Nasir | Dr. Saima Inayat.
Material type: materialTypeLabelBookPublisher: 2016Description: 69p.Subject(s): Food Science and Human NutritionDDC classification: 2568-T Dissertation note: Diabetes is metabolic disease in which there are high glucose levels over a long period of time. The principle symptoms of high glucose are expanded thirst, regular pee, and expanded craving. Diabetes is a disease that influences the way the body uses food from the blood. It is normally a hereditarily issue of digestion system, that is showed by the inability to tolerate carbohydrates and insulin inadequacy. In 2014 around 387 million individuals have diabetes the whole way across the world and 90% of the cases were of Type 2 diabetes which is equivalent to 8.3% of the grown-up population. This proportion was equivalent for both ladies and men. From years 2012 to 2014, it is evaluated that 1.5 to 4.9 million deaths each year was because of DM. The danger of death is twice with diabetes. The normal number of individuals with diabetes is 592 million by 2035 by this rate. With more than 16 million individuals America have some type of this disease (DM). 700,000 new instances of DM are analyzed each year. Diabetes is increasing at very high rate in Pakistan. There are nearly 7.1 million DM patients in Pakistan and it is also estimated that if DM continually develop at this rate then 11.4 million patients of diabetics will be there and Pakistan would rank 10th in the world in 2030. This study is designed due to this alarming rate of diabetes in our country. Inulin present in chicory roots may be used to optimize blood glucose level in diabetic patients. Total 20 diabetic participants aged 30 to 40 years, present in Lahore, were selected for this study in two groups with 10 each participants. Chicory root powder was used as a source of inulin. 60 Chicory roots was purchased from the market. Then cleaned from dirt and then it was dried with the help of oven at temperature 55˚c.Then this dried roots were grinded with the help of grinder machine. Two group were formed. One group was control group that used only allopathic medicines specifically for diabetes. Other group was inulin group that used chicory root powder. Inulin group used both chicory root powder and medicines 1st week of the study. This was done only to ensure no side effect of chicory root powder on the participants. Next week when there was no adverse effect then participants were advised to use half of the medicine along with the chicory root powder. Then after 13 days when glucose level of the participant was on the course then eliminated the medicines and told them to use only 10 grams of chicory root powder daily. Glucose level of these patients was tested daily by the glucometer for two weeks. Then after every 5 to 7 days for 3 months. Then at the end of this period HBA1C test was carried at the hospital laboratory. In this experimental trial, we investigated the effect chicory root supplementation especially inulin has on glucose level of type 2 diabetic patients. Our results showed that three months of chicory root supplementation significantly decreased blood glucose level. My study reveals that inulin as a fiber didn’t control the diabetes but have a little effect on the glucose intake in the blood due to its fibrous nature. Data showed that the inulin supplementation slightly reduce the glucose level in the blood. First week of the supplementation was along with medicines and data showed reduction in the glucose level of blood. At initial day the average random blood glucose level was 251.2 ± 60.1 mg/dl and after 7 days it was 220 ± 53.1 mg/dl and at the end of 90th day it was 195 ± 52.3 which shows that inulin has a reducing effect on the diabetes to some 61 extent. In this study we can conclude that inulin containing chicory roots has a positive effect on the reduction of glucose level of blood (p < 0.001). The patients that use 10 grams of chicory root powder constantly were able to lower their blood glucose level and HbA1c. But it cannot be used as a medicine replacement in diabetic patients because it does not control blood glucose level to the normal range. Future Recommendations: I recommend in future that effect of inulin on the diabetic patients should be checked in relation to amount of medicines given to the patients. Researchers should check that what happens when inulin is used with different amount of medicines in diabetic patients. And also what happens when different amount of inulin is given to diabetic patients along with same medicine.
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Thesis Thesis UVAS Library
Thesis Section
Veterinary Science 2568-T (Browse shelf) Available 2568-T
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Diabetes is metabolic disease in which there are high glucose levels over a long period of time. The principle symptoms of high glucose are expanded thirst, regular pee, and expanded craving. Diabetes is a disease that influences the way the body uses food from the blood. It is normally a hereditarily issue of digestion system, that is showed by the inability to tolerate carbohydrates and insulin inadequacy.
In 2014 around 387 million individuals have diabetes the whole way across the world and 90% of the cases were of Type 2 diabetes which is equivalent to 8.3% of the grown-up population. This proportion was equivalent for both ladies and men. From years 2012 to 2014, it is evaluated that 1.5 to 4.9 million deaths each year was because of DM. The danger of death is twice with diabetes. The normal number of individuals with diabetes is 592 million by 2035 by this rate. With more than 16 million individuals America have some type of this disease (DM). 700,000 new instances of DM are analyzed each year.
Diabetes is increasing at very high rate in Pakistan. There are nearly 7.1 million DM patients in Pakistan and it is also estimated that if DM continually develop at this rate then 11.4 million patients of diabetics will be there and Pakistan would rank 10th in the world in 2030. This study is designed due to this alarming rate of diabetes in our country. Inulin present in chicory roots may be used to optimize blood glucose level in diabetic patients.
Total 20 diabetic participants aged 30 to 40 years, present in Lahore, were selected for this study in two groups with 10 each participants. Chicory root powder was used as a source of inulin.
60
Chicory roots was purchased from the market. Then cleaned from dirt and then it was dried with the help of oven at temperature 55˚c.Then this dried roots were grinded with the help of grinder machine.
Two group were formed. One group was control group that used only allopathic medicines specifically for diabetes. Other group was inulin group that used chicory root powder. Inulin group used both chicory root powder and medicines 1st week of the study. This was done only to ensure no side effect of chicory root powder on the participants. Next week when there was no adverse effect then participants were advised to use half of the medicine along with the chicory root powder. Then after 13 days when glucose level of the participant was on the course then eliminated the medicines and told them to use only 10 grams of chicory root powder daily.
Glucose level of these patients was tested daily by the glucometer for two weeks. Then after every 5 to 7 days for 3 months. Then at the end of this period HBA1C test was carried at the hospital laboratory.
In this experimental trial, we investigated the effect chicory root supplementation especially inulin has on glucose level of type 2 diabetic patients. Our results showed that three months of chicory root supplementation significantly decreased blood glucose level. My study reveals that inulin as a fiber didn’t control the diabetes but have a little effect on the glucose intake in the blood due to its fibrous nature. Data showed that the inulin supplementation slightly reduce the glucose level in the blood. First week of the supplementation was along with medicines and data showed reduction in the glucose level of blood. At initial day the average random blood glucose level was 251.2 ± 60.1 mg/dl and after 7 days it was 220 ± 53.1 mg/dl and at the end of 90th day it was 195 ± 52.3 which shows that inulin has a reducing effect on the diabetes to some
61
extent. In this study we can conclude that inulin containing chicory roots has a positive effect on the reduction of glucose level of blood (p < 0.001). The patients that use 10 grams of chicory root powder constantly were able to lower their blood glucose level and HbA1c. But it cannot be used as a medicine replacement in diabetic patients because it does not control blood glucose level to the normal range.
Future Recommendations:
I recommend in future that effect of inulin on the diabetic patients should be checked in relation to amount of medicines given to the patients. Researchers should check that what happens when inulin is used with different amount of medicines in diabetic patients. And also what happens when different amount of inulin is given to diabetic patients along with same medicine.

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