03436nam a2200205Ia 4500
20150917125659.0
150525s1994 xx 000 0 und d
eng
0370,T
Younus, M
5362
Dr. Shahzada Khurram Ashraf
5363
A Study On Pathology And Haematology Of Broiler Chickens Experimentally Infected With Salmonella
1994
The investigation was conducted to study the pathology and Haemotology of broiler chickens suffering from experimental salmonella gallinarum infection. Total of 140 day did broiler chicks were reared upto 3 weeks of age and were fed on commercial poultry feed. The birds were randomly divided into four groups i,e. A, B, C and D containing 35 chicks in each group. The inoculation of broiler chicks of experimental groups were done at the age of two weeks at a dose rate of 1ml per bird through different routas ic group A through oral route, group B through subcut, group C through I/rn and group D was kept as control. All the groups were kept under close observation to record signs and symptoms. At the age of 3 weeks (7 days of post infection) the birds of experimental and control groups were slaughtered for the study of haematological parameters (Fib estimation, TEC and TLC), gross and histopathological lesions in visceral organs (Heart, Liver, lung, spleen and kidneys)
Antemortem symptoms were recorded throughout the experiment in all the infected groups and observed listlessness with ruffled feathers, droopy wings, poor growth, weakness, loss of appetite, adherence of whitish material to vent, laboured breathing, slight depression and increased thirst. Conjunctivitis and arthritis in few cases were observed.
The postmortem changes observed in all the infected groups A, B and C at the age of 21 days (7 clays post infection) included enlarged heart, necrosis of myocardium, pericarcil tis, enlarged creamy white liver with pin point haemorrhages, congested lungs with necrotic loci ple.nomegaiy. and swollen kidneys with c1isco1.oiration and triable consistency. No lesions could be observed in control group D.
Haemotological alterations were studied in all the groups i ,e A, B, C and D. There was a significant decrease in haemoglobin concentration, total erythrocytic count amongst all the infected groups A, B and C at 21 days of age (7 clays post infection) as compared to control group D. but: the total leukocytic count showed a significant increase in all the infected groups, i, e. A, B and C as compared to control group D at the 21 clays of age.
The main histopathological lesions observed in al .1 the infected groups A, B and C at the age of 21 clays (7 clays of post infection) in heart, liver, lungs, spleen and kidneys included necrosis, haemorrhage and leukocytic: infiltration. However, in few cases fatty destrophy, congestion and degenerative changes were also observed. No histopathological lesion could be observed in control group D.
From present study it was concluded that fowl typhoid caused by Salmonella gallinarum infection resulted in higher mortality and pathological changes especially through intramuscular route as compared to other routes of infection.
Department of Pathology
4635
Dr. Mubasher
5364
Dr. Shakeel Akhter Khan
5365
Faculty of Veterinary Sciences
4292
TH
2127
2127
0
0
0
0370T
0
VS
2809
MAIN
MAIN
THE
2015-05-26
0370,T
0370,T
2015-05-26
2015-05-26
TH