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Comparative Efficacy Of Advanced Surgical Hemostats In The Canine Hepatotomy

by Syed Waseem Abbas Ali Shah (2009-VA-168) | Dr. Hamid Akbar | Prof. Dr. M.Arif Khan | Dr. Muti -ur- Rehman Khan.

Material type: book Book; Literary form: not fiction Publisher: 2016Dissertation note: The liver is a very complex and largest organ of the body. It has role in body metabolism, filtration of blood, synthesis of plasma protein, hormone production, and it is most vital organ of body. The liver has an excellent ability to recover from injury and regenerate new tissues. Liver is a highly vascularized organ and chances of bleeding are very high in hepatic surgeries. Liver is directly supplied by hepatic artery and drained by portal vein. We often come across certain problems in liver which require surgery. When an incision is given in liver there is a high risk of bleeding. In severe cases animal can lead to death due to hypovolemic shock. In this study we used latest and most advanced hemostatic agents by using Surgicel Snow and Surgicel Fibrillar to control bleeding during hepatotomy in dogs. These hemostats are affordable, safe, reliable and convenient. Considering the significance of hemostasis in surgical interventions, this project was designed to compare the advance hemostatic agents e.g. Surgicel Snow, Surgicel Fibrillar and sterile Surgical Gauzes. This study helped us to identify the best method that can be used for future surgical interventions in dogs, with the aim to minimize surgical bleeding in liver surgeries to accentuate early recovery. Conclusion On the basis of findings of this study: it was concluded Surgicel Snow is best hemostat than Surgical Fibrillar. It is the best hemostat with minimum blood loss and least effects on liver function. Availability: Items available for loan: UVAS Library [Call number: 2658-T] (1).

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Effect Of Unilateral And Bilateral Thyroidectomy On Hormonal And Biochemical Parameters In Dogs

by Mehmood Ur Rehman (2009-VA-177) | Dr. Hamid Akbar | Prof. Dr.M.Arif Khan | Dr. Muti ur Rehman Khan.

Material type: book Book; Literary form: not fiction Publisher: 2016Dissertation note: Thyroid gland is one of the most important endocrine gland of animal body. T3 and T4 are two major hormones secreted by thyroid gland. These hormones have a major role in metabolism of cells and organs. In normal thyroid both these hormones have anabolic effect. Thyroid tumors account for 1.2-3.8 % of all types of tumors in dogs. Unilateral, bilateral or subtotal thyroidectomies are practiced to remove benign or malignant thyroid carcinomas. The present study was conducted on 12 mongrel dogs. These dogs were rendered to 3 groups with 4 dogs in each group. One group acted as control, in which no surgery was performed, second group underwent unilateral removal of thyroid gland while the third group underwent bilateral removal of thyroid gland. Free thyroxine, thyroid stimulating hormone level, calcium, W.B.Cs, R.B.Cs and haemoglobin concentration were monitored for 21 days post-operatively. The data was expressed as mean and standard deviation. Results of the study were analysed by 2 samples T-test, one way ANOVA using multiple comparison test on SPSS version 16.0. Based on these results it was concluded that bilateral thyroidectomy was effective in relieving hyperthyroidism but there is a need to immediately initiate levothyroxine therapy. Free T4 level drops near to zero by day 21 and TSH level rises by many folds. On the other hand, in unilateral procedure Free T4 level remain in normal range and 75% of dogs require no levothyroxine therapy. Level of calcium in unilateral and bilateral thyroid removal remains within normal range provided parathyroid glands are preserved properly. Haemoglobin concentration in both the procedures is reduced significantly postoperatively. There is a need to monitor blood parameters postoperatively. Availability: Items available for loan: UVAS Library [Call number: 2657-T] (1).

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Use Of Xylazine And Detomidine Alone And With Ketamine Anesthesia For Caponization In Pigeons

by Ahtzaz Haider (2009-VA-413) | Prof. Dr. M.Arif Khan | Dr. Hamid Akbar | Dr. Muti -ur- Rehman Khan.

Material type: book Book; Literary form: not fiction Publisher: 2016Dissertation note: For this study, (16) sixteen pigeons were selected, the birds were allocated into four treatment groups i.e. Group A, Group B, Group C and Group D, with 4 birds each. In group A, after surgical preparation, birds were given xylazine injection intramuscularly at dose rate of 16mg per kg body weight. In group B, birds were given detomidine injection intramuscularly at dose rate of 1.4mg per kg body weight. In group C, birds were given ketamine-xylazine injection intramuscularly at the dose rate of 30mg and 8mg per kg body weight respectively. In group D, birds were given ketamine-detomidine injection with the dose rate of 30mg and 0.7mg per kg body weight respectively. While regularly checking reflexes after short intervals of time. After achieving of the surgical stage of anesthesia, the surgical operation was beginning. The data was analyzed by One Way ANOVA followed by multiple comparison tests using Statistical Package for Social Science (SPSS) version 20.0. The purpose of designed research was to compare the efficacy of anaesthesia alone and with the combination of the other anaesthesia during the surgery of the pigeons. Different parameters were used to check the efficiency of the anaesthesia. All birds were thoroughly examined to rule out any other anomaly before study. The surgery was performed at Surgery Section, Department of CMS, UVAS, Lahore for 3 months’ duration (including adaptation and postoperative period). Conclusion The verdict based explanations for better and reliable anaesthetic combination used in pigeons and to evaluate safe anaesthetic combination and to find ideal pre anaesthetic with minimum effects. We concluded that detomidine alone can be used just for non-surgical 40 procedures because it produces the light sedation but superficial analgesia with smooth induction and recovery but xylazine can also be used if detomidine is not available. Xylazine produces superficial analgesia and light sedation but for the short time comparatively. For major and minor surgeries both combinations of ketamine i.e. (K-Xp) and (K-Dp) are more reliable and safe. Both cocktails produce the deep analgesia and anaesthesia as well, with rapid and smooth induction and recovery. Availability: Items available for loan: UVAS Library [Call number: 2684-T] (1).

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