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1. An Epidemiological & Haematological Correlation Between Healthy & Tuberculous Indigenous Birds

by Azeem Ijaz | Dr. Muhammad Athar Khan | Dr. Asif | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1994Dissertation note: A total of 250 desi birds, selected randomly, from different villages of district Lahore, were divided into two groups. The group-I composed of 125 apparently healthy birds whereas 125 apparently weak and emaciated birds were present in group-IT. Avian tuberculin test was employed to diagnose the tuberculosis. A 0.1 ml of avian tuberculin (MCSM) procured from VRI, Lahore, was injected into left wattle whereas right wattle was kept as uninjected control and test was read after 48 hours. Only 6 birds (2.4%), all belonged to group-IT, were found tuberculin positive. Haematological studies of these six tuberculin positive birds were carried out along with 10 healthy desi birds for comparison. There was decrease in erythrocytic count (EC), haemoglobin value (Hb) and packed cell volume (PCV). The average values of EC, Hb and PCV of infected birds were 1.94x106/µ1, 8.86 g/dl and 22.69% respectively. On the other hand, leukocytic count (LC) was increased and found to be 37.33x10/il on average. A significant change in differential leukocytic count (DLC) was also observed with an increase in the proportion of polymorphs and monocytes and fall in lymphocytes. The lymphocyte to heterophils ratio was the inverse of that in healthy birds. On post-mortem, a large number of tubercles of varying size were noticed on liver, spleen and intestines. No birds showed lung lesion except one. Availability: Items available for loan: UVAS Library [Call number: 0389,T] (1).

2. A Study On Clinico Serilogical Observations By Experimental Aflatoxicosis In Quails

by Mahmood Farooq Qureshi | Dr. Muhammed Athar Khan | Dr. Asif | Dr. Muhammed Sarwer Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1996Dissertation note: In this project the effect of orally administered aflatoxin in feed was observed in quails. Clinicopathological picture was recorded and serum levels in tile liver and intestines of the quails were tested. At the fifth week of age healthy quails in groups A, B, C and D were given feed containing aflatoxin at a rate of 20 PPM, 40 PPM, 60 PPM and zero PPM (control group) respectively. The average (four weeks) mortality rate for groups A, B, C, and D was 21.53%, 44.80%, 54.03% and 0.07% respectively. The average four weeks case fatality rate for group A, B, C and 0 was 82.15%, 90%, 70.33% and 87.50% respectively. The average four weeks aflatoxin level in the intestinal contents was 9.09 PPM, 10.02 PPM, 11.31 PPM and 3.67 PPM in group A, B, C, and 0 respectively. The various levels of aflatoxin in the liver during the four week averaged 0.06 PPM, 5.19 PPM, 16.57 PPM and 0.05 PPM in group A, B, C and O respectively. The various levels of aflatoxin in the serum, were a four week average of 0.11 PPM, 3.69 PPM, 12.44 PPM and zero PPM in group A, B, C, and 0 respectively. The clinical signs mainifested the birds were ruffled feathers, gathering in the corners of the case, drowsiness, whitish to yellow dilcoloration of eyes, cynchitis, watery discharge from the eyes and nostrils, loose yellowish-white faeces. irregular movement with nervous signs, stiffness of the joints and dehydration. The necropsy findings were enlarged liver, gastro-entertis and petechial haemorrhages on the amasal ad serosal part of the body, deposition of a yellowish white fluid in the abdominal and thoracic cavity. There wa also pen cardial fluId and asciise in the body. Availability: Items available for loan: UVAS Library [Call number: 0495,T] (1).

3. Diagnosis And Treatment Trials Of Simple Indigestion In Sheep And Goat

by Basharat Ali | Dr. M. Sarwar Khan | Dr. Asif | Dr. M. Athar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1998Dissertation note: This research project was conducted at Outdoor 1-Jospital, College of Veterinary Sciences, Lahore. Forty animals i.e. sheep and goats suffering from simple indigestion were selected, the diagnosis was based on history clinical signs and physical examination Laboratory examination including rumen pH, serum pH, Ketone bodies estimation, protozoa motility test and cellulose digestion test were also performed to confirm the diagnosis, Animals were divided into four groups A,B,C, and D comprising 10 animals each. Animals of group A.B and, C were treated with Magnesium sulphate 50 gm. Magnesium hydro-oxide 50 gm and 1-1/2 liter normal saline once orally respectively while group D was kept as untreated control. Before treatment, rurnen pH, values 5.702±0.195, 5.681±0.180,5.466±0.074,5.813±0.276 and cellulose digestion test time values 31.3±2.4,31.3±2.3,33.6±0.7, 30.1±3.1 hours in the four groups respectively. Minor protozoa! motility was observed alongwith no serious changes in serum pH and absence of ketone bodies in all the groups. few cases of increased rumen pH were due to ingestion of legumes or urea. After treatment in group A protozoa motility was moderat while Rumen pH, cellulose digestion test time was 6.248±0.127 and 23.7±0.7 hours respectively. In group B which was treated with magnesium hydro-oxide normal rumen pH value was 6.981±0.034 and cellulose digestion test time 12.6±0.6 hours. In group C little protozoal movements were observed with minor improvement in rumen pH and cellulose digestion test time while in group D, the health of the animals further deteriorated with more disturbance in rumen pH and cellulose digestion test time values. Magnesium hydro-oxide emerged as effective and economical drug for the treatment of this condition. Availability: Items available for loan: UVAS Library [Call number: 0553,T] (1).

4. Comparative Efficacy Of Various Drugs Used Against Naturally Infected Horsed With Babesiosis

by Mamoona Ali | Dr. Khalid Pervez | Dr. Asif | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1999Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0600,T] (1).

5. Immuno Prophylaxis Of Entrerotoxaemia In Sheep And Goats

by Shahzad Jawed | Dr . Muhammad Naeem | Dr . Asif | Dr . Khushi Muhammad | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Nature of contents: biography; Literary form: Publisher: 1999Dissertation note: The present project was designed to study the comparative efficacy of three different adjuvant (Potassium aluminium sulphate, Aluminium hydroxide gel and mineral oil) for enhancing the immune potential of enterotoxaemia (combined) vaccine. T)ifferent standard biological media alongwith the supplementation of amino acids, minerals, plants and animal extracts and special modified formulated media were used for the production of alam precipitated vaccine, aluminium hydroxide gel adsorbed vaccine and oil adjuvant vaccine. It was concluded that addition of various ingredients, including yeast extracts, trace elements, amino acids, plants and animal extract, and cystine hydrochloride in proper concentration, increased the level of prototoxin and toxin in culture media due to the availability of essential required nutrients. Mouse model was chosen to study the safety and potency test of all the vaccines. The potency of all three vaccines was compared. In this experiment alam precipitated vaccine proved inferior to aluminium hydroxide gel adsorbed and oil adjuvant vaccine. In case of oil based vaccine especially in sheep the IHA antibody was significant in vaccine having potency of 750 HU/ml but on the other hand vaccine have potency 250 and 500 HU/ml were proved non significant, and the day 45 was proved significant in developing the antibody titre than that of 15 and 30 days. Same the picture was observed in case of goals that oil adjuvant vaccine was significant that of aluminized and toxoid adsorbed vaccine. It was observed that the protection afforded to goats by multivalent clostridial vaccine was higher than afforded to sheep. Availability: Items available for loan: UVAS Library [Call number: 0683,T] (1).

6. Effect Of Experimentally Induced Coccidiosis On Some Blood Parameters And Its Treatment With Embazin & Coxistac In Quails

by Anwaar Hussain, Syed | Dr. Muhammad Sarwar Khan | Dr. Asif | Dr. Muhammad Athar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1993Dissertation note: This project was designed to study the effects of experimentally induced coccidisis on some blood parameters and its treatment with Embazin and coxistac in Quails. For this purpose 300 day old quail chicks were obtained from a local hactchery and raised under standard, controlled coccidia free conditions. A commercial coccidiostat free feed was provide. At the age of 21 days. birds were divided into 4 groups comprising 60 birds each and shifted from brooder into a multistorey cage and grouped as tinder:Group A (60 quails) Infected and medicated with Embazin. Group B (60 quails) Infected and medicated with Coxistac. Group C (60 quails) Infected and non-medicated. Group D (60 quails) Non-infected-Non-medicated. Birds of group A, B and C were infected with 1 ml of coccidial inoculum having 50,000 sporulated oocysts given directly into crop. Group D was kept as control group. On fourth day post infection birds of all infected groups showed disease symptoms and at that time groups A and B was medicated with Embazin and Coxistac respectively. Four samples of blood and faeces were collected from each group on zero day, 5th day and 9th day of medication. In groups A and B Haemoglobin and Total Erythrocytic Count was lowered on 5th day and then increased on 9th day of medication oocyst count was Nil on 9th day of medication in group A and 92.30% reduction percentage was there is in group B. Haemoglobin and Total Erythrocytic Count decreased in group C upto 9th day ofmedication but oocyst count increased in this group. Increase percentage was 7.14% on 5th day and 14.28% on 9th day of medication. In group D Haemoglobin andTotal Erythrocytic Count remained almost constant and oocyst count was found Nil throughout the experimental period. The best feed conversion Ratio of 3 was recorded in group D whereas group "C" which was infected but not treated showed worst feed conversion ratio i.e. 4. Group A & B revealed intermediate F.C.R. of 3.6 and 3.8 respectively. Hishest mortality of 33.33% was recorded in group C, 13% in group B and 11.66% in group A. In group D mortality was Nil. From the findings of study it was concluded that Embazin was drug of choice for the treatment of coccidiosis in quails. Availability: Items available for loan: UVAS Library [Call number: 0372,T] (1).

7. Studies On Blood Chemistry And Histopathological Alteration Induced By Mycoplasma Gallisepticum In Broiler

by Shahida Parveen | Dr. Shakil Akhtar Khan | Dr. Asif | Dr. Shahzada Khurram Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1994Dissertation note: For this project 120 one-day-old broiler chicks were divided into two equal groups i.e. A and B. The birds in group B were challenged with Mycoplasma gallisepticum at 7 days of age, whereas those in group A were dealt with as control birds. After 21 days of post infection serum samples were obtained from the diseased as well as control birds during slaughtering. Tissue samples from lungs, liver and trachea were collected and processed for histopathological examination. The postmortem findings revealed catarrhal exudate in the flares, sinuses, trachea, lungs and oedema of airsacs wall. The lungs were congested, dark in colour and inflammed. Liver showed fibri nopurulent perihepatitis, haemorrhages and congestion. Trachea was found to have a tenacious viscous cloudy exudate which was adherent to the tracheal wall. The histopathological sections showed oedema, haemorrhages, congestion, massive infiltration of monocytes and heterophils in the lungs. The liver showed evidence of necrosis, haemorrhages and infiltration of heterophils, lymphocytes in interlobular spaces around portal vessels. The trachea showed epithelial and submucosal infiltration with lymphocytes, hypertrophy of epithelial mucous glands' and some catarrhal exudate on the mucosal surface. Sloughing of mucosa with variable degree was noted. The data, obtained by the analysis of serum, statistically indicated that the concentration of serum uric acid, serum glutamic pyruvic transaminase, serum alkaline phosphatase and serum lactic dehydrogenase was increased significantly in infected birds. Availability: Items available for loan: UVAS Library [Call number: 0396,T] (1).

8. Prevalence Of Lungworm Infestation (Dictycaulus Spp.) And Its Effect On Some Blood Parameters Of Camels During Months Of October December.

by Aslam, M | Dr. Muhammad Sarwar Khan | Dr. Asif | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1995Dissertation note: Camel is a versatile creature of the nature. Its population in Pakistan is 9,58,047 heads. Its importance is obvious from the facilities which it provides to the mankind e.g. transportation and ploughing facilities, lifting of water and pulling of carts, provision of milk meat and earning of foreign exchange. But on the other hand, camel is ignored in provision of better managemental facilities due to which it is facing many disease problems. Similarly, camel is also ignored by our scientists and a little research work has been done on camel in the world. Keeping in view all these factors, this project was designed to see the prevalence of lungworm infection in camel. This study also included haematological changes in camel blood suffering from lungworm infection. This study was conducted during the months of OctoberDecember, 1993 at Lahore abattoir. For the prevalence of lungworm infection, 150 camels suspected for lungworm infection were selected and their faecal and blood samples were collected. Regarding the prevalence of lungworm infection through faecal examination the results of present investigation show that occurrence of lungworm infection in camels is 6.00%, i.e. 9 camels out of 150 suspected were found positive. The mean values of haematological examination were observed i.e. Total leukocytic count (31.62 thousand/cm.mm), Differential leukocytic count - Neutrophils 67.88%, Eosinophils 28.77%, Basophils 3.66%, Lymphocytes 65.88%, Monocytes 5.55%, and ESR 12.20 mm/hour. Blood of camels negative to lungworm infection showed total leukocytic count mean value 19.30 thousand/cu.mm, Differential leukocytic count - Neutrophils 47.00%, Eosinophils 8.88%, Basophils 1.88%, Lymphocytes 38.55%, Monocytes 4.22% and ESR 1.85 mm/hour. Availability: Items available for loan: UVAS Library [Call number: 0405,T] (1).

9. Comparative Meat Production Potentials And Carcass Evaluation Of Buffalo And Different Breeds Of Cattle Calves

by Syed Ahmed | Prof.Dr.Talat Naseer Pasha | Dr. Asif | Dr. Nisar Ahmed.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1995Dissertation note: The most urgent need at present is to derive the maximum beef production from our existing livestock and agricultural byproducts. The present study will help us to select the most suitable livestock breed for beef production. This will further provide information to the persons interested for developing a feed lot industry in the country. In the present study the meat production potential and carcass composition of buffalo and cattle (Sahiwal, crossbred, nondescript, cholistani and dajal) was evaluted. The breeds were assigned six group I, II, III, IV, V and YI for Sahiwal, crossbred, non-descript, buffalo, Cholistani and Dajal respectively. Ten calves from each group was fattened with a control ration containing CP with a range of 10.91 to 11.23 percent and TND ranging from 66.61 to 68.70 percent, for a period of 91 days. The feed efficiency of group I-VT were 5.73, 5.98, 8.38, 7.47, 6.09 and 7.47 with an average daily weight gain of 0.796, 0.856, 0.746, 0.822, 0.840 and 0.753 kg respectively. The dressing percentage were 49.37, 49.19, 52.06, 48.54, 51.83 and 52.27 for group I to VI respectively and the difference were non significant. The percentage of blood, heart and lungs were 2.54, 2.61, 2.61, 3.06, 2.71, 2.46 percent and 0.34, 0.99, 0.39, 0.55, 0.33, 0.43 percent and 1.10, 1.12, 1.03, 1.05, 1.01 and 0.97 for group I to VI, respectively. Statistically non significant difference were found in these parameters. The percentage of liver spleen and kidneys were 1.55, 1.41, 1.52, 1.32, 1.40, 1.33 percent and 0.32, 0.38, 0.39, 0.26, 0.29, 0.30 percent and 0.28, 0.30, 0.29, 0.32,0.25 and 0.20 percent for group I to VI respectively. The only significant difference (P<0.05) between the value of kidneys. The value for other components like mesenteric fat, feet, head and skin were 0.43, 0.56, 0.54, 0.78, 0.58, 0.57 percent for mesenteric fat and 2.26, 2.29, 2.09, 2.53, 2.07 and 2.04 percent for feet 4.27, 4.10, 4.06, 4.80, 4.38 and 4.24 percent for head 10.27, 9.06, 19.10, 9.33, 10.67 and 8.70 for skin of group I to VI, respectively. The difference among all these values were non significant. The percentage ratio of meat, bone, fat and other tissue were 48.38, 52.33,54.13, 49.36, 51.39 and 53.91 percent, 33.14, 32.87, 32.61, 31.79, 36.11, 31.83 percent, 7.04, 6.05, 8.43, 12.96, 7.22, 9.19, percent and 4.83, 5.13, 4.38, 4.01, 4.61 and 3.73 for group I to VI, respectively. Only highly significant difference (P<0.01) was observed in fat component. The chemical composition of the meat revealed 77.78, 76.86, 75.75, 73.34, 76.53 and 75.90 percent moisture, 20.55, 20.12, 20.91, 21.00, 20.56 and 20.64 percent crude protein, 9.90, 7.76, 8.71, 9.71, 8.16 and 8.54 percent ether extract, 5.18, 5.47, 6.03, 6.18, 6.39 and 6.71 percent ash in group I to VI, respectively. Non significant difference were observed in chemical composition. The cost of one kg meat production (feed cost + cost of animal) from group I to VI, 13.92, 14.13, 17.57, 14.59, 17.50 and 20.25 rupees respectively. This revealed that minimum cost of meat production was in Sahiwal calves, whereas Dajal calves proved most expensive meat producer among the different groups. Availability: Items available for loan: UVAS Library [Call number: 0416,T] (1).

10. Efficacy Of Various Chemotherapeutic Agents Against Experimentally Induced Avian Mycoplasmosis In Broiler Chicks

by Naveed Ahmad Khan Niazi | Dr. Muhammad Athar Khan | Dr. Asif | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1994Dissertation note: A total number of 200 day old broiler chicks were procured to determine the drug efficacy of tiamulin, tylosin and oxytetracycline against jylycoplasma gallisepticum infection in-vivo. The organism prior to its use was verified on the basis of morphology, staining reaction, cultural characteristics and biochemical tests. These birds were divided into 5 groups each having 40 birds. The birds of all groups were infected experimentally except group A birds. On the appearance of symptoms of CRD, group C, D and E were treated with tiamulin, tylosin and oxytetracycline respectively at the recommended doses of manufacturers for three consecutive days. The birds of group B were kept as untreated control. The efficacy of each drug was based upon morbidity percentage, mortality percentage, case fatality, clinical symptoms, feed-intake and necropsy lesions on postmortem. The tiamulin proved superior over other two drugs as only one bird died unlike tylosin-treated group D which recorded 2.5% mortality. The oxytetracycline treated group E showed 7.5% mortality with the death of 2 birds. A total of 29 birds revealed no pathological lesion at necropsy in contrast to group E birds showing only 27 birds without necropsy lesions of CRD. The feed-intake was poorest in group E and was remained normal in both group C and D. After 144 hours post medication, the clearance of lesions were 96.6%, 90% and 76.6% for group C, D and E respectively. Availability: Items available for loan: UVAS Library [Call number: 0469,T] (1).

11. Effects Of A Live Coccidial Vaccine On Browth Traits And Immune Response In Broiler Chickens

by Azam Ali Nasir | Dr. Javed Rashed | Dr. Asif | Dr. Shakil Akhtar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1997Dissertation note: One hundred day old broiler chicks at the age of two days were randomly divided into four groups A, B, C and D. Group B, C and D were vaccinated orally with Cocci-vac on 3rd, 10th and 20th day of age respectively, while group A was kept as non-vaccinated control. At the age of 35 days, all the birds of each group were challenged with coccidial oocysts and the effects of Cocci-vac in controlling coccidiosis in broiler chicks as well as its effects on immune response and growth traits were studied. The immunogenic effects of Cocci-vac were recorded by challenging the birds with sporulated oocysts. In vaccinated groups (B, C and D) the immunity was better than non-vaccinated control group (A), as there were reduced or no signs of coccidiosis in vaccinated groups. The data obtained from oocysts count per gram of feces showed that the number of oocysts was 28290 and 33830 in group A (control) and 14685 and 16480 in group B (vaccinated) on 7th and 10th day post challenge, while group C had not shown any oocysts count throughout the experimental period. However, group D had shown oocysts count 3240 on 10th day post challenge but not on 7th day. The data obtained from analysis of antibody titers against Newcastle disease on 14th, 28th and 42nd day of experiment, revealed that the GM HI titers of group A (control) was slightly better (181 and 119.4) than other groups B (168.9 and 104), C (104 and 78.8) and group D (168.9 and 55.7) on 14th and 28th day but the lowest (9.8) in group A on 42nd day than other groups B (14.9), C (19.7) and D (13.9). The gross pathological study of intestine showed serosal changes (inflammation and haemorrhages) and mucosal changes (thickened wall, haemorrhages and blood tinged contents), while liver showed discolouration. These changes were much prominent in group A as compared to group B. Spleen and bursa of Fabricius represented no lesions. The data obtained by analysis of weight gain and FCR showed better weight gain (1614, 1783 and 1720) in groups B, C and D respectively and FCR 2.35, 2.24 and 2.26 in groups B, C and D respectively, in vaccinated groups as compared to control .group 'A' (Weight gain 1301 and FCR 2.45). However, within the vaccinated group C showed the best results. Availability: Items available for loan: UVAS Library [Call number: 0538,T] (1).

12. Treatment Of Experimentally Induced Coccidiosis And Its Effect On Various Blood Components In Quails

by Hameed, A | Dr. M. Sarwar Khan | Dr. Asif | Dr. Khalid Pervez | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1999Dissertation note: This project was designed to study the effect of experimentally induced coccidiosis on some blood parameters and its treatment with Amprolium 20% and Suiphadimidine alone and with Vitamin A and Vitamin K supplementation in quails. For this purpose one hundred and eighty (180) quails of two weeks old were obtained and reared controlled coccidia free conditions and provided coccidiostat free feed. At the age of 3 weeks birds were divided into 6 groups (i.e. A, B, C, D, E and F) comprising 30 birds in each groups. Group-A: Infected and medicated with Amprolium. Group-B: Infected and medicated with Sulphadimidine sodium. Group-C: Infected and medicated with Amprolium and Vitamins A&K. Group-D: Infected and medicated with Suiphadimidine sodium and Vitamins A&K. Group-E: Infected and non medicated. Group-F: Non infected non-medicated (Control). The clinical symptoms were more pronounced in those birds which were treated with Suiphadimidine and Amprolium without any supplementation of Vitamins A and K. The mortality rate lower and OPG was nil at 12th day of medication in the group which was treated with Amprolium and Vitamins A&K supplementation than the other groups. Feed conversion ratio (FCR) and average weight gain of the birds was significantly improved by the addition of Vitamins A and K supplementation with Sulphadimidine and Amprolium than of the birds which were medicated without any vitamin supplementation. The average FCR of those groups which were medicated without vitamin supplementation and with vitamin supplementation were calculated as 3.9, 4.2, 3.7 and 3.9, respectively. Haemoglobin estimation was also improved in the groups which were treated with the supplementation of vitamin A and vitamin K. And highest haemoglobin value was estimated in group C (9.8 gm/100 ml at 12th day of medication), which was medicated with Amprolium and vitamin A and vitamin K supplementation. The study showed efficacy of Amproliurn and Suiphadimidine with Supplementation for vitamins A and K in descending order. Amprolium with supplementation of vitamins A and K was proved to be best drug against coccidiosis in quails. Availability: Items available for loan: UVAS Library [Call number: 0598,T] (1).

13. Comparative Efficacy Of Different Drugs Used Against Mange Mite Infestation In Sheep

by Zafar Iqbal, Syed | Dr . Lftikhar Gul Ahmad | Dr . Asif | Dr . Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2001Dissertation note: Parasitic inFestation arc the major problem that hinder in the smooth rearing of sheep. Among the parasitic infestations ecto parasites are of major importance. Among the ecto-parasites mange mites are of prime importance as they damage skin, hide, wool etc. Mange mile infestation is considered to be highly responsible for substantial economic losses in the livestock industry (Hourrign, 1979). The present study was conducted to determine the comparative efficacy of different drugs used against mange mites in sheep. For this purpose a total of 60 animals diagnosed positive by skin scraping technique (Tarry, 1991) were randomly divided into 3 groups (A, B and C) each group comprising of 20 animals. Group A was treated with Ivojec (Ivernwctin 1%) at a dose rate of lml/50 kg body weight. Group B was treated with Seguvon (Trichiorphon) at a dose rate of 10gm/lit/animal. Group C was kept as positive untreated control. Observations were made at one week intervals for 3 weeks. The overall efficacy of Ivermectin and Seguvon at the end of study was 90% and 80% respectively. Animals were also observed for any side effect of the product. No side effect was observed during and after the study completion in both groups i.e. A and B group. No spontaneous recovery was noted in control group. From the present study it is concluded that Ivojec (Ivermectin) is the drug of choice for the treatment of mange mite infestation in sheep. Availability: Items available for loan: UVAS Library [Call number: 0677,T] (1).

14. Preparation & Evaluation Of Alum Precipitated & Oil Based Haemorrhagic Septicaemia Vaccines

by Dr . Khushi Muhammad Zulfiqar Ali | Dr . Khushi Muhammad | Dr . Asif | Dr . Lrshad Hussain | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1998Dissertation note: Pasteurcila multocida was isolated and characterised on the basis of cultural biochemical serological and pathogenicitytests.The dense culture of the organism was achieved in a fermenter that was provided sterilized air during incubation. Two types of the formalin inactivated Pastcurclla multocida vaccines (oil-based and alum precipitated) were prepared and their efficacy was evaluated in bovine. It was observed that oil-based haemorrhagic septicacmia (HS) vaccine induced high level of indirect haemalutiiiating (IHA) antibodies in the vaccinated cattle which persisted for more than 6 months. In contrast, alum precipitated HS vaccine induced immunity breakdown in the cattle with high titres of IHA antibodies while induced mw level of IHA antibodies, which persisted for 4 months. Availability: Items available for loan: UVAS Library [Call number: 0694,T] (1).

15. A Comparative Evaluation Of Sodium Alginate, Potasium Aluminium For Enhancing The Immunogenic Response Of Haemorrhagic Septicaemia Vaccine

by Tariq Mahmood Khan, Major | Dr . Muhammad Akram Munir | Dr . Asif | Dr . Sameera Akhtar | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1998Dissertation note: The present project was designed to study the comparative efficacy of three different adjuvants (Potassium aluminum sulphate, mineral oil and sodium alginate) for enhancing the immune potential of haemorrhagic septicemia vaccines. A special media was prepared for the production of alum precipitated vaccine, sodium alginate vaccine and oil adjuvant vaccine. It was concluded that addition of various ingredients, including yeast extracts, cane sugar, sodium chloride and casein hydrolysate in proper concentration, increased the number of bacterial population in culture media and HS organism developed its full antigenic characteristics due to availability of essential required nutrients. Mouse model was chosen to study the safety and potency test of all the three vaccines. The potency of all three vaccines was compared and calculated by a standard method of Ose and Muenstar (1968). In this experiment APV proved inferior to SAV and OAV with the log protection value of 3.2 and 3.6. Sodium alginate vaccine gave better results with log protection value of 3.9 and 4, but slightly inferior to that of oil adjuvant vaccine. However, a plus point of this vaccine is that it is easy to prepare and simple to administer. The alginate alone is non immunogenic, it forms a stable, colloidal transparent solution in water and is devoid of disadvantages in commonly used chemical oil adjuvant. Oil adjuvant vaccine provides much better results with log protection value of 5.2 and 5.8 as compared to APV and SAV. After storage at room temperature, only 1.2 % separation of oil phase occurred being for less than the tolerable limit of 5%. The final product formed was creamy and whitish in colour and evenly adhered to the surface of glass bottle. Undoubtedly advantages of alginate vaccine lie in the simplicity and easy administration but the immunity conferred by oil adjuvant vaccine is of longer duration. Availability: Items available for loan: UVAS Library [Call number: 0695,T] (1).

16. To Study The Comparative Efficacy Of Cloprostenol And Estradio For The Treatment Of Endometritis In Cross Bred

by Saeed Ahmad Barvi | Dr. Imtiaz Hussain Khan | Dr. Asif | Dr. Rashid Ahmad Ch | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Nature of contents: biography; Literary form: Publisher: 1992Dissertation note: This study was conducted to compare the efficacy of cioprostenol and estradiol for the treatment of 1st degree endornetrët:is in cross bred dairy cows. One hundred and sixty cross bred cows suffering from 1st degree endometrétis were selected amongst the animals brought for A.I. or repeat breeding at different A.I.Centres/Sub-centres in Lahore city. After detailed gynaecological examination animals were randomly divided into four treatment groups. Forty cross bred cows in group 'A' were injected cloprostenol on day 10 of oestrous cycle and cured animals were inseminated at the end of induced oestrus. Similarly were in group 'B' 40 cross bred cows were injected cloprostenol on day 10 of oestrous cycle and cured animals were inseminated at the end of oestrus that followed the induced one. in group 'C' endometretic bred cows were treated with estradiol intrauterinally for 3 alternate days of oestrous cycle and the cured animals were inseminated on next oestrus, Group 'D' comprised forty cross bred cows. This group served for all other groups as control. All the animals were inseminated without any treatment. After two months all the animals were palpated rectaly for pregnancy diagnosis. Only 144 animals could he traced for pregnancy diagnosis. While others died or were sold and transferred to untraceable places. The percent curative and conception rate observed in cloprostenol treated group 'A' (ind-oestus) were 75, 66.66, respectively. Similarly in group 'B' the percent curative and conception rate in cloprostenol treated (followed lind - oestrus) aimais were 87.50, 76.47. In estradiol treated animals the curative rate was 62.50% while conception rate observed was 60.86%. In control group only 40% animals conceived after insemination. On the basis of curative and conception rates cloprostenol was found better than stilboestrol for the treatment of 1st degree endometrtis. Moreover, in cloprostenol trente(1 group resti tt of inseminat ions in Tind oestrus was found better than induced one. Therefore, cloprostenol treatment is recommended as a drug of first choice for the treatment of 1st degree endometritis in cross bred diary cows. Availability: Items available for loan: UVAS Library [Call number: 1121,T] (1).

17. Investigation On Epidemiology And Economics Imporatanc Eof Major And Common Livestock Diseases In Distt. Gujrat

by Mohammad Riaz | Dr. Muhammad Sarwar Khan | Dr. Asif | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1990Dissertation note: Livestock sector has faced great set back in its development programmes because of the economic losses resulting from various animals diseases. Such losses, though highly colosol in nature, had never been determined precisely in the past, hence, it became a dire necessity, the present study aimed at estimating the losses caused by various animal diseases in District Gujrat and to find out the possible contributory factors. An active surveillance was conducted, in Tehsil Gujrat. The data was collected by a survey on the basis of a comprehensive questionnaire through personnel interview of livestock owners at their places. The blood samples were collected of aborted animals and serum samples were submitted to College of Veterinary Sciences, Lahore, Laboratory for diagnosis of brucellosis. In pursuance of the present study the data was analyzed statistically and the main conclusions drawn were as under. The incidence, mortality rate and fatality rate due to H.S. were in young buffalo 14.64%, 12.40% and 84.69%. In adult buffaloes were 2.36%, 1.01% and 42.79% respectively. Diseases of various categories have been given below in order of their respective rate of mortality such as abortion 0.29% in buffalo, 0.44% in cattle and 0.08% in goat. Mastitis in buffalo 0.04%, Haeinoglobinurea in buffalo 0.46% and in cows 0.44%. Milk fever in buffalo 0.17% post parturient prolapse in buffalo 0.25%, Metritis in buffalo 0.17% and in cattle 0.22%. In case of foot and mouth disease in young buffalo incidence 5.75% and in adult 11.72%. In cattle incidence was 9.01% in young and in adult 15.11%. In case of enterotoxaeinia disease in young goat, the morbidity, mortality and fatality 0.75%, 0.75% and 100% respectively. In adult goat 10.60%, 9.83% and 92.73% respectively. In case of young sheep incidence, mortality and fatality rate were 10.08%, 9.24% and 91.66% in adult sheep 10.89%, 7.26% and 66.66% respectively. A monetary loss of Rs.1.33 million was estimated annually in buffalo and cattle, sheep and goat, due to various diseases in surveyed area in District Gujrat. It is evident from the informations gathered from the respondents that the livestock owners residing at distant places from a veterinary hospital may not comfortably utilize the hospital facilities. The village ponds as the important disease spreading factor among the livestock (Nazir al. 1978) poisonous plants and entry of new animals to herd flock with out adopting precautionary measures. Availability: Items available for loan: UVAS Library [Call number: 1139,T] (1).



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