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Comparative Evaluation Of Mukteswar Strain N.D. Vaccine With Losota And Clonel.Z.58 New Castle Disease Vaccine

By: M.D.Mumtaz | Muhammed Naeem.
Contributor(s): Ata-Ur- Rehman Rizvi | Muhammed | Faculty of Veterinary Sciences.
Material type: materialTypeLabelBookPublisher: 1993Subject(s): Department of MicrobiologyDDC classification: 0333,T Dissertation note: New Castle disease still continues to he serious economic threat to poultry industry throughout the world due to its high morbidity and mortality rate. In Pakistan different vaccines are being used to control this disease. Now-a-days different N.D. vaccines are being imported and used on large scale in Pakistan without; knowing their immunogenic response. The present study with this project was conducted to evaluate the immunogenecity of our locally prepared Mukteswar strain of N. D. vaccine with imported Deivax Clone LZ 58 and Lasota strains of New Castle disease vaccines. To three groups "A", W. "C", comprising of 25 chicks each Nukteswar, 1,Z Clone 58 and Las toa ND vaccines were administered intramuscularly and group D was kept as unvaccinated control. Mukteswar ND vaccine gave high imanuanogenic response on day 14 (P.V) with Geomean HI titre of 438 which persisted on day 2i. LZ Clone 68 ND vaccine gave a Geomean HI Sitre of 362 on day 14 which also persisted on day 21. Laston vaccine gave a Geomean HI titre of antibodies on 14th day as 262 which persisted on day 21 (P. V) which was the lowest as compared to other two vaccines. All the three vaccines resisted challenge. Therefore it is observed from the above findings that Liukteswar strain of ND vaccine gave better results as compared to Clone and Lasota imported vaccines and their import on such large scale be stopped.
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Veterinary Science 0333,T (Browse shelf) Available 0333,T
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New Castle disease still continues to he serious economic threat to poultry industry throughout the world due to its high morbidity and mortality rate.

In Pakistan different vaccines are being used to control this disease. Now-a-days different N.D. vaccines are being imported and used on large scale in Pakistan without; knowing their immunogenic response.

The present study with this project was conducted to evaluate the immunogenecity of our locally prepared Mukteswar strain of N. D. vaccine with imported Deivax Clone LZ 58 and Lasota strains of New Castle disease vaccines. To three groups "A", W. "C", comprising of 25 chicks each Nukteswar, 1,Z Clone 58 and Las toa ND vaccines were administered intramuscularly and group D was kept as unvaccinated control.

Mukteswar ND vaccine gave high imanuanogenic response on day 14 (P.V) with Geomean HI titre of 438 which persisted on day 2i. LZ Clone 68 ND vaccine gave a Geomean HI Sitre of 362 on day 14 which also persisted on day 21.

Laston vaccine gave a Geomean HI titre of antibodies on 14th day as 262 which persisted on day 21 (P. V) which was the lowest as compared to other two vaccines. All the three vaccines resisted challenge. Therefore it is observed from the above findings that Liukteswar strain of ND vaccine gave better results as compared to Clone and Lasota imported vaccines and their import on such large scale be stopped.

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