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1. Prevalence Of Lymnaea Snails, In Lahore District, & Their Eradication By A Molluscicide Copper Sulphate

by Talib Hussain, Mughal | Dr. mhammad sarwar khan | Dr. Haji ahmad | Dr. Khalid parvez | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1993Dissertation note: The study was designed to know about the prevalence of the Lymnaea snails, identification of infected and non infected snails with intermediate stages of liver fluke and to recommend suitable copper sulphate dilution i.e. lmg/66 and lmg/lOO as molluscicide under laboratory and experimental pond conditions. One thousand snail/tern specimens were collected, 200 from each of four ponds and a natural habitat. The snails were collected fortnightly between October 1992 to March 1993. Prevalence of Lymnaea species was found to be 42.36% and infection of Lymnaea snails with intermediate stages of hepatica ranged between 37.50% and 68.75% in five habitats studied during the period from October 1992 to March 1993. copper sulphate dilution lmg/lO0 ml (10 PPM) was found to be effective as molluscicide and safe for other aquatic fauna and vegetation. Availability: Items available for loan: UVAS Library [Call number: 0346,T] (1).

2. Anthelmintic Efficacy Of Caesalpinia Crista, Ivermactin, Levemisole And Oxfendazole Against Toxocara Vitulorum

by Saeed Ahmad sindhu | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahimad | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1993Dissertation note: The present project was designed to test the anthelmintic efficacy of Caesalpinia crista Linn. seed (Karanjwa) at different dosage levels against Toxocara vitualorum infection in buffalo calves. During the both phases of first experiment, anthelmintic efficacy of Caesalpinia crista Linn. seed (powder) was tested at different dosage levels but anthelmintic efficacy was not observed at the dosage levels ranging from 2 gm to 6 gm/kg body weight. It was concluded in the first experiment that Caesalpinia crista Linn. seeds have no anthelmintic efficacy against Toxocara vitulorum infection in buffalo calves. During the second experiment clinical trials were conducted to test the anthelmintic efficacy of Caesalpinia crista Linn. seeds (Karanjwa), Ivermectin (Ivomec), Levamisole (Anthelmine) and Oxfendazole (Systarnex) against Toxocara vitulorum infection in buffalo calves under field conditions. Again results of second experiment support the zero percent (0%) anthelmintic efficacy of . crista Linn seeds (Powder) at the dosage level of 4 gm/kg body weight against vitulorum in buffalo calves. Anthelmintic efficacy of Ivermectin. (Ivomec, I ml/50 kg body weight), Levamisole (Anthelmine 1 ml/15 mg body weight) and oxfendazole (systamex 1 ml/5 kg body weight) was observed to be 99.30%, 98.30% and 100% respectively against Toxocara vitulorum infection in buffalo calves. Availability: Items available for loan: UVAS Library [Call number: 0360,T] (1).

3. Comparative Efficacy Of Various Drugs Against Experimentally Induced Mycoplasmosis In Quails

by Ayaz Issac J.S.Lall | Dr. Khalid Pervez | Dr. Hajid | Dr. Mohammad Athar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1994Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0377,T] (1).

4. A Study On The Prevalence Of Mange In Camels And Its Effects On Some Blood Parameters During Winter Months

by Bashir Ahmad | Dr. Muhammad Sarwar Khan | Dr. Khalid | Dr. Muhammad Athar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1993Dissertation note: Camel is a versatile creature of the Nature. Its population in Pakistan is 9,58,047 heads. Its importance is obvious from the facilities which it provides to the mankind e.g. transportation and ploughing facilities, lifting of water and pulling of carts, provision of milk meat and earning of foreign exchange. But. on the other hand, camel is ignored in provision of better managernental facilities due to which it is facing many disease problems. Similarly, camel is also ignored by our scientists and a little research work has been done on camel in the world. Keeping in view all these factors, this project was designed to see the prevalence of mange in camel. This study also include haematological changes in camel blood suffering from mange. This study was conducted during winter months of the 1992 at Lahore abattoir. For the prevalence of mange, 150 camels suspected for mange were selected and their skin scrapings and blood was collected. Skin scraping was examined with the help of microscope at Laboratory of Medicine Section, College of Veterinary Sciences, Lahore. During the study 19 camels out of 150 were found positive to mange and this is calculated as 12.66%. Regarding the 2nd portion of the study, blood of 19 mange infected cases were analysed for total leukocytic count (TLC), differential leukocytic count (DLC) and erythrocytic sedimentation rate (ESR). At the same time blood of 19 mange free camels was also examined and it was found that due to mange infection, TLC values were increased. In case of DLC, Eiosinophils and lymphocytes showed increase in their number. ESR was also increased due to infection of mange in camels. Availability: Items available for loan: UVAS Library [Call number: 0403,T] (1).

5. Prevalence Of Lungworm Infestation (Dictycaulus Spp.) And Its Effect On Some Blood Parameters Of Camels During Months Of October December.

by Aslam, M | Dr. Muhammad Sarwar Khan | Dr. Asif | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1995Dissertation note: Camel is a versatile creature of the nature. Its population in Pakistan is 9,58,047 heads. Its importance is obvious from the facilities which it provides to the mankind e.g. transportation and ploughing facilities, lifting of water and pulling of carts, provision of milk meat and earning of foreign exchange. But on the other hand, camel is ignored in provision of better managemental facilities due to which it is facing many disease problems. Similarly, camel is also ignored by our scientists and a little research work has been done on camel in the world. Keeping in view all these factors, this project was designed to see the prevalence of lungworm infection in camel. This study also included haematological changes in camel blood suffering from lungworm infection. This study was conducted during the months of OctoberDecember, 1993 at Lahore abattoir. For the prevalence of lungworm infection, 150 camels suspected for lungworm infection were selected and their faecal and blood samples were collected. Regarding the prevalence of lungworm infection through faecal examination the results of present investigation show that occurrence of lungworm infection in camels is 6.00%, i.e. 9 camels out of 150 suspected were found positive. The mean values of haematological examination were observed i.e. Total leukocytic count (31.62 thousand/cm.mm), Differential leukocytic count - Neutrophils 67.88%, Eosinophils 28.77%, Basophils 3.66%, Lymphocytes 65.88%, Monocytes 5.55%, and ESR 12.20 mm/hour. Blood of camels negative to lungworm infection showed total leukocytic count mean value 19.30 thousand/cu.mm, Differential leukocytic count - Neutrophils 47.00%, Eosinophils 8.88%, Basophils 1.88%, Lymphocytes 38.55%, Monocytes 4.22% and ESR 1.85 mm/hour. Availability: Items available for loan: UVAS Library [Call number: 0405,T] (1).

6. Estimation And Correlation Of Protein, Differential Leukocyte Count (Dlc) And Total Leukocyte Count (Tlc) In The Blood And Milk Of Sub Clinically Mastitic Buffaloes

by Fakhar uz Zaman | Dr. Mohammad Sarwar Khan | Dr. Khalid Pervaiz | Dr. Shakil | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1994Dissertation note: One hundred milk samples from mastitic buffaloes brought for treatment to outdoor Ward of the College of Veterinary Sciences, Lahore and adjacent areas were examined for their total blood protein, total blood leukocytic count, blood differential leukocytic count, milk whey protein, milk total leukocytic count and milk differential leukocytic count. Total protein, total leukocyte count, neutrophils, lymphocytes, monocytes, eosinophils and basophils in blood gave their average as 6.84 gm/100ml, 4036 cells/mi, 48.17%, 48.32%, 2.34%, 0.69% and 0.48% respectively. Total whey protein, total leukocytic count, neutrophils, lymphocytes, monocytes, eosinophils and basophils in milk showed their average values as 1.02 gm/l00ml, 4665000 cells/mi 70.42%, 24.19%, 3.45%, 1.30% and 0.37% respectively. Correlation between blood and milk protein, total leukocytic count, neutrophils, lymphocytes, monocytes, eosinophils and basophils were estimated as -0.929, 0.962, 0.952, 0.985, -0.203, 0.060 and 0.284 respectively, which gave an increase of total whey protein, neutrophils in blood, neutrophils in milk and milk total leukocyte count and decrease of total blood protein, total blood leukocytes and lymphocytes in milk and blood. Availability: Items available for loan: UVAS Library [Call number: 0406,T] (1).

7. Effect Of Hydatid Cyst On Different Blood Components In Camels Of Different Age Groups

by Hameed ur Rehman | Dr. Muhammad Sarwar Khan | Dr. Khalid Pervaiz | Dr. Shakil | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1995Dissertation note: The present project was designed to find out the prevalence of hydatidosis in different age groups of camels and to see its effect on some blood parameters (TEC, Hb, PCV) and also to examined the same blood parameters of control groups. For this purpose study was carried out on 300 camels of various age groups (2-3 years, 3-5 years, and above 5 years) brought to Lahore abattoir for slaughtering purposes during the period from July 1994 to September 1994. The results showed that out of 300 camels, 189 (63%) were positive for hydatidosis. It revealed that infection rate was higher in Group-Ill (above 5 years) 70%, than in Group-I (58%) and Group-Il(61%). The study also revealed that the prevalence of hydatidosis was 67.68% in July, 54.9% in August and 66.67% in September The present investigation also showed that a mean of total erythrocyte count was 8.667 million/microliter with range of 6.00 million/microliterto 11.101 million/microliter, Haemoglobin concentration was 10.00 g/100ml with a range of 6.3 g/100 13.1 g/l00ml and mean of packed cell volume was 31.7 with a range of 20.00% to 39.00%. The control blood samples of 189 camels showed mean of total erythrocyte was 9.721 million/microliter ranging from 6.32 million/microliter to 12.92 million/microliter, mean of haemoglobin concentration was 11.5g/100ml with a range of 7.3 g/100ml to 14.4g/100ml and packed cell volume was 33.4% with a range of 22.00% to 40.7% Availability: Items available for loan: UVAS Library [Call number: 0413,T] (1).

8. Effect Of Glucocorticoids Alongwith Antimicrobial Drugs Against Haemorrhagic Septicaemia In Buffalo

by Ramzan, M | Prof.Dr.Muhammad Ashraf | Dr. Khalid Pervaiz | Dr. Muhammad | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1995Dissertation note: Two long acting antibiotic preparations of oxytetracycline and amoxicillin were used in these trials against Haemorrhagic Septicaemia, singly and alongwith a combination of synthetic glucocorticoids (Dexamethasone and prednisolone). Eighty buffalo calves suffering from Haemorrhagic Septicaemia were selected and treated under field conditions. Weighted clinical score was recorded before and after treatment in each case, on the basis of severity of clinical symptoms. Reduction in this score and recovery or death of animal was also noted. It was concluded that amoxicillin was more effective than oxytetracycline and the addition of glucocorticoids reduced the convalescence period and also increased the survival rate. Therefore long acting amoxicillin alongwith Dexamethosone and prednisolone is recommended as the successful therapy for Haemorrhagic septicaemia. Availability: Items available for loan: UVAS Library [Call number: 0420,T] (1).

9. Effect Of Routine Deworming On The Development Of Resistance Against Git Nematodes In Sheep

by Akram, M | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahmad | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1994Dissertation note: In this project the effect of routine deworming on GIT nematodes in sheep was studied with particular reference to the development of drug resistance. Comparison was studied by treating the flocks where routine deworming was practiced with the levamisole and albendazole and where routine deworming was not practiced with any medicine. One twenty sheep positive for GIT nematodes infection were selected. They were divided into six groups A, B, C, D, E and F comprising of 20 animal in each group. Animals of group A, B, C were selected from two different floclwhere routine deworming was practiced with levamisole and albendazole respectively. Animals of group D, E, & F were selected from unregistered private flocl where routine deworming was not practiced. Rectal faecal samples were collected before medication and at the seventh day of medication from all the six groups of sheep to count the eggs per gram of faeces and to count the number of larvae after culture under laboratory conditions. Groups A & D were treated with the levamisole orally at the dosage rate of 7.5 mg/kg. Groups B and E were medicated with albendazole orally at the dosage rate of 5 mg/kg and groups C & F were kept as control and remained untreated. Then the efficacy of levamisole and albendazole in addition to the development of resistance against these anthelmintics was estimated. Experimental study revealed that the levamisole showed 98.73% efficacy in the first timely dewormed flock and no any resistance was recorded whereas, 72.55% efficacy was noticed in the regularly dewormed flock, with a slight resistance. Albendazole had 97.13% efficacy in the first timely dewormed private flock and 61.24% efficacy in the regularly dewormed flock. This shows a strong evidence of resistance in the albendazole treated flock. No side effect were observed in both the groups. Levamisole was found better dewormer with less chances of resistance. However, both drugs can be used safely to achieve control of nematode parasites in sheep. Availability: Items available for loan: UVAS Library [Call number: 0421,T] (1).

10. Efficacy Of Ivermectin And Coumaphos Against Ectoparasites In Cattle And Buffaloes

by Nadeem Haider, Syed | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahmed | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1995Dissertation note: The project was designed to find out the efficacy of ivermectin and Coumaphos against ectoparasites in cattle and buffaloes. Thirty buffaloes infested for ectoparasites were selected for the treatment trials and divided into three groups i.e. Bi, B2 and B3 having ten animals in each group and thirty cattle infested for ectoparasites were selected for the treatment trials and also were divided into Cl, C2 and C3 groups. The comparative acaricidal drug trials were conducted on 20 infested animals against ectoparasites of group BI and Cl having ten animal in each were medicated with Ivermectin (lvomec: MSD) injected once by s/c route at dose rate of 200 pg/kg body weight. Observation were made on 7th and 14th day post-medication. Skin scrapping examination was done. The overall efficacy of invermectin on 7th and 14th day in buffaloes was 40% and 80% and in cattle 50% and 90% respectively. The comparative acaricidal drug trials were conducted on 20 infested animals for ectoparasites of B2 and C2 having ten animals in each were treated with Coumaphos (Asuntol: Bayer) at the dose rate of 30-50 gm/animal. On the 7th and 14th day post medication skin scraping examination was done. The efficacy of Coumaphos on 7th and 14th day in buffaloes was 50%, 50% and in cattle 70%, 70% respectively. Animals were also observed for any side effect of both medicine. No side effects were observed during the period from treatment to last observation in any group i.e. groups BI, Cl and B2, C2 groups. On last observation no spontaneous recovery was noted. In B3 and C3 in untreated and control groups. From the results of present study it is concluded that Ivermectin (Ivomec MSD) is the drug of choice for the treatment of ectoparasites in cattle and buffaloes when it is given at the dose rate of 0.2 mg/kg body weight by subcutaneous injection. Availability: Items available for loan: UVAS Library [Call number: 0422,T] (1).

11. Prevalence And Chemotherapy Of Coccidiosis In Sheep And Goats And Its Effect On Certain Blood Parameters

by Nasir Ali, Faridi | Dr. Muhammad Sarwar Khan | Dr. Khalid Pervaz | Dr. Mubasher | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1995Dissertation note: This project was designed to find out the prevalance and chemotherapy of coccidiosis in sheep and goats and its effect on certain blood parameters like Haemoglobin, TLC, DLC, Glucose,and Total Serum Protein. Two drugs namely suiphadimidine and suiphaqunoxaline were used in this research project. For this purpose 60 animals(i.e sheep and goats) were taken and divided into 3 groups(A,B and C) containing 20 animals each(i.e 10 sheep and 10 goats). Group A was again subdivided into two subgroups Ag & As containing 10 animals each(i.e 10 goats and 10 sheeps) were treated with sulphadimidine.Group B was again subdivided into two subgroups Bg & Bs containing 10 animals each(i.e 10 goats and 10 sheeps) were treated with suiphaquinoxaline. Group C was again subdivided into two subgroups Cg & Cs containing 10 animals each (i.e 10 goats and 10 sheeps) were kept as infected non.medicated control. The efficacy of drugs were determined on the reduction of OPG in faeces. From the results it is find out that the average OPG on zero day of medication in groups i.e Ag,As & Bg,Bs were 75100, 72200, 60800 & 67200 respectively.The average reduction of OPG on 10th day of medication in groups i.e Ag,As & Bg,Bs were 300,340,120 & 280 respectively.The OPG of control groups were increased on the subsequent days. The average Haemoglobin on zero day of medication in groups Ag,As,& Bg,Bs were 6.53,8.02,6. 89 & 7.93 respectively The average Haemoglobin on lOtti day of medication in groups Ag,As,Bg,Ss were 8.628.80, 9.44 & 8.78 respectively.The Haemglobin of the control groups were decreased on subsequent days. Average TLC on zero day of medication in groups Ag,As,Bg,Bs were 16.50 ,16.50 & 15.50,19.50.Average TLC on 10th day of medication in groups Ag,As & Bg,Bs were 14.50,12.90 & 13.60,13.50 respectively.The TLC of control groups were increased on the subsequent days.Average DLC on zero day of medication in groups Ag was 49.40,68.00,7.00 11.10 & 17.50 in group Bg was 51.20 ,70.30,6.90, 12.20 & 19.40 in group As was 50.20,70.20,8.00,12.00 & 18.50 in group Bs was 50.40.71.60,6.10,17.20 & 18.40 .Average DLC on 10th day of medication in groups Ag was 48.40,67.00,7.00 11.10 & 17.50 in group Bg was 50.20 ,69.30,7.10,12.20 & 19.40.ln Group As was 49.40,69.10,8.00,12.00 & 18.50 in group Bs was 49.40,70.60,6.10,17.20,18.40.DLC of the control groups were incresed on the subsequent days. Average Blood Glucose on zero day of medication in groups Ag,As,Bg,Bs were 24.30, 31.30 & 29.30, 35.50 respectively.Average Blood Glucose on 10th day of medication in groups Ag,As,Bg,Bs were 37.00, 42.40, 42.80, 45.00. Blood glucose in control were decreased on the subsequent days. Average Total Serum protein on zero day of medication in groups Ag,As & Bg,Bs were 3.52,4.25,3.93,4.18. Average Total Serum protein on 10 th day of medication in groups Ag,As,Bg,Bs were 4.89,5.56 & 5.43,5.57 respectively.The total serum protein in control groups were decreased on the susequent days. Availability: Items available for loan: UVAS Library [Call number: 0426,T] (1).

12. Effect Of Gonadotrophin Releasing Hormone (Gnrh) On Post Partum Ovarian Activity In Nili Ravi Buffaloes

by Akhlaq Tabassam | Dr. Muhammad Aleem | Dr. Kazim Raza Chohan | Dr. Khalid | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1995Dissertation note: Sixteen pluriparus Nili-Ravi buffaloes at 30-35 days postpartum were used. These buffaloes were randomly divided into 2 groups i.e. viz A and B GnRH treated and control group (n=8). A group received single injection of 200jg GnRH and B group served as control. Blood sample were collected on the days 0 (first day of experiment) 4 and 8 of the experiment. At day 0, 4, 8, 12, 16 and 20 in control and treated groups the average size of follicles were 0.91±0.12 and 1.2±0.28 1.1±0.2 cm, 0.6±0.2 cm and 1.9±0.2, 0.37±0.17cm 1.87±0.3, 1.36±0.27, 1.4±0.24, 1.37±0.22, 1.35±0.24, 1.26±2.0 cm respectively. The average number of follicles in GnRH treated and control buffaloes were 1.5±0.17, 1.62±0.16, 1.5±0.21, 0.62±0.32, 1.5±0.3 and 0.37±0.17, 1.5±0.18, 1.5±0.18, 1.75±0.16, 1.36±0.15, 1.37±0.27, 1.25±0.18 at day 0, 4, 8, 12, 16 and 20 respectively. Two animal from treated group responded to GnRH and showed a rise in serum progesterone concentration 0.81, 3.40, 3.44 and .101, 2.93, 3.00 ng/ml at day 0, 4 and 8 respectively. One animal from control group showed a rise in P4 at day 4 only In GnRH group animal exhibited oestrus during 76.5±6.31 days of postpartum. In control group animal exhibited oestrus at 89.7±7.32 days of postpartum. From the present study it is concluded that GnRH treatment at 35 days postpartum can initiate cyclic ovarian activity, and GnRH can be used for luteinization of large follicle present on the ovary\ reduction in calving interval and postpartum interval to oestrus. Availability: Items available for loan: UVAS Library [Call number: 0441,T] (1).

13. Effects Of Clopidol And Lasalocid (Avatec) (Coccidiostats) On The Immunity Of Broiler Chicks Vaccinated

by Umer Farooq, M | Dr. Syed Ata-ur-Rehman Rizvi | Dr. Khalid | Dr. Muhammad Akram Munir | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1994Dissertation note: The birds that received Avatec at recommended dosage levels had higher body weight than the Clopidol medicated, Cyclophosphamide treated or untreated control birds. Both Avatec and Clopidol treatments did not adversely affect the weights of bursa of Fabricius, spleen, thymus and liver of birds. Cyclophosphamide treatment of birds in early life resulted in.bursal atrophy and slight depression of splenic weight gain. Avatec and Clopidol were immuno-stimulants and birds eating medicated rations had higher antibody titres as compared to control birds. The NDV vaccinated birds on Avatec and Clopidol medicated rations and those on non-medicated rations resisted challenge with a virulent ND virus, while the non-vaccinated birds of any treatment group and vaccine free control could not withstand this challenge. Conclusions This study indicated that Clopidol and Avatec, when used at recommended dosage levels (25 gm of Premix/50 kg of feed and 6.25 gm of pure drugl5O kg of feed respectively) did not interfere with the development of birds; did not have any adverse effects on weights of lymphoid organs such as bursa of Fabricius, spleen, thymus, liver; did not interfere with the development of humoral immunity in vaccinated birds. Their medication in feed rather produced beneficial effects on serum, weight gain and antibody production. The injection of Cyclophosphamide resulted in lower body weights, destruction of the bursa of Fabricius, poor antibody response of birds to vaccination against NDV, and very high post-challenge mortality. The weight gain studies indicated that vaccinated and non- vaccinated birds on Clopidol and Avatec medicated feeds had non- significantly higher body weights that those on non-medicated ration at 56 days of age. Avatec at recommended dosage level, had more beneficial effects on the body weights than the Clopidol. These studies further indicated that vaccinated birds kept on Avatec medicated feed had significantly higher serum antibody titres on day 56 than the vaccinated non-medicated control birds. From the results of this study it is concluded that Avatec and Clopidol are not immuno-suppressive drugs when used at recommended dosage levels. They rather have beneficial effects on growth performance and immune response of birds. However, there is a need for further investigations. Availability: Items available for loan: UVAS Library [Call number: 0459,T] (1).

14. Efficacy Of Various Ionophorous Antibiotics Against Coccidiosis In Quails

by Riaz Ahmad Khan | Dr. Khalid Pervez | Dr. Haji Ahmad | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1994Dissertation note: Two hundred and fifty, day old quail chicks were pruchased from a local hatchery and reared up to three weeks of age under hygienic conditions. After three weeks of age, quails were divided randomly into five groups. Group A was kept as control, group B as infected non treated, group C as monensin treated, group D as salinomycin treated and group E as suiphaquinoxalim treated. After three weeks of age, groups B, C, D, and E were infected orally with mixed infection of avian Eimeria species, while group A was kept as control. Signs and symptoms of coccidiosis apperared after six days of infection. After apperarance of signs and symptoms the birds of group C and D were treated with monensin and salinomycin and group E treated with sulphaquinoxaline. The effect of medication on feed consumption, weight gain, feed conversion ratio, mortality, oocyst count and dressing percentage were recorded weekly upto 6 weeks of age. There was significant difference (P<O.05) of feed intake between group B, C, D and E. Maximum feed intake was in group A, followed by group E, C, D, and B, respectively. Weight gain was maximum of group A followed by group E, C, D, and B respectively. The feed conversion ratio (FCR) of control group A, was better than all other groups while feed conversion ratio of group B (infected nontreated) was poor than all other groups. Oocysts count was zero on six days post of medication in group C, (monensin treated) while it was zero after eight days of treatment in group D (salinomycin treated) and oocyst count was zero after four days of medication in group E (suiphaquinoxaline treated). Oocyst count was 32.000 oocystlgm faeces in group B (infected nontreated) after 42 days of age. While it remained zero through out the experiment in control group (group A). Mortality was maximum (10%) in group B (infected non trearted) followed by in group D (4%) and group C, and group E (2%) respectively. While mortality remained zero in group A (control). Dressing percentage was better in group A (62.02%) followed by group E (59.2 1%), group C (58.45%) respectively. Observing the effects of sulphaquinoxaline monensin and salinomycin on feed intake, weight gain, feed conversion ratio, mortality, oocysts count and dressing percentage in experimentally infected (coccidiosis) quails, it was concluded that sulphaquinoxaline has comparatively better results than monensin and salinomycin. Availability: Items available for loan: UVAS Library [Call number: 0468,T] (1).

15. Effect Of Fascioliasis On The Blood Picture And Comparative Efficacy Of Different Fasciolicidal Drugs In Sheep

by Shazia Maqbool | Dr. Khalid Pervaiz | Dr. Mubasher | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1995Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0471,T] (1).

16. A Study Of Changes In Blood Electrolytes And Pcv In Equine Colic

by Mazhar Ayaz, M | Dr. Khalid Pervaz | Dr. Muhammad Sarwar Khan | Dr. Shakil | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1995Dissertation note: Besides mechanized transportation horses have still global importance not only for the communication but it is thought as symbol of superiority in many countries of the world. Horses are confronted with colic once in their life span that some times results in uncompareable loss to the owner. Only a timely and accurate diagnosis is the beacon of hope to save the life. To study the effects of colic on PCV and Blood Electrolytes, twenty horses suffering from colic were taken into investigation to asses the site and type of colic, while ten normal horses were kept as control. Diseased horses were divided into three groups A, B & C mild, moderate and severe respectively. Physical signs of group A were of mild nature comprising swishing of the tail, looking at the flank and lying down for the short periods, while group B showed moderate pain like lying down but not violently and increased bouts of pain. Animals in group C exhibited signs of severe pain by showing severe depression, restlessness, patchy sweating, struggling violently and kicking at the belly due to sharp continuous pain. The heart rate, respiration and rectal temperature in all groups was increased. Rectal palpation was performed in all groups to determine the site of the disease. Changes found in blood electrolytes like Na+, K+, C1- and HCO3 were measured by flame photometry. Group A, B and C showed decrease in Na+, and HCO3 concentration in serum while concentration of K and C1 in serum were normal in all groups. PCV was measured by Wintrobe micro-haematocrit method in all groups. Group A and C showed normal PCV but it was lower in group B. These all observations showed that the animals of group A were suffering from impaction of ileacaecal valve. Pain was not so severe nature that may cause death in colic cases while the animals in group B were showing signs of spasmodic colic. The abnormalities were not so severe to threat the life of the animal but were elevated than the normal. Group C was considerably serious that might lead to death if unattended because the variations and findings were similar with obstruction of small intestine. The serum electrolytes in this group were increased than the other two groups alongwith the elevated respiration, heart rate and rectal temperature that were helping in assessing the condition of the animal. PCV was the reliable tool to know the degree of dehydration in the severe cases. Rectal palpation helped in differentiating the various segments of the intestines involved and the severity of the disease in the diseased animals. Availability: Items available for loan: UVAS Library [Call number: 0472,T] (1).

17. Helminthiasis: Its Dissemination And Treatment With Fenbendazole In The Migrating Sparrows

by Ali Razmaara, Syed | Dr. Muhammad Athar Khan | Dr. Haji Ahmad | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Nature of contents: biography; Literary form: Publisher: 1995Dissertation note: The present study was conducted to bust upon the worm load in the naturally parasitized migratory sparrows, and also to determine the effect of worm load on the blood picture. Furthemore the effect of broad spectrum anthelmintic like Panacur (fenbendazole) in the experimental group in terms of eggs per gm. of faeces pre and post medication. For this experiment 400 live migratory sparrows were purchased randomly, out of which 200 birds were slaughtered and an incidence of 64.5% parasitic fauna was found. Sparrows were found infected, with two species of nematode i.e. Ascaridia gaul was 39.5% and Heterakis gallinarum was 25% respectively. None of the bird was found infected with trematode and cestode. The hematology of the above 64.5% parasitized sparrows was performed. The study revealed that due to nematode infection there was a slight increase in Total leucocytic count and Heterophils whereas the Total erythrocytic count, Haernoglobin level, Lymphocytes and Eosinophils were decreased which may lead to anemia, loss of growth and production. From the left 200 wild naturally parasitized sparrows, 86 (43%) birds were found positive. These sparrows were divided into two groups one was left as control and the other group was subjected to drug efficacy. Panacur (fenbendazole) at the rate of 9.9 mg/kg body weight which was given orally. The results were observed in terms of eggs per gm. of faeces pre and post medication after 24, 48 and 96 hours respectively. The control group showed progressive increase in ova count i.e. 12.82%, 24.79% and 48.72% respectively, whereas reduction in the ova count of the medicated group was gradually observed as 83.72%, 92.25% and 95.35%. The poultry breeders and scientists are urged to make an effort how the wild birds could mechanically transmit the parasites from one region to another. An attempt should also be made for the better understanding of bacterial and viral infections dissemination. Availability: Items available for loan: UVAS Library [Call number: 0474,T] (1).

18. A Serological And Coprological Study Of Paramphistomiasis In Buffalo

by Jameel Ahmad | Dr. Khalid Pervaiz | Dr. Haji Ahmed | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1997Dissertation note: Two hundred faecal samples, serum samples and paramphistomes used in the present study collected from main slaughter house of Lahore and from surrounding of the city. Faecal examinations were carried out with fresh smear technique and 61.5% animals found positive for paramphistomiasis. Serum was separated from the blood samples collected from infected and suspected buffaloes for the performance of enzyme-linked immunosorbent assay. Paramphistome crude antigen was prepared from fresh stomach flukes, which contained 95.66 mg proteins/mi at 545 nm. For performing the enzyme linked immunosorbent assay, the 96 well ELISA plates were coated with crude antigen & kept overnight & then the other procedure for the assay was followed, & the serum samples were tested with paramphistome crude antigen. In positive samples, the yellowish-brown colouration was formed. In faecal examination, 61.5% and in the ELISA 100% of the animal found positive. From the conclusion of the results if was found that ELISA (100%) has given more positive results then faecal examination (61.5%). Availability: Items available for loan: UVAS Library [Call number: 0490,T] (1).

19. Comparative Efficacy On Newly Introduced Antibacterial Drugs Against Experimentally Induced Escherichia Coli

by Zubair, M | Dr. Khalid Pervaiz | Dr. Mubasher | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1996Dissertation note: Pakistan faces an acute shortage of animal protein which is acknowledged as a serious problem at national level. Since broilers are the fastest converters of crude protein into digestible high quality protein for human consumption. There is much need in the production of broilers for the said reason in Pakistan. The upgrading of poultry industry is suffered from huge losses caused by certain diseases of bacterial origin. Amongst bacterial diseases, Escherichia coli is the worst threat to poultry industry. Therefore, concrete and consistent effort was done in this project to control the Eschericia coli infection. The present project was done to study the efficacy of different drugs on prevalent strains of E. coli isolated from broilers that were collected from Diagnostic Laboratory, office of the Project Director, Poultry Production, 16-Cooper Road, Lahore and various Farms in the vicinity of Lahore. Six different antibacterial drugs which comprised of avitryl, advocin, plasmacolin, flumequine gentamicin and inoxyl were used to check the sensitivity of the isolates. In-vitro the sensitivity results was in this order avitryl, advocin, plasmacolin, gentamicin, flumeuine and inoxyl respectively. Avitryl emerged as best drug. The pathogenicity of the isolated strains was tested in albino mice taken from V.R.I., Lahore. The confirmed pathogenic isolates of . coli were diluted upto 3x108 bacteria per 0.25 ml, this dilution ws made after doing total viable count and the dose was injected intra-peritoneally to five albino mice while 5 albino mice were kept as controls. These six drugs were further tested for their efficiency in broilers against . coli infection. A total of two hundred and forty birds reared upto four weeks of age and then they were divided into eight groups, A, B, C, D, E, F, G and H, each having 30 birds. Group H was kept as non-infected and non- treated. While Group G was infected but not treated. The remaining groups A, B, C, D, E and F, 16 hours after infection were treated with avitryl, advocin, plasmacolin, flumequine, gentamicin and inoxyl for five days respectively. All the groups were kept under close observation and their mortality and feed efficiency was noted. In group G maximum mortality was noted i.e. 57.14 while in the group A, B, C, D, E and F, the mortality recorded was 22.72, 30, 33.33, 40.90, 47.82 and 52.17 respectively. Avitryl was proved to be the highest protection against coli infection and best in relation to F.C.R. by this experiment. Availability: Items available for loan: UVAS Library [Call number: 0492,T] (1).

20. A Clinico Pathological Examination And Treatment Of Experimentally Induced Salmonella Infection In Goats

by Baig Muhammad Kakar | Dr. Khalid Pervaiz | Dr. Khushi | Dr. Mohammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1997Dissertation note: Salmonellosis is common problem for goat population of the country which is therefore, a constant threat for the farming community of the country during the summer season. The present study was undertaken to study the course of disease with relevance uo environmental factors and the efficacy of various antirnlcroblal drugs available in the market. Salmonellosis was clinically manifested by acute enteritis, dysentery, abdominal cramps, where as temperature, respiration rate and pulse rate were raised upto 2- 3.4°F, 16-23 times/minute and 10-16 times/minute respectively. Predominant postmortem lesions were dehydration, petechiation of the intestinal mucosa occasionally with the accumulation of reddish fluid in t1e intestinal lumen, thickening of the urinary bladder and Pale carcase along with decreased serum sodium concentration in such animals. Among the various antimicrobial drugs used invitro, Gentamycin and chloraphenicol were highly sensitive where as Oxytectracycline, trimethoprim apicillin and kananycin were quite sensitive. Results of in vivo traits for oxytetracycline, tribrissen, gentamycin were 0.00%, 80%, 80% and 100% respectively, whereas 100% mortality was recorded in untreated control group of animals. Availability: Items available for loan: UVAS Library [Call number: 0494,T] (1).

21. Efficacy Of Three Different Drugs Against Ectoparasites In Naturally Infested Dogs And Their Effect On Blood Parameters

by Sharoon Sabir | Prof.Dr.Muhammad Ashraf | Dr. Khalid Pervaiz | Dr. Mubsher | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1996Dissertation note: The present study was designed to evaluate and compare different drugs in 40 naturally infested dogs (based on skin scrapping examination) taken from Dog Hospital, College of Veterinary Sciences, Lahore and different Pet Clinics. Ivomec, Neguvon and Sulphur Tar Oil were used in three groups while one was control group. Treatment in each group was repeated after 14 days. Blood parameters i.e. Hemoglobin Estimation (Hb), Packed Cell Volume (PCV), Total Erythrocytic Count (TEC) and Total Leucocytic Count (TLC) were estimated. Results of treatment were evaluated on 14 days and 21 days after the first treatment on basis of skin scrapping examination and improvement in clinical symptoms. Efficacy of ivermectin, trichiorophon and sulphur tar oil was 80%, 70% and 40% on 14th day after 1st treatment. Same results were observed one week after second treatment indicating no additional benefit.Based on these observations it was concluded that ivermectin (200 µg/kg, s/c) was safe to use and its efficacy was significantly higher than Neguvon and Sulphurate oil. Moreover a single injection is sufficient for mild cases of ectoparasites but in severe cases second injection may be repeated after 14 days interval. Availability: Items available for loan: UVAS Library [Call number: 0508,T] (1).

22. Anthelmintic Efficacy Of Caesalpinia Crista, Fumaria Parviflora, Mebendazole And Ivermectin Against Haemonchus

by Saeed Ahmad | Prof.Dr.Muhammad Ashraf | Dr. Khalid Pervez, CMS (25n) | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1997Dissertation note: This study was conducted to evaluate the anthelmintic efficacy of Caesalpinia crista, Eumaria parviflora, Mebendazole and Ivermectin against Haemonchus ntortus in sheep. Anthelmintic efficacy of Casesalpinia crista at the dose level of 4 gm/kg body weight was 86.85%, Furneria parvifl at the dose level of 4 gm/kg body weight was 85.32%, Mebendazole at the dose level of 15 mg/kg body weight was 98.05% and Ivermectin at the dose level of 200 jig/kg body weight was 96.55%. There was marked decrease in EPG in all the four groups A, B, C and D treated with . crista, . p.ryjflora, Ivermectin and Mebendazole respectively, whereas an increased value of EPG was observed in group E (unmedicated control) in response to the increasing intensity of infection in sheep. Haematological study of infected animals revealed a considerable increase in Neutrophils, Monocytes, Basophils and Eosinophils while a considerable decrease in Lymphocytes, Total leukocytic count and Total serum proteins was observed. Availability: Items available for loan: UVAS Library [Call number: 0518,T] (1).

23. Prevalence Of Puff Disease In Horses With Biochemical And Chemotherapeutic Studies

by Shamoon ur Rashid | Dr. Muhammad Sarwar Khan | Dr. Javed | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1997Dissertation note: This project was designed to find out the prevalence of puff disease in horses in Lahore area. This study also included chemotherapeutic effect of two different treatments and biochemical studies. This study was conducted during the month of July-September, 1996 at Outdoor Hospital, College of Veterinary Sciences, Lahore and around the city of Lahore. For the prevalence of puff disease 290 horses were examined and their clinical signs were observed. Investigation showed that the occurrence of puff disease in horses was 12.14% i.e. 36 horses out of 290 were found positive. Thirty positive cases were treated with two different groups of treatments. With 1st group of treatment 5 horses were cured completely and with 2nd group of treatment 11 horses were cured completely. The results of treatment were based on the reversal of clinical signs. Serum samples of positive horses were also observed before and after treatment for the detection of glucose, cholesterol and chloride levels. Availability: Items available for loan: UVAS Library [Call number: 0536,T] (1).

24. A Clinico Epidemiiological Study Of Bacterial And Parasitic Causes Of Respiratory Syndrome In Sheep And Goats

by Waseem Shahzad | Dr. Khalid Pervaiz | Dr. Khushi | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1997Dissertation note: In Pakistan sheep and goats production is playing a very important role in bridging the protein gap among our population. Sheep and goats not only provide us high quality meat for our consumption but also wool fibre and high quality leather. In Pakistan every year there is lot of mortality due to respiratory tract infections in sheep and goats especially due to pneumonia which results from a variety of causes' namely, bacterial, viral, parasitic, mycoplasmal and fungal etc. It causes high economic losses due to increased rate of mortality. This study was carried out on two hundred sheep and goats of either sex including all age groups brought to out door hospital of College of Veterinary Sciences, Lahore during February 1997 to June 1997. In the present study isolation and identification of bacterial and parasitic etiological agents of the respiratory tract problems in sheep and goats was carried out. According to this study many bacterial agents causes respiratory problems in sheep and goats, out of 132 positive nasal samples Pasteurella multocida was isolated from 32 (24%), . haemolytica 43 (33%), Corynebacterium 26 (20%), 23 (17%), Streptococcus 18 (14%) and Escherichia ççjj 20 (15%) from affected sheep and goats. Similarly many lungworms cause respiratory problems, out of 82 positive faecal samples Dictvocaulus filaria was isolated from 76 (92.6%) and Protostrongvlus rufesence 6 (7.3%) from affected sheep and goats. The haematological study of the infected and non infected animal showed that there were decreased values of total erythrocytic count, packed cell volume and differential leucocytic count and increased values of total leucocytic count and erythrocytic sedimentation rate of affected animals. Availability: Items available for loan: UVAS Library [Call number: 0539,T] (1).

25. Comparative Efficacy Of Oxyclozanide, Rafoxanide And Bithionol Sulphoxide Against Paramphistomiasis In Buffaloes

by Umar, M | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahmad | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1998Dissertation note: The present project was designed to test the anthelmintic efficacy of oxyclozanide, Rafoxanide and Bithionol suiphoxide against paramph istomiasis in naturally infected buffaloes. The comparative anthelmintic trials were conducted among Nilzan drench - Id (Oxyclozanide 3.0% + Levamisole 1.5%,), Fasifree - Prix (Rafoxanide 30 mg/mI), Irchasol - Medivet (Bithionol sulphoxide 10% + Levamisole 1.5%) and Nilverm drench - ICI (Levamisole 1.5%) against paramphistomiasis in buffaloes. Seventy five naturally infected buffaloes were selected and divided into five equal groups i.e. A, B, C, D and E containing 15 animals each. Each animal of group A was given Nilzan drench (lml/2kg body weight), group B was given Fasifree (lml/4kg body weight), group C was given Irchasol (lml/2kg body weight), group D was given Nilverm (lml/2kg body weight), while group E was kept as control. The efficacy of anthelmintics was evaluated by counting eggs per gram (EPG) of faeces on day 7, 14 and 21 post-medication. The mean efficacyh of Nilzan drench was 97.29%, mean efficacy of Fasifree was 98.5% and of Irchasol was 85.56% while Nilverm did not have any effect for the treatment of Paramphistomiasis in buffaloes under field conditions. Availability: Items available for loan: UVAS Library [Call number: 0547,T] (1).

26. A Clinicopathological Study Of Lactic Acidosis In Sheep And Goats

by Usman, M | Dr. Khalid Pervez | Dr. Javed | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1998Dissertation note: A total of 100 sheep and goats suffering from lactic acidosis brought to Outdoor hospital, College of Veterinary Sciences, Lahore were selected as experimental animals while the same number was kept as control to access the events of lactic acidosis. The temperature, pulse rate, respiration rate, rumen and serum p11, serum bicarbonate, packed cell volume, ruminal movements and ruminal protozoa of the two groups were studied. It was found that rectal temperature, blood pH, rumen p11, serum bicarbonate and ruminal movements decreased significantly in acidotic group as compared to control group. Simultaneously the pulse rate, respiration rate and packed cell volume increased, significantly in lactic acidotic group as compared to control group. Mean values observed in goat were serum pH 7.075±0.11 rumen p11, 4±0.57 serum bicarbonate, 12.42±0.59 mEq/liter, packed cell volume 67.50±3.2%, temperature 100.9±0.19°F, pulse rate 168.6±3.77 per minute and respiration rate 17.00±0.82 and in sheep mean values were 7.025±0.85, 4±0.57, 12.42±0.66 rnEq/liter, 64.25±0.21%, 100.9±0.82 °F, 168.6±3.77 per minute and 17.00±0.82 per minute respectively. The rumen protozoa was found to be completely destroyed in the experimental group. There was complete ruminal stasis in lactic acidotic group. Availability: Items available for loan: UVAS Library [Call number: 0550,T] (1).

27. Comparative Efficacy Of Three Newly Introduced Drugs For The Control Of Experimentally Induced Coccidiosis In Broiler Chicks

by Aslam, M | Dr. M. Sarwar Khan | dr. Kamran | Dr. Khalid Pervaz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1998Dissertation note: One hundred and fifty brioler chicks reared under standars and managmental conditions, were divided into five groups A, B, C, D and E each comprising 30 birds at the ag of 21 days. From 22nd day to onward group A, B and C were given feed mixed with coccidiostats i.e. diclazuril (200mg/kg of feed), maduramicin ammonium 500mg/kg of feed) and salinomycin (1gm/kg of feed) respectively till the end of experiment while group D and E were fed with usual feed. On 28th day, the group A, B, C and D were infected with 75000, sporulated occyst/bird while gropu E was non-infected non-medicated control. Clinical signs were observed only in group B, C and D. The total oocyst count in all groups on zero day of infection was zero. On 1st, 4th and 8th day after the appearance of clinical symptoms, the total oocyst count in group A, B, C and D were 2500, 4900, 9700 and 209600 respectively, while group E examined nil being control non-infected group. Morbidity observed in group B, C and D was 3.33% 16.66% and 83.33% respectively while in group A and E morbidity was not observed. Mortality was observed only in groups C and D that was 3.33% and 30% respectively. The feed intake and feed conversion ratio of group A, B and C was almost equal, while of group D (infected and non-medicated) is concerned it showed better result. Postmortem examination revealed severe enteritis an hemorrhagic lesions in small intestines and caeca, while on histopathology, damage to the absorptive tissue and destructions of the intestinal villi alongwith the merozoites, schizonts and gametocytes in the mucosa and sub-mucosal region of intestine and caeca were observed. The study showed the prophylactic efficacy of diclazuril, maduramicin ammonium and salinomycin in descending ordre respectively. Diclazuril was to be the drug of choic against coccidiosis. Availability: Items available for loan: UVAS Library [Call number: 0561,T] (1).

28. Prevalence And Chemotherapy Of Cestode Infection In Wild Felidae

by Zahid Zia | Dr. Khalid Pervaz | Dr. M. Akram | Dr. M. Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1998Dissertation note: The present wok was conducted to see the efficacy of Niclosamide (Yomesan), Mebendazole (Vermox) and Praziquantel (Droncit) against cestode infection in wild felids in captivity because zoological gardens are permanent source of parastic infestation A survey was conduced to estimate ethe prevalence of various specises of cestodes in 40 wild fields kept in Lahore Zoo and Luch Irani Circus. The prevalence rate was recorded for Lahore Zoo 42.86% and for Lucky Irani Circus 100%. Overall prevalence was estimated (60%). The prevalence rate of Dipylidium caninum, Echinococcus/Taenia species, Spriometra felis and Joyeuxiella pasaquaeli was recroded 32.60, 55.33, 39.81 and 27.90 percent, respectively. The animals showing moderat to heavy infection were selected for therapeutic trails. Two trainls were conducted wild felids kept in the Lahore Zoo and Luch Irani Circus comprising 12 animals each. In both experimental station four groups i.e. A, B, C and D of animals were made. Group A, B and C wre treated with Niclosamide (Yomesan)Mebendazole (Vermox) and Praziquantle (Droncit) respectively, while group D was kept as untreated control group. The efficacy of the drug was detrmined on the basis of reduction in the number of ova and segments discharged in the faeces on 7th, 14th, 21st and 28th day of post medication. Results revealed that Praziquantel (Droncit) was the drug of choice against all species of cestodes, as it was found highly effective throughout the experiment. Membendazole (Vermox) was also found 100% effective against different species of cestodes upto 14th day of the experiment. Niclosamide (Yomesan) was not found as effective as other two drugs. Availability: Items available for loan: UVAS Library [Call number: 0567,T] (1).

29. Prevalence Of Mixed Infection Of Nematodes And Trematodes In Camels At Lahore And Their Effect On Blood Picture

by Asif, M | Dr. M. Sarwar Khan | Dr. Khalid Pervaiz | Dr. M. Afzal | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1998Dissertation note: The present project was designed to know the prevalence of mixed infection of Nematodes and Trematodes in camels at Lahore and the effect of this condition on different blood parameters. The source of camels was Lahore Abattoir. A total of 200 camels were examined from June 1998 to September 1998. Fecal samples were taken from the camels and at the same time blood samples were also taken from the same camel. Fecal samples were examined at Central Diagnostic Laboratory. Medicine Section, and College of Veterinary Sciences Lahore. Fecal samples were examined by the direct smear examination and salt floatation method. Camels were divided into four groups, group A. camels positive for any nematode, liver fluke and paramphistome, group B. camels positive for liver fluke and nématode, group C. camels positive for paramphistome and nematode and an other group D was comprised of camels declared negative I or above mentioned helminthes. The blood samples of only those camels were subjected for examination, which were declared positive for any of the three groups. The prevalence of group A camels was 2.5% and highest prevalence of these camels was observed in the months of June and September. The prevalence of group B was 8 %. and of group C was 3 %. The overall prevalence of nematodes and treniatocles was 70 0o. Only 30 % camels were free of these helminthes. I3lood examination conducted for group A revealed increased Total leukocyte count average was 44000/cubic mm. and range was 40000-48000/cubic nun. Average T.E.C was 3.9 M/cubic mm. and Hh. 11 gm!dl., range for T.E.C 3.6- 4.3 M/cubic mm and I-lb.. was 9-l3gm/dl. D.L.C revealed average neutrophils 75%, lymphocytes 25% and range in neutrophils was 73-77% and lymphocytes were 23-27%. Blood examination conducted for group B revealed increased Total leukocyte count average was 38000/cubic mm. and range was 33000-42000/cubic mm. Average T.E.C was 4.4 M/cubic mm. and Hb. 11.2 grnldl.. range for T.E.C 4- 4.8 M/cubic mm and I-lb. was 8-l3gm/di. D.LC revealed average neutrophils 70%, lymphocytes 28% and range in neutrophils was 68-73% and lymphocytes were 26-30% average monocytes were 2.1% and range was l-S%. Blood examination conducted for group C revealed increased Total leukocyte count average was 35000/cubic mm. and range was 28000-39000/cubic mm. Average for T.E.C 4 M/cubic mm. and Hb. 10.5 gm/dl.. range for T.E.C 3.8-4.5 M/cubic mm and Hh., was 8.8-1 1.7 gm/dl. D.L.C' revealed average neutrophils 75%, lymphocytes 24.6% and range in neutrophils was 74-77% and lymphocytes were 23-26% average range of monocyte was 0.3%, 0-1% respectively. Blood examination conducted for group D revealed increased Total leukocyte count average was 156000/cubic mm. and range was 13900-20000/cubic mm. Average for T.E.C 5.27 M/cuhic mm. and fIb. 14.6 gm/dl., range for T.E.C 4.9-5.6 M/cubic mm and Fib., was 12-l6gm/di. D.L.C revealed average neutrophils 6.8%, lymphocytes 28.4% and range in neutrophils was 65-72% and lymphocytes were 25-3O% for monocytes and eosinophil average was 1.8%, 0.8% and range was 0-3°/o,0-25 respectively. Availability: Items available for loan: UVAS Library [Call number: 0572,T] (1).

30. Incidence Of Molluscan Intermediate Host And Faecal Diagnosis Of Bovine Schistosomiasis In And Around Lahore

by Naeem Irshad | Dr. Haji Ahmad Hashmi | Dr. Kamran Ashraf | Dr. Khalid | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1998Dissertation note: An investigation was undertaken to find out the prevalence of molluscan intermediate host, identification of the infected and non infected snails harbouring the intermediate stages of Schistosoma bovis and the role of coprological examination in the diagnosis of bovine schistosomiasis. Four places in and around Lahore were selected for the purpose of collection of snails, isolation of cercariae from these snails and collection of faecal samples for coprological examination Four hundred snails were collected, 100 from each of 3 ponds and a natural habitat. The Snails were collected fortnightly from October 1997 to December 1997. Prevalence of Lymneae acuminate, L. luteola, Indoplanorbis exustus, Physa acuta Melania tuberculata and Gyralaus was found to be 37.75%, 3.25%, 58%, 20.83%, 1.92% and 1.33%, respectively. Only Indoplanobis exustus was infected with intermediate stage of schistosomes, i.e. C. nudifurca and C. indice with total infection of 12792 (C nudifurca) and 7930 (C.indice) in Bansinager fish pond and Mustafabad drain Kahana, Distt. Lahore during the period from October, 1997 to December, 1997. Out of total 200 faecal samples, 32% were positive for Schistosoma infection with 3 species of genus. The positive cases showed S. bovis (100%), S. Japonicum (75%) and S. nasalis (7.8%). Availability: Items available for loan: UVAS Library [Call number: 0593,T] (1).

31. Epidemiology And Economic Losses Of Trichostrongylid Parasites In Sheep

by Sarwar Khan, M | Dr. Muhammad Athar Khan | Dr. Haji Ahmad | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1997Dissertation note: The meteorological data recorded during the study period from 1.1.96 to 31.12.96 showed the maximum temperature in June as 36.5°C and minimum temperature in December as 6.8°C. Maximum and minimum Humidity was recorded in the month of September and April as 85% and 55% respectively. The maximum rainfall during the year was recorded in the month of August as 660 mm. The faecal egg counts of sheep grazing on permanent pasture showed the minimum EPG during first week of January while maximum EPG on nid of September and first week of October. Pasture larval counts were performed on permanent pasture and experimental plot for the recovery of trichostrongylid larvae. The maximum number of larvae was recovered on 16th September, 1996, while minimum number was recovered in January and February from permanent pasture and experimental plot respectively. Two species of trichostrongylids were identified i.e. Haemonchus contortus and Trichostrongvlus colubriformis. The faecal and larval counts were very low in the months of January and February, the counts started rising in March. Peak counts were seen in the month of September. Decline in counts started in late October and reached to minimum in December. Mature and immature worm counts of slaughtered sheep were performed at 15 days interval. The, overall prevalence oftrichostrongylid parasites was 34%. The maximum number of mature parasites were seen during first week of October which was886 whereas maximum number of immature parasites including hypobiotic was 326 on 1st of December. During this study the average fecundity/female of contortus and L colubriformis parasites were calculated as 721 and 209 respectively. A spring rise in worm egg counts was experienced in mid of March. A pen parturient rise in the worm egg counts of pregnant and lactating ewes indicated the maximum counts during lambing week. An experimental group of sheep with mixed infection of trichostrongylid parasites showed the similar pattern of EPG counts as of naturally infected sheep. A study was performed to evaluate any protection provided by a particular Flaemoglobin type to trichostrongylid infection hut not difference could be observed. The Asparate Aminotransferase (AST) and total protein levels of infected sheep were decreased as a result of increase in the intensity of infection. A decrease in R.B.C. counts, Haemoglobin, Packed cell volume and lymphocyte counts was observed both in experimentally and naturally infected slaughtered sheep. However, an increase in total leukocytic count (TLC) alongwith an increase in the ratio of neutrophils, eosinophils and basophils was observed. At the end of experiment infected sheep gained 5.71 Kg/head less body weight and produced 4 3 grn less wool as compared with non-infected group. Based on epidemiological information the suggestions for control of the, trichostrongylid infection are submitted alongwi th recommendations for further studies. Availability: Items available for loan: UVAS Library [Call number: 0595,T] (1).

32. Treatment Of Experimentally Induced Coccidiosis And Its Effect On Various Blood Components In Quails

by Hameed, A | Dr. M. Sarwar Khan | Dr. Asif | Dr. Khalid Pervez | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1999Dissertation note: This project was designed to study the effect of experimentally induced coccidiosis on some blood parameters and its treatment with Amprolium 20% and Suiphadimidine alone and with Vitamin A and Vitamin K supplementation in quails. For this purpose one hundred and eighty (180) quails of two weeks old were obtained and reared controlled coccidia free conditions and provided coccidiostat free feed. At the age of 3 weeks birds were divided into 6 groups (i.e. A, B, C, D, E and F) comprising 30 birds in each groups. Group-A: Infected and medicated with Amprolium. Group-B: Infected and medicated with Sulphadimidine sodium. Group-C: Infected and medicated with Amprolium and Vitamins A&K. Group-D: Infected and medicated with Suiphadimidine sodium and Vitamins A&K. Group-E: Infected and non medicated. Group-F: Non infected non-medicated (Control). The clinical symptoms were more pronounced in those birds which were treated with Suiphadimidine and Amprolium without any supplementation of Vitamins A and K. The mortality rate lower and OPG was nil at 12th day of medication in the group which was treated with Amprolium and Vitamins A&K supplementation than the other groups. Feed conversion ratio (FCR) and average weight gain of the birds was significantly improved by the addition of Vitamins A and K supplementation with Sulphadimidine and Amprolium than of the birds which were medicated without any vitamin supplementation. The average FCR of those groups which were medicated without vitamin supplementation and with vitamin supplementation were calculated as 3.9, 4.2, 3.7 and 3.9, respectively. Haemoglobin estimation was also improved in the groups which were treated with the supplementation of vitamin A and vitamin K. And highest haemoglobin value was estimated in group C (9.8 gm/100 ml at 12th day of medication), which was medicated with Amprolium and vitamin A and vitamin K supplementation. The study showed efficacy of Amproliurn and Suiphadimidine with Supplementation for vitamins A and K in descending order. Amprolium with supplementation of vitamins A and K was proved to be best drug against coccidiosis in quails. Availability: Items available for loan: UVAS Library [Call number: 0598,T] (1).

33. Comparative Efficacy Of Various Drugs Used Against Naturally Infected Horsed With Babesiosis

by Mamoona Ali | Dr. Khalid Pervez | Dr. Asif | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1999Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0600,T] (1).

34. Comparative Sensitivity Of Agpt, Iha & Elisa In Determing The Antibody Response Against Ibd Virus Using Intermediate Plus (Hot) Strain 228E and Bur706

by Asim, M | Dr . Muhammad Naeem | Dr . Khalid | Dr . Muhammad Akram Munir | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1999Dissertation note: The present project was aimed at determining the comparative sensitivity of AGPT, IHA and ELISA. By determining the maternal antibody titre against IBDV. The protective efficacy of vaccines 228-E, BUR-706 and Gumboral CT was also evaluated by challenging the vaccinated birds with virulent IBD virus. A total of 200 day-old birds were randomly divided into four equal groups designated A, B, C and D. Chicks of group A, B and C were vaccinated with 228-F, BUR-706 and Gumboral CT, respectively. Group B served as un-vaccinated control. ELISA was found more sensitive than AGPT and IHA in determining maternal antibody titre. Higher antibody titres were produced by 228-F compared to BUR-706 and Gumboral CT, respectively. Maximum mean ELISA titres in group A, B, C and D on day 35 were 10,080, 8539, 7022 and 537, respectively. Decline in maternal antibody titre was observed weekly. AGPT could detect it up to day 14, while IHA up to day 2] and ELISA up to day 35. 228-F [Intermediate Hot (Plus) strain] provided maximum protection in vaccinated birds when challenged on day 20 and day 35 post-vaccination. Availability: Items available for loan: UVAS Library [Call number: 0675,T] (1).

35. Passive Immuniation Of Newcastle Disease Virus Infected Birds

by Raheel Arshad | Dr . Khushi Muhammad | Dr . Khalid | Dr . Sa meera Akhtar | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2000Dissertation note: Present study was designed to determine the contribution of maternal immunity against the Newcastle disease (ND). In the study two hundred and ten white leghorn cockerels were used. A velogenic ND virus field isolate was used for the challenge. Lethal Dose 50 (LD5O) of the velogenic strain of ND virus was calculated which was 10.727. Maternal antibody levels of the chicks were determined on weekly basis by using the haemaggldtination inhibition (HI) test. The maternal geometric mean HI titre recorded at 1, 7, 14, 21 and 28 days of the age of birds were 147, 157.6, 22.6, 13 and 2.6 respectively. The protection offered by maternal immunity in chicks challenged with 100 LD50 at 1, 7, 14, 21 and 28 days of age was, 100, 100, 70, 10 and 0 percent respectively. It was concluded that birds having maternal hurnoral immunity more than 64 GMT showed 100% protection to challenge infection. The effect of immunized egg yolk to ND infected birds was also studied. The HI titre of immunized yolk was determined and then different HI units of the immunized yolk were prepared with normal saline. It was observed that egg yolk (1 ml, 64 HI units) injected to ND challenged birds showed 100% protection as compared to that of control group (given 1 ml of 0 HI units of the yolk). The cost of the production of immunized yolk was also determined that was Rs.0.35 / dose (1 ml : 64 HI units). From the study, it was inferred that the hyper immunized yolk can be used as therapeutic agent to cure the ND infected birds. Availability: Items available for loan: UVAS Library [Call number: 0679,T] (1).

36. Passive Immunization Of Infectious Bursal Disease Infected Broiler Chicks

by Fazli Rabbi | Dr . Khushi Muhammad | Dr . Khalid | Dr . Muhammad Akram Munir | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 2000Dissertation note: Infectious bursal disease (IBD) is a common problem in commercial unvaccinated birds and causing heavy economical losses to the poultry industry. Chicken layers when primed with oil based 113D vaccine at age of 13 weeks and boosted with the same vaccine at 15 weeks of age showed high titre of yolk agar gel precipitating (AGPT) antibodies against IBD virus when tested on 21 and 28 weeks of age. Storage temperature (+4°C and -20°C) had undetectable effects on the physical properties (color and smell) and AGPT titres of the hyperimmunized yolk contnining 0.5% forrnalin (v/v). r[he AGPT antibody titre of the hyperimmunized yolk had good correlation with the enzyme linked immunosorbant assay (ELTSA) titre of 113D virus antibodies (r: 0.92). The IBD infected broilers (28 days old) when passively immunized with the yolk (one ml: 64 AGPT units of IBD antibody titre) induced 80% recovery as compared to that of untreated (control) birds. It is anticipated that the hyperimmunized yolk may he used as a therapeutic agent to cure the IBD infected birds. Availability: Items available for loan: UVAS Library [Call number: 0687,T] (1).

37. Comparative Efficacy Of The Latest Antibacterial Drugs Against Experimentally Induced Pullorum Disease

by Dr . Khalid Omran, M | Dr . Khalid Pervaiz | Dr . Khushi | Dr . Mohammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1997Dissertation note: A total 210 birds were reared upto the age of 4 weeks and the divided into 7 groups viz A, B, C, D, E, F and G, comprised of 30 birds in each group. At the age of 28 days the groups A to E were experimentally infected with Salmonella pullorum inoculation intraperitoneally with the dose rate of '/2 ml. The group F was infected but non-medicated and the group G was kept as control (non infected and non medicated). The groups A, B, C, D, E and E were treated with Anflox, Inoxyl, Triquine, Flumiquine and Gentamycine respectively. All the groups were kept under close observation to record clinical signs, mortality rate, weight gain and feed conversion ratio. Postmortem of dead birds was also conducted. The blood parameters TEC, TLC, and DLC were also estimated post medication on 1st, 3rd and 5th day. The mortality before medication in groups A, B, C, D, E and F was 10%, 16.67, 6.67%, 13.34%, 13.34% and 6.67% respectively. While the mortality during treatment in each group was 25.92%, 32%, 39.28%, 19.23%, 46.16%, 64.28% respectively. The mortality in control group was 6.66% during these days. According to this trial Flumiquine provided maximum protection against Salmonella pullorum infection and proved best in relation to weight gain and FCR. Anflox stood second in the list while Inoxyl was the 3rd drug which provided protection against the infection, whereas Triquine and Gentamycin were the least effective drugs. The signs which appeared after 18-24 hours post infection were listlessness, ruffled feathers, droopy wings, loss of appetite, poor growth, depression, increased thirst and severe diarrhoea of chalky white color. The post mortem findings were enlarged spleen, congested liver with streaked haemorrhages, congested and distended kidneys, grey hepatization in lungs and enlarged heart. The total erythrocytic count decreased in infected non-medicated birds while in medicated groups it remained in normal range. The same was true of total leucocytic count. However, in DLC the heterophil indicated increased percentage after inoculation of infection while the lymphocytes, basophils, eosinophils and monocytes remained within range after the infection. The findings of the present study elucidate the disease and help in diagnosis and treatment of this malady. Availability: Items available for loan: UVAS Library [Call number: 0688,T] (1).

38. Epidemiological Studies On The Prevalence Of Coccidiosis In Commercial Broilers And Its Relationship With Other Diseases

by Umber Rauf | Dr . Asif Rabbani | Dr . Khalid Saeed | Dr. Shakil | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1999Dissertation note: In this epidemiological study 26.48% birds of 26.82% farms were found affected with coccidiosis. Six species of Eimeria, E. acervulina. E. mitis, E. tenella, E. necatrix, E. praecox and E. mivati were observed. Number of oocysts in litter varied with the age of birds. Concurrent infections were detected in 80.68% cases, which included infectious coryza 21.95%, aflatoxicosis 27.45%, infectious bursal disease 16.94%, chronic respiratory disease 12.54%, Newcastle disease 10.16%, hydropericardium syndrome 9.83%, Escherichia coli 9.15% and Salmonella 8.13% infections. In the month of July and August , incidence of coccidiosis was high. Maximum incidence of disease was observed from 4th to 6th week while no disease incidence was noted during 1st and 8th week. It was also noted that the disease had drastic effects on Newcastle disease antibody titer. Availability: Items available for loan: UVAS Library [Call number: 0691,T] (1).

39. Serological Investigations Into Caprine Brucellosis

by Zulfiqar Ahmad | Dr . Khalid Pervez | Dr . Mubashar | Dr . Muhammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1985Dissertation note: In the present study an attempt was made to measure the incidence of brucellosis in goats. A total number of five hundred blood samples were collected from animals including 237 males and 263 females, belonging to various age groups, different sources and different breeds. The clear serum was separated and subjected to microscopic slide agglutination test and serum tube agglutination test. On the basis of microscopic slide agglutination test 5.2% goats were found positive for brucellosis. By serum tube agglutination test the percentage of positive cases was 1.2%. A total number of 159 milk samples from the individual animals were subjected to milk ring test. Of these samples 5.03% were found positive for the disease. A comparison amongst the methods used for diagnosis of brucellosis indicated that serum tube agglutination test was the most reliable test for diagnosis of caprine brucellosis. Anyhow, the other two test can be used for screening under field condition. The overall incidence of caprine brucellosis recorded in this study was 1.2% Availability: Items available for loan: UVAS Library [Call number: 0702,T] (1).

40. Prevalence And Chemotherapy Of Namatode Infestation In Sheep

by Ghulam Murtaza | Dr . Lftikhar Gul Ahmad | Dr . Khalid | Dr . Khizar Hayat | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2001Dissertation note: The present project was designed to find out the prevalence of nematodes and to evaluate the comparative efficacy of Albendazole, Levamisole and Oxfedazole against naturally occurring gastrointestinal nematodes in sheep under field conditions in and around Bhakkar city. For this purpose the faecal samples of two hundred sheep were processed through coprological examination. Out of 200 sheep, 127 were found positive, so the prevalence of nematode was 63.5%. Out of positive animals 40 were randomly divided into four groups (10 sheep in each group). Group A: Albendazole (Albazole, Nawan Lab.) was given at dose rate of 5 mg/kg body weight. Group B: Levamisole (Nilverm, ICI) was given at dose rate of 7.5 mg/kg body weight. Group C: Oxfendazole (Oxafax, Glaxowelicome) was given at dose rate of 4.5 mg/kg body weight, while group D was kept as positive control non-medicated. The efficacy of anthelmintics was evaluated on the basis of reduction of eggs per gram (EPG) of faeces on 7th, 14th and 21st day post-medication. Efficacy of Albendazole (Albazole) was 96.33%, 97.61% and 98.89% on 7th, 14th and 21st day, respectively. Efficacy of Levamisole (Nilverm) was 99.26%, 100% and 100% on 7th, 14th and 21st day, respectively. Efficacy of Oxfendazole (Oxafax) was 98.39%, 99.46% and 99.82% on 7th, 14th and 21st day, respectively. It was concluded from the above results that Levarnisole (Nilverm) was more effective than Albendazole (Albazole) or Oxfendazole (Oxafax). However, Oxfendazole showed better efficacy than that of Albendazole. Availability: Items available for loan: UVAS Library [Call number: 0710,T] (1).

41. Effects Of Lincomycin And Spectinomycin Combination On The Immune Response Of Newcastle Disease Virus Vacinated

by Rahat Munir Chaudhry | Dr. Shakil Akhtar Khan | Dr. Asim Aslam | Dr. Khalid Saeed | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2002Dissertation note: The project was designed to observe the effects of Lincospectin on the immune system of broiler chicks. Chicks divided in groups A, B and C were offered Lincospectin at 225mg/kg; 450mg/kg and 112.5 mg/kg body weight levels, respectively. All the chicks in various treatment groups were reared upto day 42 and the effects of Lincospectin on organ body weight indices, gross lesions on liver, spleen, thyrnus and bursa of Fabricius, and immune response of chicks against Newcastle Disease Virus vaccination, were determined. The organ body weight indices of spleen, thymus and bursa of Fabricius and liver did not indicate significant differences (P>0.05) amongst the Lincospectin treated and untreated groups. However, the bursal body weight ratio of chicks in groups A, B and C at day 7 were significantly higher than those of group D. The data obtained on the analysis of HI antibody titre against Newcastle Disease Virus on days 1,7,14, 21, 28, 35 and 42 indicated that the geometric mean HI titres of Lincospectin treated groups (A, B and C) were quite different from each other and the chicks of group A had the best sero conversion. It was concluded that over all group A had the best immune response against NDV vaccination. This study indicates that Lincospectin at a dose rate of 225mg/kg body weight did not interfere in the immune response of chicks to NDV, helped in better wiehgt gains upto day 42 and did not cause any gross or histopathological lesions in the organs like thymus, bursa of Fabricius, spleen or liver. Availability: Items available for loan: UVAS Library [Call number: 0756,T] (1).

42. Effect Of Exposure Of Organophosphate Insecticide (Trichlorfon) On The Health Status Andweight Gain In Broiler Chicks

by Misbah Zulfiqar | Dr. Muhammad Sarwar Khan | Dr. Khalid Pervez | Dr. Muhammad | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2002Dissertation note: The investigation was conducted to study the effects of organophos)hate insecticide Trichlorft)n (Nawagon) on heal Lii status, weight gain in broiler chicks and to see the elTicacy ol atropinc sulphate against this problem. Seventy five day old broiler chicks were reared upto 3 weeks of age under proper managemental conditions. At the end of 2nd week they were randomly divided into 5 groups i.e. A, 13, C, D and E containing 15 chicks in each group. Group A was maintained on a Iced containing Nawagon at dose rate of 20mg/kg in feed. Group B was maintained on a feed containing Nawagon at dose rate of 50mg/kg in feed . Group C was maintained on feed containing Nawagon at dose rate of 100mg/kg in feed. Group D was maintained on feed containing Nawagon at dose rate of 200mg/kg in feed. Group E was kept as control. A-Il the groups were maintained on this feed for 7 clays. The weights of birds from each group were taken bebore treatment with Nawagon. The symptoms were recorded thrmighout the experiment and observed (hat during 4th week fteci intake of all the treated groups was decreased, growth was retarded significantly. Group A and B showed no symptoms. There were 3 mortalities in group C. The postmortem findings were small haemolThages throughout the body muscles liepatoinegaly, spleenomegaly, enlarged heart, swollen kidneys. All other birds of group C showed dyspnea, tremor exhaustion, in coordination and dropping of wings. There were no mortalities in group D but birds showed dyspnea, tremors, exhaustion, in coordination, ataxia, dropping of wings and paralysis of legs. So some birds were disable to walk at the end of 4111 week. During 5th week the birds of group C and D were treated with atropine sulphate. At the end of 3rd or 4th day of' 5 week. The birds were normal. Feed intake and growth was normal. Legs were normal. At the end of 6th week all the birds of treated group showed normal behaviour when compared with the control group. No clinical signs were observed in liver, heart, spleen and kidneys of group E (control). Availability: Items available for loan: UVAS Library [Call number: 0768,T] (1).

43. Prevalence And Chemotherapy Of Ascariasis In Cross-Bred Calves In And Around Lahore

by Waqar Ahmad | Dr. Muhammad Sarwar Khan | Dr. Khalid Pervaiz | Dr. Muhamad | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 2002Dissertation note: The present project was designed to find out the prevalence of ascariasis in cross-bred calves in and around Lahore and to evaluate anthelmiiitic efficacy of albendazole, oxfendazole and fumaria parviflora against ascariasis. For this purpose the faeces of 203 cross-bred calves under 3 months aged from various localities in and adjoining city of Lahore were examined for the presence of ascariasis. Forty calves were found positive. It was observed that the prevalence of ascariasis was 19.62%. Forty naturally infected calves having moderate to heavy infection were divided into 4 groups A, B, C and D, each having 10 calves. Ten calves were acted as non-infected and non-medicated (control) as group E. The anthelmintic efficacy of albendazole, oxfendazole and fumaria parviflora was studied by administering to group A, B and C respectively. The efficacy of the drug was determined on the basis of reduction in number of ova count, present in the faeces after medication. Anthelmintic efficacy of albendazole (@ 5mg/kg body weight), oxfendazole (@ 4.5mg/kg body weight) and fumaria parviflora (@ 2gm/kg body weight) was observed to be 83.67%, 95.09% and 0% at clay 5 respectively and at 10 days 99.65%, 100% and 20.15% respectively. It was found that systamex was the most effective drug for the treatment of ascariasis in crossbred calves. Second was the albenclazole. None of these drugs produced any side effects. Availability: Items available for loan: UVAS Library [Call number: 0770,T] (1).

44. Imunization Of Rabbits Against Boophilus Microplus Using Midgut And Salivary Glands

by Mohammad Asif | Dr. Khalid Saeed | Dr. H. A. Hashmi | Dr. Khushi | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2002Dissertation note: The current research was conducted as a simulation model in rabbits for the development of vaccines against cattle ticks Boophilus micro/us using tick salivary glands & midgut as the sources of antigens. The comparative efficacy of these vaccines was evaluated on the basis of antibody titres and tick rejection on the host in terms of mortality, decrease in egg laying and decrease in hatchability of eggs. It was found that the vaccine prepared from the midgut of B. microplus gave better results than the vaccine prepared from salivary glands. The highest percentage of dead ticks was observed in animals which were given midgut vaccine (21.82%). This vaccine also caused a significant decrease in the egg laying capacity of the ticks (35.83%). However, none of the vaccines had any significant effect on the hatchability of eggs laid by the ticks. The highest antibody titers were observed in rabbits injected with midgut vaccine (GMT=5.50), which was 45.28% higher than rabbits given salivary gland vaccine. The overall success rate for midgut vaccine, in terms of tick mortality on host, decrease in egg laying capacity and antibody titer,. was 37.06% for midgut vaccine while only 16.51% for salivary gland vaccine. The results are very encouraging and it is hoped that with the original host i.e. cattle, more satisfactory results can be achieved. Availability: Items available for loan: UVAS Library [Call number: 0771,T] (1).

45. Effect Of Different Routes Of Vaccination Against Newcastle Disease On Lymphoid Organs Of Broilers

by Rabia Salam | Dr. Asim Aslam | Dr. Khalid | Dr. Shakil Akhtar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 2002Dissertation note: This project was designed to compare two routes (intraocular and drinking water) of vaccination against Newcastle disease in terms of protection against velogenic field isolate of NDV by noting immune response and morphological changes in Harderian gland, Bursa of Fabricius and thymus of broilers. This project would also help to evaluate role of Harderian gland to generate local and humoral immunity in response to eye drop and drinking water vaccination against NDV. For this purpose, a total of 160 day-old chicks were procured from local commercial hatchery. At day 7 birds were randomly divided into four groups i.e. A, B, C, D comprising 40 birds each. Group A and B were vaccinated through ocular and oral route respectively. While groups C and D were kept as control. At day 21, groups A and B were revaccinated through the same routes. At day 28, groups A, B and C were further sub-divided into two subgroups each i.e. Al and A2, Bi and B2, Cl and C2, respectively. Subgroups Al, Bl and Cl were challenged, ocularly while subgroups A2, B2 and C2 were challenged orally with velogenic field isolate of NDV. Ocular vaccination resulted in higher level of circulating antibodies and increased number of plasma cells in Harderian gland. It can be inferred that ocular vaccination stimulated Harderian gland to produce strong lcal protective immunity both in ocular and oral mucosa. Availability: Items available for loan: UVAS Library [Call number: 0774,T] (1).

46. The Effect Of Experimentally Induced Yolk Sac Infection With Staphylococcus Aureus On Immune Status Of Broiler Chicks

by Dr. Shakil Akhtar Khan | Dr. Asim Aslam | Dr. Khalid Saeed | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2002Dissertation note: The present project was carried out to study the effect of experimentally induced yolk sac infection with Staphylococcus aureus on immune status of broiler chicks. For this purpose one hundred day-old chicks were procured from local market and were randomly divided into two groups, A and B having fifty chicks each. Confirmed pathogenic isolate of Staphylococcus aureus was inoculated into the yolk of each chick of group A while group B acted as control. Ten chicks from each group were slaughtered at interval of 48 hours i.e. on 3rd 5th 7th, and 9th day of the experiment and serum and yolk were collected. Experimental parameters included pathological examination of yolk sac, yolk sac weight/body weight ratio, antibody titres against Newcastle disease virus (NDV) in serum and yolk and analysis of fractional serum proteins. Results showed that yolk sac weight/body weight ratio was higher in treatment group than in control group. Marked pathological changes (abnormal colour, consistency and odour) were also observed in unabsorbed yolks of the infected group. Geometric mean titres of maternal antibodies against NDV were significantly lower in serum while higher in yolk of the infected group as compared to control one. Sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) was used for serum protein analysis and percent area covered by each protein fraction was calculated. The percent area covered by most fractions of serum protein was lower in infected chicks than the control chicks. It is therefore concluded that experimental yolk sac infection with Saphylococcus aureus leads to decreased maternal antibodies absorption from infected yolks and altered serum proteins indicating decline in the immunity of the chicks. Availability: Items available for loan: UVAS Library [Call number: 0786,T] (1).

47. Prevalence And Chemotherapy Of Nematodes Infestation In Wild And Dometic Pigeons And Its Effects On Various Blood Components

by Tauqeer Basit, M | Dr. Khalid Pervez, Prof.CMS | Dr. Muhammad Sarwar Khan, Associate | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 2003Dissertation note: Apparently healthy one hundred wild and one hundred domestic pigeons were purchased from the local market which were kept for a period of thirty days under observation. They were subjected to coprological examination for the presence of nematode eggs. One group of forty naturally infested wild pigeons and other group of forty domestic pigeons were selected. They were infested with Ascaridha columba, Capillaria obsginata and Ascaridia gjj one or more type of nematodes. All the forty domestic pigeons as well as forty wild pigeons were divided into eight groups comprising of ten pigeons each. Among the domestic pigeons three groups i.e. D1, D2 and D3 were treated with Ivermectin, Oxfendazole and Piperazine respectively while the fourth group i.e. CD was titled as an un-treated control group. Similarly the three groups i.e. WI, W2 and W3 of wild pigeons were treated with Ivermectin, Oxfendazole and Piperazine respectively while the fourth group i.e. CW was kept as controlled untreated group. Egg per gram was done on day zero, tenth and twenty first day of experiment. On zero day of experiment after taking the fecal samples Ivermectin, Oxfendazole and Piperazine were administered in DI and WI, D2 and W2, D3 and W3 groups of pigeons respectively. The efficacy rate of Oxfendazole, Ivermectin and Piperazine in the domestic pigeons was 60%, 100% & 80% respectively while the efficacy percentage for wild pigeons was 50%, 100% and 80% with the treatment of Oxfendazole, Ivermectin and Piperazine. The Ivermectin treated group showed the best results in term of lowest EPG st day post treatment and hemoglobin estimation was maximum i.e. 10.8mg/dI in DI and WI as compared to control group. Similarly TLC was minimum i.e. 0.2million Ofl 21st day of the experiment in the lvermectin treated group of domestic pigeons. Availability: Items available for loan: UVAS Library [Call number: 0794,T] (1).

48. Comparative Efficacy Of Various Drugs Against Gastrodiscus In Horses

by Wasim Ahmad Malik | Dr. Khalid Pervez, Prof.CMS | Dr.Muhammad Sarwar Khan | Mr. Kamran | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2003Dissertation note: This study was conducted to work out the prevalence of gastrodiscus infection in Lahore district and to check the efficacy of three different drugs i.e. Oxfendazole, Albendazole and Ivermectin againstastrodiscus infection in horses. This disease is cosmopolitan in distribution. Five hundred faecal samples of horses were collected and coprological examined by fresh smear method to determine 30 naturally infected horses by Qastrodiscus infection. These animals were divided into three groups i.e. group A, group B and group C. Each group was comprising of 10 animals. Groups A, B and C were treated with Oxfendazole, Albendazole and Ivermectin, respectively. The prevalence of gastrodiscus infection at Lahore area o.nd out to be 6%. The eggs per gram (EPG) counts was estimated using MacMaster technique at zero day (pre-medication), 3rd day, 7th day and 14th day (post-medication). Groups A, B and C were treated with Oxfendazole, Albendazole and Ivermectin at companies recommended dose rate of 1.2 ml/2 kg body weight, 1 ml/13 kg body weight and 1.0 ml/50 kg body weight, respectively. After medication at 3rd, 7th and 14th day EPG count was measured. It was observed that at 3rd day Oxfendazole, Albendazole and Ivermectin showed the efficacy 51.36%, 60.52% and 17.5%, respectively. At 7th day the efficacy of Oxfendazole, Albendazole and Ivermectin was found to be 58.18%, 72.63% and 7.5%, respectively. At 14th day the efficacy of Oxfendazole, Albendazole and Ivermectin was found to be 59.09%, 75.26% and 3.5%, respectively. The average efficacy of Oxfendazole, Albendazole and Ivermectin was found to be 56.21%, 69.47% and 9.5%, respectively. Hence Oxfendazole and Abendazole showed better results as compared to Ivermectin. It was concluded Oxfendazole and Albendazole were safe against Gastrodiscus in horses. Availability: Items available for loan: UVAS Library [Call number: 0795,T] (1).

49. Chemotherapeutical And Hematological Studies Of Experimentally Induced Cocidiosis In Pigeons

by Rashid Ghaffar | Dr. Khalid Pervez | Dr. Kamran | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 2004Dissertation note: This project was designed for the Chemotherapeutical and Haematological studies of induced coccidiosis in pigeons. For this purpose three anticocidials were used. These were ancoban (Amprolium), Supercoc (Sulphaquinoxaline) and Phytocox (Herbal Product). These were used alone and with the addition of vitamin A and K. Some Haematological Studies were also done i.e. total Leucocytic Count (TLC), differential leucocytic count (DLC) and Haemoglobin (Hb) estimation. One hundred and twenty healthy young pigeons were obtained and were provided coccidiosis free feed. These pigeons were divided into eight groups viz; A, B, C, D, E, F, G, and H comprising 15 birds each. 30,000 viable sporulated oocysts were inoculated directly into the crops of pigeons of group A to G. The medication was started on day 4 post-inoculation of oocysts. Group A, B and C were given Ancoban, Supercoc and Phytocox, respectively. Groups D,E and F were given Ancoban, Supercoc and Phytocox (Herbal Product), respectively with the addition of vitamin`A and K. The Group G was infected, untreated control while group H was uninfected, untreated (Healthy) control. The clinical signs were more pronounced in the groups that were treated without the addition of vitamin A and K.The highest efficacy of the drug was found in group E which was 99.36%. Haemoglobin estimation was done on day 0, 4, 9 and day 14. It was concluded that haemoglobin values were decreased after clinical signs had appeared. Total leucocytic count was also done on day 0, 4, 9 and day 14. There was increase in TLC after infection had occurred and started to decrease after day 9. The differential leucocytic count, lymphocytes decreased while heterohils and monocytes were increased and eosinophils and basophils showed variation in their number was compared to control group. The oocyst count was done on day 4, day 9 and day 14 post-inocultion of oocyst. The efficacy of the drug given to the group E was 99.40% which was the best among all the groups. The result of the present study showed that supercoc (sulphaquinoxaline) with addition of vitamin A and K was comparatively better drug for the control and treatment for cocidiosis in pigeons. Availability: Items available for loan: UVAS Library [Call number: 0841,T] (1).

50. Comparative Efficacy Of Screqing And Plating For The Repair Of Mid-Shaft Metacarpal Fracture In Dogs

by Shehla Gul Bokhari | Dr. Muhamad Arif Khan | Dr. Khalid Pervez | Dr. Muhamad | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2004Dissertation note: The present research work was conducted to find the most effective method of internal fixation for the repair of short oblique mid-shaft metacarpal fracture in dogs. For this purpose, 12 mongrel dogs of either sex were selected and randomly divided into three groups, i.e. A, B and C, comprising four animals each. Short oblique third metacarpal fractures were created in either limb with the help of surgical saw, chisel and hammer, under general anesthesia (Pentothal sodium). In Group A, internal fixation was carried out using a miniature finger plate of size: 2.7mm. On the other hand, internal fixation in Group B was achieved by the application of a single cortical bone screw (size: 2.7mm).Group C served as the Control group and in these animals, no method of internal fixation was applied. The post-operative period was monitored by regular clinical evaluation of wound healing, lameness examination of the dogs at walk and trot, respectively, and the radiographic assessment of callus formation after every 15 days' interval. Post-mortem examination of each animal was also conducted at the end of the 12 weeks' experimental period, to check the gross lesions at the fractured site. Finally, the data thus collected was statistically analyzed using One-way Analysis of Variance. The healing of the wound was quite promising in Group A, delayed and complicated in Group B and satisfactory in Group C. Lameness subsided remarkably in Group A, so that after 12 weeks, the dogs returned to their normal gait with a fully functional limb both, at walk, as well as, at trot. However, in Group B, the dogs recovered slowly, with signs of obvious lameness even on termination of the experimental period. Similar findings were observed in the dogs belonging to Group C, which depicted the picture of marked lameness in their gait. Radiographic evaluation carried out for the three groups, showed evidence of ideal bone union with a desired amount of callus formation in Group A, which was not found in dogs of the other two groups. On post-mortem examination, gross lesions were also found to be of superior degree in the plated dogs when compared to the animals in the other groups. Besides this, statistical analysis also revealed that the technique of plating had an edge over those cases which were left untreated. Hence, on the basis of clinical picture, it was concluded that plating was the best suited method for the ideal repair of short oblique metacarpal fractures, especially in those precious breeds of dogs which are kept for athletic and hunting purposes. Availability: Items available for loan: UVAS Library [Call number: 0845,T] (1).



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