1.
Comparative Efficacy Of Various Drugs Against Experimentally Induced Mycoplasmosis In Quails
by Ayaz Issac J.S.Lall | Dr. Khalid Pervez | Dr. Hajid | Dr. Mohammad Athar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1994Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0377,T] (1).
2.
Efficacy Of Various Ionophorous Antibiotics Against Coccidiosis In Quails
by Riaz Ahmad Khan | Dr. Khalid Pervez | Dr. Haji Ahmad | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1994Dissertation note: Two hundred and fifty, day old quail chicks were pruchased from a local hatchery and reared up to three weeks of age under hygienic conditions. After three weeks of age, quails were divided randomly into five groups. Group A was kept as control, group B as infected non treated, group C as monensin treated, group D as salinomycin treated and group E as suiphaquinoxalim treated.
After three weeks of age, groups B, C, D, and E were infected orally with mixed infection of avian Eimeria species, while group A was kept as control. Signs and symptoms of coccidiosis apperared after six days of infection. After apperarance of signs and symptoms the birds of group C and D were treated with monensin and salinomycin and group E treated with sulphaquinoxaline.
The effect of medication on feed consumption, weight gain, feed conversion ratio, mortality, oocyst count and dressing percentage were recorded weekly upto 6 weeks of age. There was significant difference (P<O.05) of feed intake between group B, C, D and E. Maximum feed intake was in group A, followed by group E, C, D, and B, respectively. Weight gain was maximum of group A followed by group E, C, D, and B respectively.
The feed conversion ratio (FCR) of control group A, was better than all other groups while feed conversion ratio of group B (infected nontreated) was poor than all other groups.
Oocysts count was zero on six days post of medication in group C, (monensin treated) while it was zero after eight days of treatment in group D (salinomycin treated) and oocyst count was zero after four days of medication in group E (suiphaquinoxaline treated). Oocyst count was 32.000 oocystlgm faeces in group B (infected nontreated) after 42 days of age. While it remained zero through out the experiment in control group (group A). Mortality was maximum (10%) in group B (infected non trearted) followed by in group D (4%) and group C, and group E (2%) respectively. While mortality remained zero in group A (control). Dressing percentage was better in group A (62.02%) followed by group E (59.2 1%), group C (58.45%) respectively.
Observing the effects of sulphaquinoxaline monensin and salinomycin on feed intake, weight gain, feed conversion ratio, mortality, oocysts count and dressing percentage in experimentally infected (coccidiosis) quails, it was concluded that sulphaquinoxaline has comparatively better results than monensin and salinomycin.
Availability: Items available for loan: UVAS Library [Call number: 0468,T] (1).
3.
Anthelmintic Efficacy Of Caesalpinia Crista, Fumaria Parviflora, Mebendazole And Ivermectin Against Haemonchus
by Saeed Ahmad | Prof.Dr.Muhammad Ashraf | Dr. Khalid Pervez, CMS (25n) | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1997Dissertation note: This study was conducted to evaluate the anthelmintic efficacy of Caesalpinia crista, Eumaria parviflora, Mebendazole and Ivermectin against Haemonchus ntortus in sheep. Anthelmintic efficacy of Casesalpinia crista at the dose level of 4 gm/kg body weight was 86.85%, Furneria parvifl at the dose level of 4 gm/kg body weight was 85.32%, Mebendazole at the dose level of 15 mg/kg body weight was 98.05% and Ivermectin at the dose level of 200 jig/kg body weight was 96.55%. There was marked decrease in EPG in all the four groups A, B, C and D treated with . crista, . p.ryjflora, Ivermectin and Mebendazole respectively, whereas an increased value of EPG was observed in group E (unmedicated control) in response to the increasing intensity of infection in sheep. Haematological study of infected animals revealed a considerable increase in Neutrophils, Monocytes, Basophils and Eosinophils while a considerable decrease in Lymphocytes, Total leukocytic count and Total serum proteins was observed.
Availability: Items available for loan: UVAS Library [Call number: 0518,T] (1).
4.
A Clinicopathological Study Of Lactic Acidosis In Sheep And Goats
by Usman, M | Dr. Khalid Pervez | Dr. Javed | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1998Dissertation note: A total of 100 sheep and goats suffering from lactic acidosis brought to Outdoor hospital, College of Veterinary Sciences, Lahore were selected as experimental animals while the same number was kept as control to access the events of lactic acidosis. The temperature, pulse rate, respiration rate, rumen and serum p11, serum bicarbonate, packed cell volume, ruminal movements and ruminal protozoa of the two groups were studied.
It was found that rectal temperature, blood pH, rumen p11, serum bicarbonate and ruminal movements decreased significantly in acidotic group as compared to control group. Simultaneously the pulse rate, respiration rate and packed cell volume increased, significantly in lactic acidotic group as compared to control group. Mean values observed in goat were serum pH 7.075±0.11 rumen p11, 4±0.57 serum bicarbonate, 12.42±0.59 mEq/liter, packed cell volume 67.50±3.2%, temperature 100.9±0.19°F, pulse rate 168.6±3.77 per minute and respiration rate 17.00±0.82 and in sheep mean values were 7.025±0.85, 4±0.57, 12.42±0.66 rnEq/liter, 64.25±0.21%, 100.9±0.82 °F, 168.6±3.77 per minute and 17.00±0.82 per minute respectively.
The rumen protozoa was found to be completely destroyed in the experimental group. There was complete ruminal stasis in lactic acidotic group.
Availability: Items available for loan: UVAS Library [Call number: 0550,T] (1).
5.
Treatment Of Experimentally Induced Coccidiosis And Its Effect On Various Blood Components In Quails
by Hameed, A | Dr. M. Sarwar Khan | Dr. Asif | Dr. Khalid Pervez | Faculty of Veterinary Sciences.
Material type: ; Format:
print
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not fiction
Publisher: 1999Dissertation note: This project was designed to study the effect of experimentally induced coccidiosis on some blood parameters and its treatment with Amprolium 20% and Suiphadimidine alone and with Vitamin A and Vitamin K supplementation in quails. For this purpose one hundred and eighty (180) quails of two weeks old were obtained and reared controlled coccidia free conditions and provided coccidiostat free feed. At the age of 3 weeks birds were divided into 6 groups (i.e. A, B, C, D, E and F) comprising 30 birds in each groups.
Group-A: Infected and medicated with Amprolium.
Group-B: Infected and medicated with Sulphadimidine sodium.
Group-C: Infected and medicated with Amprolium and Vitamins
A&K.
Group-D: Infected and medicated with Suiphadimidine sodium and Vitamins A&K.
Group-E: Infected and non medicated.
Group-F: Non infected non-medicated (Control).
The clinical symptoms were more pronounced in those birds which were treated with Suiphadimidine and Amprolium without any supplementation of Vitamins A and K.
The mortality rate lower and OPG was nil at 12th day of medication in the group which was treated with Amprolium and Vitamins A&K supplementation than the other groups.
Feed conversion ratio (FCR) and average weight gain of the birds was significantly improved by the addition of Vitamins A and K supplementation with Sulphadimidine and Amprolium than of the birds which were medicated without any vitamin supplementation. The average FCR of those groups which were medicated without vitamin supplementation and with vitamin supplementation were calculated as 3.9, 4.2, 3.7 and 3.9, respectively.
Haemoglobin estimation was also improved in the groups which were treated with the supplementation of vitamin A and vitamin K. And highest haemoglobin value was estimated in group C (9.8 gm/100 ml at 12th day of medication), which was medicated with Amprolium and vitamin A and vitamin K supplementation.
The study showed efficacy of Amproliurn and Suiphadimidine with Supplementation for vitamins A and K in descending order. Amprolium with supplementation of vitamins A and K was proved to be best drug against coccidiosis in quails.
Availability: Items available for loan: UVAS Library [Call number: 0598,T] (1).
6.
Comparative Efficacy Of Various Drugs Used Against Naturally Infected Horsed With Babesiosis
by Mamoona Ali | Dr. Khalid Pervez | Dr. Asif | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1999Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0600,T] (1).
7.
Serological Investigations Into Caprine Brucellosis
by Zulfiqar Ahmad | Dr . Khalid Pervez | Dr . Mubashar | Dr . Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1985Dissertation note: In the present study an attempt was made to measure the incidence of brucellosis in goats. A total number of five hundred blood samples were collected from animals including 237 males and 263 females, belonging to various age groups, different sources and different breeds. The clear serum was separated and subjected to microscopic slide agglutination test and serum tube agglutination test. On the basis of microscopic slide agglutination test 5.2% goats were found positive for brucellosis. By serum tube agglutination test the percentage of positive cases was 1.2%. A total number of 159 milk samples from the individual animals were subjected to milk ring test. Of these samples 5.03% were found positive for the disease.
A comparison amongst the methods used for diagnosis of brucellosis indicated that serum tube agglutination test was the most reliable test for diagnosis of caprine brucellosis. Anyhow, the other two test can be used for screening under field condition. The overall incidence of caprine brucellosis recorded in this study was 1.2%
Availability: Items available for loan: UVAS Library [Call number: 0702,T] (1).
8.
Effect Of Exposure Of Organophosphate Insecticide (Trichlorfon) On The Health Status Andweight Gain In Broiler Chicks
by Misbah Zulfiqar | Dr. Muhammad Sarwar Khan | Dr. Khalid Pervez | Dr. Muhammad | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2002Dissertation note: The investigation was conducted to study the effects of organophos)hate insecticide Trichlorft)n (Nawagon) on heal Lii status, weight gain in broiler chicks and to see the elTicacy ol atropinc sulphate against this problem. Seventy five day old broiler chicks were reared upto 3 weeks of age under proper managemental conditions. At the end of 2nd week they were randomly divided into 5 groups i.e. A, 13, C, D and E containing 15 chicks in each group. Group A was maintained on a Iced containing Nawagon at dose rate of 20mg/kg in feed. Group B was maintained on a feed containing Nawagon at dose rate of 50mg/kg in feed . Group C was maintained on feed containing Nawagon at dose rate of 100mg/kg in feed. Group D was maintained on feed containing Nawagon at dose rate of 200mg/kg in feed. Group E was kept as control. A-Il the groups were maintained on this feed for 7 clays. The weights of birds from each group were taken bebore treatment with Nawagon.
The symptoms were recorded thrmighout the experiment and observed (hat during 4th week fteci intake of all the treated groups was decreased, growth was retarded significantly. Group A and B showed no symptoms. There were 3 mortalities in group C. The postmortem findings were small haemolThages throughout the body muscles liepatoinegaly, spleenomegaly, enlarged heart, swollen kidneys. All other birds of group C showed dyspnea, tremor exhaustion, in coordination and dropping of wings.
There were no mortalities in group D but birds showed dyspnea, tremors, exhaustion, in coordination, ataxia, dropping of wings and paralysis of legs. So some birds were disable to walk at the end of 4111 week.
During 5th week the birds of group C and D were treated with atropine sulphate. At the end of 3rd or 4th day of' 5 week. The birds were normal. Feed intake and growth was normal. Legs were normal. At the end of 6th week all the birds of treated group showed normal behaviour when compared with the control group. No clinical signs were observed in liver, heart, spleen and kidneys of group E (control).
Availability: Items available for loan: UVAS Library [Call number: 0768,T] (1).
9.
Prevalence And Chemotherapy Of Nematodes Infestation In Wild And Dometic Pigeons And Its Effects On Various Blood Components
by Tauqeer Basit, M | Dr. Khalid Pervez, Prof.CMS | Dr. Muhammad Sarwar Khan, Associate | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2003Dissertation note: Apparently healthy one hundred wild and one hundred domestic pigeons were purchased from the local market which were kept for a period of thirty days under observation. They were subjected to coprological examination for the presence of nematode eggs. One group of forty naturally infested wild pigeons and other group of forty domestic pigeons were selected. They were infested with Ascaridha columba, Capillaria obsginata and Ascaridia gjj one or more type of nematodes.
All the forty domestic pigeons as well as forty wild pigeons were divided into eight groups comprising of ten pigeons each. Among the domestic pigeons three groups i.e. D1, D2 and D3 were treated with Ivermectin, Oxfendazole and Piperazine respectively while the fourth group i.e. CD was titled as an un-treated control group. Similarly the three groups i.e. WI, W2 and W3 of wild pigeons were treated with Ivermectin, Oxfendazole and Piperazine respectively while the fourth group i.e. CW was kept as controlled untreated group. Egg per gram was done on day zero, tenth and twenty first day of experiment. On zero day of experiment after taking the fecal samples Ivermectin, Oxfendazole and Piperazine were administered in DI and WI, D2 and W2, D3 and W3 groups of pigeons respectively.
The efficacy rate of Oxfendazole, Ivermectin and Piperazine in the domestic pigeons was 60%, 100% & 80% respectively while the efficacy percentage for wild pigeons was 50%, 100% and 80% with the treatment of Oxfendazole, Ivermectin and Piperazine.
The Ivermectin treated group showed the best results in term of lowest EPG st day post treatment and hemoglobin estimation was maximum i.e. 10.8mg/dI in DI and WI as compared to control group. Similarly TLC was minimum i.e. 0.2million Ofl 21st day of the experiment in the lvermectin treated group of domestic pigeons.
Availability: Items available for loan: UVAS Library [Call number: 0794,T] (1).
10.
Comparative Efficacy Of Various Drugs Against Gastrodiscus In Horses
by Wasim Ahmad Malik | Dr. Khalid Pervez, Prof.CMS | Dr.Muhammad Sarwar Khan | Mr. Kamran | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2003Dissertation note: This study was conducted to work out the prevalence of gastrodiscus infection in Lahore district and to check the efficacy of three different drugs i.e. Oxfendazole, Albendazole and Ivermectin againstastrodiscus infection in horses. This disease is cosmopolitan in distribution.
Five hundred faecal samples of horses were collected and coprological examined by fresh smear method to determine 30 naturally infected horses by Qastrodiscus infection.
These animals were divided into three groups i.e. group A, group B and group C. Each group was comprising of 10 animals. Groups A, B and C were treated with Oxfendazole, Albendazole and Ivermectin, respectively. The prevalence of gastrodiscus infection at Lahore area o.nd out to be 6%. The eggs per gram (EPG) counts was estimated using MacMaster technique at zero day (pre-medication), 3rd day, 7th day and 14th day (post-medication). Groups A, B and C were treated with Oxfendazole, Albendazole and Ivermectin at companies recommended dose rate of 1.2 ml/2 kg body weight, 1 ml/13 kg body weight and 1.0 ml/50 kg body weight, respectively.
After medication at 3rd, 7th and 14th day EPG count was measured. It was observed that at 3rd day Oxfendazole, Albendazole and Ivermectin showed the efficacy 51.36%, 60.52% and 17.5%, respectively.
At 7th day the efficacy of Oxfendazole, Albendazole and Ivermectin was found to be 58.18%, 72.63% and 7.5%, respectively.
At 14th day the efficacy of Oxfendazole, Albendazole and Ivermectin was found to be 59.09%, 75.26% and 3.5%, respectively.
The average efficacy of Oxfendazole, Albendazole and Ivermectin was found to be 56.21%, 69.47% and 9.5%, respectively. Hence Oxfendazole and Abendazole showed better results as compared to Ivermectin. It was concluded Oxfendazole and Albendazole were safe against Gastrodiscus in horses.
Availability: Items available for loan: UVAS Library [Call number: 0795,T] (1).
11.
Chemotherapeutical And Hematological Studies Of Experimentally Induced Cocidiosis In Pigeons
by Rashid Ghaffar | Dr. Khalid Pervez | Dr. Kamran | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2004Dissertation note: This project was designed for the Chemotherapeutical and Haematological studies of induced coccidiosis in pigeons. For this purpose three anticocidials were used. These were ancoban (Amprolium), Supercoc (Sulphaquinoxaline) and Phytocox (Herbal Product). These were used alone and with the addition of vitamin A and K. Some Haematological Studies were also done i.e. total Leucocytic Count (TLC), differential leucocytic count (DLC) and Haemoglobin (Hb) estimation.
One hundred and twenty healthy young pigeons were obtained and were provided coccidiosis free feed. These pigeons were divided into eight groups viz; A, B, C, D, E, F, G, and H comprising 15 birds each. 30,000 viable sporulated oocysts were inoculated directly into the crops of pigeons of group A to G.
The medication was started on day 4 post-inoculation of oocysts. Group A, B and C were given Ancoban, Supercoc and Phytocox, respectively. Groups D,E and F were given Ancoban, Supercoc and Phytocox (Herbal Product), respectively with the addition of vitamin`A and K. The Group G was infected, untreated control while group H was uninfected, untreated (Healthy) control. The clinical signs were more pronounced in the groups that were treated without the addition of vitamin A and K.The highest efficacy of the drug was found in group E which was 99.36%.
Haemoglobin estimation was done on day 0, 4, 9 and day 14. It was concluded that haemoglobin values were decreased after clinical signs had appeared. Total leucocytic count was also done on day 0, 4, 9 and day 14. There was increase in TLC after infection had occurred and started to decrease after day 9. The differential leucocytic count, lymphocytes decreased while heterohils and monocytes were increased and eosinophils and basophils showed variation in their number was compared to control group. The oocyst count was done on day 4, day 9 and day 14 post-inocultion of oocyst. The efficacy of the drug given to the group E was 99.40% which was the best among all the groups.
The result of the present study showed that supercoc (sulphaquinoxaline) with addition of vitamin A and K was comparatively better drug for the control and treatment for cocidiosis in pigeons.
Availability: Items available for loan: UVAS Library [Call number: 0841,T] (1).
12.
Comparative Efficacy Of Screqing And Plating For The Repair Of Mid-Shaft Metacarpal Fracture In Dogs
by Shehla Gul Bokhari | Dr. Muhamad Arif Khan | Dr. Khalid Pervez | Dr. Muhamad | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2004Dissertation note: The present research work was conducted to find the most effective method of internal fixation for the repair of short oblique mid-shaft metacarpal fracture in dogs. For this purpose, 12 mongrel dogs of either sex were selected and randomly divided into three groups, i.e. A, B and C, comprising four animals each. Short oblique third metacarpal fractures were created in either limb with the help of surgical saw, chisel and hammer, under general anesthesia (Pentothal sodium). In Group A, internal fixation was carried out using a miniature finger plate of size: 2.7mm. On the other hand, internal fixation in Group B was achieved by the application of a single cortical bone screw (size: 2.7mm).Group C served as the Control group and in these animals, no method of internal fixation was applied. The post-operative period was monitored by regular clinical evaluation of wound healing, lameness examination of the dogs at walk and trot, respectively, and the radiographic assessment of callus formation after every 15 days' interval. Post-mortem examination of each animal was also conducted at the end of the 12 weeks' experimental period, to check the gross lesions at the fractured site. Finally, the data thus collected was statistically analyzed using One-way Analysis of Variance. The healing of the wound was quite promising in Group A, delayed and complicated in Group B and satisfactory in Group C. Lameness subsided remarkably in Group A, so that after 12 weeks, the dogs returned to their normal gait with a fully functional limb both, at walk, as well as, at trot. However, in Group B, the dogs recovered slowly, with signs of obvious lameness even on termination of the experimental period. Similar findings were observed in the dogs belonging to Group C, which depicted the picture of marked lameness in their gait. Radiographic evaluation carried out for the three groups, showed evidence of ideal bone union with a desired amount of callus formation in Group A, which was not found in dogs of the other two groups. On post-mortem examination, gross lesions were also found to be of superior degree in the plated dogs when compared to the animals in the other groups. Besides this, statistical analysis also revealed that the technique of plating had an edge over those cases which were left untreated. Hence, on the basis of clinical picture, it was concluded that plating was the best suited method for the ideal repair of short oblique metacarpal fractures, especially in those precious breeds of dogs which are kept for athletic and hunting purposes.
Availability: Items available for loan: UVAS Library [Call number: 0845,T] (1).
13.
Prevalence And Treatment Trials Against Gastrodiscus Infestation And Its Effect On Various Blood Components In Horses
by Muhammad Ali | Prof. Dr. khalid pervez | Dr. kamran ashraf | Dr. muhammad | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2005Dissertation note: This study was conducted to work out the prevalence of gastrodiscus infection in Lahore area and to check the comparative efficacy of one patent (Albandazole) and two Herbal Drugs i.e. Melia Azadarch Linn (Neem) and Nigella Sativa (Kalonji) against Gastrodiscus infection in Horses and its effect on various blood components including Hb, TLC, and DLC the purpose of this experiment was tomention extensive Pharmacological Experimentation on indigenous drug which result in the discovery of some potent Anthelmintic Drugs which would be a break through in limiting Gastrodiscus infection in horses. Furthermore, it could contribute to the improvement of our economy by making an industrial use of these resources and by saving foreign exchange via exporting these medicines abroad. In addition to these, studies were expected to contribute to the rationalization of Eastern / Unani system of Medicine, practiced by HKIMS and SIANAS.
To accomplish the study six hundred faecal samples of horses were collected and coprologically examined by fresh smear method to determine 40 naturally infected horses by Gastrodiscus infection.
The 40 infected animals were divided into four groups i.e. group A, group B, group C, and group D comprising 10 animals. Each groups A, B and C were treated with Albandazole, Melia Azadarch Linn (Neem) and Kalonji, respectively were as group D was control and remain untreated. The prevalence of Gastrodiscus infection at Lahore areas was found to be 6.6%.
The Egg per gram (EPG) counts was estimated by using Macmaster technique at zero day (pre-medication), 3rd day, 7th day and 10th day (post-medication). Groups A, B and C were treated with Albandazole, Neem and Kalonji seeds dose rate of 10ml/10kg body weight, 500 mg/kg body weight and 1gm/kg body weight, respectively.
After medication at 3rd, 7th and 10th day EPG count was measured. It was observed that at 3rd day, Albandazole Neem and Kalonji showed the efficacy 50%, 4769% and 9.09% respectively.
At 7th day, the efficacy of albandazole neem and kalonji was found to be 66.66%, 53.84%, 20% respectively.
At 10th day, the efficacy of albandazole Neem and Kalonji was found to be 95%, 60% and 27.27, respectively.
The average efficacy of Albandazole Neem and Kalonji was found to be 70.5%, 53.6% and 18.78%, respectively.
Hence, Albandazole, and Neem showed better results as compared to Kalonji. It was concluded that Albandazole and Neem were safe against Gastrodiscus in Horses.
HAEMATOLOGY
In the present study forty blood samples from naturally infected horses with different intensities of infection were examined for haematological studies to know the changes in the blood picture due to Gastrodiscus. The blood samples were collected premedication i.e. on Zero day and then on 3rd, 7th and 10th day post-medication.
A marked decrease in haemoglobin was observed after the study of infected animals on Zero day. The normal haemoglobin value was 10.5 to 15.5 g/dl. This value became near to normal on 7th day post-medication and went on increasing upto 10th day as the ova count in the faeces was decreasing.
The study regarding the total leukocytic count concluded a mild increase values of TLC, but after treatment these values decrease to normal level as the ova count in the faeces was decreasing.
The haematological finding of the present study are in complete accordance with the results of Chaudhry et al., (1991) and Peal et al. (1989). The reported that there was decrease in hemoglobin values of infected animals as compared to healthy animals. It is tempting to speculate that the decrease in haematological values may be due to the blood sucking habit of the parasite.
Availability: Items available for loan: UVAS Library [Call number: 0851,T] (1).
14.
Clinico-Biochemical Studies On Detomidine Analgesia And Effects Of Its Combinatios On Animals
by Muhammad Arif Khan | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahmad | Dr. Khalid Pervez | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2003Dissertation note: The overall objective of this study was to evaluate the newly introduced imidazole derivative, drug "detomidine" with alpha-2 adr2noceptor binding properties, and its various combinations in animals. A clinico-hiochemical study was carried out to explore the various aspects of a novel sedative and analgesic drug. Analgesia was evaluated by performing castration in small ruminants, rumenal fistulization in large ruminants, skin prick test, electric stimulation, and developing an experimental colic model in donkeys. The parameters used to evaluate analgesia revealed that detomidine has greater potential to lessen the pain during minor and major surgical interventions in different animals. However, its local usage to achieve paravertebral and epidural analgesia proved that detomidine produces general effect after getting into the circulation and very poor local effect. It has been concluded that the drug can be used as preanaesthetic with chloral hydrate and pentothal sodium anaesthesia to perform major surgical exercises in equine and canine respectively. In addition it has an edge over other sedative drugs on account of its undetrimental effect on various physiological parameters of the animals. Clinical trials have proved that detomidine "a novel sedative and analgesic" is a drug of choice for restraining, examination, and minor and major surgical manipulations on equine, bovine, caprine, ovine and canine species without any untoward effects.
Availability: Items available for loan: UVAS Library [Call number: 0867,T] (1).
15.
Prevalence Of Brucellosis In Breeding And Game Horses In Lahore Division
by Syed Muhammad Jaafar Fayyaz | Dr. Khalid Pervez | Dr. Azhar | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2004Dissertation note: Sero-prevalence of brucellosis in 400 breeding and game horses from various sources in Lahore Division was analysed. Two serological tests namely Rose bengal plate and standard tube agglutination tests were employed. The Rose bengal plate test served for initial screening and the sera declared positive by Rose bengal plate test were further analysed through standard tube agglutination test, which served for quantitation of Brucella antibodies. A higher incidence of disease prevalence was recorded through Rose bengal plate test than standard tube agglutination test. The overall prevalence of the disease investigated by Rose bengal plate test was 2.5% and with the standard tube agglutination test was 0.25% in horses. The male horses had a prevalence of 0.74% by the Rose bengal plate test, female horses demonstrated a prevalence of 6.15% by Rose bengal plate test and 0.76% by standard tube agglutination test. The higher prevalence of disease was observed in female horses. While interpreting the age group relationship of the disease. It was found that adult and old animals had a higher prevalence than the young animals. The horses over 10 years of age exhibited 7.95% disease incidence by Rose bengal plate test and 1.13% by standard tube agglutination test. Only 1.54% disease prevalence was investigated in horses below 10 years of age by Rose bengal plate test. Sero prevalence of brucellosis was only detected in horses recruited from Race Cource and Phool Nagar, whereas sera of all the horses belonging to Army, Police, Rangers, Race Club and Aitchison College was negative to brucellosis. It may be due to good management of horses, good nutrition, lack of stress and no contact with cattle. The sera with SAT titre of 1:40, were considered positive while the sera showing titre of 1:20 were declared doubtful. There is need to adopt an eradication programme for brucellosis especially because of its zoonotic importance and a continuous threat to livestock industry in the shape of heavy economic losses.
Availability: Items available for loan: UVAS Library [Call number: 0868,T] (1).
16.
Clinicotherapeutic And Haematological Studies Of Coccidiosis In Qualis
by Muhammad Zahir Iqbal | Prof. Dr. Khalid Pervez | Dr. Kamran | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2005Dissertation note: The study was designed to compare the efficacy of different anticoccidials i.e. Coxigon and Toltrazuril and their effect on blood values in quails. A total of 100 young healthy quails were purchased and raised for a week in good husbandry and hygienic conditions. The birds were randomly divided into four groups i.e. A, B, C and D, comprising of 25 birds each. Group A was treated with Toltrazuril, while group B was treated Coxigon. Group C was infected, non medicated and group D was uninfected control group. All the groups except D were given primary challenge doses of infection. The oocysts count was done on day zero, 3, 5 and 7. Record of mortality, morbidity was kept and postmortem of dead birds was also performed. The data collected was subjected to statistical analysis using one way analysis of variance and least significant difference (LSD) test, to detect the differences between the treatments and means. It is concluded that Toltrazuril as anti-coccidial revealed significant (P<0.05) difference among all the treatments in terms of weight gain, feed efficiency, oocyst count, reduction and decrease in mortality ratio and help a lot to normalize the blood values of quails. The results of other anti-coccidial i.e. Coxigon was not satisfactory, due to less decrease in mortality ratio, feed intake and weight gain and help little to normalize their blood values, and group C was infected non medicated showed great mortality and morbidity rate as compared to other groups. The results of this study will help to the Feed Farmers in choosing the best anti-coccidial drug, while the farmers will get choice amongst anti-coccidial drugs.
Availability: Items available for loan: UVAS Library [Call number: 0872,T] (1).
17.
Prevalence Of Ecto And Endo Parasites In Cross Bred Cattle At Lahore And Its Chemotherapy With Ivermectin
by Saleem Khan Niazi | Dr. Muhammad Sarwar Khan | Dr. Azhar | Prof. Dr. Khalid Pervez | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2003Dissertation note: The present project had been designed to study the prevalence of Ecto and Endo parasites in crossbred cattle of all age groups and to test the efficacy of ivermectin (Ivergen-Symans) at recommended
dose rate by the company against ecto and endo parasites in naturally infected cross bred cattle. For this project 400 crossbred
cattle were scanned to isolate 60 infected animals.
These 60 animals were divided in to 3 main groups i.e. A, B, and C, comprising 20 animals each. Each main group was subdivided into four sub groups, comprising 5 animals each and were marked as Al, A2, A3, & A4, Bi, B2, B3, B4 and Cl, C2, C3 & C4.
Out of total 400 animals, which were scanned 278 (69%) animals were found positive having ecto- endo- and mixed parasitic infection. Faecal samples of all 400 animals were tested for GIT nematodes, out of which 158 (40%) animals were found positive, skin scrappings of all 400 animals were tested for ecto-parasites, out of which 68 (17%) animals were found positive. 52 (13%) animals were found positive for mixed infection of both ecto- and endo-parasites.
The results of the present study revealed that Ivergen is highly effective at extremely low dosage against wide variety of nematodes and arthropods parasite, so it is recommended for field use.
Availability: Items available for loan: UVAS Library [Call number: 0873,T] (1).
18.
Comparative Efficacy Of Various Drugs Against Git Nematodes And Their Effect On Blood Parameters In Sheep And Goats
by Naseeb Ullah | Prof. Dr. Khalid Pervez | Dr. Kamran | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2004Dissertation note: The present project was designed to study the comparative efficacy of various drugs; 1) Albendazole (Farbenda), 2) Oxfendazole (Oxafax) and 3) Karanjwa (Caesalpenia crista) against naturally infected GIT nematodes in sheep and goats under field condition in and around district Kohlu, Balochistan and to find out their effect on some blood parameters; 1) Haemoglobin, 2) Total leukocyte count and 3) Differential leukocyte count and to detect the prevalence
For this purpose 180 sheep and goats naturally infected coprologically were examined. Out of 180 sheep and goats 106 were found positive showed 58% prevalence. For the treatment protocol, forty naturally infected and ten non-infected were selected and divided randomly into five groups having ten sheep and goats in each group viz A, B, C, E and D. Group A was treated with Albendazole 1ml/20mg body weight. Group B was treated with Oxfendazole 1ml/5kg body weight. Group C was treated with Karanjwa (Caesalpenia crista) @ 2mg/kg body weight. Group E was kept infected non-medicated control group. Group D was kept non-infected non-medicated control group.
In group A the eggs per gram of faeces were 22,700 on day zero and no eggs were found on day 7th which was treated with Albendazole. It has been observed from the result that Albendazole showed 100% efficacy on day 7th. In group B which was treated with Oxfendazole with egg per gram of faeces were 23,200 on day zero 22,800 on day 7th and no egg were found on day 14th. It has been observed from above results that the Oxfendazole shown 95% efficacy on day 7th and 100% efficacy on day 14th. In group C which was treated with Karanjwa, the eggs per gram faeces were 19,500 on day zero 22,100, on day 7th 31,800 on day 28th. Group E which was kept infected non-medicated control group, the egg per gram were found on day zero, 7th, 14th, 21st and 28th, 20000, 23700, 27500, 31200 and 35300.
On the haematological study the haemoglobin and lymphocyte level were decrease as compared to non-infected control group whereas the value of leukocyte, neutrophil, monocyte and eosinophil were increased as compared to normal group. In group A and B the haemoglobin and lymphocyte value slightly increase on day 7th, 14th, 21st and 28th post-medication. Moreover, the values of leukocyte, neutrophil, monocyte, eosinophil and basophil were slightly decrease on day 7th, 14th, 21st and 28th post-medication in group A and B. It has been observed from above study that Albendazole and Oxfendazole shown their effect on blood parameters, whereas group C which was treated with Karanjwa have shown no effect on faecal egg count and blood parameters.
Availability: Items available for loan: UVAS Library [Call number: 0902,T] (1).
19.
A Study Of Babesiosis In Calves At Livestock Experimental Station, Qadirabad And Adjacent Areas
by Nadeem Niazi | Prof. Dr. Khalid Pervez | Dr. Javed Iqbal | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2006Dissertation note: Bovine babesiosis (Piroplasmosis, Texas fever, redwater, tick fever) is a febrile, tick-borne disease of cattle, caused by one or more protozoan parasites of the genus Babesia and generally characterized by extensive erythrocytic lysis leading to anemia, icterus, hemoglobinuria, and death.
There are probably at least six Babesia species responsible for bovine babesiosis. Most can be categorized as being small or large Babesia. Morphological and serological differences are used to distinguish the different species. The two that are of most concern in our country are Babesia bigemina and Babesia bovis which are inflecting considerable losses to the livestock especially cattle.
The present study was conducted to find out the prevalence of babesiosis in cow calves at livestock experimental station Qadir Abad and adjacent areas of District Sahiwal and to find out the comparative efficacy of two babesicidal drugs i.e Fa-try-banil (diminazene aceturate) Prix Pharmaceutica. Lahore, Pakistan and Imizol (Tmidocarb dipropionate) ICI, Pakistan. In this study effect of babesiosis on different blood parameters i.e hemoglobin estimation and total ervthrocytic count was also studied.
For this purpose 415 calves were examined for the presence of babesiosis. Out of these 30 calves were found positive showing 7.2 percent prevalence. For treatment purpose 40 calves were selected randomly i.e. 30 infected and 10 healthy. i'hcse were divided into 4 groups A, B, C and D comprising 10 animals each. Diagnosis was confirmed on the basis of blood smear method. The animals of group A were treated with Fa-try-banil (dirninazene aceturate) @ 3.5 mg/kg body weight intramuscularly at day zero.
Four out of 10 calves recovered at 3" of injection, one calf recovered 7 day of 1S' injection, 4 calves recovered at 10th day of injection. This drug showed 90% efficacy while the calves of group B were treated with Imizol (Imidocarb dipropionate) lml/l00 kg body weight at day zero. Seven out of 10 calves recovered at 3rd day of injection, two recovered at 7 day of injection and remaining recovered at l0" day of 1S1 injection. This drug showed 100 percent efficacy at 10th day. Animals of group C served as infected untreated control and group D served as healthy non-infected control. Comparative efficacy of both the drugs was determined on the basis of disappearance of clinical signs and babesia from the blood. No side effects of the drugs were noted.
Haematological examination revealed a significant decrease in haemoglobin concentration and total erythrocytic count pre-medication. It has been observed from the present study that Imizol was the drug of choice for the treatment of babesjosis in calves.
Availability: Items available for loan: UVAS Library [Call number: 0908,T] (1).
20.
Incidence Of Ecto Parasites &Therapy Of Tick Infestation In Cattle Of District Dera Ghazikhan
by Muhammed Ramzan | Prof. Dr. Khalid Pervez | Dr. Allah Devyia Khan Khosa | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2006Dissertation note: The project was designed to find out the prevalence of ecto-parasites and to evaluate and compare the efficacy of Ivermectin, Doramectin and Azadirachta Indica (Neem) against tick infested cattle. These animal were randomly divided in groups i.e. A, B, C, D and E having ten animal in each group. Animal in group A, B, C were treated with Ivermectin, Doramectin and Azadirachta Indica (Neem). Animals in group D served as infected non-treated whereas animals in group E served as healthy and un-treated control. The efficacy of Ivermectin, Doramectin and Azadiracht Indica (Neem) on 14thi day post-treatment 100%, 60% and 0% respectively. Whereas animals in group D remained positive throughout the course of treatment whereas healthy animals in group E remained negative throughout the course of treatment from this result it was noted that Ivermectin is the drug of choice in the treatment of tick infestation. No side effect were observed with this drug.
Availability: Items available for loan: UVAS Library [Call number: 0914,T] (1).
21.
Sero-Epidemiological And Haematological Studies On Toxoplasmosis In Cats, Dogs And Their Owners in Lahore
by Azeem Shahzad | Dr. Muhammad Sarwar Khan | Mr. Kamran | Prof. Dr. Khalid Pervez | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2005Dissertation note: Toxoplasmosis is a parasitic zoonosis with worldwide distribution, caused by Toxop1asna gondii and is very common in cats, dogs and human. Keeping in view the zoonotic importance of the disease, the current study was conducted to find out the epidemiological status of toxoplasmosis in cat, dog and human population in Lahore city and to determine the possibility of transmission of toxoplasmosis from cats and dogs to their owners. For this purpose serum samples from cats (ii=25 domestic, n=25 stray) dogs (n=50 domestic, n=50 stray) and human (n=25 cat owners, n=50 dog owners, ii=50 people having no contact with cats and dogs, ii=25 UVAS, Employees) were collected and analyzed by using Latex Agglutination Test (LAT) to find out the prevalence of toxoplasmosis in cat, dog and human population.
Overall 56% cats were seropositive for anti-toxoplasma antibodies. Stray cats had the high prevalence (64%) followed by domestic cats (48%). Overall, 53%, 25%, 10.7%, 10.7% cats were seropositive at screening dilution of 1:16, 1:64, I : 128 and 1:256, respectively. The highest prevalence (71%) was detected in cat in the 7 year or above age group. Neither of the positive rates was found to be different between male (56.5%) and female (55.5%). The sero-positivity percentage of toxoplasmosis was highest in local breeds of the cats (64%) followed by Himalayan and Persian (50%) and Siamese breed of cat (46%). Furthermore the domestic cats, which had wandering habits, had higher seropositivity (62%) than the cats, which had not these habits (41%). The prevalence of toxoplasmosis was high in the cats receiving raw meat (66%) however the prevalence in the cats receiving commercial cat food and kitchen prepared/left over human food was 40% and 44.4%, respectively.
Overall 39% dogs were sero-positive for anti-toxoplasma antibodies. Stray dogs had the high prevalence (50%) than the domestic dogs (28%). Overall 46%, 28.2%, 15.3% and 10.2 % dogs were sero-positive at screening dilution of 1:16, 1:64, 1:128 and 1:256, respectively. The highest prevalence of toxoplasmosis (45.9%) was recorded in dogs of age group of >1-3 years. Neither of the positive rates was found to be different between male (35.4%) and female (35.4%). The sero-positivity percentage was highest in local breeds of dogs (50%) followed by German Shepherd (42%), Bulldog , Labrador Retriever and Russian (33%), English Pointer (30%), Alsatian, Bull Terrier and German Pointer (25%) and Greyhound (20%). Dogs having access to house as well as yard has the highest prevalence (40%) following the dogs having access only to yard (25%) and the dogs kept strictly at homes had the lowest prevalence (16%). Dogs fed raw meat had a relatively high prevalence of toxoplasmosis (40%) than the dogs fed commercial dog food and home cooked food had prevalence of 18.7% and 2 1.4%, respectively. Overall 22% human were sero-positive for anti-toxoplasma antibodies. The highest seropositivity was observed in cat owners (3 2%) followed by dog owners (26%), UVAS, employees (20%) and the lowest sero-positivity (14%) was observed in people having no contact with dogs and cats. Overall 63.6%, 27.2%, 3.0% and 6.0% human were seropositive at screening dilution of
1: 16, 1:64, 1: 128 and 1:256, respectively. The highest prevalence of toxoplasmosis (26%) was observed in people of 30-40 years or above age group. Neither of the positive rates was found to be different between male (21.9%) and female
(22.2%).
There was decrease in haemoglobin level of cats, dogs and human positive for anti-toxoplasma antibodies. There was significant decrease in total leukocytic count of cats, dogs and human positive for anti-toxoplasma antibodies. Nutroplielia, lymphocytopenia, cosinopenia and monocytopenia was observed in cats, dogs and human positive for anti-toxoplasma antibodies.
Availability: Items available for loan: UVAS Library [Call number: 0920,T] (1).
22.
Clinico-Therapeutical And Haematological Studies On Babesiosis In And Around The Livestock Experimental Station Qadirabad in Lohi Sheep
by Asif Rashid | Dr. Jawaria Ali Khan | Dr. Javaid Iqbal | Prof. Dr. Khalid Pervez | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2006Dissertation note: Ovine Babesiosis is a serious haemoparasitic disease of sheep. it is caused by two hemosporidian parasites i.e. Babesia motasi and Babesia ovis, transmitted by ticks. The disease results into death due to fever, excessive destruction of RBC's, anemia, haemoglobinuria and icterus. The present study was conducted to find out the prevalence of babesiosis in Lohi sheep in and around the Livestock Experimental Station, Qadirabad and to study the effect of 2 anti-protozoan (babesicidal) drugs i.e.Diminazene diaceturate (Diminazene; star lab.) and Imidocarb dipropionate (Imizol; ICI) on the recovery and health of animal. The effect of hernosporidian parasites on various blood parameters was also studied. The parameters included: Haemoglobin (Hb) estimation and Packed Cell Volume (PCV).
For this purpose 310 Lohi sheep were examined for the presence of babesiosis. Out of 310 Lohi sheep, 30 were found positive showed 9.67% prevalence. For treatment protocol, thirty naturally infected and ten noninfected sheep were selected and divided into four groups having ten sheep in each group i.e. A, B, C and D.
Diagnosis was confirmed on the basis of blood smear method, which revealed the presence of Babesia. The parasite appeared as piriform bodies within the light pink erythrocytes.
The animals of group A were treated with diminazene (Diminazene diaceturate) at a dose rate of 3.5mg/kg body weight at zero day. Three out of ten animals recovered at 3rd day of first injection, three animals recovered at 7th day of first injection, two recovered at 10th day of first injection, while two animals did not show any improvement and might be chronically infected. This drug showed 80% efficacy at 10th day while the animals of group B were treated with Imizol (Imidocarb dipropionate) at a dose rate of 2mg /kg body weight at zero day. Six out of ten animals recovered at 3rd day of first injection, three recovered at 7th day of first injection and remaining one recovered at 10th day of first injection. This drug showed 100% efficacy at 10th day. Animals of group C were served as infected untreated control while animals of group D were served as healthy control.
Efficacy of drugs was detected by negative blood smear. Imizol gave best results where as Diminazene was second in efficacy against babesiosis.
Haematological examination revealed a significant decrease in .Hb and PCV in group A and C on 3rd, 7th and 10th day post medication as compared to group B.
From the results of present study, it has been concluded that Imidocarb dipropionate (Imizol) was the drug of choice for the treatment of ovine babesiosis in Lohi sheep when given at the dose rate of 2mg/kg body weight by intramuscular route.
Availability: Items available for loan: UVAS Library [Call number: 0921,T] (1).
23.
Prevalence And Chemotherapy Of Balantidium Coli In Cattle Around River Ravi Bank Lahore
by Ch. Qasim Bilal | Prof. Dr. Khalid Pervez | Dr. Muhammad Sarwar Khan | Prof. Dr. Haji | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2006Dissertation note: The present project was designed to find out the prevalence of Balantidium coli and to evaluate the efficacy of Terramycin, Dysen forte, Flagyl against naturally occurring balantidosis in cattle under field conditions around the river Ravi bank Lahore. The faecal samples from animals were collected directly from rectum of animals and brought to the laboratory of Department of Clinical Medicine and Surgery, University of Veterinary and Animal Sciences, Lahore for coprological examination.
For this purpose two hundred cattle were examined coprologicaly around the bank of river Ravi in Lahore. Out of 200 cattle, 50 were positive, so the prevalence of Balantidium coli in cattle was 25%. Out of 50 positive animals thirty two cattle having balantidiosis were selected for chemotherapeutic trials and eight non effected cattle were selected and divided into five groups viz. A, B, C, D and E comprising eight animals each. The animals of Group-A were treated with oxytetracycline capsules (Terramycin) @ 8mg/kg orally, Group-B with secnidazole tablets (Dysen forte) @ 10mg/kg orally, Group-C with metronidazole tablets (flagyl) @ 25mg/kg orally. The animals in Group-D were serving as infected untreated control group and Group- E were serving as untreated healthy control.
The efficacy of drugs was evaluated on the basis of disappearance of clinical signs and by reduction in number of cysts/trophozoites on zero, 3, 7 and 1 0 day post medication. Efficacy of oxytetracycline (terramycin) was 25%, 50% and 62.5% on 3, 7 and 10 day, respectively. Efficacy of secnidazolc (dysen forte) was 37.5%, 75% and 87.5% on 3, 7 and 10 day, respectively. Efficacy of metronidazole (flagy) was 12.5%, 25% and 37.5% on 3, 7 and 10 day, respectively.
It was concluded from the above results that Dysen Forte was more effective than Terrarnycin or Flagyl. However, Terramycin showed better efficacy than that of Flagyl.
Availability: Items available for loan: UVAS Library [Call number: 0927,T] (1).
24.
Clinico-biochemical Studies on Detomidine Analgesia and Effects of its Combinatios on Animals
by Muhammad Arif Khan | Prof. Dr. Muhammad Ashraf | Dr. Khalid Pervez | Dr. Haji Ahmad Hashmi.
Material type: ; Literary form:
not fiction
Publisher: 2003Dissertation note: The overall objective of this study was to evaluate the newly introduced imidazole derivative, drug "detomidine" with alpha-2 adr2noceptor binding properties, and its various combinations in animals. A clinico-hiochemical study was carried out to explore the various aspects of a novel sedative and analgesic drug. Analgesia was evaluated by performing castration in small ruminants, rumenal fistulization in large ruminants, skin prick test, electric stimulation, and developing an experimental colic model in donkeys. The parameters used to evaluate analgesia revealed that detomidine has greater potential to lessen the pain during minor and major surgical interventions in different animals. However, its local usage to achieve paravertebral and epidural analgesia proved that detomidine produces general effect after getting into the circulation and very poor local effect. It has been concluded that the drug can be used as preanaesthetic with chloral hydrate and pentothal sodium anaesthesia to perform major surgical exercises in equine and canine respectively. In addition it has an edge over other sedative drugs on account of its undetrimental effect on various physiological parameters of the animals. Clinical trials have proved that detomidine "a novel sedative and analgesic" is a drug of choice for restraining, examination, and minor and major surgical manipulations on equine, bovine, caprine, ovine and canine species without any untoward effects. Availability: No items available Checked out (1).
