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1. Comparative Efficacy Of The Transverse Pylorpplasty And Y-U Advancement Pyloroplasty As A Relief To Pyloric Stenosis in Dogs

by Ayesha Safdar Ch | Dr.Muhammad Arif Khan | Dr.Asim Khalid Mehmood | Prof.Dr..Zafar | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2007Dissertation note: Stomach is important and biggest dilatation of alimentary canal which mainly serves the purpose of digestion of food. The stomach has two extremities cardia and pylorus, it also has fundus and body. The pyloric extremity is connected with the duodenum by pyloric canal. The gastric emptying of food is controlled by pyloric sphincter. Many problem have been diagnosed in the pylorus such as gastric and duodenal ulcers, neoplaisa, chronic gastritis, drugs and chemicals resulting in pyloric stenosis. Various surgical attempts were made in the past to treat such problems, these includes pyloromyotomy, pyloroplasty, transverse and YU advancement pyloroplasty and partial or complete pylorectomy. Keeping in view the importance of this part of stomach two surgical procedures were tried Transverse pyloroplasty and YU advancement pyloroplasty as a solution to the obstructive problems of the pylorus. Although these techniques are well established methods and have been used by the various surgeons in the past as a remedy to the stenotic problems of the pylorus but no work has been done on comparative efficacy of these two procedures concerned. The present project was designed to study the comparative efficacy of these two techniques. Twelve healthy mongrel dogs were selected and were divided into three groups comprising four animals each.ln group A Transverse Pyloroplasty , in group B YU Advancement Pyloroplasty was performed and dogs of C group were kept as control. The efficacy of the procedures was evaluated on basis of physical examination, radiographic evaluation, and postmortem examination. Laparotomy was performed in aseptic condition and pylorus was exteriorized in both the groups. In dogs of group A, longitudinal incision was given over the pylorus which was closed in transversed fashion. After checking any leakage at the operated site the abdomen was closed in routine manner. In group B, Y shaped incision was given at the pylorus which was converted into U. Dogs of group C were kept as control and they were not subjected to any surgical procedure. Barium study procedure was performed in the dogs of all groups to estimate the rate of gastric emptying and post mortem was preformed to evaluate the change in diameter of the pylorus. The results of this study clearly indicated that although both the techniques are effective in increasing the diameter and improving the gastric emptying but Y U Advancement Pyloroplasty was more useful and effective procedure. Availability: Items available for loan: UVAS Library [Call number: 0988,T] (1).

2. Repair Right Sided Diaphragmatic Hernia Using Autogenous Jejunal Graft In Dogs

by Miss Rasha | Prof.Dr.Muhammad Arif Khan | Dr.Asim Aslam | Dr.Asim Khalid Mehmood | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2008Dissertation note: The present study was conducted to evaluate the viability and healing process of the perfused jejunal graft as an implant for the repair of canine diaphragmatic hernia. Diaphragmatic defect was created in 12 healthy mongral dogs irrespective of age and sex. A window was established through obliqus externus and obliqus internus muscles to have an access to the diaphragmatic crus. The jejunum was identified through the same window and a part of required dimension was ressected with intact blood supply. After resection the integrity of jejunum was restored by end to end anastamosis. After making the window identifies the jejunum. And ressect the selected part according to the diaphragmatic defect along with its blood supply. Then the jejunal graft was sutured on the diaphragmatic defect. A diaphragmatic defect of 4X4cm in size was created experimentally on right muscular portion of diaphragm through subcostal/paracostal approach. Experimental dogs were evaluated individually at 20th, 40th and 90th day post operatively .The defect was later on grafted using autogenous perfused jejunum. The size of jejunal graft was sufficient enough to cover the defect 4X4cm created in diaphragm. Clinical examination of the experimental animals was conducted in respect of dyspnea, signs of shock, cynosis and pain. The observations, with respect to the given parameter varied significantly. Physical examination of experimental animals was undertaken with respect to body temperature, pulse rate, respiration rate during post-surgical period. All the dogs showed good post-surgical recovery with minor complication only in the first week after surgery. Diaphragmatic outline was found intact when examined through plain chest radiography. Post-mortem examination revealed no evidence of discoloration, necrosis, injuries and bleeding but the adipose tissue deposit were found at the site of diaphragmatic repair. Histopathological examination of repaired site of diaphragmatic defect revealed fibrous tissue deposits. CONCLUSION The results of present study clearly indicated that the use of perfused jejunal graft with intact blood supply was a viable option and a better choice for the repair of diaphragmatic defect through right paracostal/ subcostal approach in dogs. The use of perfused jejunal graft resulted in lower chances of infection in comparison with synthetic! mesh material reported in literature and was also an economical procedure for the repair of diaphragmatic hernia. RECOMMENDATION Based on the findings of the present study use of autogenous perfused jejunal graft with intact blood supply is recommended as first choice of surgical treatment for the repair of diaphragmatic hernia. Availability: Items available for loan: UVAS Library [Call number: 1006,T] (1).



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