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Effect On Lipid Profile Parameters By The Addition Of Orange Juice In Diet Of Hypercholesterolemic Patients

by Zeshan Ali (2012-VA-616) | Dr. Naureen Naeem | Dr. Sanaullah Iqbal | Mrs. Rahat Naseer.

Material type: book Book; Literary form: not fiction Publisher: 2015Dissertation note: Orange juice;arich source ofvitamin C,folate,andflavonoidssuchashesperidine, induceshypocholestremicresponsesinanimals.Previousepidemiologicstudiessuggestedthat ahighintakeoffruitandvegetablesisassociatedwithareducedriskofcoronary heartdisease(Borsetal.1990).Thebeneficialeffectcould berelatedtominorcomponents,especially flavonoids,whichare proposedtoexerttheiractionby inhibitingLDLoxidation (CooksandSamman1996).Orange juice might beneficially decrease blood lipid profile in subjects with hypercholesterolemia(Charleux1996). Fiftysubjectshavingelevated totalcholesterol andLDLcholesterolincludedin thestudy.Participantswas incorporate2cups(5000mL)oforange juicedailyintotheirdiets,eachdoseoveraperiodof3 weekfollowed by a 5-weekwashoutperiod.Plasma lipid,folateandvitaminC(acompliance marker) concentrationsmeasuredat baseline,aftereach treatment, and afterthewashout period.Obtained resultswereanalyzedbyusingstatisticaltoolANOVA (two-way)onStatistical PackagefortheSocialSciences (SPSS) softwareversion 21.0.0.Attheendofthis studywewereabletoconcludethe variationin lipidprofile parametersbyorangejuiceconsumption.EitherOrangejuicecanbeusedtoimproveblood lipidprofilein hypercholesterolemicsubjects. At the end of the study period the significantly increased HDL- cholesterol and decreased LDL-HDL cholesterol ratio had not reverted to initial values. In fact, the decrease in the LD-HDL cholesterol ratio and increased HDL- cholesterol at the time of washout tend to be higher as compared to the detected in 3rd period. Moreover it was also observed that subjects consuming processed orange juice showed different results of HDL and LDL-HDL cholesterol concentration, subjects consuming fresh orange juice had elevated level of HDL and decreased ratio of LDL-HDL ratio as compared to those who intake commercially available processed orange juice. Availability: Items available for loan: UVAS Library [Call number: 2309-T] (1).

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Association Of Skipping Breakfast With BMI, Metabolic Syndrome And Cardiovascular Risk Factors In University Going Students

by Shakeel Ashraf (2012-VA-627) | Dr. Naureen Naeem | Dr. Sanaullah Iqbal | Mrs. Rahat Naseer.

Material type: book Book; Literary form: not fiction Publisher: 2015Dissertation note: Metabolic syndrome can be defined as disorder of energy utilization and storage, its diagnosis can be done if three out of five medical conditions occurs at the same time that are abdominal obesity, increased blood sugar level, elevated blood pressure, high serum triglyceride and low HDL levels in serum Previous studies have shown that there is strong association between skipping breakfast and metabolic syndrome. Skipping breakfast results in metabolic diseases like obesity, cardiovascular disease, high blood pressure, diabetes, increased lipid profile. Two hundred students of university of veterinary and animal sciences and their acquaintances were selected with age ranging from 20-25 years. Fasting blood samples were collected from university students for biochemical analysis of lipid profile that included cholesterol, triglyceride, HDL and LDL and Glucose levels were determined using biochemical analyzer (Micro lab 300, Merk). Anthropometric measurements were done using their respective tools. The distribution of subjects in breakfast consumption groups was evaluated using the χ2 test. The mean and standard differences deviation were calculated for each breakfast consumption group. At the end it is concluded that skipping of breakfast might have hazardous effect on diet quality and metabolic disease risks. This can lead to development of potential hazardous risk factors like central abdominal obesity, elevated cholesterol, triglycerides and LDL levels and decreased HDL levels. These risk factors if uncontrolled can lead to disease like diabetes, hypertension and heart attack in old life. Availability: Items available for loan: UVAS Library [Call number: 2391-T] (1).

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