1.
Prevalence And Chemotherapy Of Strongylosis And Its Effect On Various Blood Parameters In Horses
by Abid Saleem | Dr.Khalid Pervez | Dr.Haji Ahmad | Dr.Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1998Dissertation note: The present project was designed to find out the prevalence of strongylosis, to test the anthelmintic efficacy of Albendazole, Oxfendazole and Piperazine and to study the effect of strongyloids on blood parameters.
For this purpose the faecal samples of one hundred and twenty horses were processed through coprological examination. Out of 120 horses 68 were found positive, so the prevalence of strongylosis was recorded as 56.66%. Out of the positive animals, 60 were randomly divided into four groups A, B, C and D comprising of 15 animals in each group. Each animal of group A was given Farbenda (7.5 mg/kg body weight), group B was given Oxafax (10 mg/kg body weight), group C was given Coopane (0.2 g/kg body weight) while group D was kept as control (untreated). The efficacy of anthelmintics was evaluated on the reduction of eggs per gram (EPG) of faeces on 7th, 14th and 21st day post-medication. Efficacy of Farbenda (Albendazole) was 64.2%, 53.1% and 42.1% on 7th, 14th and 21st day, respectively. Efficacy of Oxafax (Oxfendazole) was 100%, 98.7% and 98.1% on 7th, 14th and 21st day, respectively. Efficacy of Coopane (Piperazine) was 52.3%, 38.8% and 28% on 7th, 14th and 21st day, respectively. It was concluded from above results that Oxfendazole was found the most effective than Albendazole and Piperazine, while Albendazole showed better efficacy than Piperazine.
Haematological parameters showed significant reduction in total erythrocyte count (TEC), haemoglobin (Hb) level and packed cell volume (PCV) while total leukocyte count (TLC) remained within normal limits.
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2.
Prevalence Of Trichomoniasis In Domestic And Wild Pigeons And Its Effect On Some Blood Parameters Nd Weight Gain
by Hassan Saleem, M | Dr.Khalid Pervez | Dr.Kamran | Dr.Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1999Dissertation note: The present project was designed to study the prevalence of Trichomonas gallinae (Trichomoniasis) in domestic and wild pigeons and its effect on some blood parameters and also on weight gain.
To find out the prevalence of T. gallinae in domestic and wild pigeons 100 pigeons were examined between March and Apr11, 1998 from different shops of New Tollinton Market and Lahore Zoo, Lahore. The overall prevalence in domestic and wild pigeons was 41%, which was 30% in March and 52% in April. The birds which were kept in unhygienic conditions and ill fed had more chance of having T. galllnae and have higher prevalence.
For the haematological study 10 healthy and 10 infected pigeons were randomly selected (from the already tested -ye and +ve of the infection) and their blood was examined for ITh, Tl.C, DLC and
PCV. The values of Hh, PCV and Monocytes of unhealthy pigeons are lesser than the healthy pigeons, while values of TLC, hetorophils, lymphocytes and Eosinophils are higher in diseased pigeons than the healthy pigeons. There is a significant difference between the means of Hb, PCV, TLC, Monocytes, Lymphocytes, Eosinophils, while there is no significant difference between the means of Ileterophils.
Finally for weight gain 10 healthy and 10 infected pigeons were randomly selected from already tested and confirmed -ye and +ve pigeons and weight them very carefully and recorded. Both types of birds were kept under observation and after 4 days again weighed them. Which showed that apparently the infected pigeons had lesser weight than healthy ones. There is also a significant difference between their means.
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3.
Comparative Efficacy Of Various Drugs Used Against Equine Colic
by Hamad Bin Rashid | Dr.Khalid Pervez | Dr.Asim Aslam | Dr.Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1999Dissertation note: Horse is a delicate animal and has a marked tendency towards gastro-intestinal disorders. Unlike other diseases of equines, colic provides the horse a lot pain, the veterinarian and the horse owner much anguish and loss. This study was designed to evaluate the efficacy of hyoscine-n-butylbromide, pentazocine lactate and detomidine hydrochloride. Eighteen horses suffering from colic brought to the Veterinary Hospital, Lahore Race Club, Lahore and the Outdoor Hospital, College of Veterinary Sciences, Lahore were used in this study, while 6 normal horses were kept as control. rI1i diseased horses were randomly divided into A, B and C groups. The physical examination of the affected animals was performed to determine the degree of dehydration, PCV and concentration of serum electrolytes i.e. Sodium, Potassium, Chloride and Bicarbonate were measured before treatment, 1 hour and 2 hour post treatment by flame photometry.
In healthy animals PCV and serum electrolytes were in normal range. Increased PCV was observed in most of the affected horses (range 27-64% Mean 43.22%). One hour after the treatment the PCV ranged from 29.1-62.8% (Mean 43.82) while after 2 hours, It was 30.82-60.1% (Mean 43.77%). The lower values of PCV could be attributed to parasitic anaemia. Serum Sodium, Chloride and Bicarbonate concentrations were decreased i.e. 108-13 1 mEq/L (Mean 118.88), 70-91 mEq/L (Mean 79.26) and 23.3-31.1 mEq/L (Mean 26.67) respectively. While serum Potassium concentration was increased i.e. 3.0-5.4 mEq/L (Mean 4.25). One hour after the treatment the values of Nat, OF, HC03 and K were 108.8-132.4 (Mean 121.1), 74.1-94 (Mean 81.6), 24-31.4 (Mean 27.24), 3.3-5.2 mEq/L (Mean 4.39), respectively, while 2 hours after the treatment the values of Na, CF, HC03 and K were 109-133.1 (Mean 122.97), 74.5-99 (Mean 83.55), 24.5-31.9 (Mean 27.83) and 3.7-5.1 mEq/L (Mean 4.53) respectively. The efficacy of hyoscine-n-butylbromide was 100% within 5 hours post treatment. The efficacy of pentazocine lactate was 100% within 4 hours post treatment, while the efficacy of detomidine hydrochloride was 100% 4 hours post treatment. Among pentazocine and detomidine, the efficacy of detomidine was better as more horses recovered in the same time period as compared to pentazocine.
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4.
Prevalence & Chemotherapy Of Ascariasis & Its Effect On Various Blood Parameters In Horses
by Saqlain Shah Bukhari | Dr.Khalid Pervez | Dr.Muhammad Sarwar Khan | Prof.Dr.Muham | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1999Dissertation note: (Albendazole) was 64.95%, 52.26% and 44.02% on 7th, 14th and 21st day, respectively. Efficacy of Oxafax (Oxfendazole) was 99.18%, 98.36% and 97.95% on 7th, 14th and 21st day, respectively. Efficacy of Ivomec (Ivermectin) was 100%, 10O% and 100% on 7th, 14th and 21st day, respectively. It was concluded from above results that Ivermectin was found the most effective than Albendazole and Oxfendazole, while Oxfendazole showed better efficacy than Albendazole.
Haematological parameters showed reduction in total erythrocyte count (TEC), haemoglobin (Hb) level and packed cell volume (PCV).
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5.
Prevalence Of Nematodes & Comparative Efficacy Of Albendazole, Mebendazole & Niclosamide Against Nematodes, In Wild Felidae
by Waqar Ali Khan | Dr.Khalid Pervez | Dr.Haji Ahmad | Dr.Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1996Dissertation note: The present study was conducted to estimate the efficacy of Bovisol (Albendazole), Vermox (Mebendazole) and Yomesan (Niclosamide) against nematodes i.e. Toxocara canis, Toxocara mystax and Ancylosloma braziliense in wild felidae, kept in captivity in Lahore Zoo and Lucky Irani Circus, because wild felidae are prone to a number of parasitic infection and zoological gardens served as permanent source of parasitic infestation.
A survey was carried out to estimate the prevalence of Toxocara canis, Toxocara mystax and Ancvlostoma braziliense in wild felidae kept in Lahore Zoo and Lucky Irani Circus. The incidence rate of these parasites was 84.62%, 84.62% and 69.23%, respectively in the Lucky Irani Circus; and 62.07%, 48.28% and 20.69%, respectively in the Lahore Zoo. All the animals showing infection were selected for therapeutic trials.
The anthelmintic trials were conducted on 19 and 13 wild felidae kept in the Lahore Zoo and Lucky Irani Circus, respectively. In each experimental Station, i.e. the Lahore Zoo and Lucky Irani Circus, four groups designated A, B, C and D were made. Groups A, B and C were treated with Bovisol (Albendazole), Vermox (Mebendazole) and Yomesan (Niclosamide), respectively. While one group i.e. D, was kept as control (untreated). The percent efficacy of each drug was determined on the basis of reduction in the number of ova discharged in the faeces of experimental animals on 7th, 14th, 21st and 28th day after medication.
Results showed that Vermox (Mebendazole) and Bovisol (Albendazole) are approximately equally effective against roundworms and hookworms. Efficacy of Yomesan (Niclosamide) did not show good results throughout the experiment. The efficacy of all the three anthelmintics lowered down with the passage of time.
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6.
A Clinico Coprological Study & Comparative Efficacy Of Systamex, Albendazole, Ivomec Against Nematodes
by Ghulam Hassan | Dr.Khalid Pervez | Dr.Baig | Dr.Kamran Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2000Dissertation note: The present project was designed to find out the incidence of nematodes and to chalk out the comparative efficacy of Systamex, Albendazole, Ivomec against naturally occurring gastrointestinal nematodes in camel under field conditions in and around Lesbela District, Balochistan. For this purpose, 60 naturally infected camels were divided into 4 groups (15 camples in each group).
Group-A Systamex (Oxafendazole; ICI-Pakistan) was given at dose rate 1 ml/8 kg body weight.
Group -B Albendazole (Star Labs.) was given at dose rate of 5mg/kg body weight.
Group - C Ivomec (Rhone-Poulenc) injection was given at dose rate 0.2 mg/kg body weight subcutaneously.
EPG in four groups of animals a day before treatment was as under:
Camels in group-A received oxfendazole treatment, mean EPG was 1760. Mean EPG values calculated on days 7, 14, 21 and 28 were 400, 280, 120 and 55, respectively. The percentage efficacy on days 7, 14, 21 and 28 was 77.27%, 84.09%, 93.18% and 98.87% respectively.
Group B was treated with Albendazole, EPG values day 0, 7, 14, 21 and 28 were 2130, 630, 317, 190 and 95, respectively. The percent efficacy was 70.42%, 85.11%, 91.08% and 95.54% on day 7, 14, 21 and 28 respectively.
Animals in group C were treated with Ivermectin, mean EPG value on days, 0, 7, 14, 21 and 28 were 1950, 432, 285, 120 and 30, respectively. The percent efficacy was 77.85%, 85.38%, 93.85% and 98.46, respectively.
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7.
Studies On The Babesia Canis And Ticks Of Dogs
by Abdul Haseeb Khan | Haji Ahmad Hashmi | Dr.Khalid Pervez | Dr.Khalid Saeed | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2001Dissertation note: The present study was conducted from September to November, 2000 to find out the prevalence and taxonomy of ticks and Babesia canis of dogs. In addition, their effect on haematological parameters was also studied. To find out the prevalence, 759 dogs were included in the study. The samples were collected from the dogs brought to Dog Hospital, College of Veterinary Sciences, Lahore, Private Veterinary clinics and from different Private Kennels present in and around Lahore.
Out of the total 759 dogs, 205 (27 %) dogs were found positive for single species of ticks i.e. Rhipicephalus sanguineous and 179 (23.5%) dogs were found positive for Babesia canis. Seventy four (9.7%) dogs were infested with only ticks and 48 (6.3%) dogs were found positive for only Babesia canis. Out of total 205 ticks infested dogs, 131 (63.3%) were found positive for Babesia canis.
For haematological study from the total examined dogs 80 (60 infected, 20 healthy) were selected and divided in to four groups A (mixed infection of ticks and Babesia), B (ticks only), C (Babesia only) and D (non-infected). Each group comprising of 20 animals.
The total erythrocytic count were 2.5x106±0.28/,il, 3.2x106±0.21/iil, 3.6x106±0.13/id and 4.9x106±0.18/j.d of group A, B, C and ID respectively. There was significant difference amongst group A, B, and C as compared to the control group-D. A significant difference amongst A-B, A-C was also noted. But no significant difference between group B and C could be recorded.
Hemoglobin estimation in group A was 7.1±0.33 g %, in B was 9.2±0.30 g % and in group C was 9.8±0.30 g %. It was revealed that there was significant decrease in hemoglobin contents as compared to group 'D' which showed 12.01±0.6 g %. There was significant difference between group A-B and A-C, but no significant difference between group B-C (P<0.05) was noted.
The animals belonging to group A, B, C and D had ESR as 40.15±3 mm/hour, 32.25±0.17 mm/hour, 25.2±1.1 mm/hour, and 16.3±1.3 mm/hour respectively. There was significant difference amongst the groups A, B, C as compared to group D. There were also significant difference amongst groups A-B, A-C and B-C (P<0.05). The RBC of the groups A, B, and C were found crenated and macrocytic hypochromic.
The overall results showed that effects of mixed infection of ticks and Babesia on haematology were more adverse as compared to the single infections of ticks or Babesia.
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8.
Prevalence Of Tuberculosis In Cattle Around Lahore Using Intradermal Test
by Maqsood ur Rehman, Lt.Col | Dr.Khalid Pervez | Dr.Masood | Dr.Mohammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2001Dissertation note: The present study was designed to study the prevalence of tuberculosis in cattle in cattle-colony Rakh Chandrai-near Lahore using double intradermal tuberculin test using tuberculin prepared at Veterinary Research Institute, Ghazi Road, Lahore.
A total of 300 cattle of either sexes and having age groups in between 3-6 years, 6-10 years, 10 years and above were subjected to interdermal tuberculin. Veriner caliper was used for the exact measurement of the skin before injection tuberculin and 72 hours later. Their results were interpreted according to the standard procedure. No bull was found suffering from tuberculosis, similarly in the age group of 3-6 years no positive case was found. However, in the age group of 6-10 years, 4 cases were found positive and in age group 10 years and above, 6 cases were positive. Generally tuberculosis was positive in emaciated and debilitated animals and less common in fair animals.
The study has generally a help in diagnosing the prevalence of tuberculosis in cattle, particularly in the cattle colonies in the vicinity of Lahore. More studies are recommended in the area to estimate the prevalence of bovine tuberculosis on profound basis.
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9.
A Study On The Effects Of Chemotherapy On Experimentally Induced Heterakis Gallinarum Infestation Of Layer Chicks
by Aatif Haseeb Ahmad | Dr.Muhammad Sarwar Khan | Dr.Khalid Pervez | Dr.Muhammad | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Nature of contents: ; Literary form: Publisher: 2001Dissertation note: Heterakis gallinarum is the commonest nematode inhibiting the digestive tract of poultry that inflects heavy economic losses in poultry industry through causing anaemia, reduced production and loss of weight. These symptoms show that parasitic diseases are the constraints in the development of profitable poultry industry. The present study was conducted to access the effectiveness of Albendazole (Farbenda 10%, Farvet) and Fenbendazole (Hunter 10, Frontline) against j gallinarum and effects of parasitism on blood parameters such as haemoglobin, TLC, DLC and weight gain in layer chicks.
For this purpose, 80, 6-week old layer (Fayoumi) were purchased from the local market and 60 birds were infected with . gallinarum ova (100 ova/bird) through oral route while 20 bird were kept as non-infected (control). Five randomly selected birds were slaughtered post infection period at 15th day to confirm the maturity of worms. On 28th day post infection, birds were divided into 3 groups A, B and C (15 bird/group), 15 birds remained as control group D. Five randomly selected birds from each group were slaughtered and worm count was done. On the same day treatment trial were started. On 33rd day post-infection (5th day post-medication), all birds were slaughtered and effect of Albendazole and Fenbendazole was ascertained on the parasite by counting them. According to results obtained, Albendazole which was given to group A, was 78.88% effective while Fenbendazole which was given to group B was 72.22% effective against H. gallinarum.
Blood samples were taken on 28th day and 33rd day post infection (5th day post-medication) for haematological studies. Significantly lower values of haemoglobin were estimated in infected groups A, B and C as compared to control group D, while higher values were obtained for heterophil, monocyte, eosinophil and basophil resulting in overall increase in total leukocyte count (TLC).
Chicks of group A, B, C and D were weighed on weekly basis starting from 12th day post infection to see the effect of II. gallinarum on body weight. There was a significant decrease in weight in group A, B and C as compare to control group D. Clinical signs of the diseased birds were noted and at the end of experiment, post-mortem examination was done to examine the intestinal lesions.
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