UVAS Library

Your cart is empty.

Your search returned 2 results. Subscribe to this search

Not what you expected? Check for suggestions
Unhighlight Highlight
|
1.
No cover image available
Effects Of Infectious Bursal Desease Vaccine And Vaccination Schedule In Imunity Induceds By Newcastle Disease

by Kashif-ur-Rehman | Prof.Dr.Mansur-ud-Din Ahmad | Dr.Imran Najeeb | Prof.Dr.Azhar Maqbool | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2008Dissertation note: The study was carried out for verifying the interference of infectious bursal disease vaccines conmonly used in Pakistan on the immunity to Newcastle disease vaccines. Infectious bursal disease (IBD) is a viral disease producing suppression in humoral immune response causing degeneration of bursa of Fabricius. Different vaccines are available in the market for mass scale immunization of chickens. The study was carried out to compare the immunosuppressive effects of intermediate strain, hot strain and complex IBDV vaccines on immunity induced by NDV vaccine. Vaccine efficacy was studied by measuring the induced humoral antibody level using HI (Haemagglutination inhibition) test for NDV and indirect ELISA (enzyme-linked immunosorbent assay) (Kirkegaard' & Perry Laboratories - KPL) to detect antibodies against IBDV. The parameters used to evaluate the effects of IBDV vaccine on broiler chicks were immune response to NDV vaccination, weight of lymphoid organs such as bursa of Fabricius, thymus and spleen, post virulent NDV challenge and FCR. The results showed that IBDV vaccinated groups A, B, C, D and E had lower HI antibody profile, higher bursa, spleen and thymus body weight ratio, poor FCR and higher post challenge mortality than NDV vaccinated group F. The HI serum antibody profile revealed that the groups vaccinated with IBDV hot strain had significantly lower antibody titer as compared to the intermediate strain of IBDV vaccinated birds. In addition to that hot strain vaccine found to be more damaging to the bursa, spleen and thymus than the intermediate strain vaccine. The hot strain had adverse effects on the feed conversion ratio of birds as well. The challenge with virulent NDV revealed that IBDV vaccine treated groups were overall higher mortality than the only NDV vaccinated chickens. The study suggested the use of intermediate strain as vaccine since it had least interference with the antibody production against ND. However, hot strain used in this study had adversely affected the NDV HI. titer and caused more damage to the lymphoid organs and reduced feed conversion ratio (FCR). Availability: Items available for loan: UVAS Library [Call number: 1017,T] (1).

Place hold Add to cart
2.
No cover image available
Comparative Efficicy Of Peste Des Petits Ruminant (Ppr) Vaccine S Available In Pakistan In Sheep And Goats

by Muhammad Intizar | Prof.Dr.Manur-Din-Ahmad | Dr.Aftab Ahmad Anjum | Prof.Dr.Azhar | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Nature of contents: biography; Literary form: Publisher: 2008Dissertation note: The present study was designed to evaluate the physical factors affecting the PPR 'vaccine and also to compare the efficacy of the locally available PPR vaccines in Pakistan in sheep and goats. The current study was conducted on 120 different small ruminants ((60 sheep and goats). The humoral immune response was monitored by measuring the antibodies titre through Hl and AGID test. HI and AGID test are reliable and effective methods of diagnosing viral diseases and to evaluate the humoral immune response. It was concluded that the vaccine should he stored either at -20°C or at 4 C.The vaccine stored at 27 C had a drop in HA titre and no HA activity was found at 40 C To evaluate the HA activity of PPR virus it is better to use chicken or human group'O' R.B.Cs in a concentration of 1%. The diluent should have the pH 6.8- 7.0. By evaluating the vaccine efficacy in sheep it was found that after 14th day of vaccination there was a gradual increase in the antibodies titer till the 56th day of vaccination. The locally manufactured vaccine was having a geometric mean titre (GMT)207.9 while the (GMT) of Pestivec was 73.3. 63d day post vaccination. In goats the locally manufactured vaccine was having a geometric mean titer (GMT) 147. while the (GMT) of Pestivec was 48.5.63rd day post vaccination. No antibodies production was there in any control group. It was concluded form the study that locally produced vaccine is equally good and could be used confidently. It will save also helpful in saving the foreign reserves oh the country. Availability: Items available for loan: UVAS Library [Call number: 1051,T] (1).

Place hold Add to cart

Implemented and Maintained by UVAS Library.
For any Suggestions/Query Contact to library or Email:rehana.kousar@uvas.edu.pk Phone:+91 99239068
Website/OPAC best viewed in Mozilla Browser in 1366X768 Resolution.