1.
Prevalence Of G.Ilt. Namatodes In P:Heasants At Lahore Zoo/Jallo Wildlife Park & Its Chemotherapy With Oxfendazole (Oxafax) & Febental [Rintal]
by Makhdoom Najaf, Muftee | Muhammed Sarwer Khan | Dr. Muhammad Ashraf | Muhammed | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1993Dissertation note: This experiment was conducted to find out that efficacy of various anthelmintics in birds (Pheasants) for the treatment of Ascaridia, Heteraki and Trichostrungylus.
Thirty six pheasants naturally infected were selected for study. They were divided into 3 groups that in A, B & C. The anthelmintics used were Rintal and Oxafax. They were given to Group A, B respectively. Group C was considered as control to know the increase in the number of eggs per gm. of feces during the experimental period, showing the increase as 2375 and 2908 and 8.34% and 32.66% on third and seventh day of experiment.
Fecal samples were obtained from pheasants owing to Punjab Wildlife Department, i.e. Lahore Zoo and Jallo Wildlife Park, Lahore brought to Medicine Lab., College of Veterinary Sciences Lahore of -rye samples were done:
a. Before the administration of drugs.
b. After 3rd day of treatment.
c. After 7th day of treatment by using MC. Master technique.
As regards the efficacy of the drugs, the Rintal was found highly effective and reduced 90.58 eggs per grams of feces, Oxafax reduced 82.42%.
In addition to effectiveness, Rintal was also the cheapest, anthelinintic out of two. So Rintal was recommended for field use. It was observed thak incidence of infection (Ascaridia, Heterakis) in Lahore Zoo was 25% and incidence of infection in Jallo Wildlife Park was 23% overall incidence was 24%. In Lahore Zoo the prevalence was 60.11% for Ascaridia and for 1-leterakis 38.88% whereas in Jallo Wildlife Park, Lahore it was 65.21% for Ascaridia and for Heterakis 34.78% respectively.
Availability: Items available for loan: UVAS Library [Call number: 0172,T] (1).
2.
Study & Comparative Efficacy Of Oral & Injectable Levamisole Against G.I.T. Nematodes In Cattle And Buffaloes
by Anwar Hayat Hanjra | Muhammed Sarwer Khan | Dr. Muhammad Ashraf | Muhammed | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1991Dissertation note: This project was designed to find out the incidence of gastrointestinal nematodes and to chalk out the comparative efficacy of Levamisole Hcl oral and Levamisole Hcl injectable (Anthelmin powder and injection) in young buffaloes and cattle upto two years of age at Lahore and adjacent areas. The therapeutic trials were conducted on both sexes of buffaloes and cattle having moderate to heavy infection. The efficacy was evaluated on the basis of reduction in EPG (eggs per gram of the faeces) by using MoMaster technique.
Out of the total 300 faecal samples collected directly from the rectum of experimental animals, 128 were positive for G.I.T nematodes and incidence was found to be 42.66%. The eggs of different species of nematodes, as Neoscaris vitulorum, Haemonch, Cooperia, Ostertagia, Trichostrongylus etc. were identified from the faecal samples. It was observed that the incidence of G.I.T nematodes was 44.50% and 39.83% in buffaloes and cattle respectively.
Out of the 128 positive animals ninety animals were selected for the drug trials and divided into three groups of thirty animal each i.e groups A, B and C. The anthelmin tic efficacy of Levamisol Hcl oral and Levamisol Hcl injectable against G.I.T. nernatodes was observed by administering the drug to group A and B respectively and group C was kept as non-medicated control. The efficacy was determined on basis of reduction in number of ova count discharged in faeces post medication. The percentage efficacy observed on 14th day was 96. 71% and 97. 80% in buffaloes and cattle respectively, for Levamisole Hcl oral. The efficacy was 98.62% and 98.29% in huffa1oe, and cattle respectively for Levamisole Hcl injectable.
Availability: Items available for loan: UVAS Library [Call number: 0237,T] (1).
3.
Comparative Study Of Acaricides (Ivermectin & Asuntol) For The Treatment Of Mange Mites In Sheep
by Allah Diwaya Khan | Muhammed Sarwer Khan | Dr. Muhammad Ashraf | Muhammed | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1991Dissertation note: Ectoparasites are major problem creaters in the smooth rearing of sheep. Ainongs the ectoparasites mange mites are of prime importance as 'they damage skin, hide and wool etc. In the present study Iverinectin and Asuntol were used for the treatment of mange mites. A single subcutaneous injection of Ivermeotin 1% at dose rate of 1 nil/adult gave a cure of 80% adjudged on day 14 post treatment. A single spray of 0.1% solution of Asuntol could eliminate the condition in 65% of the clinical cases. On the same day in the animals which were kept as control (untreated), no spontaneous recovery was noted rather the condition aggravated.
Availability: Items available for loan: UVAS Library [Call number: 0238,T] (1).
4.
Study Of Coccidiosis In Different Age Groups & Estimation Of Haemaglobin, Pcv And Total Proteins In Camels
by Ashfar-ur-Rehman | Muhammed Sarwer khan | Dr. Muhammad Ashraf | Mubasher | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1991Dissertation note: The present study was conducted to find out the prevalence of coccidiosis in different age groups of camels and to estimate haemoglobin concentration, packed cell volume and total serum proteins in positive cases. For this purpose study was carried out on 300 animals of different age groups of camels (calves, young and adult) brought to Lahore abattoir for slaughtering during a period between June to August 1991. The investigation showed that out of 300 animals, 29 (9.66%) were positive for coocidiosis.
It was also observed that infection rate was higher in calves (25.86%) than in young (5.62%) and adult camels (6.09%). The study also indicated that the prevalence of coccidiosis remained as in the month of June (8.42%), July (9.60%) end in August (11.25%).
The present investigation revealed that an average haemoglobin concentration, packed cell volume and total serum protein were 9.2 ± 0..3g/100 ml, 35..27 ± 0.46% and 8.3 ± 1.0g/100 ml of positive animals respectively.. It was recorded that 19 animals showed decrease in haemoglobin, 6 showed increase in packed cell volume and 9 showed increase in total serum protein.
Availability: Items available for loan: UVAS Library [Call number: 0246,T] (1).
5.
Incidence Of Surra (Trypanasomiasis) & Estimation Of Blood Glucose Protein P.,C.V. Values In Camels Grought To Lahore Abbatoir
by Saleem Ahmad, S | Muhammed Sarwer Khan | Asif Rabbani | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.
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Publisher: 1991Dissertation note: Trypanosomiasis in camels caused by T. evansi occurs in both acute and chronic forms. In chronic forms huge production loss occur, i.e lower milk and meat yields. The present study had been designed to find out the incidence of the disease and estimation of blood glucose ,P.C.V. and protein level , it will eventually lead to the control of Trypanosomiasis.
For the incidence, blood samples were col- lected from Lahore abattoir and the presence of Trypa- nosome was confirmed by making smear from freshly collected blood samples from the ear vein.For the haematological study blood was collected from jugular vein in the glass tube . The values of protein , PC.V. and blood glucose was estimated by standard method.
Out of 500 samples 24 were proved to be positive i.e 4.80 % sample were positive.Whereas in the month of July 1991 it comes 4.16 %,In the month of Aug. 91 estimated as 5.58 % and during Sept. 91 was estimated as 4.30 %.
On examining the values of serum protein ,blood glucose and Packed Cell Volume ( P.C.V.) of the positive samples they showed slight increase in protein value ,decrease in glucose value and also reduction of P.C.V. values. Their mean values were calculated as 9.55 g/100 ml,29.07 mg/100 ml and 20.25 % respectively.
Availability: Items available for loan: UVAS Library [Call number: 0247,T] (1).
6.
Chemotherapy Of Fascioliosis With Nitroxynil And Estimation Of Serum Bilirubin & Sgot Levels In Sheep And and Goats
by Ayaz Wazir, Malik | Muhammed Sarwer Khan | Dr. Muhammad Ashraf | Muhammed | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1991Dissertation note: Fascioliasis is one of the major economically important diseases affecting a mass population of sheep and goats in Pakistan. The present study was designed to find out the prevalence of fascioliasis in N.W.F.P., and the serum bilirubin and serum glutamic oxaloacetic transaminase activities in sheep and goats before and after treatment with Nitroxynil.
In this study out of 240 sheep and 360 goats forty sheep (16.667.) and forty goats (11.117.) were found positive for fascioliasis, by applying direct smear and zinc sulphate floatation technique. The eggs per gram of faeces were done by Mc Master eggs counting technique. Serum samples of forty sheep and forty goats positive for fascioliasis and twenty sheep and twenty goats negative for the same were examined for bilirubin and SGOT activities before & after medication with Nitroxynil with a dose rate of 1 ml/20 kg body weight, sub cutaneously. The drug was highly effective in all the infected groups of the animals in eradication of fascioliasis. The efficacy of the drug in the form of the eggs per gram of faeces count was determined and was recorded as 83.907. in sheep and 85.977. in goats.
The mean serum bilirubin value of group "C6" was 0.24 mg/dl, which raised to 0.61 mg/dl, in group "A and to 1.19 mg/di in group "Be". Serum Bilirubin levels of group "Co" was 0.25 mg/dl at day zero while it was 0.69 mg/dl in group "Ag" and 1.09 mg/dl in group "Eg" animals on the same day.
The mean serum bilirubin values of group "C5 and Cg" remained unchanged after 14 days of treatment, while these values were 0.33 mg/dl and 0.33 mg/di in groups "As & Ag" respectively, after 14-days of medication. Similarly in groups "Ba & 8g" the reduction in serum bilirubin after 14- days post treatment also occured and the mean values were recorded as 0.62 mg/di and 0.52 mg/dl respectively.
Pre-medication mean serum glutamic oxaloacetic transaminase activities in group "C5 and Cg" were 40.14 units/mi and 40.15 units/mi respectively. The level of SOOT in these groups remained unchanged after medication, while serum 60T values were 86.95 units/mi and 80.77 units/mi in group "As and AQ" and were 96.75 units/mi and 106.27 units/mi in group "B5 and Bg" respectively, before treatment.
After 14 days of treatment with Nitroxynii the SOOT values of the above groups were significantly reduced, and the values recorded were 70.00 and 54.89 units/mi in "A5 and Ag" and 75.47 and 57.88 units/mi in group "Be, Bg" respectively.
Availability: Items available for loan: UVAS Library [Call number: 0328,T] (1).
7.
The Efficacy Of Ivomec Injection, A Broad Spectrum Anthelmintic, Against Gastro-Intestinal Nematodes & Lung Work In Sheep
by Karamat Ullah | Muhammed sarwer Khan | Dr. Muhammad Ashraf | Mubasher | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1991Dissertation note: A study was conducted to find outs the efficacy of a newly introduced, ((in Pakistan ) broad-spectrum anthelminitic injection i.e. ivomec (ivermactin H.S.D. Agvet) against the naturally infected sheep in District Guiranwala, Which were very heavily infected with G.I.T. nemtodes and lung worms. The animals were emaciated, in Diarrhoe-al condition, rough wool coat and with cough. (confirmed by feacel egg and larval count examinations).
In total 90 sheep were rendemly selected for this study. They were divided into three equal group each containing 30 animals namely A, B. & C. (Group A positive for G.I.T. nematode infection, group B positive for lung worm infection and group C kept as non-medicated infected control). Group C was further divided into group C1, kept as control against the nematode infected group & Group C2 kept as control against the lung worms infected group.
The drug was used according to the manufacturer recommended dosage i.e. 0.2 mg/kg body weight injection by sub-contaneous route. The drug revealed a high efficacy (100%) against the G.I.T. nematodes and lung' worm infection. The egg counting and larval of lung worms counting was performed on the 0, 3rd, 7th and 10 day of the treatment. The E.P.G. and larval count was 0 at 3rd, 7th and 10th day of treatment which indicated that this drug was 100% effective against- G.I.T. nematodes and lung worms.
A 0.75 kg weight gain was seen in the treated groups while animals of control groups reduced weight. No side effects of medicine were recorded during the experiment.
Availability: Items available for loan: UVAS Library [Call number: 0329,T] (1).
8.
Comparative Study Of Oral And Parenteral Therapies Of Experimentally Induced Spirochaetosis In Broiler Chicken
by Shaif abdo Salem | Dr. Muhammad Sarwar Khan | Dr. Muhammad | Dr. Muhammad Ather Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1993Dissertation note: With rapid progress in commercial poultry farming the need to control poultry diseases, spirochaetosis is responsible for heavy economic losses with a mortalitry rate of 60 to 80 percent. (Mc Neil 1949).The disease is caused by Borrelia anserina and is of worldwide in distributed,whereever the tick Argas Percicus, which acts as the intermediate host is present.
This disease has characteristic symptoms of pyrexia, weakness,drowziness, anaemia, diarrhea, emaciation,paralysis, and finally death (Marcos et al 1946) The bfrdswhich survive remain weak,ariaemic, emaciated, and do not thrive well.This disease is of great economic importance in the poultry industry and it causes great financial ioss.It is therefore,inspective that an effective and economical treatment be devised to eradicate this problem.
This experiment.was conducted on 120 A grade day old chicks,which were reared under ideal hygienic condition.At the age of four weeeks the birds were divided into six equal groups, A, B, C, D, E and F with 20 bires in each respective group:
Group A (Non-infected , non-medicated
B (Infected and non-medicated)
C (Infected and medicated with Pencillin)
G (parenterally)
D (Infected and medicated with oxytetracyclin parenterally)
E (Infected and medicated with oxytetracyclin orally)
F (Infected and medicated with Amoxyclin Clomaxal orally)
Except for group A which was the control, all the remaining five groups showed the typical signs of the disease after 48 hours of in oculatiori.
In Group 13, the mortality rate was 40% ,Group C had a 20% mortality rate at 96 hours.Cure was l0O%.Group D had a 25% mortality and 100% cure at 96 hours post inoculation.Group E had a 30% mortality rate which was the highest of all the groups and curative rate 80%.The Group F had a 15% mortality which was the lowest record in all the six groups.It had 100% cuire at 96 hours.
From the results of this experiment it could be concluded that the 1\moxycillin (Clomoxal) was drug of choice. Penicillin G and Oxytetracycline (Terramycin orally ) showed the poorest results.
Availability: Items available for loan: UVAS Library [Call number: 0364,T] (1).
9.
Study On Fasciioliasis With Estimation Of Haemoglobin & Total Serum Proteins In Camels Brought To Lahore Abbatoir
by Maj. Naeem Ahmed Janjua | Dr. muhammad Sarwar Arkhan | Dr. Ch | Dr. Muhammad Athar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1993Dissertation note: The present study was conducted to find out the prevalence of fascioliasis in different age groups of camels and to estimate the haemoglobin concentration and total serum protein levels in positive cases and also equal number of negative cases. For this purpose study was carried out on 512 camels of different age groups (calve, young and adult) brought to Lahore Abattoir for slaughtering during a period between May to July 1993.
The investigations revealed that out of 512 camels, .50 (9.76%) were positive for fascioliasis. It was observed that infection rate was higher in adult ( 10.68%) than in young (8.98%) and calf camels (7.27%). The study also indicated that the prevalence qf fascioliasis in months of May June and July was 9.20%, 10.55% and 9.46% respectively.
The present investigations reveled that an average haemoglobin concentration was 7.5 g/100 ml with a range of 4.1 - 10.3 g/100 ml (Table 8) and total serum protein level on average was 7.6 g/100 ml of positive camels with a range of 5.1 - 9.6 (Table 7).
The negative blood samples of 50 camels were also examined for the estimation of haemoglobin concentration and total serum protein levels. The mean values of haemoglobin concentration indicated by the studies was 13.1 g/100 ml ranging between 12.2 - 14.1 g/100 ml (Table 12 and 13). Total serum protein mean value revealed by the study was 6.7 g/100 ml and it ranged between 6.2 - 7.4 g/100 ml (Table 14 and 15).
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10.
Effect Of Experimentally Induced Coccidiosis On Some Blood Parameters And Its Treatment With Embazin & Coxistac In Quails
by Anwaar Hussain, Syed | Dr. Muhammad Sarwar Khan | Dr. Asif | Dr. Muhammad Athar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1993Dissertation note: This project was designed to study the effects of experimentally induced coccidisis on some blood parameters and its treatment with Embazin and coxistac in Quails. For this purpose 300 day old quail chicks were obtained from a local hactchery and raised under standard, controlled coccidia free conditions. A commercial coccidiostat free feed was provide. At the age of 21 days. birds were divided into 4 groups comprising 60 birds each and shifted from brooder into a multistorey cage and grouped as tinder:Group A (60 quails) Infected and medicated with Embazin.
Group B (60 quails) Infected and medicated with Coxistac.
Group C (60 quails) Infected and non-medicated.
Group D (60 quails) Non-infected-Non-medicated.
Birds of group A, B and C were infected with 1 ml of coccidial inoculum having 50,000 sporulated oocysts given directly into crop. Group D was kept as control group. On fourth day post infection birds of all infected groups showed disease symptoms and at that time groups A and B was medicated with Embazin and Coxistac respectively. Four samples of blood and faeces were collected from each group on zero day, 5th day and 9th day of medication. In groups A and B Haemoglobin and Total Erythrocytic Count was lowered on 5th day and then increased on 9th day of medication oocyst count was Nil on 9th day of medication in group A and 92.30% reduction percentage was there is in group B. Haemoglobin and Total Erythrocytic Count decreased in group C upto 9th day ofmedication but oocyst count increased in this group. Increase percentage was 7.14% on 5th day and 14.28% on 9th day of medication. In group D Haemoglobin andTotal Erythrocytic Count remained almost constant and oocyst count was found Nil throughout the experimental period.
The best feed conversion Ratio of 3 was recorded in group D whereas group "C" which was infected but not treated showed worst feed conversion ratio i.e. 4. Group A & B revealed intermediate F.C.R. of 3.6 and 3.8 respectively.
Hishest mortality of 33.33% was recorded in group C, 13% in group B and 11.66% in group A. In group D mortality was Nil. From the findings of study it was concluded that Embazin was drug of choice for the treatment of coccidiosis in quails.
Availability: Items available for loan: UVAS Library [Call number: 0372,T] (1).
11.
Efficacy Of Triclabendazole Against Fascioliasis In Sheep And Goat Under The Field Conditions
by Haleem Hasan, Shah | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahmad | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1994Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0374,T] (1).
12.
Comparative Efficacy Of Nitrofurans, Sulphadimidine & Monensin Against Coccidiosis In Sheep & Goats Under Field Conditions
by Anselm Lewis, Khokhar | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahmad | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1993Dissertation note: The present work was designed to study the comparative efficacy of Nitrosol, Suiphadimidine and Monensin against naturally infected sheep and goats with coccidiosis. Forty sheep and forty goats (infected) were selected and divided into four groups each i.e. S1, 2, S3, 84 and G, 02, G, 04 respectively. The animals of groups S and were treated with nitrosol 15 mg/kg body weight, S2 and 02 with sulphadimidine 140 mg/kg body weight, S3 and G with monensin 5 mg/kg body weight daily for five days. The sheep and goats in groups S4 and G4 were not medicated and served as control. The oocyst count per gram of faeces were compared on the 7th, 15th and 21st day of post medication.
The oocyst count was reduced in groups S, S2, and S3 by 95.79%, 99.53% and 85.81% and in groups 1, G by 95.97%, 99.60% and 85.01%. The oocyst count in infected untreated control groups S4 and 04 increased.
All the three anticoccidials tested gave appreciable response in reduction of oocyst counts but suiphadimidine was found to be the best amongst the three drugs. Nitrosol proved to be the 2nd whereas monensin proved to be the third in efficacy against coccidiosis in sheep and goats. No side affects of these drugs were observed) it is suggested that further research should be planned to test the efficacy of other anticoccidial drugs like lasalocid, amprolium colpidol, robenidine coxistac etc. under local conditions to select new drugs against coccidiosis in sheep and goats.
Availability: Items available for loan: UVAS Library [Call number: 0376,T] (1).
13.
A Profile Of Serum Albumin, Globulin Ratio, Total And Differential Leukocytic Count In 6-10 Months Old Buffalo Calves
by Khalid Hameed, Chughtai | Dr. M. Athar Khan | Dr. Muhammad | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1993Dissertation note: One hundred arid fifty samples of each coagulated and non- coagulated blood were collected from buffalo calves (100 healthy and 50 diseased buffalo calves) of 6 to 10 months of age
The samples were analysed for total serum protein, serum albumin, serum globulin and total leuckocytic count by applying Biuret method with commercial kit (Proti) using a spectrophotorneter, and standard techninques of Cole for total leuckocytic count.
The mean total serum protein values for healthy buffalo calves of 6 to 10 months of age were observed between 5.4 19 to 7.468 g/dl. A gradual increase in totalserum protein levels was observed with an increase of age. The total serum protein values for diseased buffalo calves varied as compared to healthy calves. A decrease in mean total serum protein levels. (6.189) was associated with malnutrition, diarrhoea, fever and Fasciollosis as compared to the mean total serum protein levels in healthy calves (6.404). An increase in total serum protein level (5.793 g/dl and 7.576 g/dl) were observed during 6th and 10th month of age as compared to healthy calves (5.419 g/dl and 7.468 g/dl). This increase was due to dehydration.
A gradual increase in mean serum Albumin levels 2.458 to 3.449 g/dl was observed in healthy buffalo calves of 6 to 10 months of age. A significant (P < 0.05) difference in serum albumin values was observed in all age groups both in healthy and diseased buffalo calves. A decrease in serum albumin levels (2.516) was observed In calves suffering from malnutrition, diarrhoea, fever and fasciollosis.
The mean serum globulin levels observed in healthy buffalo calves of 6-10 months of age was observed between 3.218 to 4.144 g/dl. These serum globulin levels showed a gradual increase with increase in age of buffalo calves. An increase in serum globulin level (3.898) was observed in diseased buffalo calves as compared to healthy calves in all age groups. The diseased calves were saffertig from malnutrition, diarrhoea, fever and fasciollosis. A significant (P <0.05) difference in serum globulin values was observed in age group of 6th month of age in healthy and diseased buffalo calves whereas in all other groups it was non-significant. The mean total leukocytic count hveIs observed in healthy buffalo calves of 6 to 10 months of age ranged between 8.765 to 9.655x103 microliter. A gradual increase iii mean total leukocytic count (9.26) x 103 microlitre was observed with an increase of age in healthy buffalo calves of 6 to 10 months of age. An increase in total leukocytic count level (10.966) was observed in diseased buffalo calves as compared to healthy calves in all age groups. A significant (P <0.05) increase in total leukocytic count was observed in calves suffering from diarrhoea, fever and fasciollosis.
From the above mentioned facts it was concluded that these blood parameters are important tools in investigation/diagnosis of many diseases. These parameters enable us to understand and compare the leveI of humoral and cellular defensive components in a natural farm co idition in buffalo calves of 6 to 10 months of age.
Availability: Items available for loan: UVAS Library [Call number: 0379,T] (1).
14.
Efficacy Of Ivermectin (Ivomec) Against Mange Mites And Warbles In Goats
by Saleem Qasur | Dr. Muhammad Sarwar Khan | Dr. Muhammad | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1994Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0380,T] (1).
15.
An Epidemiological & Haematological Correlation Between Healthy & Tuberculous Indigenous Birds
by Azeem Ijaz | Dr. Muhammad Athar Khan | Dr. Asif | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1994Dissertation note: A total of 250 desi birds, selected randomly, from different villages of district Lahore, were divided into two groups. The group-I composed of 125 apparently healthy birds whereas 125 apparently weak and emaciated birds were present in group-IT. Avian tuberculin test was employed to diagnose the tuberculosis. A 0.1 ml of avian tuberculin (MCSM) procured from VRI, Lahore, was injected into left wattle whereas right wattle was kept as uninjected control and test was read after 48 hours. Only 6 birds (2.4%), all belonged to group-IT, were found tuberculin positive. Haematological studies of these six tuberculin positive birds were carried out along with 10 healthy desi birds for comparison. There was decrease in erythrocytic count (EC), haemoglobin value (Hb) and packed cell volume (PCV). The average values of EC, Hb and PCV of infected birds were 1.94x106/µ1, 8.86 g/dl and 22.69% respectively. On the other hand, leukocytic count (LC) was increased and found to be 37.33x10/il on average. A significant change in differential leukocytic count (DLC) was also observed with an increase in the proportion of polymorphs and monocytes and fall in lymphocytes. The lymphocyte to heterophils ratio was the inverse of that in healthy birds. On post-mortem, a large number of tubercles of varying size were noticed on liver, spleen and intestines. No birds showed lung lesion except one.
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16.
Bioavailability Of Gentamicin In Male Buffalo Calves
by Hasan Raza, S | Dr. Muhammad Sarwar Khan | Dr. Muhammad Ashraf | Prof. Dr. Saghir | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1994Dissertation note: The bioavailability and pharmacokinetics of Gentamicin sulphate were investigated in the same 20-male buffalo calves heal thy after intravenous administration and after intramuscular administration. The blood samples were collected at various time intervals following administration of single dose of 4 mg/kg. The concentrations of Gentamicin in serum samples were determined according to the microbiological assay described by Arret (1971). The plasma concentrations of gentarnicin at different time intervals after injections were plotted on semi-logarithmic graph paper. The bioavailability and pharmacokinetics parameters were calculated according to the method described by Gibaldi (1984). Results were expressed as mean ± SD.
The peak concentration of 11.273 ± 0.4976 µg/ml reached in 31.092 ± 1.217 minutes after intramuscular injection. Keeping intravenous as standard the relative bioavailability after injection was 82.5%.
The half-life was 97.29 ± 5.259 minutes after I/v injection mean ± SD, volume of distribution was 202.36 ± 8.486 ml/kg/ The volume of distribution at steady stage (Vdss ) was 214.67 ± 20.99 ml/mm. The total body clearance of gentamicin was 1.7382 ± 0.0738 ml/kg.
Pharmacokinetics parameters of gentamicin were seemed to be independent of rout of administration at the dosage level applied.
The pharmacokinetics evaluation by compartmental method and non-compartmental method was not found significantly different.
Availability: Items available for loan: UVAS Library [Call number: 0390,T] (1).
17.
A Study On The Prevalence Of Mange In Camels And Its Effects On Some Blood Parameters During Winter Months
by Bashir Ahmad | Dr. Muhammad Sarwar Khan | Dr. Khalid | Dr. Muhammad Athar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1993Dissertation note: Camel is a versatile creature of the Nature. Its population in Pakistan is 9,58,047 heads. Its importance is obvious from the facilities which it provides to the mankind e.g. transportation and ploughing facilities, lifting of water and pulling of carts, provision of milk meat and earning of foreign exchange. But. on the other hand, camel is ignored in provision of better managernental facilities due to which it is facing many disease problems. Similarly, camel is also ignored by our scientists and a little research work has been done on camel in the world.
Keeping in view all these factors, this project was designed to see the prevalence of mange in camel. This study also include haematological changes in camel blood suffering from mange.
This study was conducted during winter months of the 1992 at Lahore abattoir. For the prevalence of mange, 150 camels suspected for mange were selected and their skin scrapings and blood was collected.
Skin scraping was examined with the help of microscope at Laboratory of Medicine Section, College of Veterinary Sciences, Lahore. During the study 19 camels out of 150 were found positive to mange and this is calculated as 12.66%.
Regarding the 2nd portion of the study, blood of 19 mange infected cases were analysed for total leukocytic count (TLC), differential leukocytic count (DLC) and erythrocytic sedimentation rate (ESR). At the same time blood of 19 mange free camels was also examined and it was found that due to mange infection, TLC values were increased. In case of DLC, Eiosinophils and lymphocytes showed increase in their number. ESR was also increased due to infection of mange in camels.
Availability: Items available for loan: UVAS Library [Call number: 0403,T] (1).
18.
Prevalence Of Lungworm Infestation (Dictycaulus Spp.) And Its Effect On Some Blood Parameters Of Camels During Months Of October December.
by Aslam, M | Dr. Muhammad Sarwar Khan | Dr. Asif | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1995Dissertation note: Camel is a versatile creature of the nature. Its population in Pakistan is 9,58,047 heads. Its importance is obvious from the facilities which it provides to the mankind e.g. transportation and ploughing facilities, lifting of water and pulling of carts, provision of milk meat and earning of foreign exchange. But on the other hand, camel is ignored in provision of better managemental facilities due to which it is facing many disease problems. Similarly, camel is also ignored by our scientists and a little research work has been done on camel in the world.
Keeping in view all these factors, this project was designed to see the prevalence of lungworm infection in camel. This study also included haematological changes in camel blood suffering from lungworm infection.
This study was conducted during the months of OctoberDecember, 1993 at Lahore abattoir. For the prevalence of lungworm infection, 150 camels suspected for lungworm infection
were selected and their faecal and blood samples were collected.
Regarding the prevalence of lungworm infection through faecal examination the results of present investigation show that occurrence of lungworm infection in camels is 6.00%, i.e. 9 camels out of 150 suspected were found positive.
The mean values of haematological examination were observed i.e. Total leukocytic count (31.62 thousand/cm.mm), Differential leukocytic count - Neutrophils 67.88%, Eosinophils 28.77%, Basophils 3.66%, Lymphocytes 65.88%, Monocytes 5.55%, and ESR 12.20 mm/hour.
Blood of camels negative to lungworm infection showed total leukocytic count mean value 19.30 thousand/cu.mm, Differential leukocytic count - Neutrophils 47.00%, Eosinophils 8.88%, Basophils 1.88%, Lymphocytes 38.55%, Monocytes 4.22% and ESR 1.85 mm/hour.
Availability: Items available for loan: UVAS Library [Call number: 0405,T] (1).
19.
Epidemiological, Serological And Hematological Investigations In An Out Break Of Bovine Viral Diarrhoea And Foot
by Ghaffar Khan, A | Dr. Muhammad Athar Khan | Dr. Muhammad | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1995Dissertation note: After an outbreak of a vesicular disease in Lahore District a demoninator based active surveillance was conducted in four villages. During and after the epidemic and the homesteads were visited and interviewed from door to door. The total number of animals kept by the farmers (N = 1537) and the affected number of animals (n= 1384) by age, sex and species were enquired from the farmers and recorded on a questionnaire proforma. The clinical signs of the affected animals and their sequence were recorded.
Epidemiological investigations revealed that morbidity rate of 66.94% (n=867/1537) was higher in buffaloes than cattle which was 48.34% (n=117/242). Young animals of both species were more susceptible than adults. Morbidity rate in young cattle was 50.64% (n=39) in 77 animals but in case of adult cattle amongst the total population of 165 morbidity rate was 47.27% (n=78). In case of young buffaloes 290 (69.37%) out of 418 animals while in case of adult buffaloes morbidity rate was 63.51% (557/877). Case fatality rate was observed higher 42.85% (363/847) in buffaloes than the cattle which was 26.65 % (37/117). Frequency of clinical signs observed was found as depression (63.30%), mucosa diffusely red (61.87%), anorectic (61.48%), muzzle hyperimic encrusted (61.09%), erosions (58.49%), laminitis (56.73%), temperature 101-105°F (54.26%), drooling (53.35%), shivering (44.82%), mistitis (38.51%), temperature 105-107°F (6.18%), polypnea (5.79%), temperature 101-103°F (4.35%), cough (3.38%), diarrhoea (2.40%), subnormal (0.71%) and abortion (0.65%).
In this project 160 animals affected from the disease, 80 of each species, were selected for hematological and serological investigations. Forty healthy animals were observed as control.
Blood samples from the affected Buffaloes were tested for the total erythrocytic count (TEC), total leukocytic count (TLC), packed cell volume (PCV), erythrocyte sedimentation rate (ESR) and differential leukocytic count (DLC) i.e. neutrophils, lymphocytes, eosinophils, monocytes, basophils and their average values were observed as 3.56 ± 0.31 x 106/ul (5.18 x 106/ul), 4.90 ± 1.22 x 103/ul (6.45 x 103/ul), 26.59 ± 2.14% (29.31%), 10.13 ± 0.92 mm/Ist hr. (4.56 mm/Ist hr.), 30.54 ± 1.07% (32.55%), 59.18 ± 1.03% (56.16%), 1.78 ± 0.22% (2.41%, 5.92 ± 0.52% (4.51%), 0.29 ± 0.01% (0.48%) respectively.
Blood samples from the affected cattle were tested for the TEC, TLC, PCV, ESR and DLC i.e. neutrophils, lymphocytes, eosinophils, monocytes, basophils and their average values were observed as 5.76 ± 0.32 x 106/ul (7.24 x 106/ul), 6.73 ± 0.92 x 103/ul (7.99 x 103/ul), 31.49 ± 1.59% (33.90%), 9.32 ± 1.32 mm/Ist hr. (3.16 mm/Ist hr.), 31.08 ± 1.09% (34.82%), 45.00 ± 1.05% (41.31%), 0.33 ± 0.04% (0.63%), 9.16 ± 0.46% (7.86%), 0.33 ± 0.03% (0.63%) respectively.
Serum samples from the affected buffaloes were tested for the total serum protein (TSP), serum albumin and serum globulin and their average values were came as 5.97 ± 0.56 g/dI (7.72 g/dI), 2.80 ± 0.37 g/dl (3.55 g/dll), 2.40 ± 0.95 g/dl (4.17 g/dl) respectively.
Serum samples from the affected cattle were tested for the TSP, serum albumin and serum globulin and their average values were observed as 6.43 ± 0.45 g/dl (7.58 g/dl), 2.67 ± 0.35 g/dll (2.32 g/dl), 2.67 ± 0.52 g/dI (4.26 g/dll) respectively.
Agar gel immunodiffusion test used for the antibodies detection was found positive for foot and mouth disease (FMD). Typographically two strains O (42.50%) and Asia-I (29.38%) were isolated out of 160 samples.
A total loss of Rs. 5.286 millions due to FMD in cattle and buffaloes was estimated in the four villages.
Note: Values in parenthesis are normal/standard for the respective parameter.
Availability: Items available for loan: UVAS Library [Call number: 0412,T] (1).
20.
Effect Of Hydatid Cyst On Different Blood Components In Camels Of Different Age Groups
by Hameed ur Rehman | Dr. Muhammad Sarwar Khan | Dr. Khalid Pervaiz | Dr. Shakil | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1995Dissertation note: The present project was designed to find out the prevalence of hydatidosis in different age groups of camels and to see its effect on some blood parameters (TEC, Hb, PCV) and also to examined the same blood parameters of control groups. For this purpose study was carried out on 300 camels of various age groups (2-3 years, 3-5 years, and above 5 years) brought to Lahore abattoir for slaughtering purposes during the period from July 1994 to September 1994.
The results showed that out of 300 camels, 189 (63%) were positive for hydatidosis. It revealed that infection rate was higher in Group-Ill (above 5 years) 70%, than in Group-I (58%) and Group-Il(61%). The study also revealed that the prevalence of hydatidosis was 67.68% in July, 54.9% in August and 66.67% in September
The present investigation also showed that a mean of total erythrocyte count was 8.667 million/microliter with range of 6.00 million/microliterto 11.101 million/microliter, Haemoglobin concentration was 10.00 g/100ml with a range of 6.3 g/100 13.1 g/l00ml and mean of packed cell volume was 31.7 with a range of 20.00% to 39.00%.
The control blood samples of 189 camels showed mean of total erythrocyte was 9.721 million/microliter ranging from 6.32 million/microliter to 12.92 million/microliter, mean of haemoglobin concentration was 11.5g/100ml with a range of 7.3 g/100ml to 14.4g/100ml and packed cell volume was 33.4% with a range of 22.00% to 40.7%
Availability: Items available for loan: UVAS Library [Call number: 0413,T] (1).
21.
Comparison Of Single And Stack Pinning Techniques For Mid Shaft Femoral Fracture In The Dog
by Kamran Akhtar | Dr. Mazhar Iqbal | Dr. Muhammad Arif | Dr. S | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1995Dissertation note: The incidence of femoral fracture is higher than that of other long bones in clogs. Immobilization of Fernoral fractures by external method of fixation is almost impossible due to angulation of the hind limbs, thickness of thigh musculature and difficulty of controlling motion in the hip joint. This type of orthopeadic ailment can he handled successfully with hone splintage principle which, includes the use of compression plates, cerciage wires, and intrarneclullary pins. In this project stack pinning and single intramedullary pinning with hemicerciage wires were used to treat midshaft transverse femoral fractures n the clog. The procedure was conducted on 20 mongrel dogs of either sex, divided into two groups of 10 clogs each .
In group I the surgically created mid shaft femoral Fracture was immobilized using single intramedullary pin with hemicerclage wires. Whereas in group II the fracture was immobilized with stack pinning. First pin was introduced in a retrograde and the second pin in a normograde fashion. All the dogs were kept in Kennels For a period of sixteen weeks and results were collected on the basis of clinical and radiographic evulations. All the clogs were euthanisecl at the end of experimental period and operation sites were explored to find out the gross changes
The analysis of the results clearly indicated that intramedullary pinning with hemicerclage wires was a better choice over stack pinning for repairing mid shaft transverse femoral Fractures.
Availability: Items available for loan: UVAS Library [Call number: 0415,T] (1).
22.
Effect Of Glucocorticoids Alongwith Antimicrobial Drugs Against Haemorrhagic Septicaemia In Buffalo
by Ramzan, M | Prof.Dr.Muhammad Ashraf | Dr. Khalid Pervaiz | Dr. Muhammad | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1995Dissertation note: Two long acting antibiotic preparations of oxytetracycline and amoxicillin were used in these trials against Haemorrhagic Septicaemia, singly and alongwith a combination of synthetic glucocorticoids (Dexamethasone and prednisolone).
Eighty buffalo calves suffering from Haemorrhagic Septicaemia were selected and treated under field conditions. Weighted clinical score was recorded before and after treatment in each case, on the basis of severity of clinical symptoms. Reduction in this score and recovery or death of animal was also noted.
It was concluded that amoxicillin was more effective than oxytetracycline and the addition of glucocorticoids reduced the convalescence period and also increased the survival rate. Therefore long acting amoxicillin alongwith Dexamethosone and prednisolone is recommended as the successful therapy for Haemorrhagic septicaemia.
Availability: Items available for loan: UVAS Library [Call number: 0420,T] (1).
23.
Evaluation Of Uretero Jejunocolostomy For Urinary Diversion In The Dog
by Aneeta Hussain | Dr. Mazhar Iqbal | Dr. Muhammad | Dr. Muhammad Arif Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1995Dissertation note: Urinary diversion is the procedure adopted for urine expulsion in the most natural way, in the absence of the urinary bladder. In the beginning of the twentieth century many surgeons of human side as well as veterinarians used intestines for performing urinary diversion. They adopted many methods for this purpose but only a few were found to be successful. These procedures were used to relieve the animal from malignant bladder carcinomas, severe damage of bladder and urethra during accidents, and extrophy of urinary bladder etc. These diseases mostly cause urinary discomfort, incontinence of urine and painless heamaturia and cystectomy becomes a necessity.
During this study fifteen healthy dogs of either sex were used. Laparotormy was performed under aseptic precautions. The small intestine was exteriorized through. the incision and the terminal portion of jejunum was identified. A 6-8 cm portion of the jejunurn was selected and milked to clear it of from the feacal materials. This portion was isolated from rest of the intestinal tract with the Doyen's intestinal clamps and was cut off with its mesenteric blood supply remaining intact. The continuity of the small bowel was restored by end to end anastomosis. The vent in mesentery was closed by simple continuous sutures. The isolated Jejunal segment was wrapped in a piece of gauze soaked in normal saline.
The urinary bladder was emptied in females by gentle digital pressure and in males by mean of a disposable syringe. The ureters were amputated obliquely down to the trigone area and bladder was excised. Afterwards one end of the Jejunal segment was closed by lambert sutures. A small hole was created on the right side at the upper third portion which cut through the first three layers. From this hole a 2 cm long submucosal tunnel was created going towards the open end of the segment. The cut end of the ureter was sutured to the mucosa of the Jejunal segment using 3/o prolyene simple interrupted sutures. On the left side of the segment the other ureter was implanted similarly.
A longitudinal incision equal to the diameter of jejunal segment was made at the antimesenteric border of the distal portion of colon. The open end of jejunal segment was implanted here using 3/0 chromic catgut via side to end anastomosis with simple I nierrupted crushing sutures, thus creating an intestinal bladder. Finally the abdomen was closed in routine manner. It was concluded on the basis of this study that:
1. Viable segment of small bowel with blood and nerve supply intact can be used as a bladder.
2. Voiding occurs in the most natural possible way without any need of an external reservoir.
3. There was no ascending infection, so kidneys remained normal.
4. Use of antibiotics for rest of the life was not needed.
The successful attempt of making a new bladder strengthened the belief in cases where there was no other way of saving the animal's life except surgical intervention. So the veterinarian should involve himself with the core of his heart in the operative procedure with the aim of achieving good results. Whether he loses or gains, he must have a satisfaction of being loyal to his profession.
Availability: Items available for loan: UVAS Library [Call number: 0423,T] (1).
24.
Prevalence And Chemotherapy Of Coccidiosis In Sheep And Goats And Its Effect On Certain Blood Parameters
by Nasir Ali, Faridi | Dr. Muhammad Sarwar Khan | Dr. Khalid Pervaz | Dr. Mubasher | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1995Dissertation note: This project was designed to find out the prevalance and chemotherapy of coccidiosis in sheep and goats and its effect on certain blood parameters like Haemoglobin, TLC, DLC, Glucose,and Total Serum Protein.
Two drugs namely suiphadimidine and suiphaqunoxaline were used in this research project. For this purpose 60 animals(i.e sheep and goats) were taken and divided into 3 groups(A,B and C) containing 20 animals each(i.e 10 sheep and 10 goats). Group A was again subdivided into two subgroups Ag & As containing 10 animals each(i.e 10 goats and 10 sheeps) were treated with sulphadimidine.Group B was again subdivided into two subgroups Bg & Bs containing 10 animals each(i.e 10 goats and 10 sheeps) were treated with suiphaquinoxaline. Group C was again subdivided into two subgroups Cg & Cs containing 10 animals each (i.e 10 goats and 10 sheeps) were kept as infected non.medicated control.
The efficacy of drugs were determined on the reduction of OPG in faeces.
From the results it is find out that the average OPG on zero day of medication in groups i.e Ag,As & Bg,Bs were 75100, 72200, 60800 & 67200 respectively.The average reduction of OPG on 10th day of medication in groups i.e Ag,As & Bg,Bs were 300,340,120 & 280 respectively.The OPG of control groups were increased on the subsequent days.
The average Haemoglobin on zero day of medication in groups Ag,As,& Bg,Bs were 6.53,8.02,6. 89 & 7.93 respectively The average Haemoglobin on lOtti day of medication in groups Ag,As,Bg,Ss were 8.628.80, 9.44 & 8.78 respectively.The Haemglobin of the control groups were decreased on subsequent days. Average TLC on zero day of medication in groups Ag,As,Bg,Bs were 16.50 ,16.50 & 15.50,19.50.Average TLC on 10th day of medication in groups Ag,As & Bg,Bs were 14.50,12.90 & 13.60,13.50 respectively.The TLC of control groups were increased on the subsequent days.Average DLC on zero day of medication in groups Ag was 49.40,68.00,7.00 11.10 & 17.50 in group Bg was 51.20 ,70.30,6.90, 12.20 & 19.40 in group As was 50.20,70.20,8.00,12.00 & 18.50 in group Bs was 50.40.71.60,6.10,17.20 & 18.40 .Average DLC on 10th day of medication in groups Ag was 48.40,67.00,7.00 11.10 & 17.50 in group Bg was 50.20 ,69.30,7.10,12.20 & 19.40.ln Group As was 49.40,69.10,8.00,12.00 & 18.50 in group Bs was 49.40,70.60,6.10,17.20,18.40.DLC of the control groups were incresed on the subsequent days. Average Blood Glucose on zero day of medication in groups Ag,As,Bg,Bs were 24.30, 31.30 & 29.30, 35.50 respectively.Average Blood Glucose on 10th day of medication in groups Ag,As,Bg,Bs were 37.00, 42.40, 42.80, 45.00. Blood glucose in control were decreased on the subsequent days. Average Total Serum protein on zero day of medication in groups Ag,As & Bg,Bs were 3.52,4.25,3.93,4.18. Average Total Serum protein on 10 th day of medication in groups Ag,As,Bg,Bs were 4.89,5.56 & 5.43,5.57 respectively.The total serum protein in control groups were decreased on the susequent days.
Availability: Items available for loan: UVAS Library [Call number: 0426,T] (1).
25.
Comparative Evaluation Of Esophagotomy In The Equine With And Without Pharyngostomy Tube
by Safdar Hamid, Bhatti | Dr. Mazhar Iqbal | Dr. Mohammad | Dr. Muhammad Younis h | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1995Dissertation note: The esophagus is one of the important parts of gastrointestinal tract of the animals. It is a specialized organ, serving to carry food from pharynx to the stomach. There are so many anomalies associated with esophagus like obstruction due to foreign bodies, tumors, strictures, diverticula and stenosis. Esophageal obstruction (choke) in equines can occur as a result of food impaction, orally administered caustic or corrosive medicinal agents and trauma to the neck. Choke is most commonly caused by food impaction, which can result in circumferential mucosal damage and subsequent esophageal strictures. The mega-esophagus may lead to pneumonia as a result of aspiration of ingesta. The diagnosis is based on the history and clinical signs. In all such cases esophagotomy is the only solution to the problem, as the conservative treatment does not help the animal.
To carry out this experimental study 15 donkeys were divided into four groups. Group-I comprised of seven animals, Group-IT and III had three animals each and group-TV consisted of two animals. In group-I, the esophagus was incised longitudinally and closed in two layers. After closure of esophagotomy the pharyngostomy tube was passed for feeding purpose. In group II and III the esophagotomy procedure was the sam as in group I, but the animals were fed without pharyngostomy tube after surgery. The animals of group II, were kept on intravenous therapy for the first 72 hours and then shifted to the liquid diet per orum. Whereas the animals of group III were kept on liquid diet for the first seven days and then to the pelleted diet till 15th post-operative day. From then onward they were fed solid food orally. The esophagotomy incision in group IV was not sutured. These animals acted as control and were allowed to eat solid food orally from the very first post-operative day. The animals of each group were closely watched during the experimental period for seroma, leakage and infection. The tabulated and graphic results indicated that the animals of group II showed better results than the animals of group I, III and IV because:
i) The esophagotomy incision healed through first intention.
ii) No signs of dehiscence or leakage were noticed.
iii) As the animals were kept on parenteral therapy for the first 72 hours, it helped in good mucosal healing and no leakage was seen.
iv) The necropsy finding revealed, that the mucosal and muscular layers healed excellently.
Availability: Items available for loan: UVAS Library [Call number: 0427,T] (1).
26.
Effect Of Experimentally Induced Coccidiosis On Some Blood Parameters And Its Treatment With Three New Anticoccidial Drugs In Broilers
by Arshad Latif Arshad | Dr. Muhammed Sarwer Khan | Dr. Haji Ahmed | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1995Dissertation note: One hundred and fifty day 01(1 broiler chicks were obtained from a local hatchery. They were reared upto day 26. All the birds were given feed having no coccicliostat.
At the age of 26 clays the birds were divided into five groups A, B, C, D and E. The D and B were control groups. The test groups were infected with 75000 sporulated oocysts On 26th day of age, group D was infected and non medicated while group E was kept non infected and non medicated. The group A, B and C were treated with clopidol, monensin and salinomycin respectively after the appearance of clinical symptoms.
The total oocyst counts in all groups on zero day of infection were nil and on 1st, 5th and 9th day of medication, groups A, B, C, D showed 25800, 20400, 23800, 197500 oocysts counts respectively, while group B examined nil being control non infected group.
The mortalities observed in groups A, B, C, D and E were 6, 2, 3, 8 and nil while percent mortality was 20%, 6.66%, 10%, 26.66% and 0.00%. In treated groups, monensin showed least mortality.
The feed intake and feed conversion of groups A, B and C were almost equal. While group D (infected and non medicated) was relatively poor. As far as group E (non infected and non medicated) is concerned it showed better results.
In haematological studies the average values of haemoglobin levels, erythrocytic count and total serum protein were lower post infection as compared to the respective control group E (non infected and non medicated). The total leukocytic count was increased in all groups as compared to group E (non infected and non medicated). The differential leukocytic count, the lymphocyte decreased, heterophils and monocytes increased. The eosinophils and basophils showed variation in their number.
The study showed efficacy of Monensin, Salinomycin and Clopidol in descending order respectively. Monensin was to be drug of choice against coccidiosis.
Availability: Items available for loan: UVAS Library [Call number: 0428,T] (1).
27.
Comparative Efficacy Of Oxfendazole, Albendazole And Ivermectin Against Gastro Intestinal Nematodes Of Horses
by Nadeem Kamal | Prof.Dr.Muhammad Ashraf | Dr. Mubasher | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1995Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0437,T] (1).
28.
Efficacy Of Various Ionophorous Antibiotics Against Coccidiosis In Quails
by Riaz Ahmad Khan | Dr. Khalid Pervez | Dr. Haji Ahmad | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1994Dissertation note: Two hundred and fifty, day old quail chicks were pruchased from a local hatchery and reared up to three weeks of age under hygienic conditions. After three weeks of age, quails were divided randomly into five groups. Group A was kept as control, group B as infected non treated, group C as monensin treated, group D as salinomycin treated and group E as suiphaquinoxalim treated.
After three weeks of age, groups B, C, D, and E were infected orally with mixed infection of avian Eimeria species, while group A was kept as control. Signs and symptoms of coccidiosis apperared after six days of infection. After apperarance of signs and symptoms the birds of group C and D were treated with monensin and salinomycin and group E treated with sulphaquinoxaline.
The effect of medication on feed consumption, weight gain, feed conversion ratio, mortality, oocyst count and dressing percentage were recorded weekly upto 6 weeks of age. There was significant difference (P<O.05) of feed intake between group B, C, D and E. Maximum feed intake was in group A, followed by group E, C, D, and B, respectively. Weight gain was maximum of group A followed by group E, C, D, and B respectively.
The feed conversion ratio (FCR) of control group A, was better than all other groups while feed conversion ratio of group B (infected nontreated) was poor than all other groups.
Oocysts count was zero on six days post of medication in group C, (monensin treated) while it was zero after eight days of treatment in group D (salinomycin treated) and oocyst count was zero after four days of medication in group E (suiphaquinoxaline treated). Oocyst count was 32.000 oocystlgm faeces in group B (infected nontreated) after 42 days of age. While it remained zero through out the experiment in control group (group A). Mortality was maximum (10%) in group B (infected non trearted) followed by in group D (4%) and group C, and group E (2%) respectively. While mortality remained zero in group A (control). Dressing percentage was better in group A (62.02%) followed by group E (59.2 1%), group C (58.45%) respectively.
Observing the effects of sulphaquinoxaline monensin and salinomycin on feed intake, weight gain, feed conversion ratio, mortality, oocysts count and dressing percentage in experimentally infected (coccidiosis) quails, it was concluded that sulphaquinoxaline has comparatively better results than monensin and salinomycin.
Availability: Items available for loan: UVAS Library [Call number: 0468,T] (1).
29.
Efficacy Of Various Chemotherapeutic Agents Against Experimentally Induced Avian Mycoplasmosis In Broiler Chicks
by Naveed Ahmad Khan Niazi | Dr. Muhammad Athar Khan | Dr. Asif | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1994Dissertation note: A total number of 200 day old broiler chicks were procured to determine the drug efficacy of tiamulin, tylosin and oxytetracycline against jylycoplasma gallisepticum infection in-vivo. The organism prior to its use was verified on the basis of morphology, staining reaction, cultural characteristics and biochemical tests. These birds were divided into 5 groups each having 40 birds. The birds of all groups were infected experimentally except group A birds. On the appearance of symptoms of CRD, group C, D and E were treated with tiamulin, tylosin and oxytetracycline respectively at the recommended doses of manufacturers for three consecutive days. The birds of group B were kept as untreated control. The efficacy of each drug was based upon morbidity percentage, mortality percentage, case fatality, clinical symptoms, feed-intake and necropsy lesions on postmortem. The tiamulin proved superior over other two drugs as only one bird died unlike tylosin-treated group D which recorded 2.5% mortality.
The oxytetracycline treated group E showed 7.5% mortality with the death of 2 birds. A total of 29 birds revealed no pathological lesion at necropsy in contrast to group E birds showing only 27 birds without necropsy lesions of CRD. The feed-intake was poorest in group E and was remained normal in both group C and D. After 144 hours post medication, the clearance of lesions were 96.6%, 90% and 76.6% for group C, D and E respectively.
Availability: Items available for loan: UVAS Library [Call number: 0469,T] (1).
30.
Effect Of Fascioliasis On The Blood Picture And Comparative Efficacy Of Different Fasciolicidal Drugs In Sheep
by Shazia Maqbool | Dr. Khalid Pervaiz | Dr. Mubasher | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1995Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0471,T] (1).
31.
A Study Of Changes In Blood Electrolytes And Pcv In Equine Colic
by Mazhar Ayaz, M | Dr. Khalid Pervaz | Dr. Muhammad Sarwar Khan | Dr. Shakil | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1995Dissertation note: Besides mechanized transportation horses have still global importance not only for the communication but it is thought as symbol of superiority in many countries of the world. Horses are confronted with colic once in their life span that some times results in uncompareable loss to the owner. Only a timely and accurate diagnosis is the beacon of hope to save the life. To study the effects of colic on PCV and Blood Electrolytes, twenty horses suffering from colic were taken into investigation to asses the site and type of colic, while ten normal horses were kept as control. Diseased horses were divided into three groups A, B & C mild, moderate and severe respectively. Physical signs of group A were of mild nature comprising swishing of the tail, looking at the flank and lying down for the short periods, while group B showed moderate pain like lying down but not violently and increased bouts of pain. Animals in group C exhibited signs of severe pain by showing severe depression, restlessness, patchy sweating, struggling violently and kicking at the belly due to sharp continuous pain. The heart rate, respiration and rectal temperature in all groups was increased. Rectal palpation was performed in all groups to determine the site of the disease. Changes found in blood electrolytes like Na+, K+, C1- and HCO3 were measured by flame photometry. Group A, B and C showed decrease in Na+, and HCO3 concentration in serum while concentration of K and C1 in serum were normal in all groups. PCV was measured by Wintrobe micro-haematocrit method in all groups. Group A and C showed normal PCV but it was lower in group B. These all observations showed that the animals of group A were suffering from impaction of ileacaecal valve. Pain was not so severe nature that may cause death in colic cases while the animals in group B were showing signs of spasmodic colic. The abnormalities were not so severe to threat the life of the animal but were elevated than the normal. Group C was considerably serious that might lead to death if unattended because the variations and findings were similar with obstruction of small intestine. The serum electrolytes in this group were increased than the other two groups alongwith the elevated respiration, heart rate and rectal temperature that were helping in assessing the condition of the animal. PCV was the reliable tool to know the degree of dehydration in the severe cases. Rectal palpation helped in differentiating the various segments of the intestines involved and the severity of the disease in the diseased animals.
Availability: Items available for loan: UVAS Library [Call number: 0472,T] (1).
32.
Prevalence Of Camel Tuberculosis By Using Short Thermal Test & Identificatiuon Of Organism From Lymph
by Laeeque, Sh. M | Dr. Muhammad Athar Khan | Dr. M. Sarwar Khan | Dr. Muhammd | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1994Dissertation note: In the present study an attempt was made to measure the prevalence of tuberculosis in camels by applying tuberculin test and post mortem examination of reactors and non reactors. Gross and microbiological examination of various lymph nodes of reactors and non-reactors was conducted.
Animals were physically normal, thin and emaciated and of different age groups. Short thermal test was employed as diagnostic test. The readings were taken at 8 hour post inoculation of tuberculin, and heat concentrated sysnthetic medium tuberculin (HCSM) was used at dose of 4m1 S/c. No adverse reaction of HCSM was noted during research.
Eleven animals gave positive reaction while no false positive and false negative case was recorded. Similarly no case of milliary T.B. could be noted among experimental animals.
Majority of the diseased animals were detected from a group of emaciated and aged animals. Whereas a small number from a group of thin animals was also affected. However, a group physically normal camels was found free from T.B.
Positive reactors showed higher pulse and respiration rate compared with negative reactors, post 8 hour inoculation.
Positive reactors were found to be a model set to observe the pattern of temperature rise during STT.
2 out of 3 positive reactors, showed macroscopic lesionsin mediastinal, lymph nodes. Out, of these 1 showed characteristic lesions of T.B. 1 showed only pin head point lesions in early stages. While other 1 showed only Mycobacterium tuberculosis on bacteriological examination and proved no visible lesions (NVL).
It was found that distribution of lesions were high among those animals which showed temperature difference (4oF between first and final reading.
This is notworthy that lung lymph nodes involvement was higher as compared to the lymph nodes from abdominal cavity, no lesion or acid fast bacilli (AFB) detected from supramammary lymph nodes of experimental animals
Overall 3 of the animals tested showed prevalence of tuberculosis
Availability: Items available for loan: UVAS Library [Call number: 0473,T] (1).
33.
Helminthiasis: Its Dissemination And Treatment With Fenbendazole In The Migrating Sparrows
by Ali Razmaara, Syed | Dr. Muhammad Athar Khan | Dr. Haji Ahmad | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Nature of contents: ; Literary form: Publisher: 1995Dissertation note: The present study was conducted to bust upon the worm load in the naturally parasitized migratory sparrows, and also to determine the effect of worm load on the blood picture. Furthemore the effect of broad spectrum anthelmintic like Panacur (fenbendazole) in the experimental group in terms of eggs per gm. of faeces pre and post medication.
For this experiment 400 live migratory sparrows were purchased randomly, out of which 200 birds were slaughtered and an incidence of 64.5% parasitic fauna was found. Sparrows were found infected, with two species of nematode i.e. Ascaridia gaul was 39.5% and Heterakis gallinarum was 25% respectively. None of the bird was found infected with trematode and cestode.
The hematology of the above 64.5% parasitized sparrows was performed. The study revealed that due to nematode infection there was a slight increase in Total leucocytic count and Heterophils whereas the Total erythrocytic count, Haernoglobin level, Lymphocytes and Eosinophils were decreased which may lead to anemia, loss of growth and production.
From the left 200 wild naturally parasitized sparrows, 86 (43%) birds were found positive. These sparrows were divided into two groups one was left as control and the other group was subjected to drug efficacy. Panacur (fenbendazole) at the rate of 9.9 mg/kg body weight which was given orally. The results were observed in terms of eggs per gm. of faeces pre and post medication after 24, 48 and 96 hours respectively. The control group showed progressive increase in ova count i.e. 12.82%, 24.79% and 48.72% respectively, whereas reduction in the ova count of the medicated group was gradually observed as 83.72%, 92.25% and 95.35%.
The poultry breeders and scientists are urged to make an effort how the wild birds could mechanically transmit the parasites from one region to another. An attempt should also be made for the better understanding of bacterial and viral infections dissemination.
Availability: Items available for loan: UVAS Library [Call number: 0474,T] (1).
34.
Comparative Evaluation Of Tension Band Wire And Steel Suture For Repair Of Transversepatellar Fracture In The Dog
by Sarfaraz Ahmad, M | Dr. Muhammad Arif Khan | Dr. Mazhar Iqbal | Dr. Mubashar | Faculty of Veterinary Sciences.
Material type: ; Format:
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; Literary form:
not fiction
Publisher: 1994Dissertation note: The fracture of patella usually falls in a special type of fracture, which is not treated by ordinary limb and bone fixation devices. Hence emphasis is given to counteract the distracting forces and to convert them into compressive forces to achieve the desired effects. Different types of internal fixation devices have been tried in the past for the repair of avulsion fractures like Tension Band wire, compression screws, compression plates, an steel sutures.
This study was conducted on 20 mongrel dogs divided into two groups of 10 animals each. These groups were designated as group A and group B. Two methods, Tension Band wire and square steel suture were used for the repair of transverse patellar fracture in dogs.
In group A, the right patella was surgically exposed, fractured and repaired by Tension Band wire with Thomas Splint on the same limb when the operated dog started bearing weight on its operated leg, the left patella was exposed and repaired using same technique but without Thomas Splint.
In group B the right patella was repaired by square steel suture with Thomas Splint. After six weeks, the left patella was operated and repaired using same technique but without Thomas Splint. The dog of each group was kept for a period of 16 weeks after surgery. The results were obtained on the basis of their clinical and radiographic picture.
The results of this study indicate that the use of steel suture is a better fixation device for the repair of transverse patellar fracture.
Availability: Items available for loan: UVAS Library [Call number: 0475,T] (1).
35.
A Comparative Study Of Different Anaesthetic Combinations In Equine
by Sajid Ijaz | Dr. Muhammad Arif Khan | Dr. Mubasher | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
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; Literary form:
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Publisher: 1995Dissertation note: These days the scope of anaesthesia is consistently increasing due to increase in surgical patients in veterinary practice. This change in trend is due to the awareness of the owners to different surgical problems and their solutions. They do not hesitate to get their animals treated with modern equipments and highly expensive medicine. To meet this challenge and demand of the owners, veterinary surgeons are taking keen interest to get the advanced knowledge and latest information of modern equipments and their usage in veterinary practice.
In the past surgery was performed by making temporary insensibility by asphyxiation, cerebral concussion by striking wooden bowl placed over the head with a hammer and a regional anaesthesia was attained by compression of nerves and blood vessels of the region to he operated upon. But these days different sedative and anaesthetic agents are being used to make the animal desensitize from all external stimuli. These drugs are available in volatile, nonvolatile and gaseous forms. The usage of anaesthetic agent entirely depends upon the species, age, weight, temperament of the patient, nature of the operation to he performed, cost and availability of the drug.
In this project three different combinations were tried in thirty animals of equine species to find out the best selection for major surgical interventions. The animals were divided into three groups often animal each. These groups were designated as Group A, B and C. Group A was anaesthetized with XylazineiPentothal sodium, Group B with Acepromazine/Pentothal sodium and Group C with Diazepam/Pentothal sodium. The efficacy of these combinations was measured on the basis of nature of induction, recumbency period, nature of recovery, different body reflexes, recording temperature, pulse, respiration, and statistical analysis of results.
The analysis of the results collected during this study clearly indicated that a combination of cliazepam with pentothal sodium was a better selection for anaesthetizing equine patients. This study aslo proved that combination comprising of xylazine and pentothal sodium could he used for minor surgical interventions as it produced light surgical anaesthesia.
It was concluded that a combination consisting of diazepam and pentothal sodium should be used for all types of major surgical procedures in equine practice.
Availability: Items available for loan: UVAS Library [Call number: 0476,T] (1).
36.
Antimicrobial Efficacy Of Different Drugs Against Experimentally Induced Salmonella Pullorum Infection In Broilers
by Ashfaq Ahmad Mirza | Dr. Muhammad Sarwar Khan | Dr. Mazhar Iqbal | Dr. Shakil | Faculty of Veterinary Sciences.
Material type: ; Format:
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; Literary form:
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Publisher: 1996Dissertation note: A total of 120 broiler chicks were randomly selected and divided into six groups viz A, B, C, D, E and F, consisting of 20 birds each. At 4 week of age, A to E groups were experimentally infected with Salmonella pullorum inoculum. Group E (infected, non-medicated) and F (non-infected and non-medicated) were kept as control. The groups A, B, C and D were treated with Ampicillin 20%, Oxy-N-50, Chioricol10 and Trimodin forte, respectively, post infection. All the groups were kept under close observation to record signs and symptoms of disease, mortality, body weight gain and Feed Conversion Ratio. Gross lesions in visceral organs were also noted during this study. Some blood parameters (TEC, TLC and Hb content) were also estimated, pre and post infection. A mortality percentage in groups A, B, C and D were recorded as, 25%, 35%, 15% and 10%, respectively, while 70% mortality was recorded in control group F. According to this trial Trimodin forte (Trimethoprim Plus Sulphadiazine) . afforded maximum protection against infection and proved best in relation to weight gain and F.C.R. Chloricol-10 (Chioramphenicol) stood second in the list, while Ampicillin-20% (Ampicillin Trihydrate) was the third drug in furnishing protection against the infection. Whereas, Oxy-N-50 (Oxytetracycline plus neomycin sulphate) was the least effective drug in respect of protection against pullorum disease. The signs of ill health appeared 3 to 4 days post infection were listlessness, ruffled feathers, droopy wings, loss of appetite, poor growth, depression, increased thirst and severe diarrhoea of chalky white colour. The postmortem findings were enlarged and congested liver streaked with haemorrhages, 2-3 times enlarged spleen (spleenomegaly), enlarged heart and pericarditis, congested and distended kidneys, area of gray hepatization in lungs, thickened and inflammed intestinal walls and presence of necrotic foci in cardiac muscles, liver, spleen, lungs, caeca, large intestine and muscles of gizzard. The Total Erythrocytic count and Haemoglobin contents were decreased and Total Leukocytic Count, were increased 3 days post infection. The findings of the present study will further elucidate the disease and help in diagnosis and treatment of this malady on large scale.
Availability: Items available for loan: UVAS Library [Call number: 0482,T] (1).
37.
A Serological And Coprological Study Of Paramphistomiasis In Buffalo
by Jameel Ahmad | Dr. Khalid Pervaiz | Dr. Haji Ahmed | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
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; Literary form:
not fiction
Publisher: 1997Dissertation note: Two hundred faecal samples, serum samples and paramphistomes used in the present study collected from main slaughter house of Lahore and from surrounding of the city.
Faecal examinations were carried out with fresh smear technique and 61.5% animals found positive for paramphistomiasis. Serum was separated from the blood samples collected from infected and suspected buffaloes for the performance of enzyme-linked immunosorbent assay. Paramphistome crude antigen was prepared from fresh stomach flukes, which contained 95.66 mg proteins/mi at 545 nm.
For performing the enzyme linked immunosorbent assay, the 96 well ELISA plates were coated with crude antigen & kept overnight & then the other procedure for the assay was followed, & the serum samples were tested with paramphistome crude antigen. In positive samples, the yellowish-brown colouration was formed.
In faecal examination, 61.5% and in the ELISA 100% of the animal found positive.
From the conclusion of the results if was found that ELISA (100%) has given more positive results then faecal examination (61.5%).
Availability: Items available for loan: UVAS Library [Call number: 0490,T] (1).
38.
Comparative Efficacy On Newly Introduced Antibacterial Drugs Against Experimentally Induced Escherichia Coli
by Zubair, M | Dr. Khalid Pervaiz | Dr. Mubasher | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1996Dissertation note: Pakistan faces an acute shortage of animal protein which is acknowledged as a serious problem at national level. Since broilers are the fastest converters of crude protein into digestible high quality protein for human consumption. There is much need in the production of broilers for the said reason in Pakistan. The upgrading of poultry industry is suffered from huge losses caused by certain diseases of bacterial origin. Amongst bacterial diseases, Escherichia coli is the worst threat to poultry industry. Therefore, concrete and consistent effort was done in this project to control the Eschericia coli infection.
The present project was done to study the efficacy of different drugs on prevalent strains of E. coli isolated from broilers that were collected from Diagnostic Laboratory, office of the Project Director, Poultry Production, 16-Cooper Road, Lahore and various Farms in the vicinity of Lahore.
Six different antibacterial drugs which comprised of avitryl, advocin, plasmacolin, flumequine gentamicin and inoxyl were used to check the sensitivity of the isolates. In-vitro the sensitivity results was in this order avitryl, advocin, plasmacolin, gentamicin, flumeuine and inoxyl respectively. Avitryl emerged as best drug.
The pathogenicity of the isolated strains was tested in albino mice taken from V.R.I., Lahore. The confirmed pathogenic isolates of . coli were diluted upto 3x108 bacteria per 0.25 ml, this dilution ws made after doing total viable count and the dose was injected intra-peritoneally to five albino mice while 5 albino mice were kept as controls.
These six drugs were further tested for their efficiency in broilers against . coli infection. A total of two hundred and forty birds reared upto four weeks of age and then they were divided into eight groups, A, B, C, D, E, F, G and H, each having 30 birds. Group H was kept as non-infected and non- treated. While Group G was infected but not treated. The remaining groups A, B, C, D, E and F, 16 hours after infection were treated with avitryl, advocin, plasmacolin, flumequine, gentamicin and inoxyl for five days respectively. All the groups were kept under close observation and their mortality and feed efficiency was noted.
In group G maximum mortality was noted i.e. 57.14 while in the group A, B, C, D, E and F, the mortality recorded was 22.72, 30, 33.33, 40.90, 47.82 and 52.17 respectively.
Avitryl was proved to be the highest protection against coli infection and best in relation to F.C.R. by this experiment.
Availability: Items available for loan: UVAS Library [Call number: 0492,T] (1).
39.
Comparative Evaluation Of Different Suture Materials With And Without The Usage Of Thomas Splint For The Repair Of Transversely Cut Tendo Achilles In The Dog
by Hassan Saqlain | Muhammad Arif Khan | Dr. Muhammad Younas | Dr. Shakil | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1997Dissertation note: Tendons are an important link In the locomotive system, the main physiological function of which is to transmit forces that produce characteristic mechanical responses. The tendon function is extremely important in movement. Injuries and disturbances in tendon are common, thus creating extreme difficulties in locomotion. The repair of tendons had always been an enigma in the past. However with the advancement of surgery, the repair of tendon has become possible and the patient return to a normal functioning life.
The present study was launched on twelve mongrel dogs. The achilles tendon was cut surgically and then repaired with two different suture materials i.e. stainless steel and Nylon (No.1). Three groups were made i.e. group A, B and C. Group A for repair of the achilles tendon with stainless steel wire (gauge 24) alongwith a comparison of repair with and without a thomas splint. The group 'B' was repmred with Nylon suture material (No.1) as well as with the comparison of thomas splint application
The group C served as a control group in which no suture material was used, however the effect of thomas splint was compared with and without its application. Of the twelve animals, four were put into each group.
In every group, first the achilles tendon of the right hindlimb was repaired with and without thomas splint. After eight weeks healing, the tendo-achilles of the left hind limb was repaired with the same suture material with and without thomas splint. The wounds were smeared with furacin ointment. Antibiotics were administered 24 hours prior to surgery and continued for 5 days post-surgically. All the dogs were kept under observation for eight weeks postsurgically. however, the total project took 16 weeks. The tendons were tested for repair (healing) by examination, lameness tests, posteuthanasia finding and histopathological studies.
The success rate of the tendons repaired with stainless steel sutures (guage 24) was 50% and with Nylon suture material (No. 1) 100%. The results clearly Indicated that the application of Nylon.
Availability: Items available for loan: UVAS Library [Call number: 0516,T] (1).
40.
Comparison Of Perfused And Non Perfused Jejunal Auto Transplants For Reconstruction Of Massive Abdominal
by Ghalia Qayyum | Dr. Mazhar Iqbal | Dr. muhammad Younas | Dr. Shakil | Faculty of Veterinary Sciences.
Material type: ; Format:
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; Literary form:
not fiction
Publisher: 1997Dissertation note: Surgeons occasionally see patients who have malignant soft tissue tumors, loss of a part due to trauma or excessive debridement of the abdominal wall. Regardless of the etiology they represent challenging anatomical problems, both with respect to resection and especially to reconstruction. Many defects are unsightly and difficult to appose by the surrounding tissue. SuIeons in medical field as well as veterinarians have tried and reported many surgical corrections to these conditions.
Twenty clinically healthy mongrel dogs of either sex were used for the experimental translocation of jejurial auto-grafts for the resurfacing of massive abdominal wall defects. The dogs were randomly divided into two groups of 10 animals each. Laparotomy was carried out by a vertical incision in right lateral recumbency. A portion of jejunum 12 cm long was selected and isolated from rest of the intestinal tract with its mesenteric blood supply intact. The continuity of the small bowel was restored by end-to-end anastomosis.
The isolated segment of jejunum was then processed and cut open longitudinally along the antimesenteric border. After wards the open patch was cut into two equal pieces, perpendicular to the long axis and then sutured together parallel, so as to have even bigger surface area of the graft to cover a defect which was wider in width and could be repaired by single width of the intestine. In group I, both the parts of intestine sutured together retained their blood supply intact. In group II, one half of the transplant was rendered avascular. Using the previous incision site, a full thickness 6x6 cm, square shape defect was created in the abdominal wall. The jejunal patch was placed over the defect in the abdominal wall, with its mucosal surface apposing the external fascia. Simple interrupted sutures using chrornic cat gut No.2 were used to tailor the patch in such a way that normal contours of abdominal wall were reconstituted. A drain was placed at the site of operation and the subcutaneous tissue and skin were closed in a routine manner.
In group-I there was no mortality and no herniation of the bowel occurred through the operative site. The graft was well tolerated by the animals as it was homologous. In group-TI the nonvascularised portion of the graft did not develop its new blood supply leading to its death and sloughing. Eventration took place on 6th day and the animals died, except one dog. It was concluded on the basis of this study that:
1. In group-I perfused pedicle grafts provided 100% resurfacing to the abdominal wall defects.
2. The mucosa of the bowel transplant under went degeneration.
3. The junctional histology of the graft revealed a thick layer of fibrous tissue indicating perfect union between the two portions of the graft.
4. A marked inflammatory reaction was also evident.
5. There was clear cut histological evidence of failure with loss of cellular integrity and no production of collagen fibers in the non perfused group.
In a nut shell the chosen method of reconstruction was consistent with the hierarchy of treatment priorities, which makes survival paramount, followed by function, freedom from pain and acceptable appearances. Thus when there is no other way of saving the animals life other than surgical intervention, the satisfaction derived from such a successful, last resort operation is indeed a valuable encouragement to a young veterinary surgeon.
Availability: Items available for loan: UVAS Library [Call number: 0527,T] (1).
41.
Prevalence Of Puff Disease In Horses With Biochemical And Chemotherapeutic Studies
by Shamoon ur Rashid | Dr. Muhammad Sarwar Khan | Dr. Javed | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1997Dissertation note: This project was designed to find out the prevalence of puff disease in horses in Lahore area. This study also included chemotherapeutic effect of two different treatments and biochemical studies.
This study was conducted during the month of July-September, 1996 at Outdoor Hospital, College of Veterinary Sciences, Lahore and around the city of Lahore. For the prevalence of puff disease 290 horses were examined and their clinical signs were observed. Investigation showed that the occurrence of puff disease in horses was 12.14% i.e. 36 horses out of 290 were found positive.
Thirty positive cases were treated with two different groups of treatments. With 1st group of treatment 5 horses were cured completely and with 2nd group of treatment 11 horses were cured completely. The results of treatment were based on the reversal of clinical signs. Serum samples of positive horses were also observed before and after treatment for the detection of glucose, cholesterol and chloride levels.
Availability: Items available for loan: UVAS Library [Call number: 0536,T] (1).
42.
A Clinico Epidemiiological Study Of Bacterial And Parasitic Causes Of Respiratory Syndrome In Sheep And Goats
by Waseem Shahzad | Dr. Khalid Pervaiz | Dr. Khushi | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1997Dissertation note: In Pakistan sheep and goats production is playing a very important role in bridging the protein gap among our population. Sheep and goats not only provide us high quality meat for our consumption but also wool fibre and high quality leather. In Pakistan every year there is lot of mortality due to respiratory tract infections in sheep and goats especially due to pneumonia which results from a variety of causes' namely, bacterial, viral, parasitic, mycoplasmal and fungal etc. It causes high economic losses due to increased rate of mortality. This study was carried out on two hundred sheep and goats of either sex including all age groups brought to out door hospital of College of Veterinary Sciences, Lahore during February 1997 to June 1997. In the present study isolation and identification of bacterial and parasitic etiological agents of the respiratory tract problems in sheep and goats was carried out. According to this study many bacterial agents causes respiratory problems in sheep and goats, out of 132 positive nasal samples Pasteurella multocida was isolated from 32 (24%), . haemolytica 43 (33%), Corynebacterium 26 (20%), 23 (17%), Streptococcus 18 (14%) and Escherichia ççjj 20 (15%) from affected sheep and goats. Similarly many lungworms cause respiratory problems, out of 82 positive faecal samples Dictvocaulus filaria was isolated from 76 (92.6%) and Protostrongvlus rufesence 6 (7.3%) from affected sheep and goats. The haematological study of the infected and non infected animal showed that there were decreased values of total erythrocytic count, packed cell volume and differential leucocytic count and increased values of total leucocytic count and erythrocytic sedimentation rate of affected animals.
Availability: Items available for loan: UVAS Library [Call number: 0539,T] (1).
43.
A Clinicopathological Study Of Lactic Acidosis In Sheep And Goats
by Usman, M | Dr. Khalid Pervez | Dr. Javed | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1998Dissertation note: A total of 100 sheep and goats suffering from lactic acidosis brought to Outdoor hospital, College of Veterinary Sciences, Lahore were selected as experimental animals while the same number was kept as control to access the events of lactic acidosis. The temperature, pulse rate, respiration rate, rumen and serum p11, serum bicarbonate, packed cell volume, ruminal movements and ruminal protozoa of the two groups were studied.
It was found that rectal temperature, blood pH, rumen p11, serum bicarbonate and ruminal movements decreased significantly in acidotic group as compared to control group. Simultaneously the pulse rate, respiration rate and packed cell volume increased, significantly in lactic acidotic group as compared to control group. Mean values observed in goat were serum pH 7.075±0.11 rumen p11, 4±0.57 serum bicarbonate, 12.42±0.59 mEq/liter, packed cell volume 67.50±3.2%, temperature 100.9±0.19°F, pulse rate 168.6±3.77 per minute and respiration rate 17.00±0.82 and in sheep mean values were 7.025±0.85, 4±0.57, 12.42±0.66 rnEq/liter, 64.25±0.21%, 100.9±0.82 °F, 168.6±3.77 per minute and 17.00±0.82 per minute respectively.
The rumen protozoa was found to be completely destroyed in the experimental group. There was complete ruminal stasis in lactic acidotic group.
Availability: Items available for loan: UVAS Library [Call number: 0550,T] (1).
44.
Retrospective Epidemiological Study And Clinico Serological Observations On Haemorrhagic Septicaemia In Cattle And Buffaloes In District Dera Ghazi Khan During 1996
by Zaka Saeed | Dr. M. Athar Khan | Dr. M. Naeem | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
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; Literary form:
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Publisher: 1998Dissertation note: An active surveillance was conducted to understand the incidence and economic losses due to Haemorrhagic septicaemia in randomly selected 10 villages of tehsil/district Dera Ghazi Khan. The informations about the morbidity, mortality and case fatality rates
related to HS were collected on a prescribed questionnaire during the previous year.
The data of 4248 animals from the affected villages was cllected which included 2963 buffaloes (1042 young and 1921 adult) and 1285 cattle (417 young and 868 adults). The morbidity, mortality and case fatality rates were 22.3%, 19.64% and 88.04% in buffaloes (with 57.58%, 52.30% and 90.83% in young and 3.17%, 1.92% and 60.65% in adult animals) and 6.07%, 3.19% and 52.56% in cattle (with 8.63%, 5.27% and 61.11% in young and 4.83%, 2.18% and 45.23% in adult animals) respectively.
The clinical signs observed were body temperature 104-107°F (17.39%), respiratory distress (14.61%), salivation (14.54%), nasal discharge (9.67%) and edema around throat (9.34%).
The average total serum protein, serum albumin and serum globulin of diseased buffalo were 4.99g/dl, 2.60g/dl and 2.42g/dl while in diseased cattle the values were 5.78g/dl, 2.47g/dl and 2.35g/dl.
Indirect haemagglutination test (IHA) used for the antibody detection against H.S. revealed that the GMT of diseased buffaloes and cattle was lower than that of healthy animals. No carrier buffalo and cattle could be detected by nasopharyngeal swabs.
Economic losses due to haemorrhagic septicaemia have been estimated to be Rs. 2.615 million per annum.
Availability: Items available for loan: UVAS Library [Call number: 0560,T] (1).
45.
Epidemiology And Economic Losses Of Trichostrongylid Parasites In Sheep
by Sarwar Khan, M | Dr. Muhammad Athar Khan | Dr. Haji Ahmad | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1997Dissertation note: The meteorological data recorded during the study period from 1.1.96 to 31.12.96 showed the maximum temperature in June as
36.5°C and minimum temperature in December as 6.8°C. Maximum and minimum Humidity was recorded in the month of September and April as 85% and 55% respectively. The maximum rainfall during the year was recorded in the month of August as 660 mm.
The faecal egg counts of sheep grazing on permanent pasture showed the minimum EPG during first week of January while maximum EPG on nid of September and first week of October.
Pasture larval counts were performed on permanent pasture and experimental plot for the recovery of trichostrongylid larvae. The maximum number of larvae was recovered on 16th September, 1996, while minimum number was recovered in January and February from permanent pasture and experimental plot respectively. Two species of trichostrongylids were identified i.e. Haemonchus contortus and Trichostrongvlus colubriformis.
The faecal and larval counts were very low in the months of January and February, the counts started rising in March. Peak counts were seen in the month of September. Decline in counts started in late October and reached to minimum in December.
Mature and immature worm counts of slaughtered sheep were performed at 15 days interval. The, overall prevalence oftrichostrongylid parasites was 34%. The maximum number of mature parasites were seen during first week of October which was886 whereas maximum number of immature parasites including hypobiotic was 326 on 1st of December. During this study the average fecundity/female of contortus and L colubriformis parasites were calculated as 721 and 209 respectively. A spring rise in worm egg counts was experienced in mid of March. A pen parturient rise in the worm egg counts of pregnant and lactating ewes indicated the maximum counts during lambing week.
An experimental group of sheep with mixed infection of trichostrongylid parasites showed the similar pattern of EPG counts as of naturally infected sheep.
A study was performed to evaluate any protection provided by a particular Flaemoglobin type to trichostrongylid infection hut not difference could be observed. The Asparate Aminotransferase (AST) and total protein levels of infected sheep were decreased as a result of increase in the intensity of infection.
A decrease in R.B.C. counts, Haemoglobin, Packed cell volume and lymphocyte counts was observed both in experimentally and naturally infected slaughtered sheep. However, an increase in total leukocytic count (TLC) alongwith an increase in the ratio of neutrophils, eosinophils and basophils was observed.
At the end of experiment infected sheep gained 5.71 Kg/head less body weight and produced 4 3 grn less wool as compared with non-infected group. Based on epidemiological information the suggestions for control of the, trichostrongylid infection are submitted alongwi th recommendations for further studies.
Availability: Items available for loan: UVAS Library [Call number: 0595,T] (1).
46.
Evaluation Of Liver Functions At Varying Degrees Of Hepatectomy In Dogs
by Farhan Ahmad Atif | Dr. M. Arif Khan | Dr. Asim Aslam | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1999Dissertation note: Liver is the most important organ because of its multiplicity of functions. It played a pivotal rote in the nutrition and maintenance of the body.
In this project 16 dogs were taken and divided into 4 groups comprising 4 dogs each. In group-A total removal of right lateral lobe was performed. In group-B half part of the right lobe was resected. Group-C was sham operated in which only laparotomy was experienced. Whereas, group-D acted as control.
Liver function tests were conducted in all the groups before and after surgery. rfhe.e was slight elevation in the values of liver enzymes which remained within the normal range except alkaline phosphatase.
Metabolic ability was not affected appreciably after resection of half and complete removal of right lateral lobe.
All the dogs were euthanized after 8 weeks post-operatively. The dogs of group-B showed hepatic regeneration that was 31.2, 38.8 and 28.3 percent in dog No.6, 7 and 8 respectively. The histopathology of regenerated tissue revealed normal hepatic tissue.
The analysis of results has clearly indicated that resection of liver upto this extent does not alter liver functions noticeably and thus partial hepatectomy can be performed without any fear.
Availability: Items available for loan: UVAS Library [Call number: 0596,T] (1).
47.
Comparative Efficacy Of Various Drugs Used Against Naturally Infected Horsed With Babesiosis
by Mamoona Ali | Dr. Khalid Pervez | Dr. Asif | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1999Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0600,T] (1).
48.
Prevalence Of Canine Babesiosis In District Lahore & Comparative Efficacy Of Different Drugs Against Naturally Infected Dogs With Babesiosis
by Haroon Ahmad | Dr.Khalid Pervaiz | Dr. Muhammad Ashraf | Dr.S.A.Jafri | Faculty of Veterinary Sciences.
Material type: ; Format:
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; Literary form:
not fiction
Publisher: 2000Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0655,T] (1).
49.
Anthelmintic Efficacy Of Moxidectin, Ivermectin And Levamisole Against Toxocara Vitulorum In Buffalo Calves
by Rahmatullah | Prof.Dr.Muhammad Ashraf | Dr. Muhammad Athar Khan | Dr.Kamran | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2000Dissertation note: hits study was conducted to evaluate the anthelmintic efficacy of newly introduced drug moxideclin against Toxocara vitulorun, in buffalo calves under held conditions and to compare its efficacy and treatment cost with other anthelmintics (ivermectin atid levamisole) being used.
In this project total of 80 buffalo calves Positive for Toxocara i'itulorum. based on faecal examination, were selected from (he field, and divided randomly into four equal groups i.e. A, 13, C and 1) containing 20 animals in each. Calves of group 'A' were treated with moxidectin, group 'B' were treated with ivermectin. group 'C' were treated with levamisole and group '1)' were kept as untreated control.
Faecal samples were collected from each calf at clay zero (premedication), day 7th, day I 5th, and day 21st postmedicalion. Ffhicacy of each drug was calculated on the basis of reduction in eggs per gram of faeces.
Anthelmintic efficacy of moxidectin at (lie (lose level of 200ug / kg body weight was I 00%,efficacy of ivermectin at the close level of 200ug/kg body weight was 99.55%, and the efficacy of levamisole at the close level of 7.5mg/kg body weight was 99.035%, 21 st days post medication.
From this study it was concluded that moxiclectin and ivermectin has excellent effect against Toxocara i'lluloriun but they are much expensive while levamisole has also excellent efficacy against T vituloruni and (his drug is more economical for the farmers.
Availability: Items available for loan: UVAS Library [Call number: 0658,T] (1).
50.
Magnitude Of Health Problems Of The Livestock Population, Serological Findings And Cost/Benefit Ratio At A Farmer Level
by Ajmal Shahid, M | Dr . Muhammad Athar Khan | Dr . Muhammad | Dr . Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1999Dissertation note: An active surveillance was conducted in 10% villages of canal irrigated, waterlogged, Idara-e-Kissan, river side and urban areas of tehsil Renalá Khurd district Okara through a questionnaire over a period of one year i.e. March, 1998 to February, 1999 to determine the magnitude of various livestock health problems.
In total buffalo population 7333 of all the strata morbidity, mortality case fatality was 57.73%, 10.07% and 17.45% while in 2635 cattle, these observation were 38.44%, 1.25% and 3.2% respectively due to various livestock problems. In 3445 goat, 1604 sheep population, the result were 27.95%, 8.06%, 28.86% and 30.17, 9.35%, 30.99% respectively. The highest incidence of haemorrhagic septicaemia 25.38% and 6.48% in young and adult buffalo population respectively was observed in river side area. Waterlogged area was next 24.38%1and 5.165% to river side while least incidence in urban area. Foot and mouth disease incidence was highest 19.28% and 22.01% respectively in young and adult buffalo along river side with no incidence in urban area. Highest. incidence of diarrhoea 11.11% in young buffalo population was observed in waterlogged area.
Similarly highest incidence of Mastitis observed was 3.07% in waterlogged area in adult cattle. The highest incidence 23.64% of FMD was observed in waterlogged areas.
Incidence of enterotoxemia in young sheep population were high 18.40% than young goat 12.35% while it was high in adult goat 10.23% than 8.99% in adult sheep.
Total economical losses due to various livestock disease was calculated R.8408067 (US$ 158642.77). The cost and benefit ratio at a farmer level was 1:2.03.
Antibodies were detected against haemorrhagic septi caem i a through IHA, in buffalo and cattle revealed that highest GMT in vaccinated buffalo and cattle was 55.69 each. These titers were also observed in affected and unvaccinated (might be as carrier) along with the recovered animals.
Availability: Items available for loan: UVAS Library [Call number: 0664,T] (1).
