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1. Prevalence Of Lymnaea Snails, In Lahore District, & Their Eradication By A Molluscicide Copper Sulphate

by Talib Hussain, Mughal | Dr. mhammad sarwar khan | Dr. Haji ahmad | Dr. Khalid parvez | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1993Dissertation note: The study was designed to know about the prevalence of the Lymnaea snails, identification of infected and non infected snails with intermediate stages of liver fluke and to recommend suitable copper sulphate dilution i.e. lmg/66 and lmg/lOO as molluscicide under laboratory and experimental pond conditions. One thousand snail/tern specimens were collected, 200 from each of four ponds and a natural habitat. The snails were collected fortnightly between October 1992 to March 1993. Prevalence of Lymnaea species was found to be 42.36% and infection of Lymnaea snails with intermediate stages of hepatica ranged between 37.50% and 68.75% in five habitats studied during the period from October 1992 to March 1993. copper sulphate dilution lmg/lO0 ml (10 PPM) was found to be effective as molluscicide and safe for other aquatic fauna and vegetation. Availability: Items available for loan: UVAS Library [Call number: 0346,T] (1).

2. Efficacy Of Triclabendazole Against Fascioliasis In Sheep And Goat Under The Field Conditions

by Haleem Hasan, Shah | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahmad | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1994Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0374,T] (1).

3. Comparative Efficacy Of Nitrofurans, Sulphadimidine & Monensin Against Coccidiosis In Sheep & Goats Under Field Conditions

by Anselm Lewis, Khokhar | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahmad | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1993Dissertation note: The present work was designed to study the comparative efficacy of Nitrosol, Suiphadimidine and Monensin against naturally infected sheep and goats with coccidiosis. Forty sheep and forty goats (infected) were selected and divided into four groups each i.e. S1, 2, S3, 84 and G, 02, G, 04 respectively. The animals of groups S and were treated with nitrosol 15 mg/kg body weight, S2 and 02 with sulphadimidine 140 mg/kg body weight, S3 and G with monensin 5 mg/kg body weight daily for five days. The sheep and goats in groups S4 and G4 were not medicated and served as control. The oocyst count per gram of faeces were compared on the 7th, 15th and 21st day of post medication. The oocyst count was reduced in groups S, S2, and S3 by 95.79%, 99.53% and 85.81% and in groups 1, G by 95.97%, 99.60% and 85.01%. The oocyst count in infected untreated control groups S4 and 04 increased. All the three anticoccidials tested gave appreciable response in reduction of oocyst counts but suiphadimidine was found to be the best amongst the three drugs. Nitrosol proved to be the 2nd whereas monensin proved to be the third in efficacy against coccidiosis in sheep and goats. No side affects of these drugs were observed) it is suggested that further research should be planned to test the efficacy of other anticoccidial drugs like lasalocid, amprolium colpidol, robenidine coxistac etc. under local conditions to select new drugs against coccidiosis in sheep and goats. Availability: Items available for loan: UVAS Library [Call number: 0376,T] (1).

4. Effect Of Routine Deworming On The Development Of Resistance Against Git Nematodes In Sheep

by Akram, M | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahmad | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1994Dissertation note: In this project the effect of routine deworming on GIT nematodes in sheep was studied with particular reference to the development of drug resistance. Comparison was studied by treating the flocks where routine deworming was practiced with the levamisole and albendazole and where routine deworming was not practiced with any medicine. One twenty sheep positive for GIT nematodes infection were selected. They were divided into six groups A, B, C, D, E and F comprising of 20 animal in each group. Animals of group A, B, C were selected from two different floclwhere routine deworming was practiced with levamisole and albendazole respectively. Animals of group D, E, & F were selected from unregistered private flocl where routine deworming was not practiced. Rectal faecal samples were collected before medication and at the seventh day of medication from all the six groups of sheep to count the eggs per gram of faeces and to count the number of larvae after culture under laboratory conditions. Groups A & D were treated with the levamisole orally at the dosage rate of 7.5 mg/kg. Groups B and E were medicated with albendazole orally at the dosage rate of 5 mg/kg and groups C & F were kept as control and remained untreated. Then the efficacy of levamisole and albendazole in addition to the development of resistance against these anthelmintics was estimated. Experimental study revealed that the levamisole showed 98.73% efficacy in the first timely dewormed flock and no any resistance was recorded whereas, 72.55% efficacy was noticed in the regularly dewormed flock, with a slight resistance. Albendazole had 97.13% efficacy in the first timely dewormed private flock and 61.24% efficacy in the regularly dewormed flock. This shows a strong evidence of resistance in the albendazole treated flock. No side effect were observed in both the groups. Levamisole was found better dewormer with less chances of resistance. However, both drugs can be used safely to achieve control of nematode parasites in sheep. Availability: Items available for loan: UVAS Library [Call number: 0421,T] (1).

5. Efficacy Of Various Ionophorous Antibiotics Against Coccidiosis In Quails

by Riaz Ahmad Khan | Dr. Khalid Pervez | Dr. Haji Ahmad | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1994Dissertation note: Two hundred and fifty, day old quail chicks were pruchased from a local hatchery and reared up to three weeks of age under hygienic conditions. After three weeks of age, quails were divided randomly into five groups. Group A was kept as control, group B as infected non treated, group C as monensin treated, group D as salinomycin treated and group E as suiphaquinoxalim treated. After three weeks of age, groups B, C, D, and E were infected orally with mixed infection of avian Eimeria species, while group A was kept as control. Signs and symptoms of coccidiosis apperared after six days of infection. After apperarance of signs and symptoms the birds of group C and D were treated with monensin and salinomycin and group E treated with sulphaquinoxaline. The effect of medication on feed consumption, weight gain, feed conversion ratio, mortality, oocyst count and dressing percentage were recorded weekly upto 6 weeks of age. There was significant difference (P<O.05) of feed intake between group B, C, D and E. Maximum feed intake was in group A, followed by group E, C, D, and B, respectively. Weight gain was maximum of group A followed by group E, C, D, and B respectively. The feed conversion ratio (FCR) of control group A, was better than all other groups while feed conversion ratio of group B (infected nontreated) was poor than all other groups. Oocysts count was zero on six days post of medication in group C, (monensin treated) while it was zero after eight days of treatment in group D (salinomycin treated) and oocyst count was zero after four days of medication in group E (suiphaquinoxaline treated). Oocyst count was 32.000 oocystlgm faeces in group B (infected nontreated) after 42 days of age. While it remained zero through out the experiment in control group (group A). Mortality was maximum (10%) in group B (infected non trearted) followed by in group D (4%) and group C, and group E (2%) respectively. While mortality remained zero in group A (control). Dressing percentage was better in group A (62.02%) followed by group E (59.2 1%), group C (58.45%) respectively. Observing the effects of sulphaquinoxaline monensin and salinomycin on feed intake, weight gain, feed conversion ratio, mortality, oocysts count and dressing percentage in experimentally infected (coccidiosis) quails, it was concluded that sulphaquinoxaline has comparatively better results than monensin and salinomycin. Availability: Items available for loan: UVAS Library [Call number: 0468,T] (1).

6. Helminthiasis: Its Dissemination And Treatment With Fenbendazole In The Migrating Sparrows

by Ali Razmaara, Syed | Dr. Muhammad Athar Khan | Dr. Haji Ahmad | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Nature of contents: biography; Literary form: Publisher: 1995Dissertation note: The present study was conducted to bust upon the worm load in the naturally parasitized migratory sparrows, and also to determine the effect of worm load on the blood picture. Furthemore the effect of broad spectrum anthelmintic like Panacur (fenbendazole) in the experimental group in terms of eggs per gm. of faeces pre and post medication. For this experiment 400 live migratory sparrows were purchased randomly, out of which 200 birds were slaughtered and an incidence of 64.5% parasitic fauna was found. Sparrows were found infected, with two species of nematode i.e. Ascaridia gaul was 39.5% and Heterakis gallinarum was 25% respectively. None of the bird was found infected with trematode and cestode. The hematology of the above 64.5% parasitized sparrows was performed. The study revealed that due to nematode infection there was a slight increase in Total leucocytic count and Heterophils whereas the Total erythrocytic count, Haernoglobin level, Lymphocytes and Eosinophils were decreased which may lead to anemia, loss of growth and production. From the left 200 wild naturally parasitized sparrows, 86 (43%) birds were found positive. These sparrows were divided into two groups one was left as control and the other group was subjected to drug efficacy. Panacur (fenbendazole) at the rate of 9.9 mg/kg body weight which was given orally. The results were observed in terms of eggs per gm. of faeces pre and post medication after 24, 48 and 96 hours respectively. The control group showed progressive increase in ova count i.e. 12.82%, 24.79% and 48.72% respectively, whereas reduction in the ova count of the medicated group was gradually observed as 83.72%, 92.25% and 95.35%. The poultry breeders and scientists are urged to make an effort how the wild birds could mechanically transmit the parasites from one region to another. An attempt should also be made for the better understanding of bacterial and viral infections dissemination. Availability: Items available for loan: UVAS Library [Call number: 0474,T] (1).

7. Comparative Efficacy Of Oxyclozanide, Rafoxanide And Bithionol Sulphoxide Against Paramphistomiasis In Buffaloes

by Umar, M | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahmad | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1998Dissertation note: The present project was designed to test the anthelmintic efficacy of oxyclozanide, Rafoxanide and Bithionol suiphoxide against paramph istomiasis in naturally infected buffaloes. The comparative anthelmintic trials were conducted among Nilzan drench - Id (Oxyclozanide 3.0% + Levamisole 1.5%,), Fasifree - Prix (Rafoxanide 30 mg/mI), Irchasol - Medivet (Bithionol sulphoxide 10% + Levamisole 1.5%) and Nilverm drench - ICI (Levamisole 1.5%) against paramphistomiasis in buffaloes. Seventy five naturally infected buffaloes were selected and divided into five equal groups i.e. A, B, C, D and E containing 15 animals each. Each animal of group A was given Nilzan drench (lml/2kg body weight), group B was given Fasifree (lml/4kg body weight), group C was given Irchasol (lml/2kg body weight), group D was given Nilverm (lml/2kg body weight), while group E was kept as control. The efficacy of anthelmintics was evaluated by counting eggs per gram (EPG) of faeces on day 7, 14 and 21 post-medication. The mean efficacyh of Nilzan drench was 97.29%, mean efficacy of Fasifree was 98.5% and of Irchasol was 85.56% while Nilverm did not have any effect for the treatment of Paramphistomiasis in buffaloes under field conditions. Availability: Items available for loan: UVAS Library [Call number: 0547,T] (1).

8. Epidemiology And Economic Losses Of Trichostrongylid Parasites In Sheep

by Sarwar Khan, M | Dr. Muhammad Athar Khan | Dr. Haji Ahmad | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1997Dissertation note: The meteorological data recorded during the study period from 1.1.96 to 31.12.96 showed the maximum temperature in June as 36.5°C and minimum temperature in December as 6.8°C. Maximum and minimum Humidity was recorded in the month of September and April as 85% and 55% respectively. The maximum rainfall during the year was recorded in the month of August as 660 mm. The faecal egg counts of sheep grazing on permanent pasture showed the minimum EPG during first week of January while maximum EPG on nid of September and first week of October. Pasture larval counts were performed on permanent pasture and experimental plot for the recovery of trichostrongylid larvae. The maximum number of larvae was recovered on 16th September, 1996, while minimum number was recovered in January and February from permanent pasture and experimental plot respectively. Two species of trichostrongylids were identified i.e. Haemonchus contortus and Trichostrongvlus colubriformis. The faecal and larval counts were very low in the months of January and February, the counts started rising in March. Peak counts were seen in the month of September. Decline in counts started in late October and reached to minimum in December. Mature and immature worm counts of slaughtered sheep were performed at 15 days interval. The, overall prevalence oftrichostrongylid parasites was 34%. The maximum number of mature parasites were seen during first week of October which was886 whereas maximum number of immature parasites including hypobiotic was 326 on 1st of December. During this study the average fecundity/female of contortus and L colubriformis parasites were calculated as 721 and 209 respectively. A spring rise in worm egg counts was experienced in mid of March. A pen parturient rise in the worm egg counts of pregnant and lactating ewes indicated the maximum counts during lambing week. An experimental group of sheep with mixed infection of trichostrongylid parasites showed the similar pattern of EPG counts as of naturally infected sheep. A study was performed to evaluate any protection provided by a particular Flaemoglobin type to trichostrongylid infection hut not difference could be observed. The Asparate Aminotransferase (AST) and total protein levels of infected sheep were decreased as a result of increase in the intensity of infection. A decrease in R.B.C. counts, Haemoglobin, Packed cell volume and lymphocyte counts was observed both in experimentally and naturally infected slaughtered sheep. However, an increase in total leukocytic count (TLC) alongwith an increase in the ratio of neutrophils, eosinophils and basophils was observed. At the end of experiment infected sheep gained 5.71 Kg/head less body weight and produced 4 3 grn less wool as compared with non-infected group. Based on epidemiological information the suggestions for control of the, trichostrongylid infection are submitted alongwi th recommendations for further studies. Availability: Items available for loan: UVAS Library [Call number: 0595,T] (1).

9. Comparative Prevalence And Chemotherapy Of Pasciolosis In Cattle Of Lahore And Attock Areas

by Tahir Hamid | Dr. Muhammad Sarwar Khan | Dr. Haji Ahmad | Dr. Muhammad Athar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 2002Dissertation note: This project was designed to study the comparative prevalence of fasciolosis in cattle in two different areas (plane area and sub-hilly area) having different climatic and environmental conditions in terms of temperature, humidity, rain fall and water resources etc. For the purpose, Lahore and Attock were selected. In this present study, the efficacy of newly introduced homeopathic drug "Trematox" against fasciolosis in cattle was determined by comparing it with nitroxynil (Trodax 34%) and Albendazole (Farbenda 10%). The prevalence was observed in such a way that at both the places i.e. Lahore and Attock, the animals were examined to select 80 positive cases (40 at Lahore and 40 at Attock). Subsequently, the animals were divided into 8 groups i.e. A, B, C, D, E, F, G and H. Groups A, B, C and D were kept at Lahore and groups E, F, G and H were kept at Attock. Groups A and E were untreated control groups. The eggs per gram (EPG) counts are estimated by using McMaster technique at day zero (before medication) and day 7. Then groups B&F, C&G, D&H were treated with Nitroxynil, Albendazole and Trernatox, respectively. Nitroxynil and Albendazole were used @ 10 mg/kg body weight each. The Homeopathic drug "Trematox" was injected 5 ml to each animal i/rn. At day 7, post-medication the EPG was measured. It was observed that at 7th day Nitroxynil showed the efficacy of 92.49%, Albendazole 77.77% and Trematox 42.75%. No side effects in any animal were observed during the experiment. Hence Nitroxynil, Albendazole and Trematox were concluded to be the safe drugs against fasciolosis in cattle. It was observed that medium temperature between 10-25°C and high humidity offer optimal conditions for the occurrence of fasciolosis. Availability: Items available for loan: UVAS Library [Call number: 0757,T] (1).

10. Effect Of Prophylactic Measures Against Coccidiosis In Broiler Breeder Chicks

by Imtiaz Ahmad | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahmad | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2001Dissertation note: The experiment was designed to study the effect of coccidiosis vaccine in comparasion with chemo-prophylactic and therapeutic measures against coccidiosis and their effect on weight gain, mortality and blood parameters in broiler breeder birds. For this purpose one hundred and twenty day-old broiler breeder chicks were obtained from local market and reared in the Experimental room of the Medicine Section, College of Veterinary Sciences (CVS), Lahore under standard managemental conditions upto 49 days of age. The birds were fed on commercial coccidiostat free feed purchased from the market The following materials (vaccines, medicine, caeca) were used 1. Local vaccine (Eimeria vaccine) was obtained from Parasitology Laboratory, CVS., Lahore. 2. Imported vaccine (Immucox; Vetec Laboratories, Canada) was purchased from the market. 3. Amprolium 60% was purchased from Grace Pharma, Lahore. 4. The infected caeca of broiler chicks was obtained from different farms and diagnostic laboratories. One hundred and twenty day-old broiler breeder birds were divided into eight groups comprising of 15 birds in each group. Different groups were arranged according to the following pattern: Group A. was non-infected control group, group-B was infected control group. Infection was given on day 22, group-C was vaccinated infected group. Local vaccine was given on 3rd and 10th day of age followed by the dose of 30,000 sporulated oocyst at 22nd day of age. Group-D was vaccinated with local vaccine (non infected). Group-E was vaccinated infected group. Imported vaccine was given at 7th day followed by infection at 22nd day. Group-F was vaccinated with imported coccidial vaccine, non-infected group. Group-G was infected and treated group. Infection was given on day 22 of age and the birds will be treated with Amprolium 60% at the dose of lg/2 litre of drinking water for 5 consecutive days. Group-H was non-Infected, treated with Amprolium 60% at the dose of lg/2 litre of drinking water for 5 consecutive days. The weight of birds was weekly recorded starting from day one upto the end (42nd day) of the experiment. Faecal examination for the counting of oocyst per gram of faeces were recorded after every 4th day of the administration of infection. It was observed that the performance of the birds of group D (noninfected, vaccinated with local vaccine) was the best as compared to all other experimental groups. However, group E (infected, vaccinated with Imported coccidial vaccine) was also given good performance. Availability: Items available for loan: UVAS Library [Call number: 0850,T] (1).

11. Clinico-Biochemical Studies On Detomidine Analgesia And Effects Of Its Combinatios On Animals

by Muhammad Arif Khan | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahmad | Dr. Khalid Pervez | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2003Dissertation note: The overall objective of this study was to evaluate the newly introduced imidazole derivative, drug "detomidine" with alpha-2 adr2noceptor binding properties, and its various combinations in animals. A clinico-hiochemical study was carried out to explore the various aspects of a novel sedative and analgesic drug. Analgesia was evaluated by performing castration in small ruminants, rumenal fistulization in large ruminants, skin prick test, electric stimulation, and developing an experimental colic model in donkeys. The parameters used to evaluate analgesia revealed that detomidine has greater potential to lessen the pain during minor and major surgical interventions in different animals. However, its local usage to achieve paravertebral and epidural analgesia proved that detomidine produces general effect after getting into the circulation and very poor local effect. It has been concluded that the drug can be used as preanaesthetic with chloral hydrate and pentothal sodium anaesthesia to perform major surgical exercises in equine and canine respectively. In addition it has an edge over other sedative drugs on account of its undetrimental effect on various physiological parameters of the animals. Clinical trials have proved that detomidine "a novel sedative and analgesic" is a drug of choice for restraining, examination, and minor and major surgical manipulations on equine, bovine, caprine, ovine and canine species without any untoward effects. Availability: Items available for loan: UVAS Library [Call number: 0867,T] (1).

12. The Impact Of Community Based Animal Helth Services Delivery System On Epidemiological Parameters And Farmer'S

by Farrukh nazir | Dr. Muhammad athar khan | Dr. Haji ahmad hashmi | Dr. Muhammad.

Material type: book Book; Format: print Publisher: 2006Dissertation note: A study was conducted to understand the impact of community based animal health services delivery systems on epidemiological parameters and farmer's economic sustainability in Central Punjab. In Pakistan three systems for the animal health services delivery are being practiced without any data base and conclusive findings for the comparison purposes and in terms of the replication if needed in future, therefore, a study was planned to quantify and compare the three systems. These systems are; community based, public based and conventional based animal health services delivery systems. As the community based system was launched as Halla scheme, in Central Punjab through the German Technical Cooperation program / funding. Therefore, the other two systems i.e. public and conventional based were selected in the areas adjacent to the community based system (Halla Cluster). The project area was selected because of the similar geographical, environmental, socio cultural and political similarities. One cluster of five villages was selected randomly for each system. The data was obtained from each cluster through active disease surveillance and was recorded on a questionnaire. Each questionnaire was used for one farmer. The cluster of five villages was 'considered as one herd. In the 1st project, the clusters were quantified and compared on different parameters, like provision of animal health services, provided from the system to the member farmers. Epidemiological parameters like morbidity and mortality rate were recorded and analyzed statistically. In the 2IId project, the community trials were also conducted to compare the efficacy of prophylactic interventions, for the economically important diseases of buffaloes and cattle i.e. the haemorrhagic septicaemia and foot and mouth disease. The effect of deworming was also recorded with reference to morbidity and mortality. In the third project the sustainability of the farmers residing in the systems were compared in terms of cost benefit ratio. Animal health services were arranged like vaccination, treatment, deworming, artificial insemination and nutrition support. Poor, good and better services were provided in conventional based, community based and public based animal health services delivery systems, respectively. The impact of services on morbidity and mortality was recorded, the minimum morbidity and mortality rate was recorded in the community based system and moderate and maximum morbidity rate, mortality rate, number of outbreaks and fertility rate due to various diseases were recorded in the conventional based animal health service delivery system. The results were statistically analyzed and significant difference at a level 5% was estimated. The efficacy of the vaccination was estimated and it was statistically found that the morbidity and mortality rates were significantly low in the intervention herds of buffaloes and cattle, as compared to non intervention herds. The overall sustainability of the farmer in term of cost benefit ratio was higher in community based as compared to public based and conventional based animal health services delivery system. In conclusion the better the animal health services delivery system, the more prosperous was the farmer. So, it is recommended that the community based animal health service system be promoted and replicated on priority basis. The animal health services are provided by public based service deliverers but they are not of the same quality as were provided by the community based system in Halla Cluster. This is the reason that in spite of all the services provided by the public based system, the morbidity rate and mortality rate due to various infectious and non infectious diseases were higher in buffaloes and cattle as compared to the community based system. In conventional based system neither the community based services nor the public based services were available for the farmers because those areas were remote and far from the public veterinary hospitals. Therefore, the morbidity rate and mortality rate at the highest spectrum of ranking and disease burden/disease load. The magnitude of disease problems was highest in the conventional based, lowest in the community based system and intermediate in the public based system. Better the quality of services are provided the minimal are the losses due to the diseases in the animal populations and in turn better the cost benefit ratio and ultimately the more prosperous is the farmer. The only way of poverty alleviation in the rural communities is to replicate the community based animal health services delivery system (Halla) with certain modifications in the Provinces of Punjab and Sindh in particular and in North West Frontier Province and Balochistan in general Availability: Items available for loan: UVAS Library [Call number: 1147,T] (1).

13. Clinico-biochemical Studies on Detomidine Analgesia and Effects of its Combinatios on Animals

by Muhammad Arif Khan | Prof. Dr. Muhammad Ashraf | Dr. Khalid Pervez | Dr. Haji Ahmad Hashmi.

Material type: book Book; Literary form: not fiction Publisher: 2003Dissertation note: The overall objective of this study was to evaluate the newly introduced imidazole derivative, drug "detomidine" with alpha-2 adr2noceptor binding properties, and its various combinations in animals. A clinico-hiochemical study was carried out to explore the various aspects of a novel sedative and analgesic drug. Analgesia was evaluated by performing castration in small ruminants, rumenal fistulization in large ruminants, skin prick test, electric stimulation, and developing an experimental colic model in donkeys. The parameters used to evaluate analgesia revealed that detomidine has greater potential to lessen the pain during minor and major surgical interventions in different animals. However, its local usage to achieve paravertebral and epidural analgesia proved that detomidine produces general effect after getting into the circulation and very poor local effect. It has been concluded that the drug can be used as preanaesthetic with chloral hydrate and pentothal sodium anaesthesia to perform major surgical exercises in equine and canine respectively. In addition it has an edge over other sedative drugs on account of its undetrimental effect on various physiological parameters of the animals. Clinical trials have proved that detomidine "a novel sedative and analgesic" is a drug of choice for restraining, examination, and minor and major surgical manipulations on equine, bovine, caprine, ovine and canine species without any untoward effects. Availability: No items available Checked out (1).



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