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1. Anthelmintic Efficacy Of Caesalpinia Crista, Ivermactin, Levemisole And Oxfendazole Against Toxocara Vitulorum

by Saeed Ahmad sindhu | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahimad | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1993Dissertation note: The present project was designed to test the anthelmintic efficacy of Caesalpinia crista Linn. seed (Karanjwa) at different dosage levels against Toxocara vitualorum infection in buffalo calves. During the both phases of first experiment, anthelmintic efficacy of Caesalpinia crista Linn. seed (powder) was tested at different dosage levels but anthelmintic efficacy was not observed at the dosage levels ranging from 2 gm to 6 gm/kg body weight. It was concluded in the first experiment that Caesalpinia crista Linn. seeds have no anthelmintic efficacy against Toxocara vitulorum infection in buffalo calves. During the second experiment clinical trials were conducted to test the anthelmintic efficacy of Caesalpinia crista Linn. seeds (Karanjwa), Ivermectin (Ivomec), Levamisole (Anthelmine) and Oxfendazole (Systarnex) against Toxocara vitulorum infection in buffalo calves under field conditions. Again results of second experiment support the zero percent (0%) anthelmintic efficacy of . crista Linn seeds (Powder) at the dosage level of 4 gm/kg body weight against vitulorum in buffalo calves. Anthelmintic efficacy of Ivermectin. (Ivomec, I ml/50 kg body weight), Levamisole (Anthelmine 1 ml/15 mg body weight) and oxfendazole (systamex 1 ml/5 kg body weight) was observed to be 99.30%, 98.30% and 100% respectively against Toxocara vitulorum infection in buffalo calves. Availability: Items available for loan: UVAS Library [Call number: 0360,T] (1).

2. Prevalence Of Lungworm Infestation (Dictycaulus Spp.) And Its Effect On Some Blood Parameters Of Camels During Months Of October December.

by Aslam, M | Dr. Muhammad Sarwar Khan | Dr. Asif | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1995Dissertation note: Camel is a versatile creature of the nature. Its population in Pakistan is 9,58,047 heads. Its importance is obvious from the facilities which it provides to the mankind e.g. transportation and ploughing facilities, lifting of water and pulling of carts, provision of milk meat and earning of foreign exchange. But on the other hand, camel is ignored in provision of better managemental facilities due to which it is facing many disease problems. Similarly, camel is also ignored by our scientists and a little research work has been done on camel in the world. Keeping in view all these factors, this project was designed to see the prevalence of lungworm infection in camel. This study also included haematological changes in camel blood suffering from lungworm infection. This study was conducted during the months of OctoberDecember, 1993 at Lahore abattoir. For the prevalence of lungworm infection, 150 camels suspected for lungworm infection were selected and their faecal and blood samples were collected. Regarding the prevalence of lungworm infection through faecal examination the results of present investigation show that occurrence of lungworm infection in camels is 6.00%, i.e. 9 camels out of 150 suspected were found positive. The mean values of haematological examination were observed i.e. Total leukocytic count (31.62 thousand/cm.mm), Differential leukocytic count - Neutrophils 67.88%, Eosinophils 28.77%, Basophils 3.66%, Lymphocytes 65.88%, Monocytes 5.55%, and ESR 12.20 mm/hour. Blood of camels negative to lungworm infection showed total leukocytic count mean value 19.30 thousand/cu.mm, Differential leukocytic count - Neutrophils 47.00%, Eosinophils 8.88%, Basophils 1.88%, Lymphocytes 38.55%, Monocytes 4.22% and ESR 1.85 mm/hour. Availability: Items available for loan: UVAS Library [Call number: 0405,T] (1).

3. Estimation And Correlation Of Protein, Differential Leukocyte Count (Dlc) And Total Leukocyte Count (Tlc) In The Blood And Milk Of Sub Clinically Mastitic Buffaloes

by Fakhar uz Zaman | Dr. Mohammad Sarwar Khan | Dr. Khalid Pervaiz | Dr. Shakil | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1994Dissertation note: One hundred milk samples from mastitic buffaloes brought for treatment to outdoor Ward of the College of Veterinary Sciences, Lahore and adjacent areas were examined for their total blood protein, total blood leukocytic count, blood differential leukocytic count, milk whey protein, milk total leukocytic count and milk differential leukocytic count. Total protein, total leukocyte count, neutrophils, lymphocytes, monocytes, eosinophils and basophils in blood gave their average as 6.84 gm/100ml, 4036 cells/mi, 48.17%, 48.32%, 2.34%, 0.69% and 0.48% respectively. Total whey protein, total leukocytic count, neutrophils, lymphocytes, monocytes, eosinophils and basophils in milk showed their average values as 1.02 gm/l00ml, 4665000 cells/mi 70.42%, 24.19%, 3.45%, 1.30% and 0.37% respectively. Correlation between blood and milk protein, total leukocytic count, neutrophils, lymphocytes, monocytes, eosinophils and basophils were estimated as -0.929, 0.962, 0.952, 0.985, -0.203, 0.060 and 0.284 respectively, which gave an increase of total whey protein, neutrophils in blood, neutrophils in milk and milk total leukocyte count and decrease of total blood protein, total blood leukocytes and lymphocytes in milk and blood. Availability: Items available for loan: UVAS Library [Call number: 0406,T] (1).

4. Effect Of Hydatid Cyst On Different Blood Components In Camels Of Different Age Groups

by Hameed ur Rehman | Dr. Muhammad Sarwar Khan | Dr. Khalid Pervaiz | Dr. Shakil | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1995Dissertation note: The present project was designed to find out the prevalence of hydatidosis in different age groups of camels and to see its effect on some blood parameters (TEC, Hb, PCV) and also to examined the same blood parameters of control groups. For this purpose study was carried out on 300 camels of various age groups (2-3 years, 3-5 years, and above 5 years) brought to Lahore abattoir for slaughtering purposes during the period from July 1994 to September 1994. The results showed that out of 300 camels, 189 (63%) were positive for hydatidosis. It revealed that infection rate was higher in Group-Ill (above 5 years) 70%, than in Group-I (58%) and Group-Il(61%). The study also revealed that the prevalence of hydatidosis was 67.68% in July, 54.9% in August and 66.67% in September The present investigation also showed that a mean of total erythrocyte count was 8.667 million/microliter with range of 6.00 million/microliterto 11.101 million/microliter, Haemoglobin concentration was 10.00 g/100ml with a range of 6.3 g/100 13.1 g/l00ml and mean of packed cell volume was 31.7 with a range of 20.00% to 39.00%. The control blood samples of 189 camels showed mean of total erythrocyte was 9.721 million/microliter ranging from 6.32 million/microliter to 12.92 million/microliter, mean of haemoglobin concentration was 11.5g/100ml with a range of 7.3 g/100ml to 14.4g/100ml and packed cell volume was 33.4% with a range of 22.00% to 40.7% Availability: Items available for loan: UVAS Library [Call number: 0413,T] (1).

5. Effect Of Glucocorticoids Alongwith Antimicrobial Drugs Against Haemorrhagic Septicaemia In Buffalo

by Ramzan, M | Prof.Dr.Muhammad Ashraf | Dr. Khalid Pervaiz | Dr. Muhammad | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1995Dissertation note: Two long acting antibiotic preparations of oxytetracycline and amoxicillin were used in these trials against Haemorrhagic Septicaemia, singly and alongwith a combination of synthetic glucocorticoids (Dexamethasone and prednisolone). Eighty buffalo calves suffering from Haemorrhagic Septicaemia were selected and treated under field conditions. Weighted clinical score was recorded before and after treatment in each case, on the basis of severity of clinical symptoms. Reduction in this score and recovery or death of animal was also noted. It was concluded that amoxicillin was more effective than oxytetracycline and the addition of glucocorticoids reduced the convalescence period and also increased the survival rate. Therefore long acting amoxicillin alongwith Dexamethosone and prednisolone is recommended as the successful therapy for Haemorrhagic septicaemia. Availability: Items available for loan: UVAS Library [Call number: 0420,T] (1).

6. Effect Of Routine Deworming On The Development Of Resistance Against Git Nematodes In Sheep

by Akram, M | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahmad | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1994Dissertation note: In this project the effect of routine deworming on GIT nematodes in sheep was studied with particular reference to the development of drug resistance. Comparison was studied by treating the flocks where routine deworming was practiced with the levamisole and albendazole and where routine deworming was not practiced with any medicine. One twenty sheep positive for GIT nematodes infection were selected. They were divided into six groups A, B, C, D, E and F comprising of 20 animal in each group. Animals of group A, B, C were selected from two different floclwhere routine deworming was practiced with levamisole and albendazole respectively. Animals of group D, E, & F were selected from unregistered private flocl where routine deworming was not practiced. Rectal faecal samples were collected before medication and at the seventh day of medication from all the six groups of sheep to count the eggs per gram of faeces and to count the number of larvae after culture under laboratory conditions. Groups A & D were treated with the levamisole orally at the dosage rate of 7.5 mg/kg. Groups B and E were medicated with albendazole orally at the dosage rate of 5 mg/kg and groups C & F were kept as control and remained untreated. Then the efficacy of levamisole and albendazole in addition to the development of resistance against these anthelmintics was estimated. Experimental study revealed that the levamisole showed 98.73% efficacy in the first timely dewormed flock and no any resistance was recorded whereas, 72.55% efficacy was noticed in the regularly dewormed flock, with a slight resistance. Albendazole had 97.13% efficacy in the first timely dewormed private flock and 61.24% efficacy in the regularly dewormed flock. This shows a strong evidence of resistance in the albendazole treated flock. No side effect were observed in both the groups. Levamisole was found better dewormer with less chances of resistance. However, both drugs can be used safely to achieve control of nematode parasites in sheep. Availability: Items available for loan: UVAS Library [Call number: 0421,T] (1).

7. Efficacy Of Ivermectin And Coumaphos Against Ectoparasites In Cattle And Buffaloes

by Nadeem Haider, Syed | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahmed | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1995Dissertation note: The project was designed to find out the efficacy of ivermectin and Coumaphos against ectoparasites in cattle and buffaloes. Thirty buffaloes infested for ectoparasites were selected for the treatment trials and divided into three groups i.e. Bi, B2 and B3 having ten animals in each group and thirty cattle infested for ectoparasites were selected for the treatment trials and also were divided into Cl, C2 and C3 groups. The comparative acaricidal drug trials were conducted on 20 infested animals against ectoparasites of group BI and Cl having ten animal in each were medicated with Ivermectin (lvomec: MSD) injected once by s/c route at dose rate of 200 pg/kg body weight. Observation were made on 7th and 14th day post-medication. Skin scrapping examination was done. The overall efficacy of invermectin on 7th and 14th day in buffaloes was 40% and 80% and in cattle 50% and 90% respectively. The comparative acaricidal drug trials were conducted on 20 infested animals for ectoparasites of B2 and C2 having ten animals in each were treated with Coumaphos (Asuntol: Bayer) at the dose rate of 30-50 gm/animal. On the 7th and 14th day post medication skin scraping examination was done. The efficacy of Coumaphos on 7th and 14th day in buffaloes was 50%, 50% and in cattle 70%, 70% respectively. Animals were also observed for any side effect of both medicine. No side effects were observed during the period from treatment to last observation in any group i.e. groups BI, Cl and B2, C2 groups. On last observation no spontaneous recovery was noted. In B3 and C3 in untreated and control groups. From the results of present study it is concluded that Ivermectin (Ivomec MSD) is the drug of choice for the treatment of ectoparasites in cattle and buffaloes when it is given at the dose rate of 0.2 mg/kg body weight by subcutaneous injection. Availability: Items available for loan: UVAS Library [Call number: 0422,T] (1).

8. Effect Of Fascioliasis On The Blood Picture And Comparative Efficacy Of Different Fasciolicidal Drugs In Sheep

by Shazia Maqbool | Dr. Khalid Pervaiz | Dr. Mubasher | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1995Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0471,T] (1).

9. Helminthiasis: Its Dissemination And Treatment With Fenbendazole In The Migrating Sparrows

by Ali Razmaara, Syed | Dr. Muhammad Athar Khan | Dr. Haji Ahmad | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Nature of contents: biography; Literary form: Publisher: 1995Dissertation note: The present study was conducted to bust upon the worm load in the naturally parasitized migratory sparrows, and also to determine the effect of worm load on the blood picture. Furthemore the effect of broad spectrum anthelmintic like Panacur (fenbendazole) in the experimental group in terms of eggs per gm. of faeces pre and post medication. For this experiment 400 live migratory sparrows were purchased randomly, out of which 200 birds were slaughtered and an incidence of 64.5% parasitic fauna was found. Sparrows were found infected, with two species of nematode i.e. Ascaridia gaul was 39.5% and Heterakis gallinarum was 25% respectively. None of the bird was found infected with trematode and cestode. The hematology of the above 64.5% parasitized sparrows was performed. The study revealed that due to nematode infection there was a slight increase in Total leucocytic count and Heterophils whereas the Total erythrocytic count, Haernoglobin level, Lymphocytes and Eosinophils were decreased which may lead to anemia, loss of growth and production. From the left 200 wild naturally parasitized sparrows, 86 (43%) birds were found positive. These sparrows were divided into two groups one was left as control and the other group was subjected to drug efficacy. Panacur (fenbendazole) at the rate of 9.9 mg/kg body weight which was given orally. The results were observed in terms of eggs per gm. of faeces pre and post medication after 24, 48 and 96 hours respectively. The control group showed progressive increase in ova count i.e. 12.82%, 24.79% and 48.72% respectively, whereas reduction in the ova count of the medicated group was gradually observed as 83.72%, 92.25% and 95.35%. The poultry breeders and scientists are urged to make an effort how the wild birds could mechanically transmit the parasites from one region to another. An attempt should also be made for the better understanding of bacterial and viral infections dissemination. Availability: Items available for loan: UVAS Library [Call number: 0474,T] (1).

10. A Serological And Coprological Study Of Paramphistomiasis In Buffalo

by Jameel Ahmad | Dr. Khalid Pervaiz | Dr. Haji Ahmed | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1997Dissertation note: Two hundred faecal samples, serum samples and paramphistomes used in the present study collected from main slaughter house of Lahore and from surrounding of the city. Faecal examinations were carried out with fresh smear technique and 61.5% animals found positive for paramphistomiasis. Serum was separated from the blood samples collected from infected and suspected buffaloes for the performance of enzyme-linked immunosorbent assay. Paramphistome crude antigen was prepared from fresh stomach flukes, which contained 95.66 mg proteins/mi at 545 nm. For performing the enzyme linked immunosorbent assay, the 96 well ELISA plates were coated with crude antigen & kept overnight & then the other procedure for the assay was followed, & the serum samples were tested with paramphistome crude antigen. In positive samples, the yellowish-brown colouration was formed. In faecal examination, 61.5% and in the ELISA 100% of the animal found positive. From the conclusion of the results if was found that ELISA (100%) has given more positive results then faecal examination (61.5%). Availability: Items available for loan: UVAS Library [Call number: 0490,T] (1).

11. Comparative Efficacy On Newly Introduced Antibacterial Drugs Against Experimentally Induced Escherichia Coli

by Zubair, M | Dr. Khalid Pervaiz | Dr. Mubasher | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1996Dissertation note: Pakistan faces an acute shortage of animal protein which is acknowledged as a serious problem at national level. Since broilers are the fastest converters of crude protein into digestible high quality protein for human consumption. There is much need in the production of broilers for the said reason in Pakistan. The upgrading of poultry industry is suffered from huge losses caused by certain diseases of bacterial origin. Amongst bacterial diseases, Escherichia coli is the worst threat to poultry industry. Therefore, concrete and consistent effort was done in this project to control the Eschericia coli infection. The present project was done to study the efficacy of different drugs on prevalent strains of E. coli isolated from broilers that were collected from Diagnostic Laboratory, office of the Project Director, Poultry Production, 16-Cooper Road, Lahore and various Farms in the vicinity of Lahore. Six different antibacterial drugs which comprised of avitryl, advocin, plasmacolin, flumequine gentamicin and inoxyl were used to check the sensitivity of the isolates. In-vitro the sensitivity results was in this order avitryl, advocin, plasmacolin, gentamicin, flumeuine and inoxyl respectively. Avitryl emerged as best drug. The pathogenicity of the isolated strains was tested in albino mice taken from V.R.I., Lahore. The confirmed pathogenic isolates of . coli were diluted upto 3x108 bacteria per 0.25 ml, this dilution ws made after doing total viable count and the dose was injected intra-peritoneally to five albino mice while 5 albino mice were kept as controls. These six drugs were further tested for their efficiency in broilers against . coli infection. A total of two hundred and forty birds reared upto four weeks of age and then they were divided into eight groups, A, B, C, D, E, F, G and H, each having 30 birds. Group H was kept as non-infected and non- treated. While Group G was infected but not treated. The remaining groups A, B, C, D, E and F, 16 hours after infection were treated with avitryl, advocin, plasmacolin, flumequine, gentamicin and inoxyl for five days respectively. All the groups were kept under close observation and their mortality and feed efficiency was noted. In group G maximum mortality was noted i.e. 57.14 while in the group A, B, C, D, E and F, the mortality recorded was 22.72, 30, 33.33, 40.90, 47.82 and 52.17 respectively. Avitryl was proved to be the highest protection against coli infection and best in relation to F.C.R. by this experiment. Availability: Items available for loan: UVAS Library [Call number: 0492,T] (1).

12. A Clinico Pathological Examination And Treatment Of Experimentally Induced Salmonella Infection In Goats

by Baig Muhammad Kakar | Dr. Khalid Pervaiz | Dr. Khushi | Dr. Mohammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1997Dissertation note: Salmonellosis is common problem for goat population of the country which is therefore, a constant threat for the farming community of the country during the summer season. The present study was undertaken to study the course of disease with relevance uo environmental factors and the efficacy of various antirnlcroblal drugs available in the market. Salmonellosis was clinically manifested by acute enteritis, dysentery, abdominal cramps, where as temperature, respiration rate and pulse rate were raised upto 2- 3.4°F, 16-23 times/minute and 10-16 times/minute respectively. Predominant postmortem lesions were dehydration, petechiation of the intestinal mucosa occasionally with the accumulation of reddish fluid in t1e intestinal lumen, thickening of the urinary bladder and Pale carcase along with decreased serum sodium concentration in such animals. Among the various antimicrobial drugs used invitro, Gentamycin and chloraphenicol were highly sensitive where as Oxytectracycline, trimethoprim apicillin and kananycin were quite sensitive. Results of in vivo traits for oxytetracycline, tribrissen, gentamycin were 0.00%, 80%, 80% and 100% respectively, whereas 100% mortality was recorded in untreated control group of animals. Availability: Items available for loan: UVAS Library [Call number: 0494,T] (1).

13. Efficacy Of Three Different Drugs Against Ectoparasites In Naturally Infested Dogs And Their Effect On Blood Parameters

by Sharoon Sabir | Prof.Dr.Muhammad Ashraf | Dr. Khalid Pervaiz | Dr. Mubsher | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1996Dissertation note: The present study was designed to evaluate and compare different drugs in 40 naturally infested dogs (based on skin scrapping examination) taken from Dog Hospital, College of Veterinary Sciences, Lahore and different Pet Clinics. Ivomec, Neguvon and Sulphur Tar Oil were used in three groups while one was control group. Treatment in each group was repeated after 14 days. Blood parameters i.e. Hemoglobin Estimation (Hb), Packed Cell Volume (PCV), Total Erythrocytic Count (TEC) and Total Leucocytic Count (TLC) were estimated. Results of treatment were evaluated on 14 days and 21 days after the first treatment on basis of skin scrapping examination and improvement in clinical symptoms. Efficacy of ivermectin, trichiorophon and sulphur tar oil was 80%, 70% and 40% on 14th day after 1st treatment. Same results were observed one week after second treatment indicating no additional benefit.Based on these observations it was concluded that ivermectin (200 µg/kg, s/c) was safe to use and its efficacy was significantly higher than Neguvon and Sulphurate oil. Moreover a single injection is sufficient for mild cases of ectoparasites but in severe cases second injection may be repeated after 14 days interval. Availability: Items available for loan: UVAS Library [Call number: 0508,T] (1).

14. Prevalence Of Puff Disease In Horses With Biochemical And Chemotherapeutic Studies

by Shamoon ur Rashid | Dr. Muhammad Sarwar Khan | Dr. Javed | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1997Dissertation note: This project was designed to find out the prevalence of puff disease in horses in Lahore area. This study also included chemotherapeutic effect of two different treatments and biochemical studies. This study was conducted during the month of July-September, 1996 at Outdoor Hospital, College of Veterinary Sciences, Lahore and around the city of Lahore. For the prevalence of puff disease 290 horses were examined and their clinical signs were observed. Investigation showed that the occurrence of puff disease in horses was 12.14% i.e. 36 horses out of 290 were found positive. Thirty positive cases were treated with two different groups of treatments. With 1st group of treatment 5 horses were cured completely and with 2nd group of treatment 11 horses were cured completely. The results of treatment were based on the reversal of clinical signs. Serum samples of positive horses were also observed before and after treatment for the detection of glucose, cholesterol and chloride levels. Availability: Items available for loan: UVAS Library [Call number: 0536,T] (1).

15. A Clinico Epidemiiological Study Of Bacterial And Parasitic Causes Of Respiratory Syndrome In Sheep And Goats

by Waseem Shahzad | Dr. Khalid Pervaiz | Dr. Khushi | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1997Dissertation note: In Pakistan sheep and goats production is playing a very important role in bridging the protein gap among our population. Sheep and goats not only provide us high quality meat for our consumption but also wool fibre and high quality leather. In Pakistan every year there is lot of mortality due to respiratory tract infections in sheep and goats especially due to pneumonia which results from a variety of causes' namely, bacterial, viral, parasitic, mycoplasmal and fungal etc. It causes high economic losses due to increased rate of mortality. This study was carried out on two hundred sheep and goats of either sex including all age groups brought to out door hospital of College of Veterinary Sciences, Lahore during February 1997 to June 1997. In the present study isolation and identification of bacterial and parasitic etiological agents of the respiratory tract problems in sheep and goats was carried out. According to this study many bacterial agents causes respiratory problems in sheep and goats, out of 132 positive nasal samples Pasteurella multocida was isolated from 32 (24%), . haemolytica 43 (33%), Corynebacterium 26 (20%), 23 (17%), Streptococcus 18 (14%) and Escherichia ççjj 20 (15%) from affected sheep and goats. Similarly many lungworms cause respiratory problems, out of 82 positive faecal samples Dictvocaulus filaria was isolated from 76 (92.6%) and Protostrongvlus rufesence 6 (7.3%) from affected sheep and goats. The haematological study of the infected and non infected animal showed that there were decreased values of total erythrocytic count, packed cell volume and differential leucocytic count and increased values of total leucocytic count and erythrocytic sedimentation rate of affected animals. Availability: Items available for loan: UVAS Library [Call number: 0539,T] (1).

16. Comparative Efficacy Of Oxyclozanide, Rafoxanide And Bithionol Sulphoxide Against Paramphistomiasis In Buffaloes

by Umar, M | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahmad | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1998Dissertation note: The present project was designed to test the anthelmintic efficacy of oxyclozanide, Rafoxanide and Bithionol suiphoxide against paramph istomiasis in naturally infected buffaloes. The comparative anthelmintic trials were conducted among Nilzan drench - Id (Oxyclozanide 3.0% + Levamisole 1.5%,), Fasifree - Prix (Rafoxanide 30 mg/mI), Irchasol - Medivet (Bithionol sulphoxide 10% + Levamisole 1.5%) and Nilverm drench - ICI (Levamisole 1.5%) against paramphistomiasis in buffaloes. Seventy five naturally infected buffaloes were selected and divided into five equal groups i.e. A, B, C, D and E containing 15 animals each. Each animal of group A was given Nilzan drench (lml/2kg body weight), group B was given Fasifree (lml/4kg body weight), group C was given Irchasol (lml/2kg body weight), group D was given Nilverm (lml/2kg body weight), while group E was kept as control. The efficacy of anthelmintics was evaluated by counting eggs per gram (EPG) of faeces on day 7, 14 and 21 post-medication. The mean efficacyh of Nilzan drench was 97.29%, mean efficacy of Fasifree was 98.5% and of Irchasol was 85.56% while Nilverm did not have any effect for the treatment of Paramphistomiasis in buffaloes under field conditions. Availability: Items available for loan: UVAS Library [Call number: 0547,T] (1).

17. Prevalence Of Mixed Infection Of Nematodes And Trematodes In Camels At Lahore And Their Effect On Blood Picture

by Asif, M | Dr. M. Sarwar Khan | Dr. Khalid Pervaiz | Dr. M. Afzal | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1998Dissertation note: The present project was designed to know the prevalence of mixed infection of Nematodes and Trematodes in camels at Lahore and the effect of this condition on different blood parameters. The source of camels was Lahore Abattoir. A total of 200 camels were examined from June 1998 to September 1998. Fecal samples were taken from the camels and at the same time blood samples were also taken from the same camel. Fecal samples were examined at Central Diagnostic Laboratory. Medicine Section, and College of Veterinary Sciences Lahore. Fecal samples were examined by the direct smear examination and salt floatation method. Camels were divided into four groups, group A. camels positive for any nematode, liver fluke and paramphistome, group B. camels positive for liver fluke and nématode, group C. camels positive for paramphistome and nematode and an other group D was comprised of camels declared negative I or above mentioned helminthes. The blood samples of only those camels were subjected for examination, which were declared positive for any of the three groups. The prevalence of group A camels was 2.5% and highest prevalence of these camels was observed in the months of June and September. The prevalence of group B was 8 %. and of group C was 3 %. The overall prevalence of nematodes and treniatocles was 70 0o. Only 30 % camels were free of these helminthes. I3lood examination conducted for group A revealed increased Total leukocyte count average was 44000/cubic mm. and range was 40000-48000/cubic nun. Average T.E.C was 3.9 M/cubic mm. and Hh. 11 gm!dl., range for T.E.C 3.6- 4.3 M/cubic mm and I-lb.. was 9-l3gm/dl. D.L.C revealed average neutrophils 75%, lymphocytes 25% and range in neutrophils was 73-77% and lymphocytes were 23-27%. Blood examination conducted for group B revealed increased Total leukocyte count average was 38000/cubic mm. and range was 33000-42000/cubic mm. Average T.E.C was 4.4 M/cubic mm. and Hb. 11.2 grnldl.. range for T.E.C 4- 4.8 M/cubic mm and I-lb. was 8-l3gm/di. D.LC revealed average neutrophils 70%, lymphocytes 28% and range in neutrophils was 68-73% and lymphocytes were 26-30% average monocytes were 2.1% and range was l-S%. Blood examination conducted for group C revealed increased Total leukocyte count average was 35000/cubic mm. and range was 28000-39000/cubic mm. Average for T.E.C 4 M/cubic mm. and Hb. 10.5 gm/dl.. range for T.E.C 3.8-4.5 M/cubic mm and Hh., was 8.8-1 1.7 gm/dl. D.L.C' revealed average neutrophils 75%, lymphocytes 24.6% and range in neutrophils was 74-77% and lymphocytes were 23-26% average range of monocyte was 0.3%, 0-1% respectively. Blood examination conducted for group D revealed increased Total leukocyte count average was 156000/cubic mm. and range was 13900-20000/cubic mm. Average for T.E.C 5.27 M/cuhic mm. and fIb. 14.6 gm/dl., range for T.E.C 4.9-5.6 M/cubic mm and Fib., was 12-l6gm/di. D.L.C revealed average neutrophils 6.8%, lymphocytes 28.4% and range in neutrophils was 65-72% and lymphocytes were 25-3O% for monocytes and eosinophil average was 1.8%, 0.8% and range was 0-3°/o,0-25 respectively. Availability: Items available for loan: UVAS Library [Call number: 0572,T] (1).

18. Epidemiology And Economic Losses Of Trichostrongylid Parasites In Sheep

by Sarwar Khan, M | Dr. Muhammad Athar Khan | Dr. Haji Ahmad | Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1997Dissertation note: The meteorological data recorded during the study period from 1.1.96 to 31.12.96 showed the maximum temperature in June as 36.5°C and minimum temperature in December as 6.8°C. Maximum and minimum Humidity was recorded in the month of September and April as 85% and 55% respectively. The maximum rainfall during the year was recorded in the month of August as 660 mm. The faecal egg counts of sheep grazing on permanent pasture showed the minimum EPG during first week of January while maximum EPG on nid of September and first week of October. Pasture larval counts were performed on permanent pasture and experimental plot for the recovery of trichostrongylid larvae. The maximum number of larvae was recovered on 16th September, 1996, while minimum number was recovered in January and February from permanent pasture and experimental plot respectively. Two species of trichostrongylids were identified i.e. Haemonchus contortus and Trichostrongvlus colubriformis. The faecal and larval counts were very low in the months of January and February, the counts started rising in March. Peak counts were seen in the month of September. Decline in counts started in late October and reached to minimum in December. Mature and immature worm counts of slaughtered sheep were performed at 15 days interval. The, overall prevalence oftrichostrongylid parasites was 34%. The maximum number of mature parasites were seen during first week of October which was886 whereas maximum number of immature parasites including hypobiotic was 326 on 1st of December. During this study the average fecundity/female of contortus and L colubriformis parasites were calculated as 721 and 209 respectively. A spring rise in worm egg counts was experienced in mid of March. A pen parturient rise in the worm egg counts of pregnant and lactating ewes indicated the maximum counts during lambing week. An experimental group of sheep with mixed infection of trichostrongylid parasites showed the similar pattern of EPG counts as of naturally infected sheep. A study was performed to evaluate any protection provided by a particular Flaemoglobin type to trichostrongylid infection hut not difference could be observed. The Asparate Aminotransferase (AST) and total protein levels of infected sheep were decreased as a result of increase in the intensity of infection. A decrease in R.B.C. counts, Haemoglobin, Packed cell volume and lymphocyte counts was observed both in experimentally and naturally infected slaughtered sheep. However, an increase in total leukocytic count (TLC) alongwith an increase in the ratio of neutrophils, eosinophils and basophils was observed. At the end of experiment infected sheep gained 5.71 Kg/head less body weight and produced 4 3 grn less wool as compared with non-infected group. Based on epidemiological information the suggestions for control of the, trichostrongylid infection are submitted alongwi th recommendations for further studies. Availability: Items available for loan: UVAS Library [Call number: 0595,T] (1).

19. Comparative Efficacy Of The Latest Antibacterial Drugs Against Experimentally Induced Pullorum Disease

by Dr . Khalid Omran, M | Dr . Khalid Pervaiz | Dr . Khushi | Dr . Mohammad Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1997Dissertation note: A total 210 birds were reared upto the age of 4 weeks and the divided into 7 groups viz A, B, C, D, E, F and G, comprised of 30 birds in each group. At the age of 28 days the groups A to E were experimentally infected with Salmonella pullorum inoculation intraperitoneally with the dose rate of '/2 ml. The group F was infected but non-medicated and the group G was kept as control (non infected and non medicated). The groups A, B, C, D, E and E were treated with Anflox, Inoxyl, Triquine, Flumiquine and Gentamycine respectively. All the groups were kept under close observation to record clinical signs, mortality rate, weight gain and feed conversion ratio. Postmortem of dead birds was also conducted. The blood parameters TEC, TLC, and DLC were also estimated post medication on 1st, 3rd and 5th day. The mortality before medication in groups A, B, C, D, E and F was 10%, 16.67, 6.67%, 13.34%, 13.34% and 6.67% respectively. While the mortality during treatment in each group was 25.92%, 32%, 39.28%, 19.23%, 46.16%, 64.28% respectively. The mortality in control group was 6.66% during these days. According to this trial Flumiquine provided maximum protection against Salmonella pullorum infection and proved best in relation to weight gain and FCR. Anflox stood second in the list while Inoxyl was the 3rd drug which provided protection against the infection, whereas Triquine and Gentamycin were the least effective drugs. The signs which appeared after 18-24 hours post infection were listlessness, ruffled feathers, droopy wings, loss of appetite, poor growth, depression, increased thirst and severe diarrhoea of chalky white color. The post mortem findings were enlarged spleen, congested liver with streaked haemorrhages, congested and distended kidneys, grey hepatization in lungs and enlarged heart. The total erythrocytic count decreased in infected non-medicated birds while in medicated groups it remained in normal range. The same was true of total leucocytic count. However, in DLC the heterophil indicated increased percentage after inoculation of infection while the lymphocytes, basophils, eosinophils and monocytes remained within range after the infection. The findings of the present study elucidate the disease and help in diagnosis and treatment of this malady. Availability: Items available for loan: UVAS Library [Call number: 0688,T] (1).

20. Prevalence And Chemotherapy Of Ascariasis In Cross-Bred Calves In And Around Lahore

by Waqar Ahmad | Dr. Muhammad Sarwar Khan | Dr. Khalid Pervaiz | Dr. Muhamad | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 2002Dissertation note: The present project was designed to find out the prevalence of ascariasis in cross-bred calves in and around Lahore and to evaluate anthelmiiitic efficacy of albendazole, oxfendazole and fumaria parviflora against ascariasis. For this purpose the faeces of 203 cross-bred calves under 3 months aged from various localities in and adjoining city of Lahore were examined for the presence of ascariasis. Forty calves were found positive. It was observed that the prevalence of ascariasis was 19.62%. Forty naturally infected calves having moderate to heavy infection were divided into 4 groups A, B, C and D, each having 10 calves. Ten calves were acted as non-infected and non-medicated (control) as group E. The anthelmintic efficacy of albendazole, oxfendazole and fumaria parviflora was studied by administering to group A, B and C respectively. The efficacy of the drug was determined on the basis of reduction in number of ova count, present in the faeces after medication. Anthelmintic efficacy of albendazole (@ 5mg/kg body weight), oxfendazole (@ 4.5mg/kg body weight) and fumaria parviflora (@ 2gm/kg body weight) was observed to be 83.67%, 95.09% and 0% at clay 5 respectively and at 10 days 99.65%, 100% and 20.15% respectively. It was found that systamex was the most effective drug for the treatment of ascariasis in crossbred calves. Second was the albenclazole. None of these drugs produced any side effects. Availability: Items available for loan: UVAS Library [Call number: 0770,T] (1).

21. Clinico Epidemiological Study Of Bacterial Causes Of Respiratory Syndrome In Cattle And Buffalo Around Lahore

by Ahtasham-ur-Rehman | Prof. Dr. Khalid Pervaiz | Dr. Muhammad Sarwar Khan | Prof. Dr | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Nature of contents: biography; Literary form: Publisher: 2009Dissertation note: The present study was undertaken to determine the bacterial agents associated with respiratory tract infections in cattle and buffalo. For this purpose 100 clinically sick cattle and 100 clinically sick buffalo of both sex and age were examined. The samples were taken randomly from the Outdoor Hospital of University of Veterinary and Animal Sciences. Lahore. various District Veterinary Hospitals of Lahore and Private Veterinary Clinics of Lahore during September 2004 to February 2005. All the animals presented during the above mentioned period were clinically examined. Those showing signs of cough and nasal discharge were clinically examined, and their respiration rate, pulse rate, temperature and lung auscultation was performed. The frequency of clinical signs were observed and found it as, abnormal lung sounds 36.5%, Nasal discharge 69%, Cough 73%, Anorexia 93.5%, Depression 90.5%, Dyspnea 28%, Fever 84.5%, Increased pulse rate 66%, Increased respiratory rate 76.5%, Increased breath sounds 64.5% and Loud breath sounds 56%.Whereas no above mentioned signs were observed in control group. A total of 200 samples of nasal mucus were collected from 100 clinically sick cattle and l00 clinically sick buffalo. Nasal swabs were collected from clinically sick animals. Nasal swabs collected from the nasal cavity of the affected animals, in gamma sterilized cultural swabs, were properly labeled and kept at 4°C till further processing. Each affected animal was also tested For Bovine Tuberculosis using Single Intradermal Test. Smears were made from each nasal swab, stained with Gram's staining and was examined for the presence or absence of bacteria. Each positive bacterial swab was inoculated in nutrient broth, tubes, which was incubated at 37°C and then examined after different intervals of time for turbidity. A loopful of material from positive turbid broth was streaked on the nutrient agar and incubated at 37°C for 24 hours. Different types of colonies were purified. Smears were prepared from each type of colony, stained with Gram's staining and examined under oil immersion lens. The staining and morphological characteristics were recorded. Out of total 200 samples, only 152 were positive for bacterial contamination. The prevalence so calculated was 76% amongst the animal examined. A total number of I 52 isolates belonging to the genera Pasteurella, Streptococcus. Staphylococcus. Escherichia and Mycobacteriurn were isolated and identified on the basis of morphological, staining, cultural and biochemical characters of the organisms isolated from nasal mucus of cattle and bLiffalo. Of these Pasteurella haemolytica was isolated from 43 (21 .5%), Pasteurella multocida 3 I (I 5.5%), Escherichia coli 11 (5.5%), Streptococcus 29 (14.5%), Staphylococcus 23 (11.5%) and Mycobacteriurn bovis 15 (7.5%). The main objective of this study was to assess and record the incidence of various bovine respiratory tract infections and to study the bacterial etiological agents involved in the production of respiratory tract syndrome. The etiological agents were identified by cultural and biochemical characteristics of isolates. These findings will help in devising proper and early measures required to cure the disease and to boost LI the prodLictive performance of these ruminants. Availability: Items available for loan: UVAS Library [Call number: 0870,T] (1).

22. Prevalence And Chemotherapy Of Helminthases In Parrots At Lahore Zoo.

by Ashgar Khan | Prof. Dr. Muhammad Sarwar Khan | Prof. Dr. Haji | Prof. Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2007Dissertation note: The study was conducted to determine the incidence of helminthiasis in all breeds of parrots and to evaluate the comparative efficacy of two different broad spectrum anthelmintics, albendazole (Farbenda, Farvet) and levamisole (Nilverm drench, ICI) used against the nematodes at Lahore Zoo. For this purpose, 130 Faecal samples were collected group wise in clean polythene bags, properly labeled for identification and examined for the identification of helminths. Eighty eight out of 130 were positive for single or mixed infection of Heterakis gallinae and Ascardia gaul have individual percentage as 73.86% and 26.14% respectively. Of 88 positive birds belonging to different breeds of parrots, 72 of the same age, weight and number were devided in three equal groups (24 each) i.e. A (love birds peach face breed), B (budgerigar ring necked breed), and C (Alexandrine parrots, Blossom headed parakeet and Blue fronted amazon breeds), while in group D (Cockatiel, Blue ring necked parakeet, Eclectus parrot and African grey parrot breeds), only uninfected and untreated birds were kept. Drug therapy was only induced to the group A i.e. albendazole (Farbenda, Farvet) @ 0.lml/kg body weight and group B (levemisole hcl (Nilverm, ICI) @ 5m1/litre of water, while infected but non treated birds were placed in group C. Faccal samples of experimental birds were examined for counting of egg/gram of faeces on day"O" (pre-medication) with McMaster egg counting technique (Soulsby, 1982). Faecal egg counts were again carried out on day 3, 7 and 10 of medication and percentage reduction of EPG calculated. The overall prevalence of gastro intestinal helminthes in different breeds of parrots was found as 67.69%. Albendazole was found to be the more effective (96.33%) among the two anthelmintics while levamisole was less effective (84.90%). The EPG rise up to 8.98% at day 10 post medication in untreated group C was noted while no infection was observed in group D through out the experimental study. Availability: Items available for loan: UVAS Library [Call number: 0962,T] (1).



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