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451. Effects Of Omega 3 And Vitamin E Against Experimentally Infected Low Pathogenic Avian Influenza Virus H9n2 In Broiler Chickens

by Muhammad Sulman Ali Taseer (2008-VA-089) | Prof. Dr. Asim Aslam | Prof. Dr. Zafar Iqbal Chaudhry | Prof. Dr. Kamran Ashraf.

Material type: book Book; Literary form: not fiction Publisher: 2015Dissertation note: Avian influenza is a highly contagious viral disease of domestic and wild birds. It is one of the most devastating viral disease of poultry industry. It was first identified in Italy in early 1900,s and is now known to exist worldwide. Total of 125 day old chickens were divided into five groups (A, B, C, D, E) with 25 chickens in each group. Group A was negative control group. In groups B, C, D and E low pathogenic avian influenza (H9N2) virus infection was introduced at day 28 of age. Group B was given with Omega 3. In group C chickens were given Vitamin. E. In group D chickens were fed both Omega 3 and Vitamin E. Group E was positive control group without any additional supplementation. At days 27, 30, 35, 42, blood was collected aseptically from wing vein, from three birds in each group to check H/L ratio and to perform HI test to check antibody titer for H9. After collection of blood five birds from each group were slaughtered to observe postmortem signs and for the histopathology of lungs and trachea. Heterophill to lymphocyte ratio was significantly high in groups D (Omega 3 and Vit.E) and group E (Positive Control). Among the various treatment groups of broilers the significantly highest HI antibody titer was recorded in group E which was positive control group. In treatment groups C (Vitamin E supplement) and D (Omega 3 and Vit.E) HI antibody titer was near to protective titer against H9. Major histopathological lesions involved deciliation of trachea and sloughing of epithelium of trachea. There was infiltration of monocytes and neutrophils as well as vascular congestion in the form of hemorrhagic areas in lungs. There was increase in congestion in the lungs of the chicks in group E (Positive Control). 37 FCR was evaluated on weekly basis. A comparatively better feed conversion ratio was recorded in group D (Omega 3 and Vit.E). There was no significant difference in feed conversion ratio of the other treatment groups. Availability: Items available for loan: UVAS Library [Call number: 2355-T] (1).

452. Laboratory Profiles of Small Animal Diseases : A Guide to Laboratory Diagnosis

by Sodikoff, Charles H.

Edition: 2nd ed.Material type: book Book; Format: print Publisher: USA: Mosby-Year Book; 1995Availability: Items available for loan: UVAS Library [Call number: 636.70896075 Sodikoff 15825 2nd 1995 Pathology] (1).

453. Cell Pathology / 1st ed

by Norman F. Cheville.

Edition: 1stMaterial type: book Book; Literary form: not fiction Publisher: USA: IOWA State University Press; 1976Availability: Items available for loan: UVAS Library [Call number: 636.08910181 Cheville 10971 1st 1976 Pathology] (1).

454. Food Animal Pathology and Meat Hygiene

by Herenda, Drago Carl | Franco, Don A.

Edition: 1stMaterial type: book Book; Format: print Publisher: USA: Mosby, 1991Availability: Items available for loan: UVAS Library [Call number: 636.089607 Herenda 14221 1st 1991 Pathology] (2).

455. Clinical Use of Blood Handbook

by World Health Organization.

Edition: 1st ed.Material type: book Book; Format: print Publisher: Geneva: World Health Organization; 2001Availability: Items available for loan: UVAS Library [Call number: 615.39 WHO 15330 1st 2001 Pathology] (1).

456. Color Atlas of Pathology

by U. S. Naval Medical School.

Material type: book Book; Format: print Publisher: USA: J. B. Lippincott, 1954Availability: Items available for loan: UVAS Library [Call number: 616 USNMC 10326 1st 1954 Pathology] (1).

457. Radiation Histopathology

by Casarett, George W.

Edition: 1st edMaterial type: book Book; Format: print Publisher: USA: CRC Press, 1980Availability: Items available for loan: Pattoki Library [Call number: 616.989707 Casarett 13436 Vol.1 1980 Histology] (1).

458. Diseases of the Liver

by Foulk, William T. M.D.

Edition: 1st ed.Material type: book Book; Format: print Publisher: USA: McGraw Hill; 1968Availability: Items available for loan: UVAS Library [Call number: 616.362 Foulk 10154 1st 1968 Pathology] (1).

459. Effect of Fish Oil on Response of Lymphoid Organs of Broiler Experimentally Infected With Newcastle Disease Virus

by Muhammad Zahid (2013-VA-441) | Dr. Muhammad Yasin Tipu | Dr. Muhammad Yasin Tipu | Prof. Dr. Asim Aslam | Prof. Dr. Khushi Muhammad.

Material type: book Book; Literary form: not fiction Publisher: 2015Dissertation note: Theses submitted with cd. Availability: Items available for loan: UVAS Library [Call number: 2353-T] (1).

460. Studies On The Effect Of Garvit-Pro® (A Commercial Product) On Broiler Chickens Vaccinated Against Infectious Bursal Disease

by Jawad Ahmad (2008-VA-109) | Prof. Dr. Asim Aslam | Dr. Muti Ur Rehman | Prof. Dr. Kamran Ashraf.

Material type: book Book; Literary form: not fiction Publisher: 2015Dissertation note: Infectious Bursal Disease (IBD) has become very notorious poultry disease in Pakistan. The disease affects the primary lymphoid organs (bursa of Fabricius) of the poultry and cause mild to severe immune suppression in affected birds. In accordance of the mentioned fact, present experimental project was designed to evaluate the effects of immune boosters after IBD vaccination and compare the effects of GarVit-Pro with only vaccinated birds. Humoral immune response against IBD virus was measure through Enzyme Linked Immunosorbent Assay (ELISA). There were total 90 bird, divided into 3 groups with 30 birds in each group. The blood sample were collected from different experimental groups of broiler chickens on 07, 14, 21, 28 & 35 days of age. Among the various experimental groups of broiler chickens the significantly highest antibody titer was recorded in group B fed with GarVit-Pro (Garlic Supplement) as compared to the other vaccinated and unvaccinated groups. The histopathological scoring of Bursa of Fabricius and thymus in different experimental groups was observed at day 07, 14, 21, 28 and 35. The bursal lesion scores of Group B (GarVit-Pro Treated) was lower than the other two groups. The GarVit-Pro helped to enhance the antibody titer against IBD virus after vaccination. These findings suggest and advocates that GarVit-Pro (garlic supplement) can effectively stimulate and enhance the immunity in broiler chickens. GarVit-Pro can be potential ameliorator against different vaccines and their unwanted/suppressive effects in broiler chicks. It was proved that GarVit-Pro is able to implement immune response and have a patent immunomodulatory effect in chickens Availability: Items available for loan: UVAS Library [Call number: 2363-T] (1).

461. Pathophysiology of Parasitic Infection

by Soulsby, E.J.L.

Edition: 1stMaterial type: book Book; Format: print Publisher: USA: Academic Press Inc, 1976Availability: Items available for loan: UVAS Library [Call number: 636.089696 Soulsby 11834 1st 1976 Parasitology] (1).

462. Pathology of Tumours in Laboratory Animals / Vol.3

by Turusov.

Material type: book Book; Format: print Publisher: Switzerland: International Agency for Research on Cancer, 1982Availability: Items available for loan: UVAS Library [Call number: 599.323 IARC 12855 Vol.3 1982 Pathology] (1).

463. Hematological And Histopathological Study Of Paramphistomum Cervi In Large Ruminants

by Abdul Majeed Saim (2012-va-814) | Prof. Dr. Asim Aslam | Mr. M. Saeed Imran | Prof. Dr. Kamran Ashraf .

Material type: book Book; Literary form: not fiction Publisher: 2015Dissertation note: Paramphistomes are the parasites in the rumen, reticulum, duodenum and liver of goats, sheep, cattle and buffaloes. Their premature stages are in duodenum and then traveled towards the rumen. The damage caused by this illness in bovine affects production. These parasites aggravate a loss of weight, a lower nutritious conversion and a reduce in milk production. Lahore is one of the larger district in the Punjab province of Pakistan. The present study was conducted in order to implement efforts and regulation to eradicate the spread of disease in this area. From this study it was evaluated the changes in hematological parameters values of Large Ruminants and evaluated the Histopathological changes in rumen, reticulum, duodenum and liver. Samples of blood and tissues were collected at slaughter house from cattle and buffaloes after slaughtering. These were divided into three groups i.e group-A (Infected Buffaloes=50), group-B (Infected Cattle=50) and group-C (Buffaloes, Cattle=20) serve as control. The blood samples and tissue samples of rumen, reticulum, duodenum and liver were taken from infected cattle and buffalo tested positive by fecal examination through direct smear technique and was processed for hematological and histopathological examination. The infected cattle and buffaloes in this study described a highly significant decrease (p<0.05) in the mean red blood cells, packed cell volume, total erythrocyte count and hemoglobin. There was a significant increase (p<0.05) in the neutrophils number and eosinophil number of disease buffaloes and cows as compared to the non-infected buffaloes and cows. The infection of paramphistomum cervi is characterized by severe anemia, eosinophilia, neutrophilia. Anemia can be responsible for mortality in cattle and buffaloes especially young ones. Pathological changes were observed grossly and confirmed histopathologically in the rumen, reticulum, duodenum and liver. Pathological changes were mostly limited to small intestine, especially duodenum. The disease caused by the parasite in the rumen was increased cornification of the stratum corneum, atrophy, severe infiltration and thickening of mucosa occurs in the rumen papillae, but no ulceration was found. Changes varied from a localized enteritis and villous atrophy in the duodenum in light disease to severe destructions of the mucosa extending into most of the jejunum in heavy infections. Mucosa at places was found congested with petechial haemorrhages. The histopathological analysis of the diseased liver of buffalos and cows has described that severe harm has occurred in this infection. In most of the sections, the normal structure of liver tissue, arrangement of hepatocyte cords, veins and portal tube areas were undergone clear with full bile ducts indicating bile duct hyperplasia, necrosis of liver tissue and cause necrosis. The immature forms of Paramphistomium cervi caused more severe damage in the duodenal tissue, where as adult forms inflicted mild tissue damage in the rumen. The present study was conducted in order to implement efforts and regulation to eradicate the spread of disease in this area. From this study it was evaluated the changes in hematological parameters values of Large Ruminants and evaluated the Histopathological changes in rumen, reticulum, duodenum and liver. Availability: Items available for loan: UVAS Library [Call number: 2368-T] (1).

464. Effects Of Fish Oil On The Histopathology Of Lymphoid Organs Of Broiler Experimentally Infected With Infectious Bursal Disease Virus

by Safdar Fareed Rabbani (2012-va-637) | Prof.Dr.Asim Aslam | Dr.Muti-Ur-Rehman | Prof.Dr.Kamran Ashraf.

Material type: book Book; Literary form: not fiction Publisher: 2015Dissertation note: Infectious Bursal Disease has become the major poultry disease in Pakistan. The disease causes immune suppression due to damage to primary lymphoid organs (Bursa of Fabricius) in affected birds. Supplementation of fish oil enhances the immune status and subside the inflammatory conditions. So this study was designed to study the effects of fish oil on histopathology of lymphoid organs and growth performance of broiler birds. For this purpose a total number of 80 day old Hubbard broiler chicks were randomly divided into four group i.e. A, B, C and D. Group A and B were challenged with IBD Virus with known (EID50 106/ml) dose was 0.1 ml intranasal on 21th day of age, Group B and C were treated with 3% fish oil while group D acted as a negative control. Blood was collected from birds on irregular interval of days 20, 22, 29, 36 and 42 for monitoring of antibody titer against IBD virus and ND vaccine. For the histopathology the lymphoid organ were collected on day 20, 22, 29, 36 and 42. Feed consumption of group A and D during 1st week of age was significantly higher than group B and C. The broilers of group A consumed feed without fish oil significantly higher than broiler of group D while, the broilers of group C consumed feed containing fish oil significantly higher from the broilers of group D after challenged with IBD. The body weight of birds of group B and C supplemented with fish oil mixed feed was significantly (p<0.05) higher than broilers receiving feed without fish oil before challenged, however after challenge the body weight gain of group C was significantly higher than group B while that of group D was significantly (p<0.05) higher group A. The feed conversion ratio (FCR) of birds supplemented with fish oil was significantly different from the broilers receiving feed without fish oil before challenged. Summary 48 However after challenged significant difference was observed with highest value of FCR by group C, followed by group B, group A and group D. Before challenged, group C show the highest Mean titer value (606.0) for IBDV followed by group B (466.0), C (288.0) and D (106.5), However, after challenge the highest value of Mean titer for IBDV was observed in group B with 5006.0, followed by group C, A and D with Mean titer of 4608.0, 4469.0, and 4015.0, respectively on 42nd day of age. During Histopathological examination, congestion, depletion of lymphocytes, dysplasia of thymic lobules, thinning of cortex, focal necrosis, disappearance of lymph follicles and interfollicular edema like lesions were observed in the lymphoid organs of challenged birds. However, cellular hypertrophy, increased lymphocytes population and presence of lymphoblast were the prominent changes in lymphoid organs of broilers supplemented with 3% fish oil, while no pathological lesions were notified in the lymphoid organs of control group. From this study, it was concluded that Infectious Bursal Disease causes immune suppression and damage immune organs in broiler, with an associated loss of response to Newcastle disease vaccine. It was also concluded from the current study that, fish oil had beneficial effect on the antibody titer against Infectious Bursal disease virus and on growth performance in broilers. The fish oil also showed therapeutic effect against Infectious Bursal Disease. Availability: Items available for loan: UVAS Library [Call number: 2364-T] (1).

465. Distribution and Localization of Brucella Melitensis in Aborted Fetal Tissues of Small Ruminants

by Muhammad Zain Saleem (2008-va-158) | Dr. Raheela Akhtar | Prof. Dr. Asim Aslam | Dr. Haroon Akbar.

Material type: book Book; Literary form: not fiction Publisher: 2015Dissertation note: Submitted with blank CD. Availability: Items available for loan: UVAS Library [Call number: 2369-T] (1).

466. Diseases of the Goat / 2nd ed.

by Matthews, John G.

Edition: 2nd ed.Material type: book Book; Format: print Publisher: UK: Wiley-Blackwell, 1999Availability: Items available for loan: UVAS Library [Call number: 636.390896 Matthews 17969 2nd 1999 Sheep&Goat] (1).

467. Diseases of the Goat / 2nd ed.

by Matthews, John G.

Edition: 2nd ed.Material type: book Book; Format: print Publisher: UK: Wiley-Blackwell, 1999Availability: Items available for loan: UVAS Library [Call number: 636.390896 Matthews 15040 2nd 1999 Sheep&Goat] (1).

468. Pathology of Laboratory Rodents and Rabbits

by Percy, Dean H | Barthold, Stephen W.

Edition: 1st ed.Material type: book Book; Format: print Publisher: USA : Iowa State Press, 1993Availability: Items available for loan: UVAS Library [Call number: 636.932 Percy 13573 1st 1993 Pathology] (1).

469. Laboratory Profiles of Equine Diseases

by Eades, Susan C | Denise I. Bounous DVM.

Edition: 1st ed.Material type: book Book; Format: print Publisher: USA: Mosby, 1997Availability: Items available for loan: UVAS Library [Call number: 636.108960756 Eades 18251 1st 1997 Horse] (3).

470. Handbook on Tropical Diseases

by The British Veterinary Association.

Edition: 1st ed.Material type: book Book; Format: print Publisher: UK : The British Vet Association, 1962Availability: Items available for loan: UVAS Library [Call number: 619.0913 BVA 11546 1st 1962 CMS] (1).

471. Manual of veterinary investigation laboratory techniques :Vol.1

by Ministry of Agriculture, Fish.& Food.

Edition: 3rd ed.Material type: book Book; Format: print Publisher: UK : Stationery Office Books, 1984Availability: Items available for loan: UVAS Library [Call number: 636.089028 MAFF 12721 3rd 1984 Pathology] (1).

472. Pathological Investigation Of Hydatid Cyst In Sheep And Goats At Lahore Abattoirs

by Syed Shan Raza (2013-VA-444) | M. Saeed Imran | Dr. Raheela Akhtar | Dr. Nisar Ahmad.

Material type: book Book; Literary form: not fiction Publisher: 2015Dissertation note: Hydatidosis is an important zoonotic disease caused by E.granulosus. The parasite causes production loss in meat industry by damaging lungs and liver of food producing animals which leads to decrease in body weight of animals. Animals suffering from Hydatidosis also slaughtered in abattoirs for meat production. These animals should be treated and proper control strategies should be adopted by deworming to control the production loss in meat industry. Histopathological findings are important to understand the reason for rejection of carcass along with viscera. The present study was designed to investigate the biochemical findings of hydatid cyst from lungs and liver of sheep and goats which can provide valuable information for determining the strains of E. granulossus, and to check current status of the disease at Lahore abattoirs, so that proper control strategies should be adopted to control this zoonotic disease. A total of 1600 animals comprising 796 sheep and 804 goats of both sexes were examined for hydatid cyst in the month of August to November 2015 for determining the prevalence of E.granulosus in the particular time period. Total of 60 cysts samples from lung and liver of the sheep and goats were collected in the buffered formalin to check the biochemical profile for strain differentiation (30 from liver and lungs of sheep and 30 samples from liver and lungs of Goats). All the samples were collected form Lahore meat processing complex. The tissue samples of lungs and liver were subjected to histopathology. Histopathology was performed for lesion identification in tissues infected with hydrated cyst in the presence of viable and inviable cyst. Summary 38 In present study, overall prevalence of hydatidosis in sheep was found as 7.91 %. In lambs, the prevalence was almost similar in males 1.23 % and females 1.44 % but in adults, it was significantly higher 10.74 % in females as compared with males 6.46%. The prevalence was significantly higher 7.91 % in adults than in hoggets 1.32 %. In goats the overall prevalence of hydatidosis was found as 5.60%, prevalence was much higher in adult males 4.38 % than in young ones 0.64 %. Similarly there was a significant difference in the prevalence between young 1.36 % and adult females 7.88 %. In the present study, overall prevalence in goats was recorded as 5.60 % which is significantly lower than the found in sheep 7.91 %. The prevalence was significantly higher in adult male sheep than that in adult male goats. It was observed that cysts removed from liver in both the species were more fertile than those of collected from lungs and also reported that hepatic cyst are more fertile than the cysts found in lungs. The biochemical comparison helped in the characterization and identification of strains of E.granulosus at Lahore region. The obtained data was statically observed on student t test for the detection of mean difference in the biochemical profile of the both sheep and goat cysts. Statically there was significant difference found in the total Glucose, triglycerides, and cholesterol, levels in hydatid cyst fluid obtained from the sheep and goats. These difference was due to the strain variation of E.granulosus. There was no significant difference in the biochemical levels of urea, uric acid, total protein, creatinine, calcium and phosphorous. The level of glucose and triglycerides in sheep was 6.3 and 0.63 mmol/lit respectively which was significantly higher than hydatid cyst fluid of goats i.e., 4.2 and 0.39 mmol/lit respectively. The level of the cholesterol in sheep was lower than that of goats which was 0.14 and 0.39 mmol/lit respectively. Study helped us to know the current status of Hydatidosis in small ruminants at Lahore which causes production loss in meat industry. The biochemical examination of cystic fluid helped us to know about the probability of the status of strains of E.granulosus present. Current biochemical profile indicates probability of two strains of E.granulosus are prevalent at Lahore for strains characterization and identification further studies are needed. The histopathological study helped us to find out the pathological changes at the tissue level in the presence of cyst in the tissues of the lungs and liver of sheep and goats. Availability: Items available for loan: UVAS Library [Call number: 2386-T] (1).

473. Year Book of Pathology and Clinical Pathology

by Carone, Frank A.

Material type: book Book; Format: print Publisher: USA: Year Bk. Med. Pub., Availability: Items available for loan: UVAS Library [Call number: 616.07 Carone 10975 1st 1979 Pathology] (1).

474. Manual of Diagnostic Tests and Vaccines for Terrestrial Animals : Mammals, Birds and Bees / Vol.2

by Office international des epizooties.

Edition: 5thMaterial type: book Book; Literary form: not fiction Publisher: Paris : OIE; 2004Availability: Items available for loan: UVAS Library [Call number: 636.089 WOAH 19003 5th 2004 Pathology] (2).

475. Manual of Diagnostic Tests and Vaccines for Terrestrial Animals : Mammals, Birds and Bees / Vol.1

by Office international des epizooties.

Edition: 5thMaterial type: book Book; Literary form: not fiction Publisher: Paris : OIE; 2004Availability: Items available for loan: UVAS Library [Call number: 636.089 WOAH 19002 5th 2004 Pathology] (2).

476. Fish Pathology / 3rd ed.

by Robberts, Ronald.

Edition: 3rd ed.Material type: book Book; Literary form: not fiction Publisher: China: W.B Saunders; 2001Availability: Items available for loan: Pattoki Library [Call number: 597 Robberts 16276 3rd 2001 Fisheries] (1).

477. Veterinary Pathology / 4th ed

by Smith, Hilton Atmore | Jones, Thomas Carlyle | Hunt, Ronald Duncan.

Edition: 4th ed.Material type: book Book; Format: print ; Literary form: not fiction Publisher: Philadelphia: Lea & Febiger; 1972Availability: Items available for loan: UVAS Library [Call number: 636.089 Hilton 11362 4th 1972 Pathology] (1).

478. Veterinary Clinical Pathology

by Sastry, A. Ganti.

Edition: 1st ed.Material type: book Book; Literary form: not fiction Publisher: India: CBS Publishers; 1989Availability: Items available for loan: UVAS Library [Call number: 636.089607 Sastry 29578 3rd 1989 Pathology] (2).

479. pH & Dissociation : A Learning Program for Students of the Biological and Medical Students

by Christensen, Halvor. N.

Edition: 2ndMaterial type: book Book; Literary form: not fiction Publisher: LONDON; W.B.SAUNDERS: 1963Availability: Items available for loan: UVAS Library [Call number: 533.3 Halvor 9041 2nd 1964 Pathology] (1).

480. Atlas of Clinical Radiology of Farm Animals/1st ed.

by Nigam,J.M.

Edition: 1st ed.Material type: book Book; Literary form: not fiction Publisher: India: Allied Publishers, 1985Availability: Items available for loan: Pattoki Library [Call number: `636.0890757 Nigam 13002 1st 1985 Pathology] (1).

481. Handbook on Laboratory Animals / 2nd ed.

by Desai, PV.

Edition: 2nd ed.Material type: book Book; Literary form: not fiction Publisher: India: Jaypee Brothers; 2015Availability: Items available for loan: UVAS Library [Call number: 616.07 Desai 30876 2nd 2015 Pathology] (1).

482. Laboratory Procedures for Veterinary Technicians / 6th ed.

by Sirois, Margi.

Edition: 6th ed.Material type: book Book; Literary form: not fiction Publisher: China: Elsevier; 2015Availability: Items available for loan: Pattoki Library [Call number: 636.08960756 Sirois 50503 6th 2015Pathology] (2), UVAS Library [Call number: 636.08960756 Sirois 31868 6th 2015 Pathology] (2).

483. Atlas of Forensic Pathology

by Shetty, Suresh Kumar | Rstogi, Prateek | Padubidri, Jagadish Rao | Babu, YP Raghavendra.

Edition: 1st ed.Material type: book Book; Literary form: not fiction Publisher: New Delhi: Jaypee Brothers Medical Publishers; 2014Availability: Items available for loan: UVAS Library [Call number: 614.1 Shetty 30932 1st 2014 Forensic] (1).

484. Death Scene Investigation: Procedural Guide

by Maloney, Michael S.

Edition: 1st ed.Material type: book Book; Literary form: not fiction Publisher: USA: CRC Press; 2012Availability: Items available for loan: UVAS Library [Call number: 614.1 Maloney 30929 1st 2012 Forensic] (1).

485. Sodeman's Pathologic Physiology : Mechanisms of Disease

by Sodeman, William A. (ed) | Sodeman, Thomas M. (ed).

Edition: 6th ed.Material type: book Book; Literary form: not fiction Publisher: Philadlphia: W.B. Saunders Co.; 1979Availability: Items available for loan: UVAS Library [Call number: 616.07 Sodeman 18575 6th 1979 Pathology] (1).

486. Death and Accident Investigation Protocols

by Dudley, Mary H.

Edition: 1st ed.Material type: book Book; Literary form: not fiction Publisher: USA: CRC Press; 2013Availability: Items available for loan: UVAS Library [Call number: 614.1 Dudley 30928 1st 2013 Forensic] (1).

487. Color Atlas of Immunology/ist ed.

by Burmester,G.R.

Edition: 1st ed.Material type: book Book; Literary form: not fiction Publisher: China: Thieme, 2006Availability: Items available for loan: Pattoki Library [Call number: 616.079 Burmester 19390 1st 2006 Pathology] (1).

488. Jubb, Kennedy and Palmer's Pathology of Domestic Animals / Vol.1

by Maxie, M. Grant | Jubb, K. V. F.

Edition: 5th edMaterial type: book Book; Literary form: not fiction Publisher: New York : Elsevier Saunders, 2007Availability: Items available for loan: UVAS Library [Call number: 636.089607 Maxie 22846 5th.Vol.1 2007 Pathology] (1).

489. Jubb, Kennedy and Palmer's Pathology of Domestic Animals / Vol.2

by Maxie, M. Grant | Jubb, K. V. F.

Edition: 5th edMaterial type: book Book; Literary form: not fiction Publisher: New York : Elsevier Saunders, 2007Availability: Items available for loan: UVAS Library [Call number: 636.089607 Maxie 22847 5th.Vol.2 2007 Pathology] (1).

490. Jubb, Kennedy and Palmer's Pathology of Domestic Animals / Vol.3

by Maxie, M. Grant | Jubb, K. V. F.

Edition: 5th edMaterial type: book Book; Literary form: not fiction Publisher: New York : Elsevier Saunders, 2007Availability: Items available for loan: UVAS Library [Call number: 636.089607 Maxie 22848 5th.Vol.3 2007 Pathology] (1).

491. Fundamentals of Veterinary Clinical Pathology / 2nd ed

by Stockham, Steven L | Scott, Michael A.

Edition: 2nd ed.Material type: book Book; Literary form: not fiction Publisher: Ames, Iowa : Blackwell Pub., 2008Availability: Items available for loan: UVAS Library [Call number: 636.089607 Stockham 16509 1st 2002 Pathology] (2).

492. Veterinary Clinical Pathology : A Case Based Approach

by Freeman, P. Kathleen.

Edition: 1stMaterial type: book Book; Literary form: not fiction Publisher: India: CRC Press; 2015Availability: Items available for loan: UVAS Library [Call number: 636.089607 Freeman 32251 1st 2015 Pathology] (2).

493. Pathological Investigations Of Liver Of Nili-Ravi Buffaloes In Lahore District

by Hassan Masood (2012-VA-993) | Dr. Muhammad Saeed Imran | Dr. Irfan Irshad | Dr. Nisar Ahmad.

Material type: book Book; Literary form: not fiction Publisher: 2015Dissertation note: Livestock in Pakistan is an integral part for all systems of farming and is considered as cash income on daily basis for small holders. From economy point of view, buffalo has much importance and used for draught, meat and milk purposes. Out of the total animal’s population, up to 47 percent dairy population comprises on Buffaloes. Globally minute study has been documented on pathological investigations of liver in Buffaloes and very rare is documented in Pakistan. The present study was designed to investigate histopathological liver lesions in Buffaloes at Shahpur Kanjra slaughter house located in District Lahore. A total of 100 diseased liver samples of Buffaloes were brought to the department of Pathology, University of Veterinary and Animal Sciences (UVAS), Lahore. These samples were examined for gross pathological lesions such as presence of abscess, hemorrhages and Hydatid cysts along with thickness, color and texture. For histopathological studies we persevered these samples in 10% neutral buffered formalin solution. Paraffin embedding technique was used to process the samples which were stained by Haematoxylin and Eosin method. The results of our study revealed percentages of different diseased conditions in the Liver tissues of slaughtered buffaloes. The percentage of Hydatidosis was found high among all the conditions and reported as 28 percent. The conditions of the Amphistomiasis were reported as 22 percent. While Cirrhosis disease was prevalent in the buffaloes at the rate of 18 percent. The percentage after the cirrhosis was found for the condition of Granulomatous hepatitis which was Summary 37 16 percent. The percentages of Abscess, Fascioliasis and Haemorrhages were found as 7, 6 and 3 percent respectively. In conclusion, theses above mentioned pathological conditions reported in our study served as major cause of liver condemnation at Shahpur Kanjra slaughter house of Lahore District, which may also contributed the economic losses. To mitigate the economic and public health impacts proper deworming plan along with good animal husbandry practices would probably be effective in decreasing incidence of these Liver diseases. Availability: Items available for loan: UVAS Library [Call number: 2435-T] (1).

494. Pathological Investigations Of Different Isolates Of H9n2 Prevalent In Broiler Chicken

by M. Furqan Shahid (2014-VA-322) | Dr. Yasin Tipu | Prof. Dr. Asim Aslam | Prof. Dr. Tahir Yaqub.

Material type: book Book; Literary form: not fiction Publisher: 2016Dissertation note: In recent years, H9N2 virus has attained a great importance as its infection has reached panzootic proportions. AIV H9 has different antigenic variants that has made it problematic to diagnose and thus to understand the pathogenicity of this virus is also very difficult. Detection of AI H9 antibodies can be used as a complementary method for sero-epidemiological studies as an indicator of AI H9 infection. The haemagglutination inhibition (HI) assay is used routinely for subtyping and detecting an increase of antibodies to AI viruses. Surveillance and early diagnosis of AI virus is essential for poultry. It demands rapid, sensitive and inexpensive diagnostic tests. Thus, it is important to identify different antigenic variants of H9. In this study a total of seven H9 virus samples were isolated out of total 100 collected sample from field outbreaks. These isolates were confirmed by molecular methods like PCR. Then four isolates from these seven isolates were used to infect the experimental broiler chicken. Clinical signs were recorded after the inoculation of H9N2 virus to the broiler. The results of this study showed that clinical signs were more sever upto 5 DPI. The severity of signs was proved by observing the gross pathology and histopathology of organs (Lung, Kidney, Trachea and Liver) of infected birds which were collected on 5 and 9 DPI. Serum of infected birds was also collected on 7 and 14 DPI to analyze the antibody level of infected birds against experimentally used isolate of H9N2. Then cross reactivity of different isolates of H9N2 was also checked against pannel of hyperimmune sera raised against different isolates of H9N2 and their results showed different antibody level against different isolates of H9N2. The sero-biochemical study of serum of infected birds revealed that H9N2 virus has pathogenic potential on kidney and liver. Availability: Items available for loan: UVAS Library [Call number: 2459-T] (1).

495. Studies on Pathogenesis and Molecular Diagnosis of Infectious Bursal Disease Virus In Broiler Chicken

by Beenish Zahid (2003-VA-134) | Prof. Dr. Asim Aslam | Dr. Yasin Tipu | Prof. Dr. Tahir Yaqub.

Material type: book Book; Literary form: not fiction Publisher: 2015Dissertation note: Blank CD. Availability: Items available for loan: UVAS Library [Call number: 2510-T] (1).

496. Amelioration Of Pathological Effects Of New Castle Disease By Aloe Vera

by Sayyed Raza Ali Shahid (2014-VA-515) | Prof. Dr. Zafar Iqbal Chaudhry | Dr. Gulbeena Saleem | Prof. Dr. Aftab Ahmed Anjum.

Material type: book Book; Literary form: not fiction Publisher: 2016Dissertation note: Poultry industry has many threats from the infectious diseases. Newcastle disease is the most important disease of the poultry as it is distributed all over the world and it can cause huge economic losses in poultry industry. It is caused by the Newcastle disease virus (NDV) that can infect about 240 species of birds. Newcastle disease cause immune suppression in birds. It is reported that supplementations of Aloe vera enhances the immune status and reduce inflammation. So this research project was design to observe the effect of Aloe vera on lymphoid organs, growth performance and antibody response in Newcastle disease challenge birds. For this research a total of 120 broiler chicks were divided into four groups A, B, C, and D. Group A was control group while B and C were treated with 2 percent aqueous extract of Aloe vera. Group C was also vaccinated against New Castle disease. Aloe vera was given to group B and C from day one to end of study trial. Both of the groups were challenged with ND virus at day 21. Group D was vaccinated against ND and was challenged with ND virus at day 21 without supplementation of Aloe vera. Blood samples were collected at day 1, 7, 20, 24, 26 and 28 to determine the antibody titer against ND. Highest antibody titers were observed in group C as compared to all other groups which was vaccinated against ND along with supplemented with Aloe vera. For gross pathology and histopathology, lymphoid organs were collected at day 24, 26 and 28..The average feed intake of group A and D was significantly higher than group B and C before challenge of virus but the body weight gain of 2% Aloe vera supplemented broiler was significantly (p<.05) higher than without treatment of Aloe vera. The FCR of birds supplemented with Aloe vera treatment was significantly different from the birds without Aloe vera treatment. The FCR value of group C and B was higher than A and D. lxxv A significant difference was observed in the weight of lymphoid organs of birds treated with Aloe vera as weight of organs was less in group C followed by group B, group A and group D. This was due to anti-inflammatory effects of Aloe vera. Microscopic examination revealed congestion, depletion of lymphocytes, dysplasia of thymic lobules, thinning of cortex, focal necrosis, disappearance of lymph follicles and inter-follicular edema like lesions within lymphoid organ of the groups challenged with Newcastle disease virus. However, cellular hypertrophy and decreased lymphocytes population were prominent changes in lymphoid organs of broiler treated with 2% Aloe vera. To check the virucidal effects of Aloe vera, a separate experiment was conducted in which 9 day old embryonated eggs were inoculated with ND virus along with 2 percent Aloe vera gel extract after incubation at 37Cº for an hour in group A while only ND virus was inoculated in group B. Candling was performed to see the survival of embryos in both groups which revealed a significant difference i.e. 16 percent embryos were found dead in group A while 80 percent was found dead in group B. Later on the amnioallantoic fluid of the eggs was used for spot Haemagglutination test. Group A showed less agglutination activity then group B. From this study it was concluded that Newcastle disease caused immune suppression and damage of vital organs in broiler while Aloe vera have immunomodulatory, anti-inflammatory and antiviral effects as it raised antibody titer against Newcastle disease virus and lowered the inflammatory processes along with inactivation of ND virus. It also promotes growth performance of broilers and helps the birds to survive against lethal ND disease. Availability: Items available for loan: UVAS Library [Call number: 2525-T] (1).

497. Immuno-Modulatory Effects Of Beta-Glucans And Nucleotides Based Commercial Products In Broiler Chicken Experimentally Infected With Velogenic Newcastle Disease Virus

by Hafiza Zain ul Fatima (2008-VA-232) | Prof. Dr. Asim Aslam | Dr. Raheela Akhter | Dr. Aamir Ghafoor.

Material type: book Book; Literary form: not fiction Publisher: 2016Dissertation note: Immune-potentiation effect of commercially available products containing beta-glucans (betaplex and catalyzer) and nucleotides (electroimmune and avimmune) in the broilers was evaluated. A total of 120 broiler chicks were reared under standard husbandry conditions. The birds were vaccinated by live NDV vaccine at 5, 14 days and killed Newcastle disease virus (NDV) vaccine at 7 days of age. Additionally, live infectious bronchitis and infectious bursal disease vaccines were also given through water at 5 and 10 days of age, respectively. The birds were randomly divided into six groups each comprising 20 birds. Four groups (treatment groups) were offered four commercial immune-booster products at 7, 14 and 21 days of age for 72 hours. Fifth group (untreated vaccinated) was not offered any drug while sixth group (untreated and unvaccinated) was not given any drug and also remained unvaccinated against NDV. Anti NDV antibodies were measured at 7, 14, 21 and 28 days of age and heterophil/lymphocyte (H/L) ratio was measured at 14, 21 and 28 days. Weight of immune organs and performance of birds was also measured from each group. Finally, 15 birds from each group were inoculated with virulent NDV through intranasal route at 28 days of age to assess the protection against challenge infection. Mean GMT anti NDV antibody titers in vaccinated groups were 3.65 (±0.59) at one week of age which were raised to the levels of 5.85 (±0.88), 5.50 (±1.00), 6.10 (±0.64), 5.90 (±0.91) and 5.45 (±1.05) in the betaplex, catalyzer, electroimmune, avimmune, and untreated control groups, respectively. Maximum antibody titer was achieved in electroimmune treated group while minimum in the catalyser treated ones. In non-vaccinated control group the antibody titers were minimum in the beginning that reduced to negligible level at four weeks of age. The H:L ratio of Summary 48 all treatment groups did not significantly vary at 14 days of age while at 21 and 28 days of age, the birds receiving electroimmune have significantly low H:L ratio in comparison to other treatment groups. Weight of liver and spleen in nucleotide treated groups was significantly higher than other treatment and control groups while there was no significant difference in the weight of bursa of fabricious in all treatment groups. Relative weight of all immune organs to the live body weight did not significantly vary in all treatment and control groups. Performance of the birds as a measure of feed conversion ratio (FCR) was highest in electroimmune treated birds. The challenge protection data shows that minimum mortality of 40 % (6/15) was observed in nucleotides treated groups while betaplex and catalyzer treatment groups have 47 % (7/15) and 53 % (8/15) mortality ratios in comparison to 60 % (9/15) mortality in untreated birds. Results of present study suggest that nucleotide or beta glucans supplementation in the diet have beneficial effects to enhance the humoral immune response and better bird performance in broilers. Use of these products not on delay the onset of clinical disease but also helpful in providing better protection against challenge to velogenic NDV. Availability: Items available for loan: UVAS Library [Call number: 2516-T] (1).

498. Pathogenesis Of Field Isolates Of Mannheimia Hemolytica In Experimentally Infected Rabbits

by Syeda Fakhra Waheed (2014-VA-10) | Prof. Dr. Zafar Iqbal Chaudhry | Prof. Dr. Asim Aslam | Prof. Dr. Aftab Ahmed Anjum.

Material type: book Book; Literary form: not fiction Publisher: 2016Dissertation note: Shipping fever is one of the most economically important infectious diseases of ruminants with a wide prevalence throughout the continents. The disease is characterized by an acute febrile course with severe fibrinous bronchopneumonia. Infected animals may die within a few days of the onset of clinical signs, but those which survive the acute attack may become chronically infected. Both Mannheimia and Pasteurella species are commensally resident in the respiratory tract of healthy ruminants and are capable of causing infection in animals with compromised pulmonary defense system. Bovine respiratory disease (BRD) is the most common and costly problem encountered in stocker or feedlot calves. BRD also called “shipping fever”, accounts for major economic losses to the producer by reducing average daily gain, feed efficiency, and overall performance of beef calves. The aim of present study was isolation of M.haemolytica from cattle. The identification of organism was performed through biochemical tests and confirmation by polymerase chain reaction. The nature of disease was evaluated through gross and microscopic lesions. A total of 50 tissue samples (25 lungs and 25 pharynx) were collected from Punjab Agriculture and Meat company Lahore and brought to the Department of Pathology UVAS, Lahore and were analyzed for biochemical and molecular detection of M .haemolytica. For studying the pathogenesis of the disease, experimental infection was given to rabbits in Department of Pathology, UVAS Lahore. Rabbits were randomly divided into Group A, Group B and Group C with nine rabbits (n=9) in each group. Experimental infection of field isolated M. hemolytica was given intratrachealy to the rabbits. Rabbits of group A and B were infected with 0.5 mL bacterial inoculum having 103 and 106 CFU/mL respectively. The rabbits of Group C served as control group. Rectal temperature of each rabbit was recorded daily. On postmortem, CHAPTER 6 SUMMARY Summary 67 gross and microscopic lesions were recorded. The results showed that rabbits of control group not showed any gross or microscopic change. There was significant increase in rectal temperature of infected rabbits as compared to uninfected rabbits. The gross lesions were specific for the organism which was prominently observed in lungs of rabbits. The microscopic lesions revealed that there was severe consolidation, congestion and fibrin exudation in lungs of rabbits of group A which were given less number of organism and they developed clear signs of disease. The rabbits of Group B showed less prominent signs compared to group A due to early death of rabbits. There were multiple hemorrhages, of varying sizes and hyalinization of myocardial cells in infected rabbits. The severity of changes was significantly more different in Group A, as compared to Group B. It can be deduced by this study that the rabbit can be used as a model for further studies exploring the pathogenesis of the disease as the lesions resemble to shipping fever caused by M. hemolytica in ruminants. The lesions, which developed, could be descending infection resulting in typical lesions of bronchopneumonia or lobular pneumonia. Availability: Items available for loan: UVAS Library [Call number: 2517-T] (1).

499. Diagnostic Techniques in A.R

Material type: book Book; Format: print ; Literary form: not fiction Availability: No items available Checked out (1).

500. Laboratory Manual of Mamalian

Material type: book Book; Format: print ; Literary form: not fiction Availability: No items available Checked out (1).



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