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Engineering the Genetic Code : Expanding the Amino Acid Repertoire for the Design of Novel Proteins

By: Budisa, Nediljko.
Material type: materialTypeLabelBookPublisher: Germany : Wiley-VCH, 2006Edition: 1st ed.Description: 312 p.ISBN: 3527312439 (hardcover); 9783527312436 (hardcover).Subject(s): Protein engineering | Amino acids--Synthesis | Proteins--Biotechnology | Amino acids | GeneticsDDC classification: 660.65 Budisa 19433 1st 2006 Genetics Summary: The ability to introduce non-canonical amino acids in vivo has greatly expanded the repertoire of accessible proteins for basic research and biotechnological application. Here, the different methods and strategies to incorporate new or modified amino acids are explained in detail, including a lot of practical advice for first-time users of this powerful technique. Novel applications in protein biochemistry, genomics, biotechnology and biomedicine made possible by the expansion of the genetic code are discussed and numerous examples are given. Essential reading for all molecular life scientists who want to stay ahead in their research.
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Veterinary Science 660.65 Budisa 19433 1st 2006 Genetics (Browse shelf) Available 19433
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The ability to introduce non-canonical amino acids in vivo has greatly expanded the repertoire of accessible proteins for basic research and biotechnological application. Here, the different methods and strategies to incorporate new or modified amino acids are explained in detail, including a lot of practical advice for first-time users of this powerful technique. Novel applications in protein biochemistry, genomics, biotechnology and biomedicine made possible by the expansion of the genetic code are discussed and numerous examples are given. Essential reading for all molecular life scientists who want to stay ahead in their research.

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