1.
Identification Of Pesticides Residues In Defferent Samples Of Milk
by Neelam Shahzadi | Dr. Muhammad Imran | Dr. Abu Saeed Hashmi | Dr. Muhammad.
Material type: ; Format:
print
; Literary form:
drama
Publisher: 2013Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1646,T] (1).
2.
Dna Quantification Of Blood Stains Recovered From Washed Fabrics
by Zeenat Salah-ud-din | Dr. Muhammad Yasir Zahoor | Dr. Muhammad | Dr. Muhammad Wasim.
Material type: ; Format:
print
; Literary form:
drama
Publisher: 2013Dissertation note: Bloodstains are extremely important forensic evidences for DNA profiling. Bloodstains
recovered at crime scene can help to identify and confirm the credentials of the victim. Criminal
can make all efforts to destroy and hide possible evidence at crime scene therefore these
bloodstains on the crime place can hardly provide any evidence against the culprit. The criminal
will try to take away or change clothes with the bloodstains of the victim. Once perpetrator has
removed the bloodstains, culprit will feel secure and satisfied. But as a suspect if clothes are
recovered with washed bloodstains and forensic evidence of DNA of the victim can be recovered
from the washed clothes and can provide strong evidence against suspect. Present study has been
planned to quantiate DNA from 10 different types of bloodstained fabrics with possible ways of
washing to hide the blood from fabrics. 100 ìl of preservative blood was used in creating blood
spot on fabric. After that dried bloodstained fabrics were hand washed with tap water and in
detergent for 5 and 10mins and air dried at room temperature (25°C- 30°C) in laboratory. DNA
was extracted through Chelex® 100 extraction procedure from these fabrics and analyzed on
Real time PCR kit i.e. Quantifiler™ Human DNA Quantification kit which is specific for Human
DNA. Research study showed there was no statistically significant difference in DNA
concentrations among different washing methods (p-value = 0.318). There was statistically
significant difference in DNA concentrations among different types of fabrics divided into two
categories (p-value = 0.001, 0.002). Research findings showed that cellulose fibers recovered
highest quantity of DNA, followed by artificial fibers and then protein fibers (cellulose
>artificial>protein fiber) despite their washing methods. Thus provides a lead in solving such
type of criminal cases.
Availability: Items available for loan: UVAS Library [Call number: 1663,T] (1).
3.
Development Of Latent Fingerprints On Diifferent Substrates Using Various Fruit And Vegetables Extracts
by Misbah Khan | Dr. Muhammd Yasir Zahoor | Mr. Akhtar Ai | Ms. Faiza Masood.
Material type: ; Format:
print
; Literary form:
drama
Publisher: 2013Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1667,T] (1).
4.
Gender Differentiation From Fingerprint Ridge Count In Pakistani Population
by Ahmed Fayyaz | Prof. Dr. Tahir Yaqub | Dr. Muhammad | Ms. Sehrish Firyal.
Material type: ; Format:
print
Publisher: 2013Dissertation note: In forensic science, fingerprinting has been used for decades as an efficient tool for identification of persons linked to an illegal activity or a crime scene. Different methods for the development and analysis of the latent fingerprints have been introduced including optical, physical and chemical methods. Each method has its own importance in the development and examination of the latent prints, which are invisible to naked eye before the application of fingerprint development methods. A lot of work has been published worldwide regarding fingerprinting. It was also reported that there is a significant difference in the ridge density of males and females. Ridge count might be helpful in the gender differentiation in Pakistani population. Patent prints of 100 males and 100 females were taken on A4 size paper or card paper using pelikan black inkpad and analysis was done with the help of 10x magnification lens. The ridges were counted diagonally within a square of 5mm x 5mm. This value depicts the number of ridges per 25 mm2. Results were analyzed by using Multivariate analysis of variance (MANOVA). The results of this study are used as a helpful tool for forensic expert and law enforcement. It reveals that females have finer epidermal ridge detail than males. The degree of ridge density is used as presumptive indicator of gender of unknown print left at a crime scene. First we qualitatively examine if prints appear coarse or fine and then by quickly quantifying ridge density or ridge count in a manner similar to method described in this study. The outcomes of this study will be helpful in exoneration of innocents in different crimes.
Availability: Items available for loan: UVAS Library [Call number: 1668,T] (1).
5.
Comparasion Of Differnt Presumptive Tests For Detection Of Bloodstain After Washing Fabric With Different
by Samreen Mushtaq | Ms. Sehrish Firyal | Dr. Muhammad Imran | Ms. Faiza.
Material type: ; Format:
print
; Literary form:
drama
Publisher: 2013Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1674,T] (1).
6.
Detection And Quantification Of Dna From Saaliva From Cigarette Butts In Different Genders
by Qurra-tul-Aien | Prof. Dr. Tahir Yaqub | Dr. Abu Saeed | Dr. Muhammad Imran.
Material type: ; Format:
print
Publisher: 2013Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1675,T] (1).
7.
Deoxyribo Nucleic Acid Extraction & Qantification From Human Saliva Deposited On Fruits With Human Bite
by Shahid Nazir | Dr. Muhammad Wasim | Dr. Muhammad Yasir Zahoor | Ms. Faiza.
Material type: ; Format:
print
; Literary form:
drama
Publisher: 2013Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1717,T] (1).
8.
Comparison Of Locally Available Synthetic And Non-Synthetic Powders For Latent Fingerprint Development
by Arman Khan | Dr. Muhammad Wasim | Dr. Abu Saeed Hashmi | Dr. Wasi.
Material type: ; Format:
print
Publisher: 2013Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1718,T] (1).
9.
Estimation Of Caffeine In Decaffeinated Coffee And Tea Available In Pakistan
by Muhammad Abbas Sadiq | Dr. Muhammad Wasim | Dr. Abu Saeed Hashmi | Ms. Sehrish.
Material type: ; Format:
print
; Literary form:
drama
Publisher: 2013Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1719,T] (1).
10.
To Investigate The Morphology Of Lip Prints And Their Effectiveness In Individualization And Sex Determination
by Makhdoom Saad Waseem Ghouri | Dr. Muhammad Wasim | Dr. Abu Saeed | Prof. Dr. Tahir Yaqub.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2013Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1720,T] (1).
11.
Trace Analysis Of Gun Shot Residue On Different Fabrics Using Locally Manufactured Ammunition In Pakistan
by Muneeba Butt | Prof. Dr. Tahir Yaqub | Ms. Faiza | Ms. Sehrish Firyal.
Material type: ; Format:
print
Publisher: 2013Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1733,T] (1).
12.
Estimation Of Cyanide In Different Speciis Of Apple Seed
by Zohra Bhatti | Dr. Muhammad Wasim | Dr. Abu Saeed Hashmi | Dr. Ali Raza.
Material type: ; Format:
print
Publisher: 2013Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1748,T] (1).
13.
Preservation And Developemental Study Of Bloody Fingerprints From Buried Substrates At The Crime Scene
by Shahid yousaf | Mr. Muhammad Akhtar Ali | Dr. Mohammad Ashraf Tahir | Dr. Muhammad.
Material type: ; Format:
print
; Literary form:
drama
Publisher: 2013Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1751,T] (1).
14.
Method Development And Estimation Of P-Phenylenediamine In Biological Sample.
by Muhammad Adnan Jamil | Dr. Muhammad Wasim | Dr. Abu Saeed Hashmi | Ms. Sehrish | Faculyt of Biosciences.
Material type: ; Format:
print
; Literary form:
drama
Publisher: 2013Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1754,T] (1).
15.
Level Of Amylase From Human Saliva Deposited On Fruit First Bite Mark
by Umar Draz | Ms. Sehrish Firyal | Dr. Mohammad Ashraf Tahir | Prof. Dr. Tahir.
Material type: ; Format:
print
; Literary form:
drama
Publisher: 2013Dissertation note: Saliva is colorless fluid which consists of epithelial cells, enzymes, non enzyme protein and inorganic components. Saliva is secreted by three glands in mouth. One is parotid gland, second is submandibular gland and third is sublingual gland. There are two types of amylases in human. One is salivary amylase, while other is pancreatic amylase. The salivary amylase is secreted by salivary gland while pancreatic amylase is secreted by pancreas. The salivary amylase is present in saliva, perspiration and breast milk. Pancreatic amylase is present in blood, feces and urine. Saliva stain is very important at crime scene for forensic investigation. Majority of techniques used for detection of saliva are based upon the presence of salivary amylase. Human saliva can serve for identification. One can extract DNA from saliva stain and generate DNA profile, whereby individual can be identified who is a source DNA profile that is generated from saliva stain. In present study level of salivary amylase was determined from human saliva deposited on fruit with first bite mark. Apple, peach and apricot were selected for this experiment. Ten males and ten females were selected to bite on fruits. The time interval was used as variable for determining the level of amylase. The time intervals were 0 hour, 12 hours, 24 hours, 36 hours and 48 hours. Samples were collected from bite mark area on fruit. The samples collected from apples and apricot pits were positive for amylase activity till 48 hours. The samples collected from peach were positive till 12 hours. The samples collected from peach were negative after 24 hours. This research indicates that salivary DNA could be found on bite mark area on apple and apricot pit till 48 hours.
Availability: Items available for loan: UVAS Library [Call number: 1755,T] (1).
16.
Recovery Of Latent Finger Prints From Materials Immersed Om Aqiatic Environment: The Under Water Crime Scene Investigation
by Tahir Ismail | Mr. Akhtar Ali | Dr. Muhammad | Dr. Muhammad Imran.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2013Dissertation note: Finger prints evidence is regarded as the best means of personal identification. It can also
distinguish between identical twins. The type of finger prints invisible to the naked eye is known
as latent finger prints. Recovery of latent finger prints from materials depends on a number of
factors such as type of material, environmental conditions and duration of exposure. Water
comprises about 71% of the earth. As the number of people visiting water ways (rivers, canals,
streams etc.) is increasing, the incident rate of crimes has been found to rise at these places.
Moreover, criminals find it convenient to dispose of weapons and evidences in the water ways.
Forensic science consists of a variety of techniques that are applied in order to answer the
questions of interest to legal system. Cyanoacrylate fuming and dusting powder methods are
used for the development of latent finger prints from materials immersed in aquatic environment.
By examining the characteristics of latent finger prints, on materials thrown in to water, the
forensic scientist may positively identify the perpetrator.
This research activity was conducted to evaluate the effect of type of material, immersion
medium and time length of immersion in aquatic environment, in a realistic setting, using
materials that closely resemble the common evidences. The materials comprised stainless steel
knives, aluminum foils, used brass cartridges, soft drink plastic bottles and glass slides. For every
material, sample size was kept 196. The samples were labeled with permanent identification
numbers. After deposition of finger prints by volunteers, the materials were placed in the tubs of
immersion media, one tub for each type of material. Maximum immersion time was 35 days. 21 samples of each material were taken out of water at day 5, 10, 15, 20, 25, 30 and 35. The
taken out 21 samples and 7 controls were processed for latent finger prints development, with
cyanoacrylate fuming and dusting powder methods.
Cyanoacrylate fuming was performed in a zip lock transparent polythene bag. A china
dish covered with aluminum foil and having NaOH treated cotton balls was introduced in the
fuming chamber. Samples, controls and a beaker of hot water were also placed. Cyanoacrylate
(ELFYTM) drops were put over the cotton balls and zip was closed immediately. The controls
were observed for optimum development of latent finger prints. After development, each finger
print was lifted using tape lifter, placed on a white finger print card and examined with the help
of a magnifying glass. The finger prints were assessed using a scoring system, based on the
visibility of finger prints, as adopted in various published studies.
Similar results were obtained for up to 5 days immersion in all the immersion media.
Differences arose from day 10. This time and onwards, finger prints could not be developed from
brass cartridges immersed in any media. Canal water was noted to favor the retention of latent
finger prints because suspended particles in canal water tend to adhere the latent finger prints.
Detergents in sewerage water were found to quickly wipe the latent finger prints residue.
Chlorine used as dis-infectant in swimming pools is acidic in nature. Under acidic conditions,
development of latent finger prints becomes difficult.
The data was analyzed for results by Pearson’s co-efficient of correlation using IBM SPSS
20.0 software. The study illustrated that there is correlation among type of material, immersion
medium and time length of immersion in aquatic environment. It will provide valuable
information for crime investigation agencies to establish a link between finger prints evidence
recovered from various materials immersed in aquatic environment and the suspected person.
Availability: Items available for loan: UVAS Library [Call number: 1763,T] (1).
17.
Blood Spatter Classification As A Function Of Blood Droplet Dynamics And Their Forensic Implications
by Shahid Iqbal | Mr. Akhtar Ali | Dr. Muhammad | Dr. Muhammad Tayyab.
Material type: ; Format:
print
Publisher: 2013Dissertation note: A thoroughconsideration of blood dynamics and stain creation is avital necessityto the clarification of distinct bloodstain and the spatter patterns at the crime scene. In addition the results of experimental work including studies of falling and impacting blood droplets have been presented. The magnitude of blood stains and the amount of droppers and needles round the stain fringe relays on droplet impact velocity and droplet diameter. It is not unusual to find bloodstain patterns in a violent encounter and through proper interpretation they can provide very critical details about such an event. Accurate calculations and digital photography may estimate the release height of passive droplets, the characteristics of release surface and the forces involved in bloodshed.The spattered blood pattern is used routinely in crime scene for investigators/death scene investigators to evaluate blood spattering and blood droplet impact velocity. Examination could determine the maximum resolution of bloody spots. Four different forms of stains were produced and human blood was used with heparin as an anti-coagulant (Kargeret al.1998). The blood volumes usedwere: 10 l, 5 l, 1 l, 0.5 l, 0.25 land0.1 l. Pipette (Eppendorf) and precision syringe were used for measuring and releasing the blood spattering. Blood droplets were allowed to fall freely by hand by pressing the needle of the syringe very slowly so that drops separated from the tip of a stainless steel hypodermic needle at their own mass.Respectively,all volumeswererepeated for consecutive five times to create four forms of contact stains and spatter stains on various surfaces used in the study.The resulting stains were examined with and at the end were photographed through digital camera. The results were interpreted by applying Regression coefficient relationone way Anova and two ways Anova which showed significance statistically.It will aid the crime investigation agencies to explore the importance of blood spatter analysis in crime/ death scene investigationand to estimate the creditability of reportsdelivered by the observer, prey or a doubtful.
Availability: Items available for loan: UVAS Library [Call number: 1764,T] (1).
18.
Estimation Of Various Adulterants In Milk Available In Local Market
by Farhan Tanveer | Dr. Muhammad Wasim | Dr. Abu Saeed | Ms. Sehrish Firyal.
Material type: ; Format:
print
; Literary form:
drama
Publisher: 2013Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1781,T] (1).
19.
Determination And Quantification Of P- Phenylenediamine (Ppd) From Different Brands Of Henna Available In Punjab
by Aabroo imtiaz gill | Mr.Akhtar Ali | Dr. Muhammad | Ms. Sehrish firyal.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2014Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1972,T] (1).
20.
Comparative Study Of Dust Prints Preserved By Electrostatic Dust Print Lifter (Edpl) Tape Lifting And Digital
by Afreen laeeque | Ms.Maryam javed | DR. Asif nadeem | Ms. Faiza.
Material type: ; Format:
print
Publisher: 2014Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1973,T] (1).
21.
Forensic Utilization Of Synthetic And Non Synthetic Powders And Liquid Soaps For Development Of Fingerprints On Adhesive Sides
by Sobia nosheen | Dr. Muhammad Ashraf tahir | Dr. Abu saeed | Dr. Muhammad wasim.
Material type: ; Format:
print
Publisher: 2014Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1993,T] (1).
22.
Detection And Analysis Of Traces Of Ignitable Liquids On Burnt Substeates
by Abdul basit | Akhtar ali | Dr. Abu Saeed | Dr. Muhammad Wasim.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2014Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 2007,T] (1).
23.
Molecular Variability Analysis Of Mitochondrial Dna Hypervariable Region L And Ll In Four Consecutive Human Generations of Punjab
by M. Faaras iqbal | Prof. Dr. Tahir yaqub | DR. Sehrish firyal | Miss Faiza.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2014Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 2008,T] (1).
24.
Microscopic Comparison Of Human Hair Amongst Three Male Generation Of Five Castes In Punjab Pakistan
by M. Farhan khan | Prof. Dr. Tahir yaqub | Dr. Muhammad tayyab | Dr. Sehrish.
Material type: ; Format:
print
Publisher: 2014Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 2009,T] (1).
25.
Determination Of Residual Contents Of Pesticide Using Chromatographic Techniques In Rice Samples From Different Geograohical Regions of Punjab
by Abubakar imran | Dr. Tanveer hussain | Dr. Asif nadeem | Ms. Shagufta saeed.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2014Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 2017,T] (1).
26.
A Studyof Pesticidues In Different Fruits Collected From Differentfruit Markets Of Lahore Punjab
by Muhammad shafi | Dr. Muhammad imran | Ms. Huma mujahid | Ms. Saeeda.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2014Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 2037,T] (1).
27.
Dna Typing Of Saliva Stains Recovered From Date Pits
by Madiha kiran | Dr. M. Yasir zahoor | Dr. M. Imran | Ms. Asma waris.
Material type: ; Format:
print
Publisher: 2014Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 2076,T] (1).
28.
Allele Frequency Distribution Of 15 Star Loci In Gujjar Cast Of Punjab Pakistan
by Maira shakoor | Dr. Muhammad Yasir zahoor | Dr. Tanveer hussain | Ms. Shagufta.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2014Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 2077,T] (1).
29.
Evaluation Of Different Methods Of Dna Extraction From Burnt Human Tissues And Generation Of Geneticprofiles For Identification
by Anum yousaf | Dr. Muhammad Wasim | Dr. Muhammad | Dr. Muhammad Tayyab.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2014Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 2081,T] (1).
30.
Allelic Frequency Of Short Tandem Repeats Repeats Loci In Saraiki Population Of Punjab Pakistan
by Aeman jeelani | DR. Asif Nadeem | Ms. Huma | Ms. Maryam Javed.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2014Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 2087,T] (1).
31.
Role Of Maoa Polymorphism In Criminal Violence Among Convicted Offenders
by Shahpal Shujat (2010-VA-494) | Dr. Maryam Javed | Dr. Wasim Shehzad | Dr. Saadat Ali.
Material type: ; Literary form:
not fiction
Publisher: 2016Dissertation note: Criminal violence is the violent act of crime that can be of different category such as Homicidal, Sexual and Physical violence. Criminal violent behaviour is under the control of brain having serotonergic and dopaminergic system that is under the influence of genes .MAOA gene lies under the control of serotonergic system. There are 2 polymorphic forms of MAOA gene on the basis of its activity i-e MAOA-L (Low activity allele) and MAOA-H (High activity allele). MAOA-L in males but in females MAOA-H is linked with violent behaviour in combination with environmental factors.
Blood/Saliva /Buccal swabs samples (n = 20) were collected from District Jail Sheikhupura, Pakistan Organic/Inorganic method of DNA extraction was used. Primers for PCR amplification was designed using Primer3 software. PCR products were sequenced by using Sanger method from CAMB. Violent behaviour was determined by using Buss and Perry aggression Questionare Physical aggression scoring.
Sequencing results were analyzed using CHROMAS software. Sequence alignment tool like CLUSTAL was used for aligning multiple sequences of convicted samples and compared with control (DNA mixture amplification) and standard samples and detected for SNP. Then SNP were detected for the amino acid change by using ExPASy software.SNP statistical analysis was done by calculating POPGENE software and association analysis was performed by using ANOVA.
SNP in exon 8 at locus 43591035 of MAOA was identified that was T instead of G while in exon 13 two SNPs were identified at locus 43603089 and 43603112 .Both SNPs for exon 13 was heterozygous and changes T into A .The synymous SNPs were at locus 43591035 and
Summary
73
43603089 . But the SNP at locus 43603112 was non-synonymous .The association study showed that there was no association between SNP and violence scores among convicted offenders. Availability: Items available for loan: UVAS Library [Call number: 2486-T] (1).
32.
Genetic Study Of Slc6a4 Gene In Convicted Offenders From Prisons Of Punjab, Pakistan Exhibiting Antisocial Personality Disorder Traits
by Asima Saman | Dr. Saadat Ali | Dr. M. Yasir Zahoor | Dr. M. Imran.
Material type: ; Literary form:
not fiction
Publisher: 2016Dissertation note: Antisocial Personality Disorder (ASPD) is characterized by incapacity of an individual to adapt themselves to social norms. Patients with ASPD typically have irritability problems and aggressive feelings toward other people. The serotonin transporter gene (5-HTT orSLC6A4) has been associated with regulation of serotonergic neurotransmission, mood and behaviour traits.Low levels of the neurotransmitter serotonin are believed to affect judgement, planning, and impulse control in ASPD sufferers. Genetic polymorphism in selected intronic region of serotonin transporter SLC6A4 gene was associated with antisocial personality disorder (ASPD) in convicted criminal of Punjab, Pakistan. We have selected two regions from SLC6A4 gene, which was intron 1 and exon 3.After extraction of DNA Polymerase Chain Reaction was used to amplify the extracted DNA of criminals (n=20) and control (n=10) for selected segments of intron 1 and exon 3 of SLC6A4gene. Sanger’s DNA sequencing method (di-deoxy chain termination method) was used to sequence the amplified fragments. Statistical and bioinformatics tools were used to analyse the data. Intron 1 has shown 5-HTTLPR polymorphism S allele (0.85 frequencies), LA allele (0.05 frequencies) and LG allele (0.1 frequencies) and exon 3 did not show polymorphism in criminal’s sample. The study highlights the role of SLC6A4 gene polymorphism in criminals of Punjab having antisocial personality disordertraits. Availability: Items available for loan: UVAS Library [Call number: 2576-T] (1).
33.
Sequence Analysis Of Violent Behavior Gene Among Criminals
by Jawairia Akram (2010-VA-492) | Dr. Asif Nadeem | Dr. Muhammad Imran | Dr. Saadat Ali.
Material type: ; Literary form:
not fiction
Publisher: 2016Dissertation note: Violence is defined as uncontrolled emotions problem and is a reason of violent behavior among criminals. Violence is mostly physical towards other people. MAOA and MAOB are isozymes of monoamine oxidase. MAOA is associated with aggression and violence in criminals as it affects brain structure and function which ultimately causes violence and aggression MAOA gene present on mitochondrial outer membrane encodes monoamine oxidase that degrade neurotransmitters like dopamine, serotonin, epinephrine and nor epinephrine. An SNP (MAOA-LPR) in long promoter region of MAOA alters transcriptional activity of monoamine oxidase A and have two allelic forms MAOA-L and MAOA-H. MAOA-L is low activity allele and MAOA-H is high activity allele. Different research study suggested that MAOA-L is strongly associated with criminal activity in males. Aim of the study was to analyze the sequence of extreme violent behavior gene (MAOA) among criminals. Samples (n= 20) were collected from convicted offenders. Control samples (n=20) were collected from UVAS students. Organic method of DNA extraction was used. BPAQ (Buss and perry aggression questionnaire) was also filled by all the subjects included in the study. Primers for PCR amplification were designed using Primer3 software. PCR products were sequenced bi-directionally on ABI 3130XL Genetic analyzer. Results of sequencing were analyzed using CHROMAS software. Sequence alignment tool like BLAST (Basic local alignment search tool) was used for SNPs identification. 3 intronic and 1 exonic SNPs were observed and confirmed by BLAST. Exonic SNP gave significant p values computed by Chi square calculator. However, intronic SNPs were not significant according to chi square test. SNPs identified were not found to be associated with self-reported aggression. SNP observed in exon 14 is reported to be involved in psychiatric and depressive disorders. Availability: Items available for loan: UVAS Library [Call number: 2566-T] (1).
