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1. Farriery : The Art and Science of Shoeing

by Dr. Muhammad Ashraf | Dr. Muhammad Hasan.

Edition: 1st ed.Material type: book Book; Literary form: not fiction Publisher: Islamabad: Higher Education Commission; 2005Availability: Items available for loan: UVAS Library [Call number: 636.1089785 Ashraf 18552 1st 2005 Horse] (10).

2. Bioavailability Of Gentamicin In Male Buffalo Calves

by Hasan Raza, S | Dr. Muhammad Sarwar Khan | Dr. Muhammad Ashraf | Prof. Dr. Saghir | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1994Dissertation note: The bioavailability and pharmacokinetics of Gentamicin sulphate were investigated in the same 20-male buffalo calves heal thy after intravenous administration and after intramuscular administration. The blood samples were collected at various time intervals following administration of single dose of 4 mg/kg. The concentrations of Gentamicin in serum samples were determined according to the microbiological assay described by Arret (1971). The plasma concentrations of gentarnicin at different time intervals after injections were plotted on semi-logarithmic graph paper. The bioavailability and pharmacokinetics parameters were calculated according to the method described by Gibaldi (1984). Results were expressed as mean ± SD. The peak concentration of 11.273 ± 0.4976 µg/ml reached in 31.092 ± 1.217 minutes after intramuscular injection. Keeping intravenous as standard the relative bioavailability after injection was 82.5%. The half-life was 97.29 ± 5.259 minutes after I/v injection mean ± SD, volume of distribution was 202.36 ± 8.486 ml/kg/ The volume of distribution at steady stage (Vdss ) was 214.67 ± 20.99 ml/mm. The total body clearance of gentamicin was 1.7382 ± 0.0738 ml/kg. Pharmacokinetics parameters of gentamicin were seemed to be independent of rout of administration at the dosage level applied. The pharmacokinetics evaluation by compartmental method and non-compartmental method was not found significantly different. Availability: Items available for loan: UVAS Library [Call number: 0390,T] (1).

3. A Comparative Study Of Different Anaesthetic Combinations In Equine

by Sajid Ijaz | Dr. Muhammad Arif Khan | Dr. Mubasher | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1995Dissertation note: These days the scope of anaesthesia is consistently increasing due to increase in surgical patients in veterinary practice. This change in trend is due to the awareness of the owners to different surgical problems and their solutions. They do not hesitate to get their animals treated with modern equipments and highly expensive medicine. To meet this challenge and demand of the owners, veterinary surgeons are taking keen interest to get the advanced knowledge and latest information of modern equipments and their usage in veterinary practice. In the past surgery was performed by making temporary insensibility by asphyxiation, cerebral concussion by striking wooden bowl placed over the head with a hammer and a regional anaesthesia was attained by compression of nerves and blood vessels of the region to he operated upon. But these days different sedative and anaesthetic agents are being used to make the animal desensitize from all external stimuli. These drugs are available in volatile, nonvolatile and gaseous forms. The usage of anaesthetic agent entirely depends upon the species, age, weight, temperament of the patient, nature of the operation to he performed, cost and availability of the drug. In this project three different combinations were tried in thirty animals of equine species to find out the best selection for major surgical interventions. The animals were divided into three groups often animal each. These groups were designated as Group A, B and C. Group A was anaesthetized with XylazineiPentothal sodium, Group B with Acepromazine/Pentothal sodium and Group C with Diazepam/Pentothal sodium. The efficacy of these combinations was measured on the basis of nature of induction, recumbency period, nature of recovery, different body reflexes, recording temperature, pulse, respiration, and statistical analysis of results. The analysis of the results collected during this study clearly indicated that a combination of cliazepam with pentothal sodium was a better selection for anaesthetizing equine patients. This study aslo proved that combination comprising of xylazine and pentothal sodium could he used for minor surgical interventions as it produced light surgical anaesthesia. It was concluded that a combination consisting of diazepam and pentothal sodium should be used for all types of major surgical procedures in equine practice. Availability: Items available for loan: UVAS Library [Call number: 0476,T] (1).

4. Prevalence Of G.Ilt. Namatodes In P:Heasants At Lahore Zoo/Jallo Wildlife Park & Its Chemotherapy With Oxfendazole (Oxafax) & Febental [Rintal]

by Makhdoom Najaf, Muftee | Muhammed Sarwer Khan | Dr. Muhammad Ashraf | Muhammed | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1993Dissertation note: This experiment was conducted to find out that efficacy of various anthelmintics in birds (Pheasants) for the treatment of Ascaridia, Heteraki and Trichostrungylus. Thirty six pheasants naturally infected were selected for study. They were divided into 3 groups that in A, B & C. The anthelmintics used were Rintal and Oxafax. They were given to Group A, B respectively. Group C was considered as control to know the increase in the number of eggs per gm. of feces during the experimental period, showing the increase as 2375 and 2908 and 8.34% and 32.66% on third and seventh day of experiment. Fecal samples were obtained from pheasants owing to Punjab Wildlife Department, i.e. Lahore Zoo and Jallo Wildlife Park, Lahore brought to Medicine Lab., College of Veterinary Sciences Lahore of -rye samples were done: a. Before the administration of drugs. b. After 3rd day of treatment. c. After 7th day of treatment by using MC. Master technique. As regards the efficacy of the drugs, the Rintal was found highly effective and reduced 90.58 eggs per grams of feces, Oxafax reduced 82.42%. In addition to effectiveness, Rintal was also the cheapest, anthelinintic out of two. So Rintal was recommended for field use. It was observed thak incidence of infection (Ascaridia, Heterakis) in Lahore Zoo was 25% and incidence of infection in Jallo Wildlife Park was 23% overall incidence was 24%. In Lahore Zoo the prevalence was 60.11% for Ascaridia and for 1-leterakis 38.88% whereas in Jallo Wildlife Park, Lahore it was 65.21% for Ascaridia and for Heterakis 34.78% respectively. Availability: Items available for loan: UVAS Library [Call number: 0172,T] (1).

5. Study & Comparative Efficacy Of Oral & Injectable Levamisole Against G.I.T. Nematodes In Cattle And Buffaloes

by Anwar Hayat Hanjra | Muhammed Sarwer Khan | Dr. Muhammad Ashraf | Muhammed | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1991Dissertation note: This project was designed to find out the incidence of gastrointestinal nematodes and to chalk out the comparative efficacy of Levamisole Hcl oral and Levamisole Hcl injectable (Anthelmin powder and injection) in young buffaloes and cattle upto two years of age at Lahore and adjacent areas. The therapeutic trials were conducted on both sexes of buffaloes and cattle having moderate to heavy infection. The efficacy was evaluated on the basis of reduction in EPG (eggs per gram of the faeces) by using MoMaster technique. Out of the total 300 faecal samples collected directly from the rectum of experimental animals, 128 were positive for G.I.T nematodes and incidence was found to be 42.66%. The eggs of different species of nematodes, as Neoscaris vitulorum, Haemonch, Cooperia, Ostertagia, Trichostrongylus etc. were identified from the faecal samples. It was observed that the incidence of G.I.T nematodes was 44.50% and 39.83% in buffaloes and cattle respectively. Out of the 128 positive animals ninety animals were selected for the drug trials and divided into three groups of thirty animal each i.e groups A, B and C. The anthelmin tic efficacy of Levamisol Hcl oral and Levamisol Hcl injectable against G.I.T. nernatodes was observed by administering the drug to group A and B respectively and group C was kept as non-medicated control. The efficacy was determined on basis of reduction in number of ova count discharged in faeces post medication. The percentage efficacy observed on 14th day was 96. 71% and 97. 80% in buffaloes and cattle respectively, for Levamisole Hcl oral. The efficacy was 98.62% and 98.29% in huffa1oe, and cattle respectively for Levamisole Hcl injectable. Availability: Items available for loan: UVAS Library [Call number: 0237,T] (1).

6. Comparative Study Of Acaricides (Ivermectin & Asuntol) For The Treatment Of Mange Mites In Sheep

by Allah Diwaya Khan | Muhammed Sarwer Khan | Dr. Muhammad Ashraf | Muhammed | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1991Dissertation note: Ectoparasites are major problem creaters in the smooth rearing of sheep. Ainongs the ectoparasites mange mites are of prime importance as 'they damage skin, hide and wool etc. In the present study Iverinectin and Asuntol were used for the treatment of mange mites. A single subcutaneous injection of Ivermeotin 1% at dose rate of 1 nil/adult gave a cure of 80% adjudged on day 14 post treatment. A single spray of 0.1% solution of Asuntol could eliminate the condition in 65% of the clinical cases. On the same day in the animals which were kept as control (untreated), no spontaneous recovery was noted rather the condition aggravated. Availability: Items available for loan: UVAS Library [Call number: 0238,T] (1).

7. Study Of Coccidiosis In Different Age Groups & Estimation Of Haemaglobin, Pcv And Total Proteins In Camels

by Ashfar-ur-Rehman | Muhammed Sarwer khan | Dr. Muhammad Ashraf | Mubasher | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1991Dissertation note: The present study was conducted to find out the prevalence of coccidiosis in different age groups of camels and to estimate haemoglobin concentration, packed cell volume and total serum proteins in positive cases. For this purpose study was carried out on 300 animals of different age groups of camels (calves, young and adult) brought to Lahore abattoir for slaughtering during a period between June to August 1991. The investigation showed that out of 300 animals, 29 (9.66%) were positive for coocidiosis. It was also observed that infection rate was higher in calves (25.86%) than in young (5.62%) and adult camels (6.09%). The study also indicated that the prevalence of coccidiosis remained as in the month of June (8.42%), July (9.60%) end in August (11.25%). The present investigation revealed that an average haemoglobin concentration, packed cell volume and total serum protein were 9.2 ± 0..3g/100 ml, 35..27 ± 0.46% and 8.3 ± 1.0g/100 ml of positive animals respectively.. It was recorded that 19 animals showed decrease in haemoglobin, 6 showed increase in packed cell volume and 9 showed increase in total serum protein. Availability: Items available for loan: UVAS Library [Call number: 0246,T] (1).

8. Incidence Of Surra (Trypanasomiasis) & Estimation Of Blood Glucose Protein P.,C.V. Values In Camels Grought To Lahore Abbatoir

by Saleem Ahmad, S | Muhammed Sarwer Khan | Asif Rabbani | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1991Dissertation note: Trypanosomiasis in camels caused by T. evansi occurs in both acute and chronic forms. In chronic forms huge production loss occur, i.e lower milk and meat yields. The present study had been designed to find out the incidence of the disease and estimation of blood glucose ,P.C.V. and protein level , it will eventually lead to the control of Trypanosomiasis. For the incidence, blood samples were col- lected from Lahore abattoir and the presence of Trypa- nosome was confirmed by making smear from freshly collected blood samples from the ear vein.For the haematological study blood was collected from jugular vein in the glass tube . The values of protein , PC.V. and blood glucose was estimated by standard method. Out of 500 samples 24 were proved to be positive i.e 4.80 % sample were positive.Whereas in the month of July 1991 it comes 4.16 %,In the month of Aug. 91 estimated as 5.58 % and during Sept. 91 was estimated as 4.30 %. On examining the values of serum protein ,blood glucose and Packed Cell Volume ( P.C.V.) of the positive samples they showed slight increase in protein value ,decrease in glucose value and also reduction of P.C.V. values. Their mean values were calculated as 9.55 g/100 ml,29.07 mg/100 ml and 20.25 % respectively. Availability: Items available for loan: UVAS Library [Call number: 0247,T] (1).

9. Chemotherapy Of Fascioliosis With Nitroxynil And Estimation Of Serum Bilirubin & Sgot Levels In Sheep And and Goats

by Ayaz Wazir, Malik | Muhammed Sarwer Khan | Dr. Muhammad Ashraf | Muhammed | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1991Dissertation note: Fascioliasis is one of the major economically important diseases affecting a mass population of sheep and goats in Pakistan. The present study was designed to find out the prevalence of fascioliasis in N.W.F.P., and the serum bilirubin and serum glutamic oxaloacetic transaminase activities in sheep and goats before and after treatment with Nitroxynil. In this study out of 240 sheep and 360 goats forty sheep (16.667.) and forty goats (11.117.) were found positive for fascioliasis, by applying direct smear and zinc sulphate floatation technique. The eggs per gram of faeces were done by Mc Master eggs counting technique. Serum samples of forty sheep and forty goats positive for fascioliasis and twenty sheep and twenty goats negative for the same were examined for bilirubin and SGOT activities before & after medication with Nitroxynil with a dose rate of 1 ml/20 kg body weight, sub cutaneously. The drug was highly effective in all the infected groups of the animals in eradication of fascioliasis. The efficacy of the drug in the form of the eggs per gram of faeces count was determined and was recorded as 83.907. in sheep and 85.977. in goats. The mean serum bilirubin value of group "C6" was 0.24 mg/dl, which raised to 0.61 mg/dl, in group "A and to 1.19 mg/di in group "Be". Serum Bilirubin levels of group "Co" was 0.25 mg/dl at day zero while it was 0.69 mg/dl in group "Ag" and 1.09 mg/dl in group "Eg" animals on the same day. The mean serum bilirubin values of group "C5 and Cg" remained unchanged after 14 days of treatment, while these values were 0.33 mg/dl and 0.33 mg/di in groups "As & Ag" respectively, after 14-days of medication. Similarly in groups "Ba & 8g" the reduction in serum bilirubin after 14- days post treatment also occured and the mean values were recorded as 0.62 mg/di and 0.52 mg/dl respectively. Pre-medication mean serum glutamic oxaloacetic transaminase activities in group "C5 and Cg" were 40.14 units/mi and 40.15 units/mi respectively. The level of SOOT in these groups remained unchanged after medication, while serum 60T values were 86.95 units/mi and 80.77 units/mi in group "As and AQ" and were 96.75 units/mi and 106.27 units/mi in group "B5 and Bg" respectively, before treatment. After 14 days of treatment with Nitroxynii the SOOT values of the above groups were significantly reduced, and the values recorded were 70.00 and 54.89 units/mi in "A5 and Ag" and 75.47 and 57.88 units/mi in group "Be, Bg" respectively. Availability: Items available for loan: UVAS Library [Call number: 0328,T] (1).

10. The Efficacy Of Ivomec Injection, A Broad Spectrum Anthelmintic, Against Gastro-Intestinal Nematodes & Lung Work In Sheep

by Karamat Ullah | Muhammed sarwer Khan | Dr. Muhammad Ashraf | Mubasher | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1991Dissertation note: A study was conducted to find outs the efficacy of a newly introduced, ((in Pakistan ) broad-spectrum anthelminitic injection i.e. ivomec (ivermactin H.S.D. Agvet) against the naturally infected sheep in District Guiranwala, Which were very heavily infected with G.I.T. nemtodes and lung worms. The animals were emaciated, in Diarrhoe-al condition, rough wool coat and with cough. (confirmed by feacel egg and larval count examinations). In total 90 sheep were rendemly selected for this study. They were divided into three equal group each containing 30 animals namely A, B. & C. (Group A positive for G.I.T. nematode infection, group B positive for lung worm infection and group C kept as non-medicated infected control). Group C was further divided into group C1, kept as control against the nematode infected group & Group C2 kept as control against the lung worms infected group. The drug was used according to the manufacturer recommended dosage i.e. 0.2 mg/kg body weight injection by sub-contaneous route. The drug revealed a high efficacy (100%) against the G.I.T. nematodes and lung' worm infection. The egg counting and larval of lung worms counting was performed on the 0, 3rd, 7th and 10 day of the treatment. The E.P.G. and larval count was 0 at 3rd, 7th and 10th day of treatment which indicated that this drug was 100% effective against- G.I.T. nematodes and lung worms. A 0.75 kg weight gain was seen in the treated groups while animals of control groups reduced weight. No side effects of medicine were recorded during the experiment. Availability: Items available for loan: UVAS Library [Call number: 0329,T] (1).

11. Efficacy Of Ivermectin (Ivomec) Against Mange Mites And Warbles In Goats

by Saleem Qasur | Dr. Muhammad Sarwar Khan | Dr. Muhammad | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1994Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0380,T] (1).

12. Effect Of Experimentally Induced Coccidiosis On Some Blood Parameters And Its Treatment With Three New Anticoccidial Drugs In Broilers

by Arshad Latif Arshad | Dr. Muhammed Sarwer Khan | Dr. Haji Ahmed | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1995Dissertation note: One hundred and fifty day 01(1 broiler chicks were obtained from a local hatchery. They were reared upto day 26. All the birds were given feed having no coccicliostat. At the age of 26 clays the birds were divided into five groups A, B, C, D and E. The D and B were control groups. The test groups were infected with 75000 sporulated oocysts On 26th day of age, group D was infected and non medicated while group E was kept non infected and non medicated. The group A, B and C were treated with clopidol, monensin and salinomycin respectively after the appearance of clinical symptoms. The total oocyst counts in all groups on zero day of infection were nil and on 1st, 5th and 9th day of medication, groups A, B, C, D showed 25800, 20400, 23800, 197500 oocysts counts respectively, while group B examined nil being control non infected group. The mortalities observed in groups A, B, C, D and E were 6, 2, 3, 8 and nil while percent mortality was 20%, 6.66%, 10%, 26.66% and 0.00%. In treated groups, monensin showed least mortality. The feed intake and feed conversion of groups A, B and C were almost equal. While group D (infected and non medicated) was relatively poor. As far as group E (non infected and non medicated) is concerned it showed better results. In haematological studies the average values of haemoglobin levels, erythrocytic count and total serum protein were lower post infection as compared to the respective control group E (non infected and non medicated). The total leukocytic count was increased in all groups as compared to group E (non infected and non medicated). The differential leukocytic count, the lymphocyte decreased, heterophils and monocytes increased. The eosinophils and basophils showed variation in their number. The study showed efficacy of Monensin, Salinomycin and Clopidol in descending order respectively. Monensin was to be drug of choice against coccidiosis. Availability: Items available for loan: UVAS Library [Call number: 0428,T] (1).

13. Effect Of Fascioliasis On The Blood Picture And Comparative Efficacy Of Different Fasciolicidal Drugs In Sheep

by Shazia Maqbool | Dr. Khalid Pervaiz | Dr. Mubasher | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1995Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0471,T] (1).

14. A Serological And Coprological Study Of Paramphistomiasis In Buffalo

by Jameel Ahmad | Dr. Khalid Pervaiz | Dr. Haji Ahmed | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1997Dissertation note: Two hundred faecal samples, serum samples and paramphistomes used in the present study collected from main slaughter house of Lahore and from surrounding of the city. Faecal examinations were carried out with fresh smear technique and 61.5% animals found positive for paramphistomiasis. Serum was separated from the blood samples collected from infected and suspected buffaloes for the performance of enzyme-linked immunosorbent assay. Paramphistome crude antigen was prepared from fresh stomach flukes, which contained 95.66 mg proteins/mi at 545 nm. For performing the enzyme linked immunosorbent assay, the 96 well ELISA plates were coated with crude antigen & kept overnight & then the other procedure for the assay was followed, & the serum samples were tested with paramphistome crude antigen. In positive samples, the yellowish-brown colouration was formed. In faecal examination, 61.5% and in the ELISA 100% of the animal found positive. From the conclusion of the results if was found that ELISA (100%) has given more positive results then faecal examination (61.5%). Availability: Items available for loan: UVAS Library [Call number: 0490,T] (1).

15. A Clinicopathological Study Of Lactic Acidosis In Sheep And Goats

by Usman, M | Dr. Khalid Pervez | Dr. Javed | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1998Dissertation note: A total of 100 sheep and goats suffering from lactic acidosis brought to Outdoor hospital, College of Veterinary Sciences, Lahore were selected as experimental animals while the same number was kept as control to access the events of lactic acidosis. The temperature, pulse rate, respiration rate, rumen and serum p11, serum bicarbonate, packed cell volume, ruminal movements and ruminal protozoa of the two groups were studied. It was found that rectal temperature, blood pH, rumen p11, serum bicarbonate and ruminal movements decreased significantly in acidotic group as compared to control group. Simultaneously the pulse rate, respiration rate and packed cell volume increased, significantly in lactic acidotic group as compared to control group. Mean values observed in goat were serum pH 7.075±0.11 rumen p11, 4±0.57 serum bicarbonate, 12.42±0.59 mEq/liter, packed cell volume 67.50±3.2%, temperature 100.9±0.19°F, pulse rate 168.6±3.77 per minute and respiration rate 17.00±0.82 and in sheep mean values were 7.025±0.85, 4±0.57, 12.42±0.66 rnEq/liter, 64.25±0.21%, 100.9±0.82 °F, 168.6±3.77 per minute and 17.00±0.82 per minute respectively. The rumen protozoa was found to be completely destroyed in the experimental group. There was complete ruminal stasis in lactic acidotic group. Availability: Items available for loan: UVAS Library [Call number: 0550,T] (1).

16. Comparative Efficacy Of Vetimast (Cibageigy), Tetra Delta (Upjohn) And Akamycin-D (Selmore)Against Mastitis In Buffaloes Under Field Conditions

by Razzaq, A | Dr.Iftikhar Gul Ahmad | Dr.Khushi | Dr.Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Nature of contents: biography; Literary form: Publisher: 1998Dissertation note: The present project was undertaken to study the effectiveness of 3 different intramammary preparations in buffaloes suffering from clinical mastitis in the viscinity of Lahore and District Kasur. From these cases causative organisms were isolated and j vitro sensitivity was tested with 3 corresponding antibiotic discs and chemotherapeutic trials were conducted in the field. The following salient results were obtained: 1. Out of 45 milk samples of mastitic buffaloes examined, 53.33 percent were due to staphylococci, 40 percent due to streptococci and 6.66 percent due to gram -ye rods. 2. Among 53.33% strains of staphylococci, 83.33% were sensitive to cefacetrile (Vetimast) while remaining 16.67% were resistant. 3. 83.33.2 percent staphylococci, 83.3% of streptococci and 100% of gram -ye rods were sensitive to Tetra-delta. 4. 75 percent staphylococci, 83.33 percent streptococci and 100% gram -ye rods were sensitive to Gentamycin. 5. 88.88 percent streptococci and 100% E. coli were sensitive to Cefacetrile (Vetirnast). Remaining 11.12 percent of streptococci were resistant to Cefacetrile. Ten buffaloes (Group-A) were treated with 235 mg of cefacetrile, 5 bufffaloes (50%) got cured after 7 days of the end of the therapy and 2 more (20%) animals got cured after 14 day of therapy. Ten bufffaloes (group-B) were freated with TGtra-delta, 5 (5Ob) cured after 7 days of the end of treatment and 3 more buffaloes (30%) got cured after 14 days. Similarily, 10 animals (Group-C) were treated with Akamycin-D by intramammary infusion, 4 buffaloes (40%) got cured after 7 days of therapy and 2 more animals (20%) got cured after 14 days of the end of treatment. In the present study, the total financial losses of about Rs. 43660/has been estimated to be caused by clinical mastitis in buffaloes. These losses are preventable by effective chemotherapeutic and control measures. Clinical trials conducted under field conditions in treating the clinical mastitis in buffaloes have shown that tetra delta is efficacious and economical, as it is cheaper and single dose treatment as compared to vetimast and akamycin-D which are expensive. Availability: Items available for loan: UVAS Library [Call number: 0557,T] (1).

17. Retrospective Epidemiological Study And Clinico Serological Observations On Haemorrhagic Septicaemia In Cattle And Buffaloes In District Dera Ghazi Khan During 1996

by Zaka Saeed | Dr. M. Athar Khan | Dr. M. Naeem | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1998Dissertation note: An active surveillance was conducted to understand the incidence and economic losses due to Haemorrhagic septicaemia in randomly selected 10 villages of tehsil/district Dera Ghazi Khan. The informations about the morbidity, mortality and case fatality rates related to HS were collected on a prescribed questionnaire during the previous year. The data of 4248 animals from the affected villages was cllected which included 2963 buffaloes (1042 young and 1921 adult) and 1285 cattle (417 young and 868 adults). The morbidity, mortality and case fatality rates were 22.3%, 19.64% and 88.04% in buffaloes (with 57.58%, 52.30% and 90.83% in young and 3.17%, 1.92% and 60.65% in adult animals) and 6.07%, 3.19% and 52.56% in cattle (with 8.63%, 5.27% and 61.11% in young and 4.83%, 2.18% and 45.23% in adult animals) respectively. The clinical signs observed were body temperature 104-107°F (17.39%), respiratory distress (14.61%), salivation (14.54%), nasal discharge (9.67%) and edema around throat (9.34%). The average total serum protein, serum albumin and serum globulin of diseased buffalo were 4.99g/dl, 2.60g/dl and 2.42g/dl while in diseased cattle the values were 5.78g/dl, 2.47g/dl and 2.35g/dl. Indirect haemagglutination test (IHA) used for the antibody detection against H.S. revealed that the GMT of diseased buffaloes and cattle was lower than that of healthy animals. No carrier buffalo and cattle could be detected by nasopharyngeal swabs. Economic losses due to haemorrhagic septicaemia have been estimated to be Rs. 2.615 million per annum. Availability: Items available for loan: UVAS Library [Call number: 0560,T] (1).

18. Evaluation Of Liver Functions At Varying Degrees Of Hepatectomy In Dogs

by Farhan Ahmad Atif | Dr. M. Arif Khan | Dr. Asim Aslam | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1999Dissertation note: Liver is the most important organ because of its multiplicity of functions. It played a pivotal rote in the nutrition and maintenance of the body. In this project 16 dogs were taken and divided into 4 groups comprising 4 dogs each. In group-A total removal of right lateral lobe was performed. In group-B half part of the right lobe was resected. Group-C was sham operated in which only laparotomy was experienced. Whereas, group-D acted as control. Liver function tests were conducted in all the groups before and after surgery. rfhe.e was slight elevation in the values of liver enzymes which remained within the normal range except alkaline phosphatase. Metabolic ability was not affected appreciably after resection of half and complete removal of right lateral lobe. All the dogs were euthanized after 8 weeks post-operatively. The dogs of group-B showed hepatic regeneration that was 31.2, 38.8 and 28.3 percent in dog No.6, 7 and 8 respectively. The histopathology of regenerated tissue revealed normal hepatic tissue. The analysis of results has clearly indicated that resection of liver upto this extent does not alter liver functions noticeably and thus partial hepatectomy can be performed without any fear. Availability: Items available for loan: UVAS Library [Call number: 0596,T] (1).

19. Comparative Efficacy Of Various Drugs Used Against Equine Colic

by Hamad Bin Rashid | Dr.Khalid Pervez | Dr.Asim Aslam | Dr.Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1999Dissertation note: Horse is a delicate animal and has a marked tendency towards gastro-intestinal disorders. Unlike other diseases of equines, colic provides the horse a lot pain, the veterinarian and the horse owner much anguish and loss. This study was designed to evaluate the efficacy of hyoscine-n-butylbromide, pentazocine lactate and detomidine hydrochloride. Eighteen horses suffering from colic brought to the Veterinary Hospital, Lahore Race Club, Lahore and the Outdoor Hospital, College of Veterinary Sciences, Lahore were used in this study, while 6 normal horses were kept as control. rI1i diseased horses were randomly divided into A, B and C groups. The physical examination of the affected animals was performed to determine the degree of dehydration, PCV and concentration of serum electrolytes i.e. Sodium, Potassium, Chloride and Bicarbonate were measured before treatment, 1 hour and 2 hour post treatment by flame photometry. In healthy animals PCV and serum electrolytes were in normal range. Increased PCV was observed in most of the affected horses (range 27-64% Mean 43.22%). One hour after the treatment the PCV ranged from 29.1-62.8% (Mean 43.82) while after 2 hours, It was 30.82-60.1% (Mean 43.77%). The lower values of PCV could be attributed to parasitic anaemia. Serum Sodium, Chloride and Bicarbonate concentrations were decreased i.e. 108-13 1 mEq/L (Mean 118.88), 70-91 mEq/L (Mean 79.26) and 23.3-31.1 mEq/L (Mean 26.67) respectively. While serum Potassium concentration was increased i.e. 3.0-5.4 mEq/L (Mean 4.25). One hour after the treatment the values of Nat, OF, HC03 and K were 108.8-132.4 (Mean 121.1), 74.1-94 (Mean 81.6), 24-31.4 (Mean 27.24), 3.3-5.2 mEq/L (Mean 4.39), respectively, while 2 hours after the treatment the values of Na, CF, HC03 and K were 109-133.1 (Mean 122.97), 74.5-99 (Mean 83.55), 24.5-31.9 (Mean 27.83) and 3.7-5.1 mEq/L (Mean 4.53) respectively. The efficacy of hyoscine-n-butylbromide was 100% within 5 hours post treatment. The efficacy of pentazocine lactate was 100% within 4 hours post treatment, while the efficacy of detomidine hydrochloride was 100% 4 hours post treatment. Among pentazocine and detomidine, the efficacy of detomidine was better as more horses recovered in the same time period as compared to pentazocine. Availability: Items available for loan: UVAS Library [Call number: 0599,T] (1).

20. Comp;Arative Efficacy Of Ivermectin, Levamisole And Levamisole Plus Cobalt Against Gastro Intestinal Nematodes Of Sheep Under Field Conditions In District Kohat

by Zahir Shah | Dr.Iftikhar Gul Ahmad | Dr.Haji Ahmad | Dr.Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1999Dissertation note: The present project was designed to evaluate the anthelmintic efficacy and effect of treatment on weight gain of sheep. Fighty sheep of local breed aged 8-10 months positive for gastro-intestinal nematodes were selected from surrounding areas of district 1(ohat (N.W.F.P) and were divided into 4 groups (20 animals in each group). Group A, B and C were given Ivermectin (0.2mg/kg body s/c), Levarnisole 7.5 mg/kg body orally) and Levamisole plus Cobalt (7.5 mg/kg body weight orally) respectively and group U remained as untreated control group. Egg per gram (EPG) of faeces were recorded on "0" day before treatment and on 7th, 14th, 21st and 28th days after treatment.. The efficacy of these drugs were evaluated on the basis of reduction of eggs per gram (EPG) of faeces after medication. These drugs showed a progressive decrease in the faecal egg counts. The percent efFicacy of Tvermectin, Levamisole and Levamisole plus Cobalt on 7th, day after medication was 100%, 98.65% and 98.73% respectively and on 14th, 21st and 28th days, the efficacy of all drugs was 100%. rIIIere was no significant difference (P<0.01) in effectiveness of the drugs. However, there was highly significant difference (P<0.01 between treated and control groups. The Weights of animals were recorded on "0" day before medication and on 7th, 14th, 21st and 28th days after medication. The average weight gain in group A, B and C was 1.8kg, 2.10kg and 3.21kg respectively and the percentage of increase in live weight was 6.57% in group A, 7.63% in group B and 12% in group C. Whereas members of control group reduced their weight by 1.68kg. There was highly significant difference (P<0.01) among the treatments as well as the control group. Availability: Items available for loan: UVAS Library [Call number: 0616,T] (1).

21. Prevalence Of Nematodes & Comparative Efficacy Of Albendazole, Mebendazole & Niclosamide Against Nematodes, In Wild Felidae

by Waqar Ali Khan | Dr.Khalid Pervez | Dr.Haji Ahmad | Dr.Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1996Dissertation note: The present study was conducted to estimate the efficacy of Bovisol (Albendazole), Vermox (Mebendazole) and Yomesan (Niclosamide) against nematodes i.e. Toxocara canis, Toxocara mystax and Ancylosloma braziliense in wild felidae, kept in captivity in Lahore Zoo and Lucky Irani Circus, because wild felidae are prone to a number of parasitic infection and zoological gardens served as permanent source of parasitic infestation. A survey was carried out to estimate the prevalence of Toxocara canis, Toxocara mystax and Ancvlostoma braziliense in wild felidae kept in Lahore Zoo and Lucky Irani Circus. The incidence rate of these parasites was 84.62%, 84.62% and 69.23%, respectively in the Lucky Irani Circus; and 62.07%, 48.28% and 20.69%, respectively in the Lahore Zoo. All the animals showing infection were selected for therapeutic trials. The anthelmintic trials were conducted on 19 and 13 wild felidae kept in the Lahore Zoo and Lucky Irani Circus, respectively. In each experimental Station, i.e. the Lahore Zoo and Lucky Irani Circus, four groups designated A, B, C and D were made. Groups A, B and C were treated with Bovisol (Albendazole), Vermox (Mebendazole) and Yomesan (Niclosamide), respectively. While one group i.e. D, was kept as control (untreated). The percent efficacy of each drug was determined on the basis of reduction in the number of ova discharged in the faeces of experimental animals on 7th, 14th, 21st and 28th day after medication. Results showed that Vermox (Mebendazole) and Bovisol (Albendazole) are approximately equally effective against roundworms and hookworms. Efficacy of Yomesan (Niclosamide) did not show good results throughout the experiment. The efficacy of all the three anthelmintics lowered down with the passage of time. Availability: Items available for loan: UVAS Library [Call number: 0634,T] (1).

22. A Study On The Evaluation Of Oxytetracycline Potentiation With Citric Acid, Calcium Sulphate & Terephthalic

by Adeel Sial, M | Dr.Iftikhar Gul Ahmad | Dr.Kamran | Dr.Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 2000Dissertation note: Oxytetracycline (OTC) is administered frequently in veterinary field for the treatment of infectious diseases in large animals and small animals and in the birds. 11 is readily absorbed from the intestine by most mammals but intestinal absorption in poultry is restricted. This project was designed to get more beneficial effect of oxytetracycline in poultry by adding some potentiating substances like citric acid, terephthalic acid and calcium sulphate in the diet. For this purpose 100 day old chicks were purchased from the local market. These were reared in the poultry house in the College of Veterinary Sciences, Lahore. They were provided self prepared poultry ration and water ad-lihilum for three weeks. After three weeks these birds were randomly divided into five groups A, B, C, 0 and E comprising twenty birds each. Five (lilferent experimental rations were fed for one week to each group. Group. "A" was given the ration without oxytetracycIine and was kept as control. Group "B" was given the ration with 200mg oxytetracycline per kg of ration. Similarly Group "C" was given the ration with 200mg OTC and 200mg citric acid per kg of ration. Group "I.)" and "F" were fed on ration with 5.9gm terephthalic acid (0.59%) +200mg OTC per kg of ration and 8 gm calcium sulphate (8.0%) + 200mg OTC per kg of ration respectively. The blood samples were collected at 1st, 3rd and 7th day of treatment and serum concentration of oxytetracycline was measured by using the agar well diffusion method with Bacillus subtilis using as test organism. rllhe average values of concentration of OTC in serum of group, B were 0.807±0.56, 0.897±0.63 and 0.886±0.64 on 1st, 3rd and 7th day, which indicated increase from 3rd to 7th was not significant. In group "C" the average values of OTC concentration in serum were 1.366±0.66, 1.767±0.62 and 1.657±0.67 on 1st, 3rd and 7th day respectively, which indicated that citric acid had immediate potentiating affect when mixed with oxytetracycline. however, this effect remained constant during further days of treatment. Similarly the blood serum level of OTC in group I) and E was also increased by TPA and calcium sulphate used a potentiating agents. however, these agents are not SO effective primarily as citric acid in group C. The result of the present study suggest that oxytetracycline concentration remains constant during all the days of treatment if it is supplemented alone in ration. however, in the presence of other drugs or salts used alongwith it as potentiating agents its concentration in the blood varies according to the nature of the drug or salt incorporated. Availability: Items available for loan: UVAS Library [Call number: 0636,T] (1).

23. Prevalence Of Canine Babesiosis In District Lahore & Comparative Efficacy Of Different Drugs Against Naturally Infected Dogs With Babesiosis

by Haroon Ahmad | Dr.Khalid Pervaiz | Dr. Muhammad Ashraf | Dr.S.A.Jafri | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 2000Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 0655,T] (1).

24. Magnitude Of Health Problems Of The Livestock Population, Serological Findings And Cost/Benefit Ratio At A Farmer Level

by Ajmal Shahid, M | Dr . Muhammad Athar Khan | Dr . Muhammad | Dr . Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1999Dissertation note: An active surveillance was conducted in 10% villages of canal irrigated, waterlogged, Idara-e-Kissan, river side and urban areas of tehsil Renalá Khurd district Okara through a questionnaire over a period of one year i.e. March, 1998 to February, 1999 to determine the magnitude of various livestock health problems. In total buffalo population 7333 of all the strata morbidity, mortality case fatality was 57.73%, 10.07% and 17.45% while in 2635 cattle, these observation were 38.44%, 1.25% and 3.2% respectively due to various livestock problems. In 3445 goat, 1604 sheep population, the result were 27.95%, 8.06%, 28.86% and 30.17, 9.35%, 30.99% respectively. The highest incidence of haemorrhagic septicaemia 25.38% and 6.48% in young and adult buffalo population respectively was observed in river side area. Waterlogged area was next 24.38%1and 5.165% to river side while least incidence in urban area. Foot and mouth disease incidence was highest 19.28% and 22.01% respectively in young and adult buffalo along river side with no incidence in urban area. Highest. incidence of diarrhoea 11.11% in young buffalo population was observed in waterlogged area. Similarly highest incidence of Mastitis observed was 3.07% in waterlogged area in adult cattle. The highest incidence 23.64% of FMD was observed in waterlogged areas. Incidence of enterotoxemia in young sheep population were high 18.40% than young goat 12.35% while it was high in adult goat 10.23% than 8.99% in adult sheep. Total economical losses due to various livestock disease was calculated R.8408067 (US$ 158642.77). The cost and benefit ratio at a farmer level was 1:2.03. Antibodies were detected against haemorrhagic septi caem i a through IHA, in buffalo and cattle revealed that highest GMT in vaccinated buffalo and cattle was 55.69 each. These titers were also observed in affected and unvaccinated (might be as carrier) along with the recovered animals. Availability: Items available for loan: UVAS Library [Call number: 0664,T] (1).

25. Comparative Efficacy Of Different Drugs Used Against Mange Mite Infestation In Sheep

by Zafar Iqbal, Syed | Dr . Lftikhar Gul Ahmad | Dr . Asif | Dr . Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2001Dissertation note: Parasitic inFestation arc the major problem that hinder in the smooth rearing of sheep. Among the parasitic infestations ecto parasites are of major importance. Among the ecto-parasites mange mites are of prime importance as they damage skin, hide, wool etc. Mange mile infestation is considered to be highly responsible for substantial economic losses in the livestock industry (Hourrign, 1979). The present study was conducted to determine the comparative efficacy of different drugs used against mange mites in sheep. For this purpose a total of 60 animals diagnosed positive by skin scraping technique (Tarry, 1991) were randomly divided into 3 groups (A, B and C) each group comprising of 20 animals. Group A was treated with Ivojec (Ivernwctin 1%) at a dose rate of lml/50 kg body weight. Group B was treated with Seguvon (Trichiorphon) at a dose rate of 10gm/lit/animal. Group C was kept as positive untreated control. Observations were made at one week intervals for 3 weeks. The overall efficacy of Ivermectin and Seguvon at the end of study was 90% and 80% respectively. Animals were also observed for any side effect of the product. No side effect was observed during and after the study completion in both groups i.e. A and B group. No spontaneous recovery was noted in control group. From the present study it is concluded that Ivojec (Ivermectin) is the drug of choice for the treatment of mange mite infestation in sheep. Availability: Items available for loan: UVAS Library [Call number: 0677,T] (1).

26. Effect Of Different Antimicrobials At Therapeutic Dose Level On Blood Parameters Of Clinically Normal And Diseased Sheep

by Sheraz Bashir | Dr . Muhammad Athan Khan | Dr . Muhammad Ashraf | Dr . Saghir | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 2000Dissertation note: The effect of amoxycillin, oxytetracycline and chloramphenicol at therapeutic dose level on the blood parameters of clinically normal and diseased (pyretic) sheep was studied in 18 febrile and 18 non febrile sheep for a period of 3 consecutive days. Amoxycillin treated diseased animals showed a gradual decline in temperature, pulse, respiration rate, neutrophil count, lymphocyte count, monocyte count and total serum protein, while total erythrocyte count, packed cell volume, total leukocyte count, eosinophil count and basophil counts were increased. In oxytetracycline treated affected animals, temperature, pulse, total erythrocyte count, neutrophil count, monocyte count, basophil count and total serum protein decreased while respiration rate, packed cell volume, total leukocyte count, lymphocyte count and eosinophil count increased gradually with time. In chloramphenicol treated pyretic animals temperature, pulse, respiration rate, total erythrocyte count, total leukocyte count, neutrophil count, lymphocyte count, basophil count and total serum protein decreased and packed cell volume and eosinophils increased while no effect was noted on monocyte count from day zero progressively. In amoxycillin treated non affected animals, total erythrocyte count, packed cell volume, neutrophils, lymphocytes, monocytes and eosinophil increased while pulse, total leukocyte count and total serum protein decreased and no effect was observed on temperature, respiration and basophil count. In oxytetracycline treated normal animals pulse, respiration rate, total erythrocyte count, packed cell volume, total leukocyte count and eosinophil increased while neutrophil and total serum protein decreased gradually and there was no effect on temperature, lymphocytes, monocytes and basophils. In chloramphenicol treated clinically normal animals, pulse, lymphocytes, monocytes and eosinophH increased while total erythrocyte count, total leukocyte count, neutrophil and total serum protein values decreased from day zero to onward. But there was no effect on temperature, respiration rate, packed cell volume and basophil count from day zero to day second. Availability: Items available for loan: UVAS Library [Call number: 0686,T] (1).

27. Bioavailability Of Norfloxacin After Flock Medication Via Drinking Water In Broilers

by Irfan Obaid Ullah | Dr.Muhammad Ovais Omer | Dr. Muhammad | Dr. Muhammad Ashraf | Faculty of Biosciences.

Material type: book Book; Format: print Publisher: 2004Dissertation note: This project was done to determine the plasma concentration of Norfioxacin in broiler chickens after its administration through drinking water, stability of Norfioxacin in drinking water and to check the bioavailability of two products of Norfioxacin of two different companies by using the technique of microbiological assay. In this project collected 60 birds which were divided into two groups which were further divided into six sub-groups containing 5 birds each. Two different Norfioxacin products (Norexcel given to group A and Anflox to group B) was used at the dose rate of lml/1 through drinking water and then blood samples were taken at different specific time intervals to determine the plasma concentration of Norfioxacin through microbiological assay technique. The Maximum plasma concentration (Cpmax) attained by group A was 2.700±0.0683µg/ml and group B was 2.583±0.083µg/ml. The Maximum time (Tmax) for both group A and B was 2 hours. Area under the curve for group A was 201.166 ± 3.387µg/hr/ml and for group B was 203.616 ± 2. 674µg/hr/ml and Cpmjn. for group A was 1.150±0.0428 µg/ml and for group B was 1.016±O.0401µg/ml. This project showed that Oral administration of Norfioxacin, gave better bio-availability than other routes of administration of drug. Maximum plasma concentration (Cpmax) achieved by Norfioxacin in this study is enough to check the sensitive micro-organism. The medication of Norfioxacin through drinking water is better because it remains stable in water, and its stability in water is upto 90% which checked after every 4 hours, so no suggestions for renewal of fresh solution of Norfioxacin. According to this data we concluded that the dose given in this project (1m1/l) of drinking water is enough for the treatment and cure of the bacteriological infection and this also tells that the way of medication through continuous drinking water is the method of choice for getting maximum results. Availability: Items available for loan: UVAS Library [Call number: 0889,T] (1).

28. Investigation On Epidemiology And Economics Imporatanc Eof Major And Common Livestock Diseases In Distt. Gujrat

by Mohammad Riaz | Dr. Muhammad Sarwar Khan | Dr. Asif | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1990Dissertation note: Livestock sector has faced great set back in its development programmes because of the economic losses resulting from various animals diseases. Such losses, though highly colosol in nature, had never been determined precisely in the past, hence, it became a dire necessity, the present study aimed at estimating the losses caused by various animal diseases in District Gujrat and to find out the possible contributory factors. An active surveillance was conducted, in Tehsil Gujrat. The data was collected by a survey on the basis of a comprehensive questionnaire through personnel interview of livestock owners at their places. The blood samples were collected of aborted animals and serum samples were submitted to College of Veterinary Sciences, Lahore, Laboratory for diagnosis of brucellosis. In pursuance of the present study the data was analyzed statistically and the main conclusions drawn were as under. The incidence, mortality rate and fatality rate due to H.S. were in young buffalo 14.64%, 12.40% and 84.69%. In adult buffaloes were 2.36%, 1.01% and 42.79% respectively. Diseases of various categories have been given below in order of their respective rate of mortality such as abortion 0.29% in buffalo, 0.44% in cattle and 0.08% in goat. Mastitis in buffalo 0.04%, Haeinoglobinurea in buffalo 0.46% and in cows 0.44%. Milk fever in buffalo 0.17% post parturient prolapse in buffalo 0.25%, Metritis in buffalo 0.17% and in cattle 0.22%. In case of foot and mouth disease in young buffalo incidence 5.75% and in adult 11.72%. In cattle incidence was 9.01% in young and in adult 15.11%. In case of enterotoxaeinia disease in young goat, the morbidity, mortality and fatality 0.75%, 0.75% and 100% respectively. In adult goat 10.60%, 9.83% and 92.73% respectively. In case of young sheep incidence, mortality and fatality rate were 10.08%, 9.24% and 91.66% in adult sheep 10.89%, 7.26% and 66.66% respectively. A monetary loss of Rs.1.33 million was estimated annually in buffalo and cattle, sheep and goat, due to various diseases in surveyed area in District Gujrat. It is evident from the informations gathered from the respondents that the livestock owners residing at distant places from a veterinary hospital may not comfortably utilize the hospital facilities. The village ponds as the important disease spreading factor among the livestock (Nazir al. 1978) poisonous plants and entry of new animals to herd flock with out adopting precautionary measures. Availability: Items available for loan: UVAS Library [Call number: 1139,T] (1).

29. Determination Of Bacterial Etiological Agents,Sensitivity Pattern And Clinical Outcome Of Patients With Bacterial Endocarditis at Punjab Institute of Cardiology Lahore

by Iqra fayyaz | Dr. Muhammad Adil rasheed | Dr. Milik Allah | Dr. Muhammad Ashraf.

Material type: book Book; Format: print Publisher: 2013Dissertation note: Abstract Availability: Items available for loan: UVAS Library [Call number: 1849,T] (1).



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