000 | 01515nam a2200217 a 4500 | ||
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020 | _a0126536309 (hardcover) | ||
020 | _a9780126536300 (hardcover) | ||
082 | _a616.994061 Snapka 15256 1st 1996 Genetics | ||
100 | 1 |
_aSnapka, Robert M. _93950 |
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245 | 1 | 4 | _aThe SV40 Replicon Model for Analysis of Anticancer Drugs |
250 | _a1st ed. | ||
260 |
_aUSA : _bAcademic Press, _c1996. |
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300 | _a193 p. ; | ||
490 | 1 | _aBiotechnology intelligence unit. | |
520 | _aThis book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. There is a strong emphasis on the unique advantages of SV40 as an experimental system for the analysis of these classes of anticancer drug mechanisms. The new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication are covered in detail to aid readers in designing and interpreting similar experiments. Key Features * Presents unique advantages of SV40 as an experimental system for the study of classes of anticancer drugs * Details new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication * Provides details to help the reader design and interpret similar experiments. | ||
650 |
_aSV40 (Virus) _93951 |
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650 |
_aViral genetics _93952 |
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650 |
_aDNA-drug interactions _93953 |
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650 |
_aGenetics _97478 |
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942 | _cBK | ||
999 |
_c1655 _d1655 |