000 01515nam a2200217 a 4500
020 _a0126536309 (hardcover)
020 _a9780126536300 (hardcover)
082 _a616.994061 Snapka 15256 1st 1996 Genetics
100 1 _aSnapka, Robert M.
_93950
245 1 4 _aThe SV40 Replicon Model for Analysis of Anticancer Drugs
250 _a1st ed.
260 _aUSA :
_bAcademic Press,
_c1996.
300 _a193 p. ;
490 1 _aBiotechnology intelligence unit.
520 _aThis book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. There is a strong emphasis on the unique advantages of SV40 as an experimental system for the analysis of these classes of anticancer drug mechanisms. The new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication are covered in detail to aid readers in designing and interpreting similar experiments. Key Features * Presents unique advantages of SV40 as an experimental system for the study of classes of anticancer drugs * Details new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication * Provides details to help the reader design and interpret similar experiments.
650 _aSV40 (Virus)
_93951
650 _aViral genetics
_93952
650 _aDNA-drug interactions
_93953
650 _aGenetics
_97478
942 _cBK
999 _c1655
_d1655