Comparative Immunogenic Evaluation Of Live Sheep Pox Vaccines Prepared In Vitro And In Vivo (Record no. 1969)
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fixed length control field | 02183nam a2200205Ia 4500 |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20150915135717.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 150525s1977 xx 000 0 und d |
041 ## - LANGUAGE CODE | |
Language code of text/sound track or separate title | eng |
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
Classification number | 0201,T |
100 ## - MAIN ENTRY--AUTHOR NAME | |
Personal name | Anwar Mahmood, M |
110 ## - MAIN ENTRY--CORPORATE NAME | |
Location of meeting | Ata Ur Rehman Rizvi |
245 ## - TITLE STATEMENT | |
Title | Comparative Immunogenic Evaluation Of Live Sheep Pox Vaccines Prepared In Vitro And In Vivo |
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
Year of publication | 1977 |
502 ## - DISSERTATION NOTE | |
Dissertation note | Romanian sheep pox virus was pronagate1 in milk teeth susceptible sheep using Borrel techniqne. The vaccine has a titre of 10-5 in sheep. A dose of 0.1 ml. of dilution 1:20 was recommended for each sheep. Vaccinated sheep showed a medium size (1 ½ cm- 2 cm) skin reaction at the site of inoculation and mold fever which remained for two days. Non of the vaccinated sheep showed any secondary lesions or ill effects. Confluent primary monolayer of testis cells was achieved after 48 hours, CPE started 96 hours post-infection, and 80 percent CF! was noticed on 7th post-infection day. Vaccine had titre upto 10-4.5 in vitro which correlates The titre in vivo. 0.5 Tissue culture vaccine Containing 100 TCID50 was injected sub/cut to each sheep. It conferred solid immunity. Both the vaccines withstood challenge infection with a dose of 1 ml (10,000RD) for animal given on 14th post vaccination day. 0.5 ml dose of 1:25 dilution of Romanian virus vaccine gave larger skin reaction which lead to necrosis. Therefore, 0.1 ml dose of 1:20 dilution was used in the study. 5 ml (1.00 TCID 50) of Tissue vaccine when given to sheep did not show any untoward reactions. Both vaccines gave cross protection against local sheep pox virus and are antigenically related. Both vaccines showed cross immunity with each other. The propagation of sheep pox virus in tissue culture is most economical and reliable method. Tissue culture sheep pox virus vaccine is easy to administer and is recommended for a mass vaccination/sheep pox control programme. |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical Term | Department of Microbiology |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Muhammed Yousaf Vaid |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Sheikh Altaf |
710 ## - ADDED ENTRY--CORPORATE NAME | |
Corporate name or jurisdiction name as entry element | Faculty of Veterinary Sciences |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Koha item type | Thesis |
Damaged status | Collection code | Permanent Location | Current Location | Shelving location | Date acquired | Full call number | Accession Number | Koha item type |
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Veterinary Science | UVAS Library | UVAS Library | Thesis Section | 2015-05-26 | 0201,T | 0201,T | Thesis |