The SV40 Replicon Model for Analysis of Anticancer Drugs
By: Snapka, Robert M
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Material type: 
BookSeries: Publisher: USA : Academic Press, 1996Edition: 1st ed.Description: 193 p.ISBN: 0126536309 (hardcover); 9780126536300 (hardcover).Subject(s): SV40 (Virus) | Viral genetics | DNA-drug interactions | GeneticsDDC classification: 616.994061 Snapka 15256 1st 1996 Genetics Summary: This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. There is a strong emphasis on the unique advantages of SV40 as an experimental system for the analysis of these classes of anticancer drug mechanisms. The new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication are covered in detail to aid readers in designing and interpreting similar experiments. Key Features * Presents unique advantages of SV40 as an experimental system for the study of classes of anticancer drugs * Details new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication * Provides details to help the reader design and interpret similar experiments.
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UVAS Library Genetics | Veterinary Science | 616.994061 Snapka 15256 1st 1996 Genetics (Browse shelf) | Available | 15256 |
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This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. There is a strong emphasis on the unique advantages of SV40 as an experimental system for the analysis of these classes of anticancer drug mechanisms. The new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication are covered in detail to aid readers in designing and interpreting similar experiments. Key Features * Presents unique advantages of SV40 as an experimental system for the study of classes of anticancer drugs * Details new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication * Provides details to help the reader design and interpret similar experiments.
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