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Effect Of Partial And Complete Nephrectomy On Various Blood Parasmeters In Dogs

By: Wasif Latif, Sh | Dr.Muhammad Arif Khan.
Contributor(s): Dr.Asim Khalid Mahmood | Dr.Nisar Ahmad | Faculty of Veterinary Sciences.
Material type: materialTypeLabelBookPublisher: 2003Subject(s): Department of Clinical Medicine & SurgeryDDC classification: 0814,T Dissertation note: Certain diseased conditions like renal calculi, renal cyst, malignant tumors, trauma, congenital anomalies, immune mediated, genetic, aging, poisoning, bacteria, virus and parasite leads to loss of partial or complete renal activity. This loss is usually irreversible so partial or complete removal of damaged kidney is necessary to save the animal from these life threatening conditions. The present study was undertaken to ensure the effects of partial and complete nephrectomy on various blood parameters. The purpose of any surgical procedure is restoration of normal anatomy and rapid return of function. For this purpose, partial nephrectomy and complete nephrectomy was experienced in group A and B, comprising 4 animals each. Effects of both the techniques were evaluated on the basis of clinical parameters, blood chemistry, hematological findings, radiographic examination and histopathological findings. It was observed that both the techniques are effective to save the life of animal but in completely nephrectomized dogs the values observed at different intervals i.e. 1S 4th and 8th post-operative week were recorded high. Two animals from group A were kept for longer duration i.e. 4 months in which all the values were in normal limits when tested after 4 months. On the other hand, partially nephrectomized dogs in group B showed normal clinical, biochemical and hematological values at the end of experimental period i.e. 8th week. Hence, it is concluded that loss of partial or complete function of one kidney is compensated by the contra lateral organ in the presence or by removal of damaged partner. Research has proved that both the techniques (complete and partial nephrectomy) do not bring any significant change in the biochemistry of the animal so that these techniques can be tried to save the life of patient in proportion to the extent of defect.
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Certain diseased conditions like renal calculi, renal cyst, malignant tumors, trauma, congenital anomalies, immune mediated, genetic, aging, poisoning, bacteria, virus and parasite leads to loss of partial or complete renal activity. This loss is usually irreversible so partial or complete removal of damaged kidney is necessary to save the animal from these life threatening conditions.

The present study was undertaken to ensure the effects of partial and complete nephrectomy on various blood parameters. The purpose of any surgical procedure is restoration of normal anatomy and rapid return of function. For this purpose, partial nephrectomy and complete nephrectomy was experienced in group A and B, comprising 4 animals each.

Effects of both the techniques were evaluated on the basis of clinical parameters, blood chemistry, hematological findings, radiographic examination and histopathological findings.

It was observed that both the techniques are effective to save the life of animal but in completely nephrectomized dogs the values observed at different intervals i.e. 1S 4th and 8th post-operative week were recorded high. Two animals from group A were kept for longer duration i.e. 4 months in which all the values were in normal limits when tested after 4 months. On the other hand, partially nephrectomized dogs in group B showed normal clinical, biochemical and hematological values at the end of experimental period i.e. 8th week.

Hence, it is concluded that loss of partial or complete function of one kidney is compensated by the contra lateral organ in the presence or by removal of damaged partner. Research has proved that both the techniques (complete and partial nephrectomy) do not bring any significant change in the biochemistry of the animal so that these techniques can be tried to save the life of patient in proportion to the extent of defect.

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