51.
Comparative Efficacy Of Craniodorsal & Ventral Surgical Approaches For Femoral Head And Neck Excision In Dogs
by Aamir Aslam, Ch | Dr . Muhammad Arif Khan | Dr . Asim Aslam | Dr . Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 2000Dissertation note: There are different joint problems in dogs but out of all the incidence of hip joint problems is higher. There are different problems of hip joint mainly, hip dysplasia, leg-calve-perthes disease, degenerative joint disease, irreparable fracture of acetabulum, femoral head and neck. Different methods are used as a treatment for above mentioned ailments. The methods used for such type of problems are categorized into conservative, palliative and surgical.
The surgical treatment is further divided into (1) salvage procedure i.e. femoral head and neck excision (2) total hip replacement.
The present project was launched to find out the efficacy of two approaches used for the femoral head and neck excision in dogs. The study was conducted on 18 mongrel dogs of either sex ranging in weight from 20.25 kg, which were divided into three groups of 6 dogs each.
In group A femoral head and neck excision was performed by using craniodorsal approach, whereas in group B ventral approach was used for the same procedure. Group C was kept as control in which the femoral head was luxated by using either approach. All the dogs were kept in kennels for a period of sixteen week and results were collected on the basis of clinical and radiographic evaluations. All the dogs were euthanized at the end of experimental period and operation sites were explored to find out the gross changes and also to find out the evidence of false joint formation in the muscles.
The analysis of results clearly indicated that craniodorsal approach was a better procedure than ventral approach for the femoral head and neck excision in dogs.
Availability: Items available for loan: UVAS Library [Call number: 0667,T] (1).
52.
Comparative Efficacy Of Different Drugs Used Against Mange Mite Infestation In Sheep
by Zafar Iqbal, Syed | Dr . Lftikhar Gul Ahmad | Dr . Asif | Dr . Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 2001Dissertation note: Parasitic inFestation arc the major problem that hinder in the smooth rearing of sheep. Among the parasitic infestations ecto parasites are of major importance. Among the ecto-parasites mange mites are of prime importance as they damage skin, hide, wool etc. Mange mile infestation is considered to be highly responsible for substantial economic losses in the livestock industry (Hourrign, 1979).
The present study was conducted to determine the comparative efficacy of different drugs used against mange mites in sheep. For this purpose a total of 60 animals diagnosed positive by skin scraping technique (Tarry, 1991) were randomly divided into 3 groups (A, B and C) each group comprising of 20 animals. Group A was treated with Ivojec (Ivernwctin 1%) at a dose rate of lml/50 kg body weight. Group B was treated with Seguvon (Trichiorphon) at a dose rate of 10gm/lit/animal. Group C was kept as positive untreated control. Observations were made at one week intervals for 3 weeks.
The overall efficacy of Ivermectin and Seguvon at the end of study was 90% and 80% respectively.
Animals were also observed for any side effect of the product. No side effect was observed during and after the study completion in both groups i.e. A and B group. No spontaneous recovery was noted in control group.
From the present study it is concluded that Ivojec (Ivermectin) is the drug of choice for the treatment of mange mite infestation in sheep.
Availability: Items available for loan: UVAS Library [Call number: 0677,T] (1).
53.
Effect Of Different Antimicrobials At Therapeutic Dose Level On Blood Parameters Of Clinically Normal And Diseased Sheep
by Sheraz Bashir | Dr . Muhammad Athan Khan | Dr . Muhammad Ashraf | Dr . Saghir | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 2000Dissertation note: The effect of amoxycillin, oxytetracycline and chloramphenicol at therapeutic dose level on the blood parameters of clinically normal and diseased (pyretic) sheep was studied in 18 febrile and 18 non febrile sheep for a period of 3 consecutive days.
Amoxycillin treated diseased animals showed a gradual decline in temperature, pulse, respiration rate, neutrophil count, lymphocyte count, monocyte count and total serum protein, while total erythrocyte count, packed cell volume, total leukocyte count, eosinophil count and basophil counts were increased. In oxytetracycline treated affected animals, temperature, pulse, total erythrocyte count, neutrophil count, monocyte count, basophil count and total serum protein decreased while respiration rate, packed cell volume, total leukocyte count, lymphocyte count and eosinophil count increased gradually with time. In chloramphenicol treated pyretic animals temperature, pulse, respiration rate, total erythrocyte count, total leukocyte count, neutrophil count, lymphocyte count, basophil count and total serum protein decreased and packed cell volume and eosinophils increased while no effect was noted on monocyte count from day zero progressively.
In amoxycillin treated non affected animals, total erythrocyte count, packed cell volume, neutrophils, lymphocytes, monocytes and eosinophil increased while pulse, total leukocyte count and total serum protein decreased and no effect was observed on temperature, respiration and basophil count. In oxytetracycline treated normal animals pulse, respiration rate, total erythrocyte count, packed cell volume, total leukocyte count and eosinophil increased while neutrophil and total serum protein decreased gradually and there was no effect on temperature, lymphocytes, monocytes and basophils. In chloramphenicol treated clinically normal animals, pulse, lymphocytes, monocytes and eosinophH increased while total erythrocyte count, total leukocyte count, neutrophil and total serum protein values decreased from day zero to onward. But there was no effect on temperature, respiration rate, packed cell volume and basophil count from day zero to day second.
Availability: Items available for loan: UVAS Library [Call number: 0686,T] (1).
54.
Serological Investigations Into Caprine Brucellosis
by Zulfiqar Ahmad | Dr . Khalid Pervez | Dr . Mubashar | Dr . Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 1985Dissertation note: In the present study an attempt was made to measure the incidence of brucellosis in goats. A total number of five hundred blood samples were collected from animals including 237 males and 263 females, belonging to various age groups, different sources and different breeds. The clear serum was separated and subjected to microscopic slide agglutination test and serum tube agglutination test. On the basis of microscopic slide agglutination test 5.2% goats were found positive for brucellosis. By serum tube agglutination test the percentage of positive cases was 1.2%. A total number of 159 milk samples from the individual animals were subjected to milk ring test. Of these samples 5.03% were found positive for the disease.
A comparison amongst the methods used for diagnosis of brucellosis indicated that serum tube agglutination test was the most reliable test for diagnosis of caprine brucellosis. Anyhow, the other two test can be used for screening under field condition. The overall incidence of caprine brucellosis recorded in this study was 1.2%
Availability: Items available for loan: UVAS Library [Call number: 0702,T] (1).
55.
Sero-Epidemiological Study Of Various Livestock Diseases And Cost/Benefit Raio At Farmer Level In Tehsil Dera Ghazi Khan
by Shafiq-ur-Rahman | Dr. Muhammad Athar Khan | Dr. Muhammad | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 2002Dissertation note: The epidemiological surveillance was conducted in 10% villages of Tehsil Dera Ghazi Khan which consisted of three different categories i.e. Urban, Rural and Tribal. These 10% villages were randomly selected and epidemiological survey was done during a period of one year i.e. August, 2000 to July, 2001 to determine the magnitude of various livestock diseases.
In the buffalo population of 9649 head, morbidity, mortality, case fatality rates were 61.50%, 14.41% and 23.43% while in 9224 cattle, these observations were 41.98%, 2.48% and 5.90% respectively due to various livestock diseases. In 2318 camel population morbidity, mortality and case fatality rates were 30.62%, 6.90% and 22.53% respectively. In goat population morbidity, mortality and case fatality rates were 34.54%, 11.20% and 32.42% respectively. In sheep population the morbidity, mortality and case fatality rates were 37.80%, 11.15% and 29.49% respectively.
The highest incidence was due to haemorrhagic septicaemia i.e., 29.50% in young and 6.28% in adult buffalo population of rural category. In urban category, incidence rate was 13.51%, 6.10% in young and adult buffalo population respectively, while least incidence in tribal category where it was 1.80%, 4.21% in young and adult buffalo population. The highest incidence of Foot and Mouth disease was 20.48%, 23.76% in young and adult buffalo population of rural category with no incidence in urban and tribal area.
Highest incidence of idiopathic diarrhoea of 11.62% in young buffalo population was observed in rural category. Similarly highest incidence of mastitis 5.84% recorded in buffalo population of rural category. In cattle, highest incidence of mastitis 2.74% observed in rural category. The highest incidence of Foot and Mouth disease 25.45%, 26.89% observed in young and adult cattle population of rural category.
Incidence of enterotoxemia 18.44% in young sheep population was higher than young goat 12.50%, while it was high in adult goat 12.42% than in adult sheep 9.12% respectively.
The GMT was recorded highest in vaccinated buffalo and cattle while found lowest in affected buffalo and cattle respectively.
Total economical losses due to various livestock diseases was calculated Rs.16726578/-. The cost and benefit ratio at a farmer level was 1:1.73.
Availability: Items available for loan: UVAS Library [Call number: 0739,T] (1).
56.
Effect Of Ivermetin On Liver At Therapeutic And Higher Doses In Healthy And Diseased Dogs
by khawar Qayyum | Prof.Dr.Muhammad Ashraf | Dr. Asim Aslam | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 2002Dissertation note: The project was designed to evaluate the efficacy of ivermectin against external parasites as well as its toxicity on liver at therapeutic and higher doses in healthy and disease (positive for external parasites) dogs of local breeds. For this purpose forty dogs were selected and divided into four groups (A, B, C and D) comprising 10 dogs in each. Dogs of groups A and B were healthy while dogs of group C and D were positive for external parasites. Dogs of group A were administered ivermectin at therapeutic doses (0.2mg/kg body weight subcutaneously) while of group B were given ivermectin 10 times higher dose (2mg/kg body weight subcutaneously). Similarly dogs of group C and D positive for external parasites were given normal and higher doses of ivermectin respectively. To assess the efficacy of ivermectin, skin scrapping examination was performed before and after treatment, while to evaluate the toxicity alkaline phosphatase and alanine aminotransferase enzyme activity was measured before and after treatment. The results indicated that ivermectin was quite effective against external parasites 70% and 80% at therapeutic and higher doses respectively, but the efficacy against ticks was 100% at both the dose rates without any side effect except in one dog showing irritation at the site of injection at the higher dose of ivermectin. Liver enzyme study indicated that alkaline phosphatase was not altered significantly in diseased or healthy dogs at low or higher doses of ivermectin. Alanine aminotransferase activity was also not altered significantly in diseased as well as in healthy dogs. Therefore it is concluded that ivermectin is a safe drug for the treatment of ectoparasites in local breeds of dogs.
Availability: Items available for loan: UVAS Library [Call number: 0742,T] (1).
57.
Comparative Efficacy Of Yucca Schidigera Extract And Frusemide In Ascites Of Broiler Chicks, Under Field
by Sohail Ejaz | Prof.Dr.Muhammad Ashraf | Dr. Masood | Dr. Muhammad Athar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 2002Dissertation note: This project was designed to study the comparative efficacy of Yucca schidigera extract Norponin-200) and frusemide in ascites of broiler chicks. For this purpose twenty flocks affected from ascites were selected to carry out this experiment. From each flock thirty birds were randomly selected and were divided into three groups A, B and C having ten birds in each group. Twenty-four hours light was provided to all the experimental birds. Fresh and clean water was provided to them at all the time. The birds were fed ad libitum. The chicks of group "A" were given Yucca schidigera Extract (Norponin-200) at the rate of 10ml/200L of drinking water for three days. The chicks of group "B" were given frusemide (Frusicon) at the rate of 1gm/liter of drinking water for three days while the chicks of group "C" served as control. In this study feed intake, water intake, weight gain and reduction in the ascitic fluid was recorded before and after the treatment. The treated birds were significantly better than untreated birds. In Yucca schidigera treated birds, feed intake, water intake and weight gain was significantly higher than that of frusemide treated birds while reduction in ascitic fluid was significantly higher in frusemide treated group. From this study it is concluded that use of Yucca schidigera extract in ascites of broiler chicks is a better choice than that of frusemide.
Availability: Items available for loan: UVAS Library [Call number: 0744,T] (1).
58.
Cholecystoduodenostomy As A Surgical Attempt To Establish Biliary Redirection In Dogs
by Hamid Akbar | Mr. Muhammad Arif Khan | Dr. Muhammad | Dr. Muhammad Athar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 2002Dissertation note: Liver is the largest paranchmatous organ of body. Gall bladder is embedded in lobes of liver and it acts as a store house of bile. Liver pours its secretion into gall bladder which temporarily stores it and transports it to duodenum by bile duct which is a small pathway.
Sometimes this pathway (bile duct) is disturbed due to any of multiple reasons described earlier and bile is not transported. Hence there is an immediate need to develop a new connection to restore flow of bile. Cholecystoduodenostomy is a good technique in such cases to restore bile flow. In this project twelve healthy dogs were selected and divided into 3 groups namely, A, B and C. Group A consisted of 8 dogs in which cholecystoduodenostomy was performed. Group B consisted of 2 dogs, in which only laparotomy was experienced, whereas group C also consisted of 2 dogs acted as control.
Liver function tests were carried out in all the dogs before and after surgery. The enzyme values were increased when tested at 8 weeks post-operatively. The dogs were also monitored for various parameters to check the efficacy of technique.
All the dogs were euthanized at 12th week post-operatively to chck healing at surgical site. The analysis of results has clearly indicated that cholecystoduodenostomy is a safe and sound method in obstructive bile duct problems, and this technique can be used without putting the patient in dilemma.
Availability: Items available for loan: UVAS Library [Call number: 0745,T] (1).
59.
Comparative Prevalence And Chemotherapy Of Pasciolosis In Cattle Of Lahore And Attock Areas
by Tahir Hamid | Dr. Muhammad Sarwar Khan | Dr. Haji Ahmad | Dr. Muhammad Athar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 2002Dissertation note: This project was designed to study the comparative prevalence of fasciolosis in cattle in two different areas (plane area and sub-hilly area) having different climatic and environmental conditions in terms of temperature, humidity, rain fall and water resources etc. For the purpose, Lahore and Attock were selected. In this present study, the efficacy of newly introduced homeopathic drug "Trematox" against fasciolosis in cattle was determined by comparing it with nitroxynil (Trodax 34%) and Albendazole (Farbenda 10%).
The prevalence was observed in such a way that at both the places i.e. Lahore and Attock, the animals were examined to select 80 positive cases (40 at Lahore and 40 at Attock). Subsequently, the animals were divided into 8 groups i.e. A, B, C, D, E, F, G and H. Groups A, B, C and D were kept at Lahore and groups E, F, G and H were kept at Attock. Groups A and E were untreated control groups.
The eggs per gram (EPG) counts are estimated by using McMaster technique at day zero (before medication) and day 7. Then groups B&F, C&G, D&H were treated with Nitroxynil, Albendazole and Trernatox, respectively. Nitroxynil and Albendazole were used @ 10 mg/kg body weight each. The Homeopathic drug "Trematox" was injected 5 ml to each animal i/rn.
At day 7, post-medication the EPG was measured. It was observed that at 7th day Nitroxynil showed the efficacy of 92.49%, Albendazole 77.77% and Trematox 42.75%. No side effects in any animal were observed during the experiment. Hence Nitroxynil, Albendazole and Trematox were concluded to be the safe drugs against fasciolosis in cattle.
It was observed that medium temperature between 10-25°C and high humidity offer optimal conditions for the occurrence of fasciolosis.
Availability: Items available for loan: UVAS Library [Call number: 0757,T] (1).
60.
Prevalence Of Clinical Mastities And Diagnosis Of Subclinical Mastitis In Cross Bred Cows
by Muhammad Yaqoob | Dr. Muhammad Sarwar Khan | Dr. Muhammad | Dr. Muhammad Athar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 2002Dissertation note: The study was conducted to find out the prevalence of clinical mastitis and diagnosis of subclinical mastitis in crossbred cows in and around Lahore. One hundred crossbred cows were selected in and around Lahore.
The data for clinical and subclinical mastitis was collected by different means such as observation, palpation of udder, by streaks and surf field mastitis test. Prevalence of clinical mastitis was estimated by collected data. In this project the prevalence of clinical mastitis was 14.23%.
Prevalence of clinical mastitis in different farms was different. In three selected farms "Farm A, Farm B and Farm C", the prevalence of clinical mastitis was 16.66%, 12.72% and 13.33% respectively. For diagnosis of subclinical mastitis, samples were collected from selected farms. One hundred crossbred cows were selected. Two different tests were applied for diagnosis of subclinical mastitis such as surf field mastitis test and white side test. The overall percentage of subclinical mastitis was 12.62% with both tests. The percentages of three farms were as such 10%, 14.54% and 13.33% respectively.
Availability: Items available for loan: UVAS Library [Call number: 0762,T] (1).
61.
Comparative Efficacy Of Various Suturing Techniques For End To End Anastomosis Of Jejunum In Dogs
by Abdul Rauf, Rana | Dr. Muhammad Arif Khan | Dr. Muhammad | Dr. Muhammad Athar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 2002Dissertation note: Diseases of gastro-intestinal tract like intestinal foreign body, intussusception with obstruction and adhesion, gangrene, volvulus and abdominal trauma amenable to surgical correction with enterectomy, segmental resection and end-to-end anastomosis had been a nightmare with both human and veterinary surgeons. Most of the techniques evolved in the past were not commensurate with the criteria of physiological restoration of normality, absence of leakage and minimal lumen stenosis. The present study was undertaken to compare the three suturing techniques viz; simple interrupted crushing sutures, simple interrupted lembert sutures and simple continuous lembert sutures for end-to-end anastomosis. Study was conducted on 12 clinically healthy dogs of mixed breed divided equally into three groups.
The versatility and comparison of the techniques were evaluated on the basis of clinical parameters, hematological value, radiographic examination and postmortem findings.
It was observed that simple interrupted crushing technique was comparatively more compatible and superior due to its simplicity, economical, less lumen reduction as compared to other techniques viz; simple interrupted Lembert technique and simple continuous Lembert technique.
The results of this study clearly indicated that the use of simple interrupted crushing sutures has an edge over the simple interrupted lembert suture and simple continuous lembert sutures for end-to-end anastomosis of jejunum in dogs.
Availability: Items available for loan: UVAS Library [Call number: 0766,T] (1).
62.
Effect Of Exposure Of Organophosphate Insecticide (Trichlorfon) On The Health Status Andweight Gain In Broiler Chicks
by Misbah Zulfiqar | Dr. Muhammad Sarwar Khan | Dr. Khalid Pervez | Dr. Muhammad | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 2002Dissertation note: The investigation was conducted to study the effects of organophos)hate insecticide Trichlorft)n (Nawagon) on heal Lii status, weight gain in broiler chicks and to see the elTicacy ol atropinc sulphate against this problem. Seventy five day old broiler chicks were reared upto 3 weeks of age under proper managemental conditions. At the end of 2nd week they were randomly divided into 5 groups i.e. A, 13, C, D and E containing 15 chicks in each group. Group A was maintained on a Iced containing Nawagon at dose rate of 20mg/kg in feed. Group B was maintained on a feed containing Nawagon at dose rate of 50mg/kg in feed . Group C was maintained on feed containing Nawagon at dose rate of 100mg/kg in feed. Group D was maintained on feed containing Nawagon at dose rate of 200mg/kg in feed. Group E was kept as control. A-Il the groups were maintained on this feed for 7 clays. The weights of birds from each group were taken bebore treatment with Nawagon.
The symptoms were recorded thrmighout the experiment and observed (hat during 4th week fteci intake of all the treated groups was decreased, growth was retarded significantly. Group A and B showed no symptoms. There were 3 mortalities in group C. The postmortem findings were small haemolThages throughout the body muscles liepatoinegaly, spleenomegaly, enlarged heart, swollen kidneys. All other birds of group C showed dyspnea, tremor exhaustion, in coordination and dropping of wings.
There were no mortalities in group D but birds showed dyspnea, tremors, exhaustion, in coordination, ataxia, dropping of wings and paralysis of legs. So some birds were disable to walk at the end of 4111 week.
During 5th week the birds of group C and D were treated with atropine sulphate. At the end of 3rd or 4th day of' 5 week. The birds were normal. Feed intake and growth was normal. Legs were normal. At the end of 6th week all the birds of treated group showed normal behaviour when compared with the control group. No clinical signs were observed in liver, heart, spleen and kidneys of group E (control).
Availability: Items available for loan: UVAS Library [Call number: 0768,T] (1).
63.
Prevalence And Chemotherapy Of Ascariasis In Cross-Bred Calves In And Around Lahore
by Waqar Ahmad | Dr. Muhammad Sarwar Khan | Dr. Khalid Pervaiz | Dr. Muhamad | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 2002Dissertation note: The present project was designed to find out the prevalence of ascariasis in cross-bred calves in and around Lahore and to evaluate anthelmiiitic efficacy of albendazole, oxfendazole and fumaria parviflora against ascariasis.
For this purpose the faeces of 203 cross-bred calves under 3 months aged from various localities in and adjoining city of Lahore were examined for the presence of ascariasis. Forty calves were found positive. It was observed that the prevalence of ascariasis was 19.62%. Forty naturally infected calves having moderate to heavy infection were divided into 4 groups A, B, C and D, each having 10 calves. Ten calves were acted as non-infected and non-medicated (control) as group E. The anthelmintic efficacy of albendazole, oxfendazole and fumaria parviflora was studied by administering to group A, B and C respectively.
The efficacy of the drug was determined on the basis of reduction in number of ova count, present in the faeces after medication.
Anthelmintic efficacy of albendazole (@ 5mg/kg body weight), oxfendazole (@ 4.5mg/kg body weight) and fumaria parviflora (@ 2gm/kg body weight) was observed to be 83.67%, 95.09% and 0% at clay 5 respectively and at 10 days 99.65%, 100% and 20.15% respectively.
It was found that systamex was the most effective drug for the treatment of ascariasis in crossbred calves. Second was the albenclazole. None of these drugs produced any side effects.
Availability: Items available for loan: UVAS Library [Call number: 0770,T] (1).
64.
Epidemiology Of Parasitic Load And Therapeutic Control Against Ecto And Endorparasites With Ivermectin In Horses
by Rubina Hassan | Dr. Muhammad Athar Khan | Dr. Muhammad Sarwar Khan | Dr. Talat | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 2002Dissertation note: The present research project was designed to study the efficacy of ivermectin i.e. LG EUVECTIN inj. against ectoparasites, endoparasites and blood parasites in horses. For this purpose, apparently healthy, weak, emaciated horses showing the clinical signs of parasitism, brought to Outdoor clinics, University of Veterinary & Animal Sciences, Lahore and Society for Prevention of Cruelty to Animals (S.P.C.A) were checked. Out of these 84 animals 25 (29.76%) were found positive for ectoparasites through the skin scraping examination under the microscope. From these 84 animals 28 were checked for endoparasites and through the coprological examination 25 (89.29%) were found positive. From 84 horses, 5 (5.95%) horses had mixed type of infection i.e. positive for both ecto- and endoparasites.
Ectoparasites found in 25 positive cases were mites (29.76%) and no ticks or lice infestation was found i.e. Zero percent prevalence. The endoparasites found were mainly the G.!. T. nematodes (round worms) i.e. 25 (89.29%) cases were positive for round worms while 2 (7.14%) cases out of these 25 were also infested with tapeworms and liver tlukes were zero percent.
Infected horses were treated with LG Euvectin injection (Ivermectin 1.0% w/v) through subcutaneous injection at dose rate of 1 ml/50kg (0.2mg/kg) body weight once on zero day. Eggs per gram of faeces (EPG) was counted on a day, 7th and 14th day. Recovery rate with ivermectin against ectoparasites and endoparasites was 76% and 88% respectively. A total of 50 horses were bleed for blood parasites, none of them were found positive.
Availability: Items available for loan: UVAS Library [Call number: 0791,T] (1).
65.
Prevalence And Chemotherapy Of Nematodes Infestation In Wild And Dometic Pigeons And Its Effects On Various Blood Components
by Tauqeer Basit, M | Dr. Khalid Pervez, Prof.CMS | Dr. Muhammad Sarwar Khan, Associate | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 2003Dissertation note: Apparently healthy one hundred wild and one hundred domestic pigeons were purchased from the local market which were kept for a period of thirty days under observation. They were subjected to coprological examination for the presence of nematode eggs. One group of forty naturally infested wild pigeons and other group of forty domestic pigeons were selected. They were infested with Ascaridha columba, Capillaria obsginata and Ascaridia gjj one or more type of nematodes.
All the forty domestic pigeons as well as forty wild pigeons were divided into eight groups comprising of ten pigeons each. Among the domestic pigeons three groups i.e. D1, D2 and D3 were treated with Ivermectin, Oxfendazole and Piperazine respectively while the fourth group i.e. CD was titled as an un-treated control group. Similarly the three groups i.e. WI, W2 and W3 of wild pigeons were treated with Ivermectin, Oxfendazole and Piperazine respectively while the fourth group i.e. CW was kept as controlled untreated group. Egg per gram was done on day zero, tenth and twenty first day of experiment. On zero day of experiment after taking the fecal samples Ivermectin, Oxfendazole and Piperazine were administered in DI and WI, D2 and W2, D3 and W3 groups of pigeons respectively.
The efficacy rate of Oxfendazole, Ivermectin and Piperazine in the domestic pigeons was 60%, 100% & 80% respectively while the efficacy percentage for wild pigeons was 50%, 100% and 80% with the treatment of Oxfendazole, Ivermectin and Piperazine.
The Ivermectin treated group showed the best results in term of lowest EPG st day post treatment and hemoglobin estimation was maximum i.e. 10.8mg/dI in DI and WI as compared to control group. Similarly TLC was minimum i.e. 0.2million Ofl 21st day of the experiment in the lvermectin treated group of domestic pigeons.
Availability: Items available for loan: UVAS Library [Call number: 0794,T] (1).
66.
Comparative Efficacy Of Intramedullary Pilling And Cerclage Wiring For The Repair Of Long Oblique Tibiotarsus Fracture In Avian
by Waqar Azeem | Dr.Muhammad Arif khan | Dr. Muhammad | Dr.Asim Khalid Mahmood | Faculty of Veterinary Sciences.
Material type: ; Format:
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Publisher: 2003Dissertation note: The present project was designed t find out most effective and accurate method of internal fixation in avian long oblique tibiotarsal fracture repair. For this purpose 12 indigenous chickens of both sexes were selected and randomly divided into three groups i.e. A, B and C comprising four birds each. Long oblique tibiotarsal fractures were created in either of the limb. In group A these fractures were repaired with single intramedullaiy pin. K.E. wire f 2.5mm diameter was used for this purpose. In group B, 2 - 3 full cerclage wires were applied where as both these techniques were used simultaneously in the birds of group C to achieve the goal of fracture stabilization. The birds were kept uptil 8 weeks post operatively. The fracture healing procedure was monitored on weekly basis. The birds were slaughtered at the end of experiments period and postmortem examination was conducted to see the gross lesion over the fracture site. The data thus obtained from the results revealed that the use of single intra medullaiy pin along with 2 - 3 full cerciage wire application showed an excellent and smooth healing potential for the repair of long oblique tibiotarsal fracture.
Availability: Items available for loan: UVAS Library [Call number: 0828,T] (1).
67.
Effect Of Replacement Of Feed Additive Antibiotics (Flavomycin)With Differet Levels Of Propionic Acid,On Bralier
by Hafiz Nadeem Ahmad Nasir Bhatti | Dr.Muhammad Athar khan | Dr. Muhammad | Dr.M.Sarwar khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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; Literary form:
not fiction
Publisher: 2002Dissertation note: Main theme of this study was to seek out the effects of replacement of feed additive antibiotic (Flavomycin) with different levels of propionic acids on broiler performance.
To conduct this study a private poultry farm was chosen to see the results in field condition and parameters observed were growth rate, feed intake, feed efficiency, mortality and economics. Two hundred day-old broiler chicks were randomly divided into 5 groups of 40 chicks each. These birds were examined for 42 days. Group A was the control group, whereas groups B, C and D were supplemented with 0.4%, 0.6% and 0.8% propionic acid, respectively. F'lavornycin was supplemented in feed for group E.
The data thus collected was analyzed statistically. The results showed that group A (control) served to be the best with minimum feed intake. Group-B (0.4% propionic acid) resulted in good FCR, more feed intake but was not economical. Group-C (0.6% propionic acid) did not prove beneficial in any aspect whereas group-I) (0.8% propionic acid) proved good weight gain, more feed consumption, but it was not economical. Group-E (Flavomycin) consumed more feed and resulted in good weight gain. This was the only group which proved economical supplementation.
It was concluded that production results gained by Flavomycin (growth promoting antibiotics) were better than the addition of propionic acid (organic acid) but propionic acid also improved production results. The use of propionic acid was not economical as compared to Flavomycin. Overall results of propionic acid were poorer than Flavomycin but better than control.
Availability: Items available for loan: UVAS Library [Call number: 0833,T] (1).
68.
Chemotherapeutical And Hematological Studies Of Experimentally Induced Cocidiosis In Pigeons
by Rashid Ghaffar | Dr. Khalid Pervez | Dr. Kamran | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
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; Literary form:
not fiction
Publisher: 2004Dissertation note: This project was designed for the Chemotherapeutical and Haematological studies of induced coccidiosis in pigeons. For this purpose three anticocidials were used. These were ancoban (Amprolium), Supercoc (Sulphaquinoxaline) and Phytocox (Herbal Product). These were used alone and with the addition of vitamin A and K. Some Haematological Studies were also done i.e. total Leucocytic Count (TLC), differential leucocytic count (DLC) and Haemoglobin (Hb) estimation.
One hundred and twenty healthy young pigeons were obtained and were provided coccidiosis free feed. These pigeons were divided into eight groups viz; A, B, C, D, E, F, G, and H comprising 15 birds each. 30,000 viable sporulated oocysts were inoculated directly into the crops of pigeons of group A to G.
The medication was started on day 4 post-inoculation of oocysts. Group A, B and C were given Ancoban, Supercoc and Phytocox, respectively. Groups D,E and F were given Ancoban, Supercoc and Phytocox (Herbal Product), respectively with the addition of vitamin`A and K. The Group G was infected, untreated control while group H was uninfected, untreated (Healthy) control. The clinical signs were more pronounced in the groups that were treated without the addition of vitamin A and K.The highest efficacy of the drug was found in group E which was 99.36%.
Haemoglobin estimation was done on day 0, 4, 9 and day 14. It was concluded that haemoglobin values were decreased after clinical signs had appeared. Total leucocytic count was also done on day 0, 4, 9 and day 14. There was increase in TLC after infection had occurred and started to decrease after day 9. The differential leucocytic count, lymphocytes decreased while heterohils and monocytes were increased and eosinophils and basophils showed variation in their number was compared to control group. The oocyst count was done on day 4, day 9 and day 14 post-inocultion of oocyst. The efficacy of the drug given to the group E was 99.40% which was the best among all the groups.
The result of the present study showed that supercoc (sulphaquinoxaline) with addition of vitamin A and K was comparatively better drug for the control and treatment for cocidiosis in pigeons.
Availability: Items available for loan: UVAS Library [Call number: 0841,T] (1).
69.
Comparative Efficacy Of Herbal, Homoeopathic And Standard Drugs Against Coccidiosis In Broilers
by Muhammad Ali | Dr. Muhammad Athar khan | Dr. Khalid | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2002Dissertation note: The study was designed to compare the efficacy of four different drugs against coccidiosis. A total 240 day old broiler chicks were purchased and reared for 42 days under standard managemental condition. The birds were randomly divided into six groups comprising of 40 birds each. Group-A was medicated with Anjbar, Group-B medicated with Bael, Group-C medicated with Mere sol, Group-D medicated with Darvisul liquid. Group-E was kept as infected, unmedicated, while group-F served as uninfected, unmedicated control. All groups except that of group-F were given challenge dose of infection on day 22nd. The oocysts were counted on 5th, 6th, 7th, 8th, 9th and 10th day post-infection. The weight gain and feed consumption were recorded weekly. Record of mortality was maintained and postmortem of dead birds was performed. The data collected was subjected to statistical analysis using two way analysis of variance and least significant differences between treatment.
It was concluded that Aegle Marmelos (Bael fruit) and Darvisul liquid showed better results in term of wight gain, feed consumption, reduce oocyst count, as compared with Anjbar and Merc sol
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70.
Effect Of Prophylactic Measures Against Coccidiosis In Broiler Breeder Chicks
by Imtiaz Ahmad | Prof.Dr.Muhammad Ashraf | Dr. Haji Ahmad | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2001Dissertation note: The experiment was designed to study the effect of coccidiosis vaccine in comparasion with chemo-prophylactic and therapeutic measures against coccidiosis and their effect on weight gain, mortality and blood parameters in broiler breeder birds. For this purpose one hundred and twenty day-old broiler breeder chicks were obtained from local market and reared in the Experimental room of the Medicine Section, College of Veterinary Sciences (CVS), Lahore under standard managemental conditions upto 49 days of age. The birds were fed on commercial coccidiostat free feed purchased from the market The following materials (vaccines, medicine, caeca) were used
1. Local vaccine (Eimeria vaccine) was obtained from Parasitology Laboratory, CVS., Lahore.
2. Imported vaccine (Immucox; Vetec Laboratories, Canada) was purchased from the market.
3. Amprolium 60% was purchased from Grace Pharma, Lahore.
4. The infected caeca of broiler chicks was obtained from different farms and diagnostic laboratories.
One hundred and twenty day-old broiler breeder birds were divided into eight groups comprising of 15 birds in each group. Different groups were arranged according to the following pattern:
Group A. was non-infected control group, group-B was infected control group. Infection was given on day 22, group-C was vaccinated infected group. Local vaccine was given on 3rd and 10th day of age followed by the dose of 30,000 sporulated oocyst at 22nd day of age. Group-D was vaccinated with local vaccine (non infected). Group-E was vaccinated infected group. Imported vaccine was given at 7th day followed by infection at 22nd day. Group-F was vaccinated with imported coccidial vaccine, non-infected group. Group-G was infected and treated group. Infection was given on day 22 of age and the birds will be treated with Amprolium 60% at the dose of lg/2 litre of drinking water for 5 consecutive days. Group-H was non-Infected, treated with Amprolium 60% at the dose of lg/2 litre of drinking water for 5 consecutive days.
The weight of birds was weekly recorded starting from day one upto the end (42nd day) of the experiment. Faecal examination for the counting of oocyst per gram of faeces were recorded after every 4th day of the administration of infection.
It was observed that the performance of the birds of group D (noninfected, vaccinated with local vaccine) was the best as compared to all other experimental groups. However, group E (infected, vaccinated with Imported coccidial vaccine) was also given good performance.
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71.
Prevalence And Treatment Trials Against Gastrodiscus Infestation And Its Effect On Various Blood Components In Horses
by Muhammad Ali | Prof. Dr. khalid pervez | Dr. kamran ashraf | Dr. muhammad | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2005Dissertation note: This study was conducted to work out the prevalence of gastrodiscus infection in Lahore area and to check the comparative efficacy of one patent (Albandazole) and two Herbal Drugs i.e. Melia Azadarch Linn (Neem) and Nigella Sativa (Kalonji) against Gastrodiscus infection in Horses and its effect on various blood components including Hb, TLC, and DLC the purpose of this experiment was tomention extensive Pharmacological Experimentation on indigenous drug which result in the discovery of some potent Anthelmintic Drugs which would be a break through in limiting Gastrodiscus infection in horses. Furthermore, it could contribute to the improvement of our economy by making an industrial use of these resources and by saving foreign exchange via exporting these medicines abroad. In addition to these, studies were expected to contribute to the rationalization of Eastern / Unani system of Medicine, practiced by HKIMS and SIANAS.
To accomplish the study six hundred faecal samples of horses were collected and coprologically examined by fresh smear method to determine 40 naturally infected horses by Gastrodiscus infection.
The 40 infected animals were divided into four groups i.e. group A, group B, group C, and group D comprising 10 animals. Each groups A, B and C were treated with Albandazole, Melia Azadarch Linn (Neem) and Kalonji, respectively were as group D was control and remain untreated. The prevalence of Gastrodiscus infection at Lahore areas was found to be 6.6%.
The Egg per gram (EPG) counts was estimated by using Macmaster technique at zero day (pre-medication), 3rd day, 7th day and 10th day (post-medication). Groups A, B and C were treated with Albandazole, Neem and Kalonji seeds dose rate of 10ml/10kg body weight, 500 mg/kg body weight and 1gm/kg body weight, respectively.
After medication at 3rd, 7th and 10th day EPG count was measured. It was observed that at 3rd day, Albandazole Neem and Kalonji showed the efficacy 50%, 4769% and 9.09% respectively.
At 7th day, the efficacy of albandazole neem and kalonji was found to be 66.66%, 53.84%, 20% respectively.
At 10th day, the efficacy of albandazole Neem and Kalonji was found to be 95%, 60% and 27.27, respectively.
The average efficacy of Albandazole Neem and Kalonji was found to be 70.5%, 53.6% and 18.78%, respectively.
Hence, Albandazole, and Neem showed better results as compared to Kalonji. It was concluded that Albandazole and Neem were safe against Gastrodiscus in Horses.
HAEMATOLOGY
In the present study forty blood samples from naturally infected horses with different intensities of infection were examined for haematological studies to know the changes in the blood picture due to Gastrodiscus. The blood samples were collected premedication i.e. on Zero day and then on 3rd, 7th and 10th day post-medication.
A marked decrease in haemoglobin was observed after the study of infected animals on Zero day. The normal haemoglobin value was 10.5 to 15.5 g/dl. This value became near to normal on 7th day post-medication and went on increasing upto 10th day as the ova count in the faeces was decreasing.
The study regarding the total leukocytic count concluded a mild increase values of TLC, but after treatment these values decrease to normal level as the ova count in the faeces was decreasing.
The haematological finding of the present study are in complete accordance with the results of Chaudhry et al., (1991) and Peal et al. (1989). The reported that there was decrease in hemoglobin values of infected animals as compared to healthy animals. It is tempting to speculate that the decrease in haematological values may be due to the blood sucking habit of the parasite.
Availability: Items available for loan: UVAS Library [Call number: 0851,T] (1).
72.
Prevalence Of Brucellosis In Breeding And Game Horses In Lahore Division
by Syed Muhammad Jaafar Fayyaz | Dr. Khalid Pervez | Dr. Azhar | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2004Dissertation note: Sero-prevalence of brucellosis in 400 breeding and game horses from various sources in Lahore Division was analysed. Two serological tests namely Rose bengal plate and standard tube agglutination tests were employed. The Rose bengal plate test served for initial screening and the sera declared positive by Rose bengal plate test were further analysed through standard tube agglutination test, which served for quantitation of Brucella antibodies. A higher incidence of disease prevalence was recorded through Rose bengal plate test than standard tube agglutination test. The overall prevalence of the disease investigated by Rose bengal plate test was 2.5% and with the standard tube agglutination test was 0.25% in horses. The male horses had a prevalence of 0.74% by the Rose bengal plate test, female horses demonstrated a prevalence of 6.15% by Rose bengal plate test and 0.76% by standard tube agglutination test. The higher prevalence of disease was observed in female horses. While interpreting the age group relationship of the disease. It was found that adult and old animals had a higher prevalence than the young animals. The horses over 10 years of age exhibited 7.95% disease incidence by Rose bengal plate test and 1.13% by standard tube agglutination test. Only 1.54% disease prevalence was investigated in horses below 10 years of age by Rose bengal plate test. Sero prevalence of brucellosis was only detected in horses recruited from Race Cource and Phool Nagar, whereas sera of all the horses belonging to Army, Police, Rangers, Race Club and Aitchison College was negative to brucellosis. It may be due to good management of horses, good nutrition, lack of stress and no contact with cattle. The sera with SAT titre of 1:40, were considered positive while the sera showing titre of 1:20 were declared doubtful. There is need to adopt an eradication programme for brucellosis especially because of its zoonotic importance and a continuous threat to livestock industry in the shape of heavy economic losses.
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73.
Comparative Effect Of Zinc Bacitrcing And Propionic Acid On The Performance Of Broiler Chicken
by Nadeem Akram | Dr. Muhammad Sarwar Khan | Dr. Anjum | Dr. Muhammad Athar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2003Dissertation note: The idea of the study was to replace feed additive antibiotics with organic acids. Therefore diets supplemented with different levels of propionic acid were compared with diet supplemented with feed additive antibiotic zinc bacitracin in order to determine their effects on the performance of broiler birds.
One hundred day-old chicks were selected for the experiment and arranged into five groups A, B, C, D and E. There were 20 chicks in each group. Group A served as a control while the diets of group B, C and D were supplemented with 0.4%, 0.6% and 0.8 % propionic acid. The diet of group E was supplemented with feed additive antibiotic zinc bacitracin. The parameters selected for the experiment were Feed consumption, Weight gain, Feed conversion efficiency, Morbidity and mortality and Economical analysis of various treatment groups. The experiment was conducted at Animal Nutrition Section of University of Veterinary and Animal Sciences, Lahore.
The results thus obtained were statistically analyzed. Statistical analysis revealed a significant difference between group A (control) and group C (supplemented with 0.6% Propionic acid) in case of feed consumed and weight gained. There was no significant difference between various treatment groups in terms of feed conversion efficiency. As far as economics is concerned group E (supplemented with zinc bacitracin) was the most economical group among the various treatment groups. The use of propionic acid proved costly as compared to feed additive antibiotic zinc bacitracin.
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74.
Clinico Epidemiological Study Of Bacterial Causes Of Respiratory Syndrome In Cattle And Buffalo Around Lahore
by Ahtasham-ur-Rehman | Prof. Dr. Khalid Pervaiz | Dr. Muhammad Sarwar Khan | Prof. Dr | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Nature of contents: ; Literary form: Publisher: 2009Dissertation note: The present study was undertaken to determine the bacterial agents associated with respiratory tract infections in cattle and buffalo. For this purpose 100 clinically sick cattle and 100 clinically sick buffalo of both sex and age were examined. The samples were taken randomly from the Outdoor Hospital of University of Veterinary and Animal Sciences. Lahore. various District Veterinary Hospitals of Lahore and Private Veterinary Clinics of Lahore during September 2004 to February 2005.
All the animals presented during the above mentioned period were clinically examined. Those showing signs of cough and nasal discharge were clinically examined, and their respiration rate, pulse rate, temperature and lung auscultation was performed. The frequency of clinical signs were observed and found it as, abnormal lung sounds 36.5%, Nasal discharge 69%, Cough 73%, Anorexia 93.5%, Depression 90.5%, Dyspnea
28%, Fever 84.5%, Increased pulse rate 66%, Increased respiratory rate 76.5%, Increased breath sounds 64.5% and Loud breath sounds 56%.Whereas no above mentioned signs were observed in control group.
A total of 200 samples of nasal mucus were collected from 100 clinically sick cattle and l00 clinically sick buffalo. Nasal swabs were collected from clinically sick animals. Nasal swabs collected from the nasal cavity of the affected animals, in gamma sterilized cultural swabs, were properly labeled and kept at 4°C till further processing. Each affected animal was also tested For Bovine Tuberculosis using Single Intradermal Test. Smears were made from each nasal swab, stained with Gram's staining and was examined for the presence or absence of bacteria. Each positive bacterial swab was inoculated in nutrient broth, tubes, which was incubated at 37°C and then examined after
different intervals of time for turbidity. A loopful of material from positive turbid broth was streaked on the nutrient agar and incubated at 37°C for 24 hours. Different types of colonies were purified. Smears were prepared from each type of colony, stained with Gram's staining and examined under oil immersion lens. The staining and morphological characteristics were recorded. Out of total 200 samples, only 152 were positive for bacterial contamination. The prevalence so calculated was 76% amongst the animal examined. A total number of I 52 isolates belonging to the genera Pasteurella, Streptococcus. Staphylococcus. Escherichia and Mycobacteriurn were isolated and identified on the basis of morphological, staining, cultural and biochemical characters of the organisms isolated from nasal mucus of cattle and bLiffalo. Of these Pasteurella haemolytica was isolated from 43 (21 .5%), Pasteurella multocida 3 I (I 5.5%), Escherichia coli 11 (5.5%), Streptococcus 29 (14.5%), Staphylococcus 23 (11.5%) and Mycobacteriurn bovis 15 (7.5%).
The main objective of this study was to assess and record the incidence of various bovine respiratory tract infections and to study the bacterial etiological agents involved in the production of respiratory tract syndrome. The etiological agents were identified by cultural and biochemical characteristics of isolates. These findings will help in devising proper and early measures required to cure the disease and to boost LI the prodLictive performance of these ruminants.
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75.
Effect Of Dose And Route Of Ivermectin On Lice Infested Domestic Pigeons
by Assad Ullah | Dr. Muhammad Sarwar Khan | Dr. Azhar | Dr. Jawaria Ali Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2005Dissertation note: The present project was designed to study the prevalence of lice infestation in pigeons and to study the efficacy of Ivermectin against lice infestation in pigeons.
A total of 300 pigeons were examined to study the prevalence of lice infestation in domestic pigeons in different localities of Lahore (pigeon owners and aviaries) during the month of April, 2004. Out of 300 birds examined 271 birds revealed lice with an overall incidence of 90.33% of lice infestation.
Permanent mounts were prepared from specimens collected from different birds. On the basis of morphological characters and taxonomical features the specie of lice identified was Columbicola columbae (Slender Pigeon Louse).
The efficacy of Ivermectin was determined on the basis of reduced number of lice from the body of pigeons in group A, B and C, group D served as untreated infested control and group E served as healthy control group. Birds were examined on days zero, 3, 7 and 10 of the experiment. On day 10, efficacy of Ivermectin was 91.66%, 75% and 83.33% in group A, B and C respectively.
Haematological examinations were made to compare the blood picture of infested birds treated with Ivermectin , infested birds kept as control and healthy control birds. Blood parameters studied were: Haemoglobin Estimation and Differential Leukocytic Count. The results of haematological examination showed a significant increase in haemoglobin level of birds treated with Ivermectin, there was a significant decrease in differential leukocytic count of treated birds.
The values thus recorded were analyzed statistically using computer program MSTAT.
The present project was designed to study the prevalence of lice infestation in pigeons and to study the efficacy of Ivermectin against lice infestation in pigeons.
A total of 300 pigeons were examined to study the prevalence of lice infestation in domestic pigeons in different localities of Lahore (pigeon owners and aviaries) during the month of April, 2004. Out of 300 birds examined 271 birds revealed lice with an overall incidence of 90.33% of lice infestation.
Permanent mounts were prepared from specimens collected from different birds. On the basis of morphological characters and taxonomical features the specie of lice identified was Columbicola columbae (Slender Pigeon Louse).
The efficacy of Ivermectin was determined on the basis of reduced number of lice from the body of pigeons in group A, B and C, group D served as untreated infested control and group E served as healthy control group. Birds were examined on days zero, 3, 7 and 10 of the experiment. On day 10, efficacy of Ivermectin was 91.66%, 75% and 83.33% in group A, B and C respectively.
Haematological examinations were made to compare the blood picture of infested birds treated with Ivermectin , infested birds kept as control and healthy control birds. Blood parameters studied were: Haemoglobin Estimation and Differential Leukocytic Count. The results of haematological examination showed a significant increase in haemoglobin level of birds treated with Ivermectin, there was a significant decrease in differential leukocytic count of treated birds.
The values thus recorded were analyzed statistically using computer program MSTAT.
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76.
Clinicotherapeutic And Haematological Studies Of Coccidiosis In Qualis
by Muhammad Zahir Iqbal | Prof. Dr. Khalid Pervez | Dr. Kamran | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2005Dissertation note: The study was designed to compare the efficacy of different anticoccidials i.e. Coxigon and Toltrazuril and their effect on blood values in quails. A total of 100 young healthy quails were purchased and raised for a week in good husbandry and hygienic conditions. The birds were randomly divided into four groups i.e. A, B, C and D, comprising of 25 birds each. Group A was treated with Toltrazuril, while group B was treated Coxigon. Group C was infected, non medicated and group D was uninfected control group. All the groups except D were given primary challenge doses of infection. The oocysts count was done on day zero, 3, 5 and 7. Record of mortality, morbidity was kept and postmortem of dead birds was also performed. The data collected was subjected to statistical analysis using one way analysis of variance and least significant difference (LSD) test, to detect the differences between the treatments and means. It is concluded that Toltrazuril as anti-coccidial revealed significant (P<0.05) difference among all the treatments in terms of weight gain, feed efficiency, oocyst count, reduction and decrease in mortality ratio and help a lot to normalize the blood values of quails. The results of other anti-coccidial i.e. Coxigon was not satisfactory, due to less decrease in mortality ratio, feed intake and weight gain and help little to normalize their blood values, and group C was infected non medicated showed great mortality and morbidity rate as compared to other groups. The results of this study will help to the Feed Farmers in choosing the best anti-coccidial drug, while the farmers will get choice amongst anti-coccidial drugs.
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77.
Prevalence Of Ecto And Endo Parasites In Cross Bred Cattle At Lahore And Its Chemotherapy With Ivermectin
by Saleem Khan Niazi | Dr. Muhammad Sarwar Khan | Dr. Azhar | Prof. Dr. Khalid Pervez | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2003Dissertation note: The present project had been designed to study the prevalence of Ecto and Endo parasites in crossbred cattle of all age groups and to test the efficacy of ivermectin (Ivergen-Symans) at recommended
dose rate by the company against ecto and endo parasites in naturally infected cross bred cattle. For this project 400 crossbred
cattle were scanned to isolate 60 infected animals.
These 60 animals were divided in to 3 main groups i.e. A, B, and C, comprising 20 animals each. Each main group was subdivided into four sub groups, comprising 5 animals each and were marked as Al, A2, A3, & A4, Bi, B2, B3, B4 and Cl, C2, C3 & C4.
Out of total 400 animals, which were scanned 278 (69%) animals were found positive having ecto- endo- and mixed parasitic infection. Faecal samples of all 400 animals were tested for GIT nematodes, out of which 158 (40%) animals were found positive, skin scrappings of all 400 animals were tested for ecto-parasites, out of which 68 (17%) animals were found positive. 52 (13%) animals were found positive for mixed infection of both ecto- and endo-parasites.
The results of the present study revealed that Ivergen is highly effective at extremely low dosage against wide variety of nematodes and arthropods parasite, so it is recommended for field use.
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78.
Comparative Efficacy Of Various Drugs Against Git Nematodes And Their Effect On Blood Parameters In Sheep And Goats
by Naseeb Ullah | Prof. Dr. Khalid Pervez | Dr. Kamran | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2004Dissertation note: The present project was designed to study the comparative efficacy of various drugs; 1) Albendazole (Farbenda), 2) Oxfendazole (Oxafax) and 3) Karanjwa (Caesalpenia crista) against naturally infected GIT nematodes in sheep and goats under field condition in and around district Kohlu, Balochistan and to find out their effect on some blood parameters; 1) Haemoglobin, 2) Total leukocyte count and 3) Differential leukocyte count and to detect the prevalence
For this purpose 180 sheep and goats naturally infected coprologically were examined. Out of 180 sheep and goats 106 were found positive showed 58% prevalence. For the treatment protocol, forty naturally infected and ten non-infected were selected and divided randomly into five groups having ten sheep and goats in each group viz A, B, C, E and D. Group A was treated with Albendazole 1ml/20mg body weight. Group B was treated with Oxfendazole 1ml/5kg body weight. Group C was treated with Karanjwa (Caesalpenia crista) @ 2mg/kg body weight. Group E was kept infected non-medicated control group. Group D was kept non-infected non-medicated control group.
In group A the eggs per gram of faeces were 22,700 on day zero and no eggs were found on day 7th which was treated with Albendazole. It has been observed from the result that Albendazole showed 100% efficacy on day 7th. In group B which was treated with Oxfendazole with egg per gram of faeces were 23,200 on day zero 22,800 on day 7th and no egg were found on day 14th. It has been observed from above results that the Oxfendazole shown 95% efficacy on day 7th and 100% efficacy on day 14th. In group C which was treated with Karanjwa, the eggs per gram faeces were 19,500 on day zero 22,100, on day 7th 31,800 on day 28th. Group E which was kept infected non-medicated control group, the egg per gram were found on day zero, 7th, 14th, 21st and 28th, 20000, 23700, 27500, 31200 and 35300.
On the haematological study the haemoglobin and lymphocyte level were decrease as compared to non-infected control group whereas the value of leukocyte, neutrophil, monocyte and eosinophil were increased as compared to normal group. In group A and B the haemoglobin and lymphocyte value slightly increase on day 7th, 14th, 21st and 28th post-medication. Moreover, the values of leukocyte, neutrophil, monocyte, eosinophil and basophil were slightly decrease on day 7th, 14th, 21st and 28th post-medication in group A and B. It has been observed from above study that Albendazole and Oxfendazole shown their effect on blood parameters, whereas group C which was treated with Karanjwa have shown no effect on faecal egg count and blood parameters.
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79.
A Study Of Babesiosis In Calves At Livestock Experimental Station, Qadirabad And Adjacent Areas
by Nadeem Niazi | Prof. Dr. Khalid Pervez | Dr. Javed Iqbal | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2006Dissertation note: Bovine babesiosis (Piroplasmosis, Texas fever, redwater, tick fever) is a febrile, tick-borne disease of cattle, caused by one or more protozoan parasites of the genus Babesia and generally characterized by extensive erythrocytic lysis leading to anemia, icterus, hemoglobinuria, and death.
There are probably at least six Babesia species responsible for bovine babesiosis. Most can be categorized as being small or large Babesia. Morphological and serological differences are used to distinguish the different species. The two that are of most concern in our country are Babesia bigemina and Babesia bovis which are inflecting considerable losses to the livestock especially cattle.
The present study was conducted to find out the prevalence of babesiosis in cow calves at livestock experimental station Qadir Abad and adjacent areas of District Sahiwal and to find out the comparative efficacy of two babesicidal drugs i.e Fa-try-banil (diminazene aceturate) Prix Pharmaceutica. Lahore, Pakistan and Imizol (Tmidocarb dipropionate) ICI, Pakistan. In this study effect of babesiosis on different blood parameters i.e hemoglobin estimation and total ervthrocytic count was also studied.
For this purpose 415 calves were examined for the presence of babesiosis. Out of these 30 calves were found positive showing 7.2 percent prevalence. For treatment purpose 40 calves were selected randomly i.e. 30 infected and 10 healthy. i'hcse were divided into 4 groups A, B, C and D comprising 10 animals each. Diagnosis was confirmed on the basis of blood smear method. The animals of group A were treated with Fa-try-banil (dirninazene aceturate) @ 3.5 mg/kg body weight intramuscularly at day zero.
Four out of 10 calves recovered at 3" of injection, one calf recovered 7 day of 1S' injection, 4 calves recovered at 10th day of injection. This drug showed 90% efficacy while the calves of group B were treated with Imizol (Imidocarb dipropionate) lml/l00 kg body weight at day zero. Seven out of 10 calves recovered at 3rd day of injection, two recovered at 7 day of injection and remaining recovered at l0" day of 1S1 injection. This drug showed 100 percent efficacy at 10th day. Animals of group C served as infected untreated control and group D served as healthy non-infected control. Comparative efficacy of both the drugs was determined on the basis of disappearance of clinical signs and babesia from the blood. No side effects of the drugs were noted.
Haematological examination revealed a significant decrease in haemoglobin concentration and total erythrocytic count pre-medication. It has been observed from the present study that Imizol was the drug of choice for the treatment of babesjosis in calves.
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80.
Comparative Study Of Flank Vs Midline Approach For Overiohysterectomy In Cats
by Mudassir Ahmad Rana | Dr. Muhammad Arif Khan | Dr. Asim Khalid Mehmood | Prof. Dr. Nasim | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Nature of contents: ; Literary form: Publisher: 2005Dissertation note: Ovariohysterctomy is one of the most commonly performed operation in cats and is indicated for both medical and behavioral reasons. The most common indication of ovariohysterectomy is elective sterilization which avoids all objectionable sexual behaviors and over population. Ovariohysterectomy is the treatment of choice for most uterine diseases and it greatly reduces risk of mammary neoplasia. The method of performing ovariohysterectomy in cats must be affordable, safe, reliable & convenient. In the past different approaches have been tried for ovariohysterctomy in cats viz. linea alba(ventral midline) and vertical flank. But the relative efficacy of the approaches has not been determined in the past in our conditions. The objective of our study is to compare and evaluate these two approaches in our environmental conditions. The Flank approach was found to be relatively better than the Ventral midline approach in our conditions in terms of convenience, reliability, safety with rapid recovery and less postoperative complications.
Availability: Items available for loan: UVAS Library [Call number: 0917,T] (1).
81.
Sero-Epidemiological And Haematological Studies On Toxoplasmosis In Cats, Dogs And Their Owners in Lahore
by Azeem Shahzad | Dr. Muhammad Sarwar Khan | Mr. Kamran | Prof. Dr. Khalid Pervez | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2005Dissertation note: Toxoplasmosis is a parasitic zoonosis with worldwide distribution, caused by Toxop1asna gondii and is very common in cats, dogs and human. Keeping in view the zoonotic importance of the disease, the current study was conducted to find out the epidemiological status of toxoplasmosis in cat, dog and human population in Lahore city and to determine the possibility of transmission of toxoplasmosis from cats and dogs to their owners. For this purpose serum samples from cats (ii=25 domestic, n=25 stray) dogs (n=50 domestic, n=50 stray) and human (n=25 cat owners, n=50 dog owners, ii=50 people having no contact with cats and dogs, ii=25 UVAS, Employees) were collected and analyzed by using Latex Agglutination Test (LAT) to find out the prevalence of toxoplasmosis in cat, dog and human population.
Overall 56% cats were seropositive for anti-toxoplasma antibodies. Stray cats had the high prevalence (64%) followed by domestic cats (48%). Overall, 53%, 25%, 10.7%, 10.7% cats were seropositive at screening dilution of 1:16, 1:64, I : 128 and 1:256, respectively. The highest prevalence (71%) was detected in cat in the 7 year or above age group. Neither of the positive rates was found to be different between male (56.5%) and female (55.5%). The sero-positivity percentage of toxoplasmosis was highest in local breeds of the cats (64%) followed by Himalayan and Persian (50%) and Siamese breed of cat (46%). Furthermore the domestic cats, which had wandering habits, had higher seropositivity (62%) than the cats, which had not these habits (41%). The prevalence of toxoplasmosis was high in the cats receiving raw meat (66%) however the prevalence in the cats receiving commercial cat food and kitchen prepared/left over human food was 40% and 44.4%, respectively.
Overall 39% dogs were sero-positive for anti-toxoplasma antibodies. Stray dogs had the high prevalence (50%) than the domestic dogs (28%). Overall 46%, 28.2%, 15.3% and 10.2 % dogs were sero-positive at screening dilution of 1:16, 1:64, 1:128 and 1:256, respectively. The highest prevalence of toxoplasmosis (45.9%) was recorded in dogs of age group of >1-3 years. Neither of the positive rates was found to be different between male (35.4%) and female (35.4%). The sero-positivity percentage was highest in local breeds of dogs (50%) followed by German Shepherd (42%), Bulldog , Labrador Retriever and Russian (33%), English Pointer (30%), Alsatian, Bull Terrier and German Pointer (25%) and Greyhound (20%). Dogs having access to house as well as yard has the highest prevalence (40%) following the dogs having access only to yard (25%) and the dogs kept strictly at homes had the lowest prevalence (16%). Dogs fed raw meat had a relatively high prevalence of toxoplasmosis (40%) than the dogs fed commercial dog food and home cooked food had prevalence of 18.7% and 2 1.4%, respectively. Overall 22% human were sero-positive for anti-toxoplasma antibodies. The highest seropositivity was observed in cat owners (3 2%) followed by dog owners (26%), UVAS, employees (20%) and the lowest sero-positivity (14%) was observed in people having no contact with dogs and cats. Overall 63.6%, 27.2%, 3.0% and 6.0% human were seropositive at screening dilution of
1: 16, 1:64, 1: 128 and 1:256, respectively. The highest prevalence of toxoplasmosis (26%) was observed in people of 30-40 years or above age group. Neither of the positive rates was found to be different between male (21.9%) and female
(22.2%).
There was decrease in haemoglobin level of cats, dogs and human positive for anti-toxoplasma antibodies. There was significant decrease in total leukocytic count of cats, dogs and human positive for anti-toxoplasma antibodies. Nutroplielia, lymphocytopenia, cosinopenia and monocytopenia was observed in cats, dogs and human positive for anti-toxoplasma antibodies.
Availability: Items available for loan: UVAS Library [Call number: 0920,T] (1).
82.
Comparative Therapeutic Trials Against Coccidiosis In Dogs
by Maryam Nisar | Dr. Jawaria Ali Khan | Dr. Muhammad Sarwar Khan | Prof. Dr. Haji | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2005Dissertation note: The present project was designed to find out the prevalence of coccidiosis (Isosporiosis), to evaluate the comparative efficacy of Co-trimoxazole &Furazolidone and to study the effect of Isosporiosis on blood parameters.
For this purpose the faecal samples of two hundred dogs were examined in the Medicine laboratory, University of Veterinary and Animal Science, Lahore by direct smear method, and also concentration technique for identification of Isospora oocyst. Out of two hundred dogs thirty-six were found positive for the coccidial infection, showing the prevalence of Isosporiosis as 18%. For chemotherapeutic trials, thirty naturally infected and ten non-infected dogs were selected and divided randomly into four groups having ten dogs in each groups viz A, B, C and D. Group A was treated with Co-trirnoxazole at the dose rate of 15mg/kg (orally) and group B was treated with Furazolidone at the dose rate of 8mg/kg (orally). Group C was kept as infected non-medicated control. Group D was kept as non-infected and non-medicated control.
Faecal samples of experimental dogs were examined for OPG counts on day zero (pre-medication), 3rd, 7th and 10th day of medication and percentage reduction of oocyst was calculated. Cotrirnoxazole showed 63%, 90%and 97% efficacy whereas Furazolidone showed 63%, 89.8%and 95% efficacy on day 3, 7 and 10, respectively.
Statistical analysis of data revealed non-significant difference (P>0.05) between the groups A, B and D (-ye control) on day 7 and 10 of treatment. Based on criteria of percentage reduction in the number of oocyst in faeces, it was observed that Co-trimoxazole was the most effective (97%) followed by Furazolidone (95%) against Isosporiosis in dogs.
Haematological study revealed that the values of haemoglobin and packed cell volume were lower in groups A, B, and C as compared to non-infected control group. Whereas as a result of treatment in-group A and B the values of haemoglobin and packed cell volume gradually increased on day 3, 7 and 10 post-medication. It has been observed during the present study that Cotrimoxazole and Furazolidone showed their effect on blood parameters as a result of curing Isosporiosis.
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83.
Prevalence And Chemotherapy Of Balantidium Coli In Cattle Around River Ravi Bank Lahore
by Ch. Qasim Bilal | Prof. Dr. Khalid Pervez | Dr. Muhammad Sarwar Khan | Prof. Dr. Haji | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2006Dissertation note: The present project was designed to find out the prevalence of Balantidium coli and to evaluate the efficacy of Terramycin, Dysen forte, Flagyl against naturally occurring balantidosis in cattle under field conditions around the river Ravi bank Lahore. The faecal samples from animals were collected directly from rectum of animals and brought to the laboratory of Department of Clinical Medicine and Surgery, University of Veterinary and Animal Sciences, Lahore for coprological examination.
For this purpose two hundred cattle were examined coprologicaly around the bank of river Ravi in Lahore. Out of 200 cattle, 50 were positive, so the prevalence of Balantidium coli in cattle was 25%. Out of 50 positive animals thirty two cattle having balantidiosis were selected for chemotherapeutic trials and eight non effected cattle were selected and divided into five groups viz. A, B, C, D and E comprising eight animals each. The animals of Group-A were treated with oxytetracycline capsules (Terramycin) @ 8mg/kg orally, Group-B with secnidazole tablets (Dysen forte) @ 10mg/kg orally, Group-C with metronidazole tablets (flagyl) @ 25mg/kg orally. The animals in Group-D were serving as infected untreated control group and Group- E were serving as untreated healthy control.
The efficacy of drugs was evaluated on the basis of disappearance of clinical signs and by reduction in number of cysts/trophozoites on zero, 3, 7 and 1 0 day post medication. Efficacy of oxytetracycline (terramycin) was 25%, 50% and 62.5% on 3, 7 and 10 day, respectively. Efficacy of secnidazolc (dysen forte) was 37.5%, 75% and 87.5% on 3, 7 and 10 day, respectively. Efficacy of metronidazole (flagy) was 12.5%, 25% and 37.5% on 3, 7 and 10 day, respectively.
It was concluded from the above results that Dysen Forte was more effective than Terrarnycin or Flagyl. However, Terramycin showed better efficacy than that of Flagyl.
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84.
Prevalence And Chemotherapy Of Helminthases In Parrots At Lahore Zoo.
by Ashgar Khan | Prof. Dr. Muhammad Sarwar Khan | Prof. Dr. Haji | Prof. Dr. Khalid Pervaiz | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2007Dissertation note: The study was conducted to determine the incidence of helminthiasis in all breeds of parrots and to evaluate the comparative efficacy of two different broad spectrum anthelmintics, albendazole (Farbenda, Farvet) and levamisole (Nilverm drench, ICI) used against the nematodes at Lahore Zoo. For this purpose, 130 Faecal samples were collected group wise in clean polythene bags, properly labeled for identification and examined for the identification of helminths. Eighty eight out of 130 were positive for single or mixed infection of Heterakis gallinae and Ascardia gaul have individual percentage as 73.86% and 26.14% respectively.
Of 88 positive birds belonging to different breeds of parrots, 72 of the same age, weight and number were devided in three equal groups (24 each) i.e. A (love birds peach face breed), B (budgerigar ring necked breed), and C (Alexandrine parrots, Blossom headed parakeet and Blue fronted amazon breeds), while in group D (Cockatiel, Blue ring necked parakeet, Eclectus parrot and African grey parrot breeds), only uninfected and untreated birds were kept.
Drug therapy was only induced to the group A i.e. albendazole (Farbenda, Farvet) @ 0.lml/kg body weight and group B (levemisole hcl (Nilverm, ICI) @ 5m1/litre of water, while infected but non treated birds were placed in group C.
Faccal samples of experimental birds were examined for counting of egg/gram of faeces on day"O" (pre-medication) with McMaster egg counting technique (Soulsby, 1982).
Faecal egg counts were again carried out on day 3, 7 and 10 of medication and percentage reduction of EPG calculated. The overall prevalence of gastro intestinal helminthes in different breeds of parrots was found as 67.69%.
Albendazole was found to be the more effective (96.33%) among the two anthelmintics while levamisole was less effective (84.90%). The EPG rise up to 8.98% at day 10 post medication in untreated group C was noted while no infection was observed in group D through out the experimental study.
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85.
Diagnosis And Therapeutic Trials On Cryptosporidium Parvum In Dairy Calves
by Amar Nasir | Dr. Muhammad Avais | Prof. Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
drama
Publisher: 2008Dissertation note: Cryptosporidium parvum is a coccidian agent of diarrhoeal disease affecting many mammals, including dairy calves. Calves infected with this enteropathogen may either be asymptomatic or manifest mild to profuse diarrhoea and dehydration. Keeping in view the importance of Cryptosporidium parvum in dairy calves, the current study was conducted to find out the prevalence in dairy calves, in and around Lahore and also to find out the most effective therapeutic measure to control the infection. For this purpose, 500 faecal samples (n=250 cow calves, n=250 buffalo calves) from different dairy farms and home-bred dairy calves were collected and analyzed by using faecal floatation method and modified Ziehl-Neelsen staining technique. Overall, 25.6% Calves were shedding C. parvum with a slightly high infection rate in the cow calves 27.2% than buffalo calves 24%. The highest infection rate was recorded in 1-30 days age group of dairy calves as 50.81% and 42.02% in the cow calves and buffalo calves, respectively. The infection rate of C. parvunm in the dairy calves of cow breeds indicated relatively high infection rate in crossbred cow calves (28.18%) than the Sahiwal cow calves (20%) and Nih Ravi buffalo calves (24%). The pattern of oocyst shedding was negatively correlated with increase in age, highest in the 1-30 days age group and lowest in the age group ranging from 9 months to 1 year and above. Diarrhoeac calves were infected significantly higher than the nondiarrhoeac calves indicating a direct relationship of diarrhea with C. parvum infection. Diarrhoea was the highest contributing factor to infection in 1-30 days age group with 58.97% infection rate in both the cow calves and 48.88% in buffalo calves than the nondiarrhoeac calves of the same age group as 36.36% and 29.16%, respectively. The infection rate was not associated with the sex of the dairy calves and the infection rate was almost equal in both the sexes. The cumulative rate of infection was relatively high (30.28%) in the physically healthy calves than weak (21.5%) and emaciated (19%) calves. Milk suckling calves were infected almost two times more than the ones utilizing both milk and fodder and almost 7 times of the fodder eating calves. The calves kept on dirt yards were infected more (28%) than the ones on the paved floor (21 .11%). A significantly high infection rate was observed in the cow calves and buffalo calves having some sort of contact with birds, rodents, dogs and cats (31.3%) and (25.80%) respectively, than the calves having very little or no contact with birds, rodents, dogs and cats as 19.27% and 12.12% in cow calve and buffalo calves, respectively. The results of the comparative efficacy of a.zithromycin and cotrimoxazole and kalvangi showed that azithromycin was the most effective of the three in treatingcryptosporidial infection in dairy calves under field conditions. It resulted in significant reduction in the oocyst shedding and consequently, better weight gain compared with kalvangi and Cotrimoxazole. The efficacy of Kalvangi in weight gain compared with kalvangi and Cotrimoxazole. The efficacy of Kalvangi in weight gain may be due to its vitamins, enzymes and Nigellone and Thmoquinone acting as an immune system booster. The results of Azithromycin in the present study on the overall weight gain of calves was significantly higher than the other two drugs used in the study suggesting it as a drug of highest efficacy.
Availability: Items available for loan: UVAS Library [Call number: 0985,T] (1).
86.
Clinico -Therapeutical Trials Of Lactic Acidosis In Small Ruminants
by Haq Aman Ullah | Dr. Jawaria Ali Khan | Prof. Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2009Dissertation note: During the present study clinical examination of 200 small ruminants (sheep and goats)
any breed, age and sex with the history of diarrhea was performed at the Outdoor Hospital,
University of Veterinary and Animal sciences Lahore and adjacent areas. A total of 38 animals
were diagnosed positive for the disease. Temperature, pulse rate, respiration rate, rumen pH,
serum pH, ruminal movements and ruminal protozoa of affected animals were studied before and
after treatment with two drugs magnesium hydroxide and sodium bicarbonate.
It was found that rectal temperature, rumen pH, blood pH, ruminal movements decreased significantly in lactic acidotic sheep and goats before treatment as compared to control group. While increased pulse and respiration rate were observed in lactic acidotic group before treatment as compared to control group. Thirty diseased and ten healthy animals were divided into four groups i.e. A, B, C and D each having ten animals. Group 'A" was provided with magnesium hydroxide at a dose rate of 1.11 g/ Kg body weight orally mixed in water at a rate of 450 g/ 3.5 liter once, group "B" was treated with sodium bi carbonate at a rate of lg/ kg body weight orally once, group "C" was kept as diseased untreated control and group "D" acted as healthy control. Mean values obtained before treatment were rectal temperature 99.74 F° + 0.67153, lOO.59F° 1 0.75580, 101.25 F° ± 0.49448 and 102.86 F° ± 0.30155 for group A, B, C and D respectively. Rectal temperature values after treatment were 102.47 F° ± 0.2 1294, 101.9
+ 0.27849,
101.19 F°±0.41965 and 102.95 F° ± 0.16142 for group A, B, C and D respectively. Mean pulse rate values for group A, B, C and D before treatment were 100.6/mm ± 3.40008, 97.2/mm ± 4.24745, 103.6/min ± 2.5636 and 86.3/min ± 1.85626 respectively while after treatment were 88.55/min ± 1.77768, 92/min ± 1.75123, 94.3/min ± 1.90938, 86/min ± 1.06460 respectively. Mean respiration rate values before treatment were 24.1min ± 0.86218, 28.2/min ± 2.52020, 24/min ± 0.84329 and 19.8/min ± 0.59256 for group A, B, C and D respectively while after treatment were 20.55/min ± 0.78953, 22.8/min ± 0.80001, 24.5/min ± 0.79234 and 20.7/min ± 0.66751 respectively. Mean rumen pH values obtained before treatment were 4.43 ± 0.14533, 4.49 ± 0.13287, 4.76 + 0.17075 and 6.39 ± 0.13699 while after treatment were 5.66 ± 0.17125, 5.41 ± 0.13506, 4.94 ± 0.18683 and 6.42 ± 0.08035 for group A, B, C and D respectively. Mean d pH values obtained before treatment were 7.18 ± 0.04667, 7.1 ± 0.05375, 7.21 ± 0.05044 and 7.33 ± 0 .02808 while after treatment were 7.37 ± 0.02806, 7.25 + 0.02390, 7.18 ± 0.03837 and 7.41 + 0.0383 7 for group A, B, C and D respectively.
Ruminal protozoa were completely absent in ruminal fluid of lactic acidotic group. Ruminal stasis was also observed in lactic acidotic group.
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87.
A Study On Surveillance Of Various Diseases/Problems Of Commercial Broiler Farming In Azad Kashmir
by Shaista Fazil | Dr. Muhammad Athar Khan | Dr. S. Naeem Jafary | Miss Sameera | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2001Dissertation note: The main objective of present work was to investigate the prevalence of various diseases and target the managemental factors affecting the prevalence of various diseases in broiler farming in Azad Kashmir. For this purpose, the project was divided into three portions.
In the first portion, a data regarding the prevalence of various diseases in broiler farms was collected from 1990-2000. Maximum mortality was due to infectious bursal disease which caused mortality percentage of 15.4. Other important diseases observed were coccidiosis (12.9%), Omphalitis (8.8%), Colibacillosis (8.2%). In the second portion of the project, one year retrospective study was done. This study was conducted from December, 1999 to December 2001. During this period, twenty broiler farms were visited. These birds had housed birds from 1000 to 5000.
The information was collected from farmers, attendants and daily mortality register present at the farms. The influence of season on the prevalence of disease was also observed. A questionnaire was designed to collect the data from each farm that related to mortality rates, vaccination, susceptible age, managemental fault. Highest mortality was due to viral diseases. Infectious bursal disease was the great problem with morality percentage of 29.2 followed by Hydropericardium syndrome having mortality percentage of 20.3 and omphalitis with mortality percentage of 19.
Influence of season on the disease was observed by dividing a calendar year into two portions i.e. summer and winter and mortality due to various diseases into two seasons was compared. Early chick mortality, Gumboro disease, Newcastle disease and respiratory diseases were observed to have high incidence in winter than summer while Hydropericardium, colibacillosis and coccidiosis were common in summer than winter.
In the third portion of the project, a three months duration study period was decided from June to March, 2001. During this period, twenty broiler farms were visited and study on the prevalence of various diseases, disease mortality rates and managemental factors responsible for various diseases was done. During this period overall mortality was 15.4% due to various diseases. Important diseases causing mortality were Gumboro (25.9%), Hydropericardium (19.3%), Colibacillosis (14.5%) and Omphalitis (14%).
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88.
Investigation On Epidemiology And Economics Imporatanc Eof Major And Common Livestock Diseases In Distt. Gujrat
by Mohammad Riaz | Dr. Muhammad Sarwar Khan | Dr. Asif | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1990Dissertation note: Livestock sector has faced great set back in its development programmes because of the economic losses resulting from various animals diseases. Such losses, though highly colosol in nature, had never been determined precisely in the past, hence, it became a dire necessity, the present study aimed at estimating the losses caused by various animal diseases in District Gujrat and to find out the possible contributory factors.
An active surveillance was conducted, in Tehsil Gujrat. The data was collected by a survey on the basis of a comprehensive questionnaire through personnel interview of livestock owners at their places. The blood samples were collected of aborted animals and serum samples were submitted to College of Veterinary Sciences, Lahore, Laboratory for diagnosis of brucellosis.
In pursuance of the present study the data was analyzed statistically and the main conclusions drawn were as under. The incidence, mortality rate and fatality rate due to H.S. were in young buffalo 14.64%, 12.40% and 84.69%. In adult buffaloes were 2.36%, 1.01% and 42.79% respectively.
Diseases of various categories have been given below in order of their respective rate of mortality such as abortion 0.29% in buffalo, 0.44% in cattle and 0.08% in goat. Mastitis in buffalo 0.04%, Haeinoglobinurea in buffalo 0.46% and in cows 0.44%. Milk fever in buffalo 0.17% post parturient prolapse in buffalo 0.25%, Metritis in buffalo 0.17% and in cattle 0.22%. In case of foot and mouth disease in young buffalo incidence 5.75% and in adult 11.72%. In cattle incidence was 9.01% in young and in adult 15.11%. In case of enterotoxaeinia disease in young goat, the morbidity, mortality and fatality 0.75%, 0.75% and 100% respectively. In adult goat 10.60%, 9.83% and 92.73% respectively. In case of young sheep incidence, mortality and fatality rate were 10.08%, 9.24% and 91.66% in adult sheep 10.89%, 7.26% and 66.66% respectively.
A monetary loss of Rs.1.33 million was estimated annually in buffalo and cattle, sheep and goat, due to various diseases in surveyed area in District Gujrat.
It is evident from the informations gathered from the respondents that the livestock owners residing at distant places from a veterinary hospital may not comfortably utilize the hospital facilities.
The village ponds as the important disease spreading factor among the livestock (Nazir al. 1978) poisonous plants and entry of new animals to herd flock with out adopting precautionary measures.
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89.
The Impact Of Community Based Animal Helth Services Delivery System On Epidemiological Parameters And Farmer'S
by Farrukh nazir | Dr. Muhammad athar khan | Dr. Haji ahmad hashmi | Dr. Muhammad.
Material type: ; Format:
print
Publisher: 2006Dissertation note: A study was conducted to understand the impact of community based animal health services delivery systems on epidemiological parameters and farmer's economic sustainability in Central Punjab. In Pakistan three systems for the animal health services delivery are being practiced without any data base and conclusive findings for the comparison purposes and in terms of the replication if needed in future, therefore, a study was planned to quantify and compare the three systems. These systems are; community based, public based and conventional based animal health services delivery systems. As the community based system was launched as Halla scheme, in Central Punjab through the German Technical Cooperation program / funding. Therefore, the other two systems i.e. public and conventional based were selected in the areas adjacent to the community based system (Halla Cluster). The project area was selected because of the similar geographical, environmental, socio cultural and political similarities. One cluster of five villages was selected randomly for each system. The data was obtained from each cluster through active disease surveillance and was recorded on a questionnaire. Each questionnaire was used for one farmer. The cluster of five villages was 'considered as one herd. In the 1st project, the clusters were quantified and compared on different parameters, like provision of animal health services, provided from the system to the member farmers. Epidemiological parameters like morbidity and mortality rate were recorded and analyzed statistically. In the 2IId project, the community trials were also conducted to compare the efficacy of prophylactic interventions, for the economically important diseases of buffaloes and cattle i.e. the haemorrhagic septicaemia and foot and mouth disease. The effect of deworming was also recorded with reference to morbidity and mortality. In the third project the sustainability of the farmers residing in the systems were compared in terms of cost benefit ratio. Animal health services were arranged like vaccination, treatment, deworming, artificial insemination and nutrition support. Poor, good and better services were provided in conventional based, community based and public based animal health services delivery systems, respectively. The impact of services on morbidity and mortality was recorded, the minimum morbidity and mortality rate was recorded in the community based system and moderate and maximum morbidity rate, mortality rate, number of outbreaks and fertility rate due to various diseases were recorded in the conventional based animal health service delivery system. The results were statistically analyzed and significant difference at a level 5% was estimated. The efficacy of the vaccination was estimated and it was statistically found that the morbidity and mortality rates were significantly low in the intervention herds of buffaloes and cattle, as compared to non intervention herds. The overall sustainability of the farmer in term of cost benefit ratio was higher in community based as compared to public based and conventional based animal health services delivery system. In conclusion the better the animal health services delivery system, the more prosperous was the farmer. So, it is recommended that the community based animal health service system be promoted and replicated on priority basis. The animal health services are provided by public based service deliverers but they are not of the same quality as were provided by the community based system in Halla Cluster. This is the reason that in spite of all the services provided by the public based system, the morbidity rate and mortality rate due to various infectious and non infectious diseases were higher in buffaloes and cattle as compared to the community based system. In conventional based system neither the community based services nor the public based services were available for the farmers because those areas were remote and far from the public veterinary hospitals. Therefore, the morbidity rate and mortality rate at the highest spectrum of ranking and disease burden/disease load. The magnitude of disease problems was highest in the conventional based, lowest in the community based system and intermediate in the public based system. Better the quality of services are provided the minimal are the losses due to the diseases in the animal populations and in turn better the cost benefit ratio and ultimately the more prosperous is the farmer. The only way of poverty alleviation in the rural communities is to replicate the community based animal health services delivery system (Halla) with certain modifications in the Provinces of Punjab and Sindh in particular and in North West Frontier Province and Balochistan in general
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90.
Comparative Efficacy Of Guar (Gyamopsis Tetragonoloba) And Salinomycine Sodium Against Coccidiosis in Broiler Chicken
by Omer Naseer | Dr. Jawaria Ali Khan | Dr. Muhammad | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 2010Dissertation note: Parasitic diseases are major problems disturbing the poultry industry and coccidiosis is one of most dangerous diseases that affect the national economy. One hundred and twenty (120) day old broiler chicks free from coccidial infection were purchased from local market. The broiler chicks were divided into four groups viz. A, B, and I) each comprising of 30 birds. Each group was further divided into three replicates comprising 10 chicks each. All groups except group D was induced 10,000 sporocyst of Eimeria species orally on day 14th. Guts from the broiler chicks suspected with coccidiosis were collected from the field and local poultry farms. The coccidial oocysts in faeces were isolated and sporulated. Oocysts were collected from the gut samples. The counting of oocysts in samples was performed by McMaster technique. The experimental birds were vaccinated against various diseases i.e., Gumboro (IBI)) and Newcastle Disease.
Salinomycin and guar was used against coccidiosis as per medication protocol the dose rate of 5 gm/kg in feed and Sgm/95 gm of feed given to group A and B respectively. While group C consist of positive control and group I) was negative control. OPG, weight gain and FCR was also being recorded as well as postmortem was performed in case of mortality. For statistical analysis one way ANOVA technique was used.
It is concluded that Salinomycin 5 gm/kg in feed had shown best results in terms of maximum weight gain. FCR as compared to Guar 5gm/95 gm of feed which shown reduced oocyst count and mortality. It was not clear which specific compounds in guar contributes to the anticoccidial or growth inhibitory effects. Further research is needed to investigate whether the anticoccidiosis effect of guar was due to residual guar gum (galactomannans), saponins, or some unknown component of guar.
It is anticipated that the results of this study will help the poultry farmers and other concerned peoples to choose best possible drug to eradicate coccidiosis and take maximum production.
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91.
Prevalence Of Cestodes And Comparative Efficacy Of Niclosamide, Mebendazole And Fenbendazole In Pet Dogs
by Muhammad Shahid | Dr. Asim Khalid Mahmood | Prof. Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2010Dissertation note: This study was conducted to assess the prevalence of cestodes infestation in pet dogs in district Lahore and to evaluate the efficacy of niclosamide, mebendazole and fenbendazole against them. For this the samples were collected from three different clinics in Lahore for a period of 3 months. A total of 400 samples were collected. Three types of cestodes were identified (E.granulosus, T.hydatigena and D.caninum). The highest prevalence revealed was that of T.hydatigena and the lowest was of D.caninum in pet dogs. For the drug trials, 32 dogs were divided into four groups named group A (niclosamide), group B (mebendazole), group C (fenbendazole) and group D (positive control). The sampling was performed on day 0, 7 and 21 & the treatment with each drug was made on 0 and 7 days. Later on the reduction in EPG and the calculation of efficacy revealed that mebendazole is the best drug among the three drugs used and the efficacy of fenbendazole was found to be very poor.
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92.
A Comparative Study On Clinico -Hemotological & Therapeutic Trails In Indigestion & Lactic Acid In Small Ruminents
by Muhammed Abdul Basit | Dr. Syed Saleem Ahmad | Prof. Dr. Muhammad Sarwar Khan.
Material type: ; Format:
print
Publisher: 2010Dissertation note: The Indigestion and lactic acidosis are most common non infectious managmental problem in small ruminants that have been causing global concern as a potential threat. Some cases shows the clinical signs very early while some shows late clinical signs most of which arc common among these two diseases. So it is a matter of priority to develop quick and efficient methods for differential diagnosis and quick response of the therapeutical agent.
It was found that rectal temperature, Ruminal fluid pH, and ruminal movements decreased significantly in Indigestion and lactic acidosis in sheep and goats before the treatment in comparison to the control group. On the other hand it was observed that pulse and respiration rate were increased in both groups D-l and D-2 as compare to control group. In present study design, 2 groups of animals were designed for Indigestion and lactic acidosis (I for each disease). Each group was divided into 4 sub group each comprising 10 animals (sheep and goats). The group 1-1 of D-l was provided with Acetic Acid Vinegar 500-800 ml per animal per oral while 1-2 of D-l group was treated with Stomach powder @ 50-70 grams per animal per oral. Similarly sub group LA-l of D-2 was treated with sodium bicarbonate 5% 200-3 00 ml per animal intravenously and sub group LA-2 of D-2 group was provided with sodium bicarbonate @ 40-60 grams per animal per oral. On the other hand sub group 1-3 of D-l and LA-3 of D-2 was kept as diseased untreated control and subgroup 1-4 of indigestion group and LA-4 of Lactic acidotic group was kept as healthy control. Mean values obtained after treatment for D- I group (Indigestion) were rectal temperature increases more significantly in I-I than that of 1-2 while pulse rate of 1-2 sub group was significant than I-i. Respiration rate change was also significant in I- I sub group. Blood pH of 1-2 was significant while ruminal fluid p11 increases more significantly in 1-1. On the other hand mean values obtained allcr treatment for D-2 group (Lactic acidosis) were rectal temperature and pulse rate changed significantly in LA-i sub group. Respiration rate change was significant in LA-2 sub group Blood pit of LA-i & LA-2 in similar range while ruminal fluid pH increases more significantly in LA-I that LA-2 sub group.
Ruminal protozoa were not seen in ruminal fluid of both groups. Ruminal movements was rarely observed in indigestion group and not observed in lactic acidotic glol'').
Availability: Items available for loan: UVAS Library [Call number: 1167,T] (1).
93.
Descriptive Epidemiology Of Bovine Subclinical Mastitis And Non-Functional Teats
by Zaheer Hussain | Dr. Muhammad Athar Khan | Dr. Muhammad Sarwar Khan | Dr. Shakil | Faculty of Veterinary Sciences.
Material type: ; Format:
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; Literary form:
not fiction
Publisher: 2002Dissertation note: The study was conducted to understand the prevalence of subclinical mastitis prevalence of non-functional teats and various factors associated with it, viz lactation age, lactation number, housing and hygiene. The economical losses due to subclinical mastitis and non-functional teats were also estimated. Four village Munianwala, Kot Lehnadas, Rossy and Damiranwala and two private farms located in Jattan Tha Warda and Wazirpur were selected on the basis of availability and non-availability of veterinary medical services.
The prevalence of subclinical mastitis was found to be 39.46% (58 affected cattle out of 147 lactating cattle) in cattle and 29.13% (162 affected buffaloes out of 556 lactating buffaloes) in buffaloes on animal basis and 12.79% (37 affected quarters out of 2791 quarters at risk) on quarter basis collectively in both species.
The occurrence of subclinical mastitis was higher in hindquarters 60% than 40% in fore quarters. The prevalence of subclinical mastitis was recorded, 32.21%, 27.73%, 21.84% and 18.20% in right hind, left hind, left front and right front quarters respectively from 220 affected animals.
The prevalence of subclinical mastitis was highest in 5th and 6th lactation animals, 36.23% in buffaloes and 42.85% in cattle followed by 3rd and 4th lactation animals 32.57% in buffaloes and 39.39% in cattle and 1st and 2nd lactation animals 24.50% in buffaloes and 39.34% in cattle. The lowest prevalence of subclinical mastitis was in group of animals which were in > 6th lactation.
The highest prevalence of subclinical mastitis was observed in late stage of lactation in both buffaloes and cattle i.e. 33.65% and 56.09% respectively. The prevalence of subclinical mastitis was found 27.71% in buffaloes and 31.57% in cattle in mid stage of lactation and 26.11% in buffaloes and 34.66% in cattle in early stage of lactation.
The prevalence of subclinical mastitis in animals with poor, fair and good hygienic status was found to be 50%, 30.58% and 19.62% respectively.
The prevalence of non-functional teats was found to be 0.75% (21 non-functional teats out of 2812 quarters at risk) on quarter basis and 2.84% animals (n=20/703) had non-functional teats.
The economical losses due to non-functional were estimated to be Rs.340 per lactating animal and Rs.929 per farmer per annum. Losses due to subclinical mastitis were estimated to be Rs.536 per lactating animal and Rs.1467 per farmer per annum.
Availability: Items available for loan: UVAS Library [Call number: 1175,T] (1).
94.
Prevalence Of Caprine Mycoplasmosis In Different Areas Of Pakistan
by Waseem Shahzad | Prof. Dr. Mohammad Sarwar Khan | Prof. Dr. Muhammad Arif Khan.
Material type: ; Format:
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Publisher: 2010Dissertation note: A study was conducted to characterize caprine mycoplasma species and to know its prevalence in different areas of Pakistan during 2006 to 2007. For this purpose a total of 1440 different samples such as nasal discharge, pleural fluid, lung piece, synovial fluid, and milk samples (1180), and 260 serum samples were collected from clinically affected goats of different breeds, age and sex. These samples were collected from twelve districts including Mansehra, Peshwar, Swabi, Kohat, Abbottabad, Dera Ghazi Khan, Quetta, Pishin, Jhang, Sargodha, Lahore and Faisalabad with 6 union councils (UC) in each district. Twenty samples of different nature were collected from each of union council. These samples were subjected to cultural isolation, Growth inhibition test (GIT) using rabbit polyclonal antiserum against Mycoplasma mycoides subspecies capri, latex agglutination test (LAT) for the detection of Mycoplasma capricolum subspecies capripneumoniae and polymerase chain reaction (PCR). One twenty one samples out of 1180 showed turbidity in PPLO broth whereas out of these 121 samples 58 grew on PPLO agar. All 58 field isolated organisms showed positive reaction to GIT. None of the serum sample showed a positive reaction with LAT kit. Thirty five samples out of 1180 prior to culturing were positive for Mycoplasma mycoides cluster through PCR and identified as Mycoplasma mycoides subsp. capri (Mmc) through DNA sequencing, whereas 58 samples were positive with this technique after culturing. Prevalence of mycoplasmosis in hilly and plain areas (5.8 and 4.5 % respectively) is not significantly higher as compared to semi desert and sub hilly areas (3.3 and 2.9 % respectively) which may be due to chance alone. Furthermore, the adult group-3 (age > 1 year) has significantly lowest prevalence (2.7 %) of Mmc as compared to age group-1 (age < 181 days) with 5.1 % prevalance and age group-2 (age: 181 to 365 days) with 4.4 % prevalence. This difference may be due to chance but not areal difference. Similarly prevalence (4.7%) of mycoplasmosis in female goats is not significantly higher as compared to males (3.2%). Beetal, Piamiri, Beetal teddy cross, Baltistani and Desi breeds of goats showed higher prevalence only by chance as compared to other breeds in the areas under study. Saponin inactivated vaccine was prepared from this field strain and found to be effective against Mycoplasma mycoides subsp. capri in goats. This study focuses on characterizing the interaction of M. ovipneumoniae with ovine PBMC using carboxy-fluorescein-succinimidyl-ester (CFSE) loading and flow cytometry to measure lymphoid cell division. M. ovipneumoniae induced a strong in vitro polyclonal suppression of CD4+, CD8+, and B blood lymphocyte subsets. The suppressive activity could be destroyed by heating to 60 ºC, and partially impaired by formalin and binary ethyleneimine treatment that abolished its viability. The activity resided on the surface-exposed membrane protein fraction of the mycoplasma, since mild trypsin treatment not affecting viability was shown to reduce suppressive activity. Trypsintreated mycoplasma regained suppressive activity once the mycoplasma was allowed to re-synthesize its surface proteins. Implications for the design of vaccines against M. ovipneumoniae are discussed.
Availability: Items available for loan: UVAS Library [Call number: 1188,T] (1).
95.
A Study Of Giardiasis And Its Chemotherapy With Metronidazole And Albendazole In Dogs
by Ayesha sara | Dr. Jawaria Ali Khan | Prof. Dr. Muhammad Sarwar Khan.
Material type: ; Format:
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Publisher: 2010Dissertation note: Giardiasis is an intestinal pathogenic protozoan which infect humans and a wide range of animals including dogs prevalence of giardia varies widely depending on the detection method, geographic localization and population studied.
The objective of the study was to determine the percentage of giardiasis in dogs, its treatment and blood examination before and after treatment. The study was conducted in pet center of university of veterinary and animal sciences (UVAS) and private clinics in Lahore; collected sample were processed in medicine laboratory, department of clinical medicine and surgery (UVAS), Lahore.
Faecal samples of five hundred dogs suspected with giardiasis were collected and assessment of giardia cyst were seen using zinc sulphate floatation technique and sucrose gradient centrifugation method, then the positive dogs were separated and divided into four groups viz A, B, C, groups D was negative control, group A was treated with Metronidazole and its efficacy wasll.3 %,64 % & 85 % on day 31,5th & 7th day post treatment while group B was treated with Albendazole & its efficacy was 16.3 % ,44.2 % & 74 % on day 31,5th & 7th day post treatment the results showed that the Metronidazole was better in efficacy then Albendazole, C group was serve as positive control & all these results were compared with negative control (healthy dogs) that is group D.The efficacy of the drugs was determined by the disappearance of giardia cysts from feceas.
The blood examination total leukocyte count & Differential Leukocyte Count was conducted before & after the treatment with drugs & it showed that there was mild increase in TLC but not more increase in DLC & no adverse effect of drugs on blood parameters and values were almost normal and close to the values of negative control(healthy dogs).
It has been observed during the present study that metronidazole & albendazole showed their mild effect on blood parameters as a result of curing giardiasis.
Statistical analysis of data revealed non significant difference (p>O.O5) between groups, A, B, & D (-ye control) on day 3 & 7 of treatment. it was observed that metronidazole was the most effective 85% followed by albendazole 74% against giardiasis in dogs.
Availability: Items available for loan: UVAS Library [Call number: 1192,T] (1).
96.
A Study Of Parasitic Causes Of Diarrhea In Cattle Calves In District Gujranwala
by Muhammad Salman | Prof. Dr. Muhammad Sarwar Khan | Dr. Jawaria Ali Khan | Prof. Dr. Azhar.
Material type: ; Format:
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; Literary form:
not fiction
Publisher: 2010Dissertation note: The loss of fluids through diarrhea can- cause severe dehydration which is one cause of death on diarrhea sufferers. In present study cattle calves up to six months of age in district Gujranwala were examined for parasitic infestation. The samples were collected from different Government farms, veterinary hospitals and from villagers having livestock. A total number of 300 cattle calves were examined during the period of three months. The effect of parasitic diarrhea according to the factors like sex and age were studied, the percentage of parasitic diarrhea in cattle calves were also studied. Collected samples were processed at medicine laboratory of university of veterinary and animal sciences Lahore.
Fecal samples were processed for different coporological tests, including direct smear, floatation, sedimentation, McMaster and for cryptosporidial examination, staining of fecal smears were used. Blood parameters like Hemoglobin level, TLC & DLC was also be studied. The faecal samples result showed that 147 samples were positive from parasitic diarrhea out of 300 samples and percentage was 49 % including cryptosporidium, cooperia, oesophagostomum, fashiodorous, toxocara, coccidian & eurytrema. The samples were collected age wise as 0-1 months, 42 samples were positive out of 90 samples showing 46.6%, in 1-3 months 47 samples were positive out of 95 samples showing 49.47 %, 1n3- 6 months 58 samples were positive out of 115 showing 50.43 %.while the blood parameters Hb level, TLC & DLC were altered in parasitic diarrhea which showed milk decrease in TLC & DLC as compared to normal values while Hb level was also decreased in parasitic diarrhea.
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97.
Comparative Study Of Primary And Secondary Bloat In Buffaloes
by Sajjad Ahmad | Prof. Dr. Muhammad Sarwar Khan | Dr. Zia-ur-Rehman | Prof. Dr. M.
Material type: ; Format:
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Publisher: 2010Dissertation note: Bloat (tympany) is the abnormal distension of rumen and reticulum caused by excessive
gases of fermentation, either in the form of persistent foam mixed with rumen contents
or as free gas separated from the ingesta.
The experimental study on bloat was conducted at outreach clinic of university of veterinary and animal sciences, Lahore and adjacent areas. There were 500 buffaloes, out of these cases 86 were diagnosed to be suffered from bloat (60 were suffering from primary bloat, 2o were suffered from secondary bloat as shown in the table No 5 and table No 6). Six animals were expired from primary bloat as shown in the table No 10. They were expire without any treatment. Thus the disease percentage recorded was 17.4
A systemic clinical examination of each animal was conducted. The age, breed, sex and general heath of the animal was also recorded. Complete history of each affected animal was recorded. Diagnostic confirmation between primary bloat and secondary bloat was done through stomach tube. Primary bloat was easily recognizable and there were no other diseases of reticulorumen that result in ruminal tympany. Secondary bloat was differentiated from causes of failure of eructation including esophageal obstruction,chromic reticuloperitonitis, vagal indigestion, tetanus, injury and rumen impaction.
Treatment trials were carried out on the basis of grouping of animals. The buffaloes which are under attack of bloat were classified into two main groups i.e. group A and group B, which were further divided into four sub groups, which were A1, A2, B1 and B2.Animals suffered from primary bloat were kept into Group A1 and A2. While the animals suffering from secondary bloat were kept into Group B1 and Group B2. Treatment trials for Group A1 and Group B1 were same, while for Group A2 and Group B2 were same. The efficacy of drug was evaluated on reversal of clinical signs. The bloat affected buffaloes recovered with in 2 to 3 hours after the administration of medicine. No Side effects of these drugs, if any, was recorded the animals was examined for 24 hours after medication.
Availability: Items available for loan: UVAS Library [Call number: 1194,T] (1).
98.
Comparative Efficacy Of Intravesical Mucosal And Extravesical Apposition Techniques For Ureteroneocystostomy in Dogs
by Muhammad Talha Sajjad | Prof. Dr. Muhammad Arif Khan | Dr. Aneela | Dr. Shahan Azeem.
Material type: ; Format:
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; Literary form:
not fiction
Publisher: 2011Dissertation note: This project was designed to evaluate the comparative efficacy of two different techniques of Ureteroneocystostomy for ureteral reimplantation in dogs. Sixteen stray dogs were selected and were divided into two groups i.e. group A & B, comprising eight animals each. The efficacy of the procedures was evaluated on the basis of physical examination, serum evaluation for creatinine & urea, contrast radiography and post mortem findings.
The surgery was conducted through ventral midline celiotomy from umbilicus to a variable distance caudally under general anesthesia in both the groups and urinary bladder was exteriorized in both the groups. In group A, longitudinal incision was made near the bladder dome, a mosquito hemostat was passed from the surface of the bladder through the bladder wall at an oblique angle then the ureter was brought to the level of the bladder mucosa incision. A 6-0 Polyglactin 910 (Vicyrl,Jhonsons & Jhonsons Pharma) suture with double needles was then placed at each apex of the spatulated ureter and the full-thickness of ureter anastomosed to the bladder mucosa in one layer with a continuous, nonlocking stitch. In group B, two small incisions were made at the outer part of the bladder wall until the mucosa was seen through the cuts. Then a submucosal tunnel was dissected between them and the graft's ureter was introduced. Once the ureteral end has been spatulated, a reabsorbable 4-0 suture thread with independent needles at each end was passed (each needle goes from the outer to the inner side of the ureteral wall. Afterward, both needles were advanced into the bladder by the creation of a mucosal incision at the distal hole; these two needles then transfixed the bladder wall
from inside about 2 cm distally. During knotting of the suture (outside the bladder) the distal ureter was pushed to the bladder wall that it anchored against the mucosa.
The results of this study clearly indicated that both techniques are equally effective for the reimplantation of the ureter to bladder but an extravesical ureteroneocystostomy (Modified Lich Gregoir) has an edge over in intravesical mucosal apposition technique (Modified Lead better-Politano) in terms of effectiveness , safety and minimum postoperative complications.
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99.
Epidemiology Diagnosis And Chemotherpy Of Strangles In Equines
by Muhammad Ijaz | Prof. Dr. Muhammad Sarwar Khan | Prof. Dr. Muhammad Arif Khan.
Material type: ; Format:
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Publisher: 2010Dissertation note: Strangles is an infectious malady of equidae characterized by upper respiratory tract infection, dysponea, anorexia, regional suppurative lymphadenitis and causes high morbidity and low mortality. Considering the significance and utilization of equines in our country and the substantial losses rendered by Strangles, the present project was designed to study epidemiology, diagnosis and chemotherapy of strangles in Lahore and Sargodha districts of the Punjab province in Pakistan.
The present study comprised of five phases. In phase-I, epidemiology of the disease including prevalence, variations in SeM, SzPSe and Se18.9 proteins and mortality rate were studied in Lahore and Sargodha districts. For epidemiology, nasal swabs and pus samples from the affected lymph nodes of 500 equines (nr=250 horses, rutz250 mules) suspected for strangles were collected and cultured for identification of S. equl. The collected samples were processed at Medicine and Microbiology Laboratories of the University of Veterinary and Animal Sciences, Lhore, Pakistan and Gluck equine research center, Department of Veterinary Science, University of Kentucky, USA. Out of 250 horses and 250 mules, 113(45.2%) horses and 99 (3 9.6%) mules tested positive for S. equi. on the basis of culture. Number of S. equl isolates were significantly higher (P<0.05) in pus samples taken from sub-mandibular lymph nodes as compared to nasal discharge samples. The difference was significant (P<0.05) among mules of different age groups. The highest prevalence of strangles
was recorded in horses and mules less than 2 year of age as compared to those having age more than 2 years.
In the present study, prevalence of strangles round the year in horses and mules were also calculated and it was found to be the highest during the months of
February, March, April and May while few cases were seen during the months of January, June and July and no cases were observed during others months. The significant difference was observed (p<O.O5) among the prevalence levels of strangles in different months of the year. Similarly when compared the prevalence of strangles in different seasons of Pakistan i.e. summer, winter, spring and autumn. The highest prevalence rate was recorded during the spring season.
The prevalence on the basis of Polymerase chain reaction (PCR) of S. equi in horses and mules was also recorded. Out of 250 horses and 250 mules tested, 122(48.8%) horses and 113(45.2%) mules were positive for S. equi. When compared
the prevalence rate on the basis of PCR and culture of nasal and pus samples from affected submandibular lymph nodes it revealed that the sensitivity of Polymerase
chain reaction appears to be much greater than culture. The culture along with PCR is the best diagnostic technique for S. equi as PCR test does not differentiate between dead and live bacteria, hence a positive test may not correlate with active infection; therefore, a positive culture may be necessary to confirm the diagnosis.
In this phase of epidemiological study of disease, effect of selective pressure of allelic diversity in SeM of S. equi on immunoreactive proteins SzPSe and Se 18.9 was also studied. The aim of this study was to determine whether variations in SeM are accompanied by variations in the immunoreactive surface of exposed SzPSe and secreted Se18.9. Sequences of genes of 25 S. equi alleles isolated from different countries of the world over a period of 40 years were compared. Twenty different SeM alleles were identified including 6 not included in the data base (http:// pubmlst.org/szooepidemicus). Amino acid variation was also detected distal to the N- terminus of SeM. No variation was observed in SzPSe except for an Australian isolate which showed a deletion of one PEPK repeat. The Se 18.9 protein in all 25 isolates of S. equi did not exhibit any variation. Interestingly, only 2 SNP loci were detected in Se 18.9 compared to 93 and 49 in SeM and SzPSe respectively. The greater frequency of mutation in SzPSe compared to Se18.9 may be related to a high rate of recombination of SzPSe and the inclusion of exogenous DNA sequence based on the atypical GC percentage of its central hyper variable region.
In horses the mortality rate was recorded as 1.64% whereas the mortality rate in mules having less than 5 years of age was found to be 0.88%. No significant difference (P>0.05) in mortality rate among horses and mules of different age groups affected with strangles was observed.
In phase-I! of the present study, carrier status of the horses and mules were
studied. Out of 122 horses found positive to PCR, 20 horses (10<2 years and 10 between 2 and 5 years of age) were selected and monitored for 12 weeks. Their nasal
swab samples were used for identification of bacteria through culture and PCR on weekly basis. Till the end of 3rd week all horses <2 years of age remained positive but at the end of 4th to 7th weeks there remained positive only 5, 2, 1 and zero horses out of 10, respectively on the basis of culture whereas through PCR at the end of the 4th week all horse <2 years of age were found positive, but at the end of 5th to 10th weeks there remained 7, 5, 4, 2, 1 and zero horses out of 10, respectively. While all the horses aging between 2 to 5 year, were positive up to the 1St week but at the end of 2nd to 8th week out of 10 there were 9, 7, 6, 3, 1, 1 and zero horses respectively positive on the basis of culture but through PCR, all horses were positive till 4th week but at the end of 5th to 9th week number was reduced to 9, 7, 6, 3, 2 and zero. Similarly, out of 113 mules, 20 mules (10<2 year and 10 between 2 and 5 years of old) were also monitored for 12 weeks to study their carrier status. After the end of 2nd week all mules <2 years of age were positive but at the end of 3rd to 6th weeks there remained 7, 3, 1 and zero mules out of 10, respectively on the basis of culture but through PCR at the end of the 5th week all mules <2 years of age were positive, but at the end of 6th to 10th weeks there remained 9, 7, 3, 2 and zero mules out of 10, respectively. While in 2 and 5 year old mules, all were positive up to the 2nd week but at the end of 3rd to 7th weeks there were 6, 4, 2, 1, 1 and zero mules out of 10, respectively on the basis of culture but through PCR, all mules were positive up to 5th week but at the end of 6th to 10th weeks there were 8, 5, 2, 1 and zero. Horses and mules were declared free of infection on the basis of three consecutive negative samples through culture and PCR.
From the result of present study, it may be concluded that sensitivity of Polymerase Chain Reaction appears to be much greater than culture for study of carrier status of equines. Moreover, recovered animals should be kept in quarantine period at least upto 9th week because the recovered horses and mules remain carrier for prolonged period of time and can act as source of infection for susceptible animals through periodic shedding of S equi. (comprising 10 horses and 10 mules) for in-vivo trials. Efficacy of the antibiotics was assessed weekly on the basis of negative nasal swab culture. Results of in-vitro antibiotic sensitivity revealed that in horses and mules, S equi was most sensitive to Procaine penicillin followed by ceftiofur Na, cephradine, erythromycin, ampicillin, tetracycline, chloramphenicol, sulfamethoxazole, trimethoprim + sulfdiazine and gentamycin whereas the result of in-vivo antibiotic trials revealed that horses and mules suffered from strangles without abscess formation were most sensitive to Procaine penicillin followed by ceftiofur Na, cephradine and erythromycin whereas animals which developed abscess showed no response. It is concluded from the result of present study that Procaine penicillin is most effective in-vitro and in-vivo antibiotic followed by ceftiofur Na and cephradine. These antibiotics might be used for the treatment of strangles infection.
Phase-V, comprised over in-vitro trials of disinfectants. Efficacy of disinfectants, like povidone iodine, 0.6% H2S04, dettol and bleach was assessed. Phenol Co-efficient Test was applied, to ascertain efficacy of these disinfectants, used
in, in-vitro trials. Among four disinfectants, povidone iodine was found to be the best one with a phenol coefficient of 1.25 that is greater than phenol i.e. 1.00 while 0.6%
H2S04 showed similar phenol coefficient as that of phenol. The phenol coefficient of dettol and bleach were observed as 0.5 and 0.75 respectively. Therefore it is recommended that S. equi is highly sensitive to povidone iodine and 0.6% H2S04.
Availability: Items available for loan: UVAS Library [Call number: 1211,T] (1).
100.
Comparative Efficacy Of Suturing Techniques And Suture Materials For End-To-End Anastomosis Of Small Intestine in Dogs
by Adeel Shahbaz | Prof Dr. Muhammad Arif Khan | Mr. Shahan Azeem | Prof. Dr.
Material type: ; Format:
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Publisher: 2010Dissertation note: The small intestine is a tube-like structure, which extends between the stomach and largeintestine. It starts at the pylorus and terminates at the cecocolic junction. Small intestine plays an important role in the absorption of amino acids, carbohydrates, fats and electrolytes like sodium, potassium, chloride and bicarbonate ions. Any disease condition of jejunum like neoplasia or devitalization due to foreign body necessitates the resection of it. This project was designed to evaluate the comparative efficacy of different suturing techniques and suture material applied during end-to-end anastomosis of small intestine. The study was designed on eighteen stray dogs. The dogs were divided into 3 groups i.e group A, B, and C comprising 6 animals each. Each group was further subdivided into the subgroups as, Al, A2, Bi, B2 and Cl, C2. The dogs of group A was numbered from 1-6, group B from 7-12, and group C from 13-18 for the identification purpose. The surgery was conducted through ventral midline celiotomy from umbilicus to a variable distance caudally under general anesthesia. In group A, Simple interrupted, group B modified Gambee and in group C interrupted Lembert suturing technique for end-to-end anastomosis of small intestine was used. In subgroup Al, B, C! chromic catgut and in subgroup A2, B2 an C3 polyglyconate suture materials was used.
In group Cl, operated dog No.2 died on day 16 post operatively. The versatility and comparison of the techniques were evaluated on the basis of health status including vomiting, diarrhea, and weight gain or weight loss, wound healing, radiographic assessment, decrease in lumen diameter, alignment of tissue plane and quality of wound healing of the anastomotic site in all three group A, B and C. The leakage was checked at 2, 4, 6 and 12 week post surgery using contrast radiographs. During the study period the dogs were housed in the kennels available at Surgery Section, Department of Clinical Medicine and Surgery, University of Veterinary and Animal Sciences, Lahore.
The present project is clearly indicated that modified Gambee suturing technique was found to be more suitable and compatible anastomotic technique with excellent clinical superiority. It resulted in the batter wound healing, minimal lekage, minimal reduction in lumen diameter at the anastomotic site, excellent in its alignment of tissue plane, satisfactory clinical layer to layer healing , is simple to duplicate under field conditions and minimal abdominal complication.
Availability: Items available for loan: UVAS Library [Call number: 1218,T] (1).
